A rare case of clostridium difficile infection-associated reactive arthritis

Clostridium difficile is an uncommon cause of reactive arthritis in children. We herein present a rare case of C. difficile infection-associated reactive arthritis (CDIAReA) in a child, who developed severe diarrhea and a knee effusion following a course of oral antibiotic treatment. Our report emphasizes that CDIAReA should be considered in the differential diagnosis of children presenting with acute and painful arthritis that develops in the setting of antibiotic associated diarrhea. © 2018 by Pediatric

Letter to the editor: Pulmonary disease due to rifampin-resistant mycobacterium kansasii in an adolescent

Abstract Not Availabl

Successful treatment of refractory listeria meningitis and bacteremia with trimethoprim-sulfamethoxazole in an immunocompetent child

Listeria monocytogenes is an important cause of life-threatening bacteremia and meningoencephalitis in neonates, pregnant women, the elderly, and immunocompromised individuals. However, it is an uncommon cause of illness in immunocompetent children beyond the neonatal period. Ampicillin with or without an aminoglycoside remains the best treatment for listeriosis. Here, we report a rare case of Listeria meningitis and bacteremia in a 7-month-old immunocompetent girl, which was refractory to ampicillin plus gentamicin treatment and successfully treated by the addition of TMP/SMX

Antimicrobial surgical prophylaxis: Still an issue in paediatrics

Objectives: Antimicrobial prophylaxis (AP) is an important means of reducing surgical site infections. The goal of this study was to evaluate the perioperative AP in paediatric practice and its compliance with surgical prophylaxis guidelines. Methods: A prospective study was conducted at Gazi University Faculty of Medicine, between September 2015 and April 2016. Paediatric patients who underwent surgical procedures were included in the study. Surgical AP was evaluated. Results: During the entire study period, 466 children underwent surgery at our centre; 433 (92.7\%) received antimicrobial prophylaxis. Overall adherence to the guidelines regarding surgical prophylaxis was 22.1\%. The rate of administration of surgical prophylaxis was significantly lower, and the duration was shorter when the surgical procedure was clean (P = 0.002). When the duration of the procedure was longer, the rate of administration of prophylaxis was higher (P = 0.000). The duration of postoperative prophylaxis was longer than recommended in 72.2\% of the patients. In the multivariate analysis, application errors increased with longer surgical time (P = 0.01, OR 2.18, 95\% CI 1.19-4.03). Conclusions: High rates of misapplication of antimicrobial surgical prophylaxis were observed in this study. Awareness and usage of guidelines should be encouraged. The education of clinicians should be supported by studies regarding surgical prophylaxis in children. (C) 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy