Efficient operator method for modeling mode mixing in misaligned optical cavities

The transverse field structure and diffraction loss of the resonant modes of Fabry-Pérot optical cavities are acutely sensitive to the alignment and shape of the mirror substrates. We develop extensions to the mode-mixing method applicable to arbitrary mirror shapes, which both facilitate fast calculation of the modes of cavities with transversely misaligned mirrors and enable the determination and transformation of the geometric properties of these modes. We show how these methods extend previous capabilities by including the practically motivated case of transverse mirror misalignment, presenting the ability to study the rich and complex structure of the resonant modes

Genetic-geographic correlation revealed across a broad European ecotypic sample of perennial ryegrass (Lolium perenne) using array-based SNP genotyping

KEY MESSAGE: Publically available SNP array increases the marker density for genotyping of forage crop,Lolium perenne. Applied to 90 European ecotypes composed of 716 individuals identifies a significant genetic–geographic correlation. ABSTRACT: Grassland ecosystems are ubiquitous across temperate and tropical regions, totalling 37 % of the terrestrial land cover of the planet, and thus represent a global resource for understanding local adaptations to environment. However, genomic resources for grass species (outside cereals) are relatively poor. The advent of next-generation DNA sequencing and high-density SNP genotyping platforms enables the development of dense marker assays for population genetics analyses and genome-wide association studies. A high-density SNP marker resource (Illumina Infinium assay) for perennial ryegrass (Lolium perenne) was created and validated in a broad ecotype collection of 716 individuals sampled from 90 sites across Europe. Genetic diversity within and between populations was assessed. A strong correlation of geographic origin to genetic structure was found using principal component analysis, with significant correlation to longitude and latitude (P < 0.001). The potential of this array as a resource for studies of germplasm diversity and identifying traits underpinning adaptive variation is highlighted. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00122-015-2556-3) contains supplementary material, which is available to authorized users

Mode mixing and losses in misaligned microcavities

We present a study on the optical losses of Fabry-P\'erot cavities subject to realistic transverse mirror misalignment. We consider mirrors of the two most prevalent surface forms: idealised spherical depressions, and Gaussian profiles generated by laser ablation. We first describe the mode mixing phenomena seen in the spherical mirror case and compare to the frequently-used clipping model, observing close agreement in the predicted diffraction loss, but with the addition of protective mode mixing at transverse degeneracies. We then discuss the Gaussian mirror case, detailing how the varying surface curvature across the mirror leads to complex variations in round trip loss and mode profile. In light of the severe mode distortion and strongly elevated loss predicted for many cavity lengths and transverse alignments when using Gaussian mirrors, we suggest that the consequences of mirror surface profile are carefully considered when designing cavity experiments.Comment: 16 pages, 12 figure

Efficient operator method for modelling mode mixing in misaligned optical cavities

The transverse field structure and diffraction loss of the resonant modes of Fabry-P\'erot optical cavities are acutely sensitive to the alignment and shape of the mirror substrates. We develop extensions to the `mode mixing' method applicable to arbitrary mirror shapes, which both facilitate fast calculation of the modes of cavities with transversely misaligned mirrors and enable the determination and transformation of the geometric properties of these modes. We show how these methods extend previous capabilities by including the practically-motivated case of transverse mirror misalignment, unveiling rich and complex structure of the resonant modes.Comment: 17 pages, 7 figure

Optimisation of Scalable Ion-Cavity Interfaces for Quantum Photonic Networks

In the design optimisation of ion-cavity interfaces for quantum networking applications, difficulties occur due to the many competing figures of merit and highly interdependent design constraints, many of which present `soft-limits', amenable to improvement at the cost of engineering time. In this work we present a systematic approach to this problem which offers a means to identify efficient and robust operating regimes, and to elucidate the trade-offs involved in the design process, allowing engineering efforts to be focused on the most sensitive and critical parameters. We show that in many relevant cases it is possible to approximately separate the geometric aspects of the cooperativity from those associated with the atomic system and the mirror surfaces themselves, greatly simplifying the optimisation procedure. Although our approach to optimisation can be applied to most operating regimes, here we consider cavities suitable for typical ion trapping experiments, and with substantial transverse misalignment of the mirrors. We find that cavities with mirror misalignments of many micrometres can still offer very high photon extraction efficiencies, offering an appealing route to the scalable production of ion-cavity interfaces for large scale quantum networks

Eight-year-olds identified in infancy as at risk of harm: report of a prospective longitudinal study

Eight-year-olds identified in infancy as at risk of harm: report of a prospective longitudinal stud

Prospectus, October 10, 1979

WORLD PREMIERE AT PC; WPCD Top 20; Foreigners plan celebration; Stugo surveys spring break; S.T.O. to give keg in raffle; Leslie views Parkland as an advantage; Survey will help design new food facilities; Nursing gets rolling with record enrollment; Child rearing at PC; Parkland Food Survey; Three part life at PC; Calif. group at PC Tues.; Avionics meeting; Feature: Numbers unimportant, just good music for Irish; Rally for no taxes Monday; Concerts: Kansas stages show; WPCD to add new program; Classifieds; EMT workshop conducted at PC; Prospectus to publish Images; Reviews: \u27Runner\u27 doesn\u27t stumble, Python religion, Buffest sings about islands, and islands, Talking Heads unafraid of the fear of music; V-ball sees the light, look for good week; Women Cobras prepare for season; Freddy continues loss skein; Fast Freddy Contest; Intramural Standingshttps://spark.parkland.edu/prospectus_1979/1009/thumbnail.jp

Maternal Metformin Intervention during Obese Glucose-Intolerant Pregnancy Affects Adiposity in Young Adult Mouse Offspring in a Sex-Specific Manner.

BackgroundMetformin is commonly used to treat gestational diabetes mellitus. This study investigated the effect of maternal metformin intervention during obese glucose-intolerant pregnancy on the gonadal white adipose tissue (WAT) of 8-week-old male and female mouse offspring.MethodsC57BL/6J female mice were provided with a control (Con) or obesogenic diet (Ob) to induce pre-conception obesity. Half the obese dams were treated orally with 300 mg/kg/d of metformin (Ob-Met) during pregnancy. Gonadal WAT depots from 8-week-old offspring were investigated for adipocyte size, macrophage infiltration and mRNA expression of pro-inflammatory genes using RT-PCR.ResultsGestational metformin attenuated the adiposity in obese dams and increased the gestation length without correcting the offspring in utero growth restriction and catch-up growth caused by maternal obesity. Despite similar body weight, the Ob and Ob-Met offspring of both sexes showed adipocyte hypertrophy in young adulthood. Male Ob-Met offspring had increased WAT depot weight (p p p F4/80 (p ConclusionsMaternal metformin intervention during obese pregnancy causes excessive adiposity, adipocyte hyperplasia and WAT inflammation in male offspring, highlighting sex-specific effects of prenatal metformin exposure on offspring WAT

SARS-CoV-2 Antibody Prevalence Among Healthcare Workers and First Responders, Florida, May-June, 2020

Background: The SARS-CoV-2 virus responsible for severe respiratory infection associated with coronavirus disease 2019 (COVID-19) was first confirmed in Florida on March 1, 2020. Responding to the pandemic, multi-agency collaborative partnerships put in place actions integrating point-of-care antibody testing at established large-scale COVID-19 testing sites where the baseline seropositivity of COVID-19 in health care workers and first responders in Florida at the start of the pandemic was established. Purpose: Determine the seropositivity of healthcare workers and first responders at five drive thru testing sites using a rapid SARS-CoV-2 antibody test in Florida from May 6 through June 3, 2020. Methods: The first drive-thru SARS-CoV-2 antibody test site was opened at Miami Hard Rock Stadium, May 6, 2020. Testing expanded to three additional sites on May 9, 2020: Jacksonville, Orlando, and Palm Beach. The fifth and final site, Miami Beach, began testing on May 21, 2020. Healthcare workers and first responder’s self-seeking SARS-CoV-2 testing were designated for antibody testing and completed a laboratory collection form on-site for the point-of-care test. All testing was performed on whole blood specimens (obtained by venipuncture) using the Cellex Inc. qSARS-CoV-2 IgG/IgM Rapid Test. Seropositivity was assessed by univariate analysis and by logistic regression including the covariates age, sex, race/ethnicity, and testing location. Results and Discussion: As of June 3, 2020, of 5,779 healthcare workers and first responders tested, 4.1% were seropositive (range 2.6–8.2%). SARS-COV-2 antibody tests had higher odds of being positive for persons testing at the Miami Hard Rock Stadium (aOR 2.24 [95% C.I. 1.48-3.39]), persons of Haitian/Creole ethnicity (aOR 3.28 [95% C.I. 1.23-8.72]), Hispanic/Latino(a) ethnicity (aOR 2.17 [95% C.I. 1.50-3.13], and Black non-Hispanic persons (aOR 1.63 [95% C.I. 1.08-2.46]). SARS-COV-2 antibody prevalence among first responders and healthcare workers in five sites in Florida varied by race and ethnicity and by testing location

Reference to the index of 2 scrapbooks compiled by sisters Susannah Jane Earle and Myrtle Walker. Their father was Thomas Blackmore (1848-1929 or 30), farmer of Nugent, and their mother was Louisa Maria, daughter of B Reardon of Forcett.

Both scrapbooks contain mostly undated cuttings from unidentified but chiefly local newspapers (e.g Hobart Mercury and Tasmanian Mail), and magazines (e.g Sydney Bulletin and Mirror). Often cuttings are from Saturday supplements or the 'Pink Page' of the Bulletin. Topics reflect women's interests: anecdotes and folklore; poems and stories by Australian authors {e.g article about Marie Bjelke Peterson, Tasmania, novelist(; local history (e.g paragraph about descendents living in Tasmania of Capt. Michael Connor of the First Fleet); news of members of the family (e.g brother, A R Blackmore enlists and resigns from teaching at Adventure bay School)