Beyond Speciesism

Current primate research has yielded stunning results that not only threaten our underlying assumptions about the cognitive and communicative abilities of nonhuman primates, but also bring into question what it means to be human. At the forefront of this research, Sue Savage-Rumbaugh recently has achieved a scientific breakthrough of impressive proportions. Her work with Kanzi, a laboratory-reared bonobo, has led to Kanzi\u27s acquisition of linguistic and cognitive skills similar to those of a two and a half year-old human child. Apes, Language, and the Human Mind skillfully combines a fascinating narrative of the Kanzi research with incisive critical analysis of the research\u27s broader linguistic, psychological, and anthropological implications. The first part of the book provides a detailed, personal account of Kanzi\u27s infancy, youth, and upbringing, while the second part addresses the theoretical, conceptual, and methodological issues raised by the Kanzi research. The authors discuss the challenge to the foundations of modern cognitive science presented by the Kanzi research; the methods by which we represent and evaluate the abilities of both primates and humans; and the implications which ape language research has for the study of the evolution of human language. Sure to be controversial, this exciting new volume offers a radical revision of the sciences of language and mind, and will be important reading for all those working in the fields of primatology, anthropology, linguistics, philosophy of mind, and cognitive and developmental psychology.https://scholarworks.wm.edu/asbookchapters/1129/thumbnail.jp

STR-995: CALIBRATION OF AN ANALYTICAL METHOD FOR VEHICLE-INDUCED VIBRATIONS ON FLEXIBLE BRIDGES

The results of full scale trials of heavy vehicle-induced vibrations on the Pierre Laporte Bridge are presented. The Pierre Laporte Bridge spans approximately 1 km having the longest main span of any suspension bridge in Canada. The tests were performed during short periods of complete bridge closure on October 27 and 28, 2014. During the tests, the acceleration of the bridge was recorded at multiple locations in addition to measurements of the vertical and pitching accelerations of the testing vehicle itself. The results of these tests are used to calibrate an analytical tool developed to screen bridge designs for potential serviceability concerns due to vehicle-induced vibrations. Numerical simulations are performed using this analytical method and compared directly to the results of the full scale trials. Good agreement is found between the peak predictions and the measurements highlighting the effectiveness of the screening tool during the design of medium- to long-span bridges. No cases of pedestrian discomfort to any kind of dynamic excitations have been reported since the Pierre Laporte Bridge opened in 1970, and the results measured during the full scale trials and those simulated numerically reflect these observations

Hepatitis B knowledge and practices among Cambodian Americans.

Liver cancer occurs more frequently among Americans of Southeast Asian descent than any other group. This health disparity can be attributed to high rates of hepatitis B virus (HBV) infection. We examined HBV awareness, knowledge about HBV transmission, HBV testing levels, and HBV vaccination levels among Cambodian Americans

Factors associated with hepatitis B testing among cambodian american men and women.

Cambodian Americans have an elevated risk of liver cancer. This health disparity is attributable to high rates of hepatitis B virus (HBV) infection. Our study examined factors associated with HBV testing among Cambodian men and women. A population-based survey was conducted in the Seattle area. The Health Behavior Framework guided our survey instrument development. We attempted to interview a man and a woman in each household. The sample included 300 men and 367 women. About one-half of the male (45%) and female (54%) respondents had been tested for HBV. Two factors were independently associated with testing among men and women: a doctor had recommended testing and had asked a doctor for testing. Knowing that someone who looks and feels healthy can spread HBV was independently associated with testing among men. Low levels of HBV testing remain a public health problem among Cambodians. Interventions should improve patient-provider communication by encouraging providers who serve Cambodians to recommend HBV testing, as well as by empowering Cambodians to ask for testing

Design of a vehicle based system to prevent ozone loss

This project is designed to be completed over a three year period. Overall project goals are: (1) to understand the processes that contribute to stratospheric ozone loss; (2) to determine the best scheme to prevent ozone loss; and (3) to design a vehicle based system to carry out the prevention scheme. The 1993/1994 design objectives included: (1) to review the results of the 1992/1993 design team, including a reevaluation of the key assumptions used; (2) to develop a matrix of baseline vehicle concepts as candidates for the delivery vehicle; and (3) to develop a selection criteria and perform quantitative trade studies to use in the selection of the specific vehicle concept

Combining genotype, phenotype and environment to infer potential candidate genes: An example using the Loblolly pine (Pinus taeda)

Population genomic analyses can be an important tool in understanding local adaptation. Identification of potential adaptive loci in such analyses is usually based on the survey of a large genomic dataset in combination with environmental variables. Phenotypic data are less commonly incorporated into such studies, although combining a genome scan analysis with a phenotypic trait analysis can greatly improve the insights obtained from each analysis individually. Here, we aimed to identify loci potentially involved in adaptation to climate in 283 Loblolly pine (Pinus taeda) samples from throughout the species’ range in the southeastern United States. We analyzed associations between phenotypic, molecular and environmental variables from a published dataset of 3,082 SNP loci and published datasets containing three categories of phenotypic traits (gene expression, metabolites, and whole-plant traits). We found only six SNP loci that displayed potential signals of local adaptation. Five of the six identified SNPs are linked to gene expression traits for lignin development, and one is linked with whole-plant traits. We subsequently compared the six candidate genes with environmental variables and found a high correlation in only three of them (R2 > 0.2). Our study highlights the need for a combination of genotypes, phenotypes, and environmental variables, and for an appropriate sampling scheme and study design, to improve confidence in the identification of potential candidate genes

New Caledonian crows rapidly solve a collaborative problem without cooperative cognition

There is growing comparative evidence that the cognitive bases of cooperation are not unique to humans. However, the selective pressures that lead to the evolution of these mechanisms remain unclear. Here we show that while tool-making New Caledonian crows can produce collaborative behavior, they do not understand the causality of cooperation nor show sensitivity to inequity. Instead, the collaborative behavior produced appears to have been underpinned by the transfer of prior experience. These results suggest that a number of possible selective pressures, including tool manufacture and mobbing behaviours, have not led to the evolution of cooperative cognition in this species. They show that causal cognition can evolve in a domain specific manner-understanding the properties and flexible uses of physical tools does not necessarily enable animals to grasp that a conspecific can be used as a social tool

Immunopotentiation of Trivalent Influenza Vaccine When Given with VAX102, a Recombinant Influenza M2e Vaccine Fused to the TLR5 Ligand Flagellin

BACKGROUND: Currently controversy exists about the immunogenicity of seasonal trivalent influenza vaccine in certain populations, especially the elderly. STF2.4×M2e (VAX102) is a recombinant fusion protein that links four copies of the ectodomain of influenza virus matrix protein 2 (M2e) antigen to Salmonella typhimurium flagellin, a TLR5 ligand. The objectives of this study were to assess the feasibility of giving VAX102 and TIV in combination in an effort to achieve greater immunogenicity and to provide cross-protection. METHODOLOGY/PRINCIPAL FINDINGS: Eighty healthy subjects, 18-49 years old, were enrolled in May and June 2009 in a double-blind, randomized, controlled trial at two clinical sites. Subjects were randomized to receive either TIV + VAX102 or TIV + placebo. Both arms tolerated the vaccines. Pain at the injection site was more severe with TIV + VAX102. Two weeks after immunization the HAI responses to the H1 and H3 antigens of TIV were higher in those that received TIV + VAX102 than in TIV + placebo (309 vs 200 and 269 vs 185, respectively), although statistically non-significant. There was no difference in the HAI of the B antigen. In the TIV + VAX102 arm, the geometric mean M2e antibody concentration was 0.5 µg/ml and 73% seroconverted. CONCLUSIONS/SIGNIFICANCE: The combination of TIV + VAX102 has the potential to increase the immune response to the influenza A components of TIV and to provide M2e immunity which may protect against influenza A strains not contained in seasonal TIV. TRIAL REGISTRATION: ClinicalTrials.gov NCT00921973