Alien Registration- Thibodeau, Alfred J. (Van Buren, Aroostook County)

https://digitalmaine.com/alien_docs/32233/thumbnail.jp

Alien Registration- Thibodeau, Alfred J. (Van Buren, Aroostook County)

https://digitalmaine.com/alien_docs/32220/thumbnail.jp

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.

Contains fulltext : 70723.pdf (publisher's version ) (Closed access)We conducted a genome-wide SNP association study on prostate cancer on over 23,000 Icelanders, followed by a replication study including over 15,500 individuals from Europe and the United States. Two newly identified variants were shown to be associated with prostate cancer: rs5945572 on Xp11.22 and rs721048 on 2p15 (odds ratios (OR) = 1.23 and 1.15; P = 3.9 x 10(-13) and 7.7 x 10(-9), respectively). The 2p15 variant shows a significantly stronger association with more aggressive, rather than less aggressive, forms of the disease