Neutrino oscillation studies with laser-driven beam dump facilities

A new mechanism is suggested for efficient proton acceleration in the GeV energy range; applications to non-conventional high intensity proton drivers and, hence, to low-energy (10-200 MeV) neutrino sources are discussed. In particular we investigate possible uses to explore subdominant $\bar{\nu}_\mu \to \bar{\nu}_e$ oscillations at the atmospheric scale and their CP conjugate. We emphasize the opportunity to develop these facilities in conjunction with projects for inertial confined nuclear fusion and neutron spallation sources.Comment: 30 pages, 9 figures, minor changes, version to appear in Nucl.Instrum.Meth.

Effects of citric acid and fibronectin and laminin application in treating periodontitis

. To determine the effect on new connective tissue attachment of citric acid conditioning and fibronectin-laminin application in treating naturally occurring periodontitis, all 4 quadrants in each of 2 Beagle dogs were used. Each quadrant included: P 2 , P 3 , P 4 , and M 1 teeth. 2 treatment modalities were employed and comparatively analyzed for differences in histological healing respponses at 120 days after surgery. The treatments were: (1) surgery (mucoperiosteal flaps) plus citric acid; (2) surgery plus citric acid followed by fibronectin-laminin application. After scaling and root planing, coronal and root surface reference notches were placed for histometric measurements. Following each of the randomly assigned treatments, flaps were sutured. After sacrifice, tissue blocks of treated areas were decalcified and serially cut, obtaining bucco-lingual and mesiodistal sections. Using a Filar micrometer. 5 distances were masured on the buccal aspect: (1) from root surface notch to alveolar bone crest; (2) from root surface notch to coronal extent of the cementum; (3) from root surface notch to apical extent of the junctional epithelium; 84) from free gingival margin to apical extent of junctional epithelium; (5) from the coronal notch to the alveolar bone crest. Results showed no differences among the 5 measurements between the 2 treatments tested. On mesiodistal sections, surface area determinations were made in the furcations, evaluating the space occupied by new connective tissue, with or without bone, or by epithelium. For this, images were digitized using a Zeiss IBAS Image analysis system with a 4mB of array processor memory coupled to a Newvicon TV camera and a microcomputer. Significant differences were found, with increased values for both regenerative connective tissue and bone when surgery plus citric acid was followed by fibronectin-laminin application. Often, these tissues filled completely furcation areas above root surface reference notches.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73686/1/j.1600-051X.1987.tb01543.x.pd

An electromagnetic shashlik calorimeter with longitudinal segmentation

A novel technique for longitudinal segmentation of shashlik calorimeters has been tested in the CERN West Area beam facility. A 25 tower very fine samplings e.m. calorimeter has been built with vacuum photodiodes inserted in the first 8 radiation lengths to sample the initial development of the shower. Results concerning energy resolution, impact point reconstruction and electron/pion separation are reported.Comment: 13 pages, 12 figure

Dreaming experience as a useful diagnostic clue for syncopal episodes

BACKGROUND: The differential diagnosis between epileptic seizures and syncopes is a common occurrence in clinical practice. The manifestations of seizure and syncope sometimes overlap, and available diagnostic testing often not provides a conclusive answer. Syncope is often preceded by a symptom complex characterized by lightheadedness, generalized muscle weakness, giddiness, visual blurring, tinnitus, and gastrointestinal symptoms. These subjective symptoms are very important in guiding the diagnosis. In our experience, the impression of coming out of a dream after the syncopal episode is a subjective symptom commonly reported by patients, if questioned. METHODS: To verify the occurrence of dreaming experience after syncope and after generalized tonic-clonic seizures (GTCS) and its diagnostic value in differential diagnosis, we asked 100 patients with GTCS and diagnosis of idiopathic generalized epilepsy (Group 1) and 100 patients with a certain diagnosis of syncope (Group 2) whether they have never felt the impression of coming out of a dream after the loss of consciousness (GTCS or syncope, respectively). RESULTS: In Group 1, nobody referred the dreaming experience, whereas in the syncope group, 19% of patients referred this subjective symptom. CONCLUSIONS: Dreaming experience seems to be an additional useful diagnostic clue for syncopal episodes, helping the clinician to differentiate them from seizures

Cognitive processess and cognitive reserve in multiple sclerosis

Multiple Sclerosis (MS) is characterized by motor, cognitive, and neuropsychiatric symptoms, which can occur independently. While MS is traditionally considered an inflammatory disease of the white matter, degeneration of gray matter is increasingly recognized as an important contributor to the progressive cognitive decline. A protective factor against the progression of cognitive dysfunction in MS could be the cognitive reserve, defined as resistance to brain dysfunction. Aim of the present study is to evaluate the role of cognitive reserve for different aspects of cognitive dysfunction of patients with MS. We found that patients with MS and lower cognitive reserve have poorer neuropsychological performance and slower information speed processing. These findings support the notion that intellectual reserve may protect some aspects of cognitive function in patients with MS

An innovative and viable routre for the realization of ultra-thin supercapacitor electrodes assembled with carbon nanotubes

Electrochemical Double Layer Capacitors (EDLC), also known as supercapacitors, have been fabricated using Single Walled Carbon Nanotubes (SWCNTs) as active material for electrode assembling. In particular a new way of fabrication of ultra-thin electrodes (≤25 m) directly formed on the separator has been proposed, and a prototype of EDLC has been realized and tested. For such devices the specific capacitance is in the range 40–45 F/g and the internal resistances in the range 6–8 ·cm2, at current density of 2 mA·cm−2. Keywords: Carbon Nanotube, Supercapacito

Abnormal plasticity of sensorimotor circuits extends beyond the affected body part in focal dystonia

Objective: To test whether abnormal sensorimotor plasticity in focal hand dystonia is a primary abnormality or is merely a consequence of the dystonic posture. Methods: This study used the paired associative stimulation (PAS) paradigm, an experimental intervention, capable of producing long term potentiation (LTP) like changes in the sensorimotor system in humans. PAS involves transcranial magnetic stimulation combined with median nerve stimulation. 10 patients with cranial and cervical dystonia, who showed no dystonic symptoms in the hand, and nine patients with hemifacial spasm (HFS), a non-dystonic condition, were compared with 10 healthy age matched controls. Motor evoked potential amplitudes and cortical silent period (CSP) duration were measured at baseline before PAS and for up to 60 min (T0, T30 and T60) after PAS in the abductor pollicis brevis and the first dorsal interosseus muscles. Results: Patients with dystonia showed a stronger increase in corticospinal excitability than healthy controls and patients with HFS. In addition, patients with dystonia showed a loss of topographical specificity of PAS induced effects, with a facilitation in both the median and ulnar innervated muscles. While PAS conditioning led to a prolonged CSP in healthy controls and patients with HFS, it had no effect on the duration of the CSP in patients with cranial and cervical dystonia. Conclusion: The data suggests that excessive motor cortex plasticity is not restricted to the circuits clinically affected by dystonia but generalises across the entire sensorimotor system, possibly representing an endophenotypic trait of the disease

Field emission properties of carbon nanotube arrays grown in porous anodic alumina

AbstractCarbon nanotubes (CNTs), with their excellent electronic properties and extremely high aspect ratio, represent an ideal material for building electron sources based on field emission. Fowler‐Nordheim equation describes quite successfully the field emission phenomenon, especially for single or isolated tips. However, some complications arise when populations of CNTs are considered, where collective effects and large variability in the emitters features influence the measured I–V characteristics. In this work, the emission properties of multi‐walled CNTs grown within ordered anodic alumina templates are investigated. These CNT matrices produce current densities up to some tens of mA/cm2, and the field enhancement factor for collective emission sources can be estimated. Such material can be modelled as an ordered and uniform array of emitters and a simulation of the electrostatic field on the emission tips can be done in order to evaluate the field enhancement factor and its dependence on various geometries. This allows comparing predictions from simulation and experimental measurements, in a direct way. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

An electromagnetic shashlik calorimeter with longitudinal segmentation

A novel technique for longitudinal segmentation of shashlik calorimeters has been tested in the CERN West Area beam facility. A 25 tower e.m. calorimeter has been built with vacuum photodiodes inserted in the first 8 radiation lengths to sample the initial development of the shower. Results concerning energy resolution, impact point reconstruction and $e/\pi$ separation are reported.A novel technique for longitudinal segmentation of shashlik calorimeters has been tested in the CERN West Area beam facility. A 25 tower very fine samplings e.m. calorimeter has been built with vacuum photodiodes inserted in the first 8 radiation lengths to sample the initial development of the shower. Results concerning energy resolution, impact point reconstruction and electron/pion separation are reported

Neutrino hierarchy from CP-blind observables with high density magnetized detectors

High density magnetized detectors are well suited to exploit the outstanding purity and intensities of novel neutrino sources like Neutrino Factories and Beta Beams. They can also provide independent measurements of leptonic mixing parameters through the observation of atmospheric muon-neutrinos. In this paper, we discuss the combination of these observables from a multi-kton iron detector and a high energy Beta Beam; in particular, we demonstrate that even with moderate detector granularities the neutrino mass hierarchy can be determined for $\theta_{13}$ values greater than 4$^\circ$.Comment: 16 pages, 7 figures. Added a new section discussing systematic errors (sec 5.2); sec.5.1 and 4 have been extended. Version to appear in EPJ