Uniform fractional factorial designs

The minimum aberration criterion has been frequently used in the selection of fractional factorial designs with nominal factors. For designs with quantitative factors, however, level permutation of factors could alter their geometrical structures and statistical properties. In this paper uniformity is used to further distinguish fractional factorial designs, besides the minimum aberration criterion. We show that minimum aberration designs have low discrepancies on average. An efficient method for constructing uniform minimum aberration designs is proposed and optimal designs with 27 and 81 runs are obtained for practical use. These designs have good uniformity and are effective for studying quantitative factors.Comment: Published in at http://dx.doi.org/10.1214/12-AOS987 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

A re-visit of the phase-resolved X-ray and \gamma-ray spectra of the Crab pulsar

We use a modified outer gap model to study the multi-frequency phase-resolved spectra of the Crab pulsar. The emissions from both poles contribute to the light curve and the phase-resolved spectra. Using the synchrotron self-Compton mechanism and by considering the incomplete conversion of curvature photons into secondary pairs, the observed phase-averaged spectrum from 100 eV - 10 GeV can be explained very well. The predicted phase-resolved spectra can match the observed data reasonably well, too. We find that the emission from the north pole mainly contributes to Leading Wing 1. The emissions in the remaining phases are mainly dominated by the south pole. The widening of the azimuthal extension of the outer gap explains Trailing Wing 2. The complicated phase-resolved spectra for the phases between the two peaks, namely Trailing Wing 1, Bridge and Leading Wing 2, strongly suggest that there are at least two well-separated emission regions with multiple emission mechanisms, i.e. synchrotron radiation, inverse Compton scattering and curvature radiation. Our best fit results indicate that there may exist some asymmetry between the south and the north poles. Our model predictions can be examined by GLAST.Comment: 35 pages, 13 figures, accepted to publish in Ap

Effects of the complex mass distribution of dark matter halos on weak lensing cluster surveys

Gravitational lensing effects arise from the light ray deflection by all of the mass distribution along the line of sight. It is then expected that weak lensing cluster surveys can provide us true mass-selected cluster samples. With numerical simulations, we analyze the correspondence between peaks in the lensing convergence $\kappa$-map and dark matter halos. Particularly we emphasize the difference between the peak $\kappa$ value expected from a dark matter halo modeled as an isolated and spherical one, which exhibits a one-to-one correspondence with the halo mass at a given redshift, and that of the associated $\kappa$-peak from simulations. For halos with the same expected $\kappa$, their corresponding peak signals in the $\kappa$-map present a wide dispersion. At an angular smoothing scale of $\theta_G=1\hbox{arcmin}$, our study shows that for relatively large clusters, the complex mass distribution of individual clusters is the main reason for the dispersion. The projection effect of uncorrelated structures does not play significant roles. The triaxiality of dark matter halos accounts for a large part of the dispersion, especially for the tail at high $\kappa$ side. Thus lensing-selected clusters are not really mass-selected. (abridged)Comment: ApJ accepte

Coordination motifs and large-scale structural organization in atomic clusters

The structure of nanoclusters is complex to describe due to their noncrystallinity, even though bonding and packing constraints limit the local atomic arrangements to only a few types. A computational scheme is presented to extract coordination motifs from sample atomic configurations. The method is based on a clustering analysis of multipole moments for atoms in the first coodination shell. Its power to capture large-scale structural properties is demonstrated by scanning through the ground state of the Lennard-Jones and C$_{60}$ clusters collected at the Cambridge Cluster Database.Comment: 6 pages, 7 figure

Polarization as a Probe to the Production Mechanisms of Charmonium in πN\pi N Collisions

Measurements of the polarization of \jp produced in pion-nucleus collisions are in disagreement with leading twist QCD prediction where \jp is observed to have negligible polarization whereas theory predicts substantial polarization. We argue that this discrepancy cannot be due to poorly known structure functions nor the relative production rates of \jp and $\chi_J$. The disagreement between theory and experiment suggests important higher twist corrections, as has earlier been surmised from the anomalous non-factorized nuclear $A$-dependence of the \jp cross section.Comment: 8 page

Azimuthal and single spin asymmetry in deep-inelastic lepton-nucleon scattering

We derive a general framework for describing semi-inclusive deep-inelastic lepton-nucleon scattering in terms of the unintegrated parton distributions and other higher twist parton correlations. Such a framework provides a consistent approach to the calculation of inclusive and semi-inclusive cross sections including higher twist effects. As an example, we calculate the azimuthal asymmetries to the order of 1/Q in semi-inclusive process with transversely polarized target. A non-vanishing single-spin asymmetry in the ``triggered inclusive process'' is predicted to be 1/Q suppressed with a part of the coefficient related to a moment of the Sivers function.Comment: 9 pages, 1 figur

Magnetic and the magnetocaloric properties of Ce1-xRxFe2 and Ce(Fe1-xMx)2 compounds

We have studied selected rare earth doped and transition metal doped CeFe2 compounds by examining their structural, magnetic and magneto-thermal properties. With substitution of Ce by 5 and 10% Gd and 10% Ho, the Curie temperature can be tuned to the range of 267-318 K. Localization of Ce 4f electronic state with rare earth substitutions is attributed for the enhancement of Curie temperature. On the other hand, with Ga and Al substitution at the Fe site, system undergoes paramagnetic to ferromagnetic transition and then to an antiferromagnetic phase on cooling. The magnetocaloric effect across the transitions has been studied from both magnetization isotherms and heat capacity data. It is shown that by choosing the appropriate dopant and its concentration, the magnetocaloric effect around room temperature can be tuned.Comment: 13 pages, 6 figures, 2 table

The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant

5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a potent type I interferon (IFN) inducer, was evaluated as a chemotherapeutic agent in mouse cancer models and proved to be well tolerated in human cancer clinical trials. Despite its multiple biological functions, DMXAA has not been fully characterized for the potential application as a vaccine adjuvant. In this report, we show that DMXAA does act as an adjuvant due to its unique property as a soluble innate immune activator. Using OVA as a model antigen, DMXAA was demonstrated to improve on the antigen specific immune responses and induce a preferential Th2 (Type-2) response. The adjuvant effect was directly dependent on the IRF3-mediated production of type-I-interferon, but not IL-33. DMXAA could also enhance the immunogenicity of influenza split vaccine which led to significant increase in protective responses against live influenza virus challenge in mice compared to split vaccine alone. We propose that DMXAA can be used as an adjuvant that targets a specific innate immune signaling pathway via IRF3 for potential applications including vaccines against influenza which requires a high safety profile