10 research outputs found
培養系におけるヒト扁平上皮癌のβデフェンシン遺伝子発現パターンの周囲の細胞による影響
- Author
- Publication venue
- Publication date
- 25/03/2015
- Field of study
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force
- Author
- Abe Ryuzo
- Abe Shinji
- Adachi Tomohiro
- Adachi Yuichi
- Ai Masumi
- Amishima Masaru
- Amiya Saori
- Anan Ryusuke
- Ando Akira
- Anzai Tatsuhiko
- Arai Daisuke
- Arai Ryosuke
- Arai Sawako
- Arakawa Kenichi
- Arimura Ken
- Asakura Takanori
- Asano Koichiro
- Awano Nobuyasu
- Azuma Masanori
- Baba Hiroaki
- Baba Rie
- Baba Tomoya
- Beppu Satoru
- Chiba Shigeru
- Chihara Yusuke
- Chubachi Shotaro
- Edahiro Ryuya
- Egi Moritoki
- Endo Akifumi
- Endo Mayu
- Enomoto Takatoshi
- Eriguchi Yoshihiro
- Fuchimoto Yasuko
- Fujii Kazuhiko
- Fujimoto Nobukazu
- Fujita Kazue
- Fujitani Shigeki
- Fujiwara Akiko
- Fuke Satoshi
- Fukui Takahiro
- Fukui Yasutaka
- Fukunaga Koichi
- Fukuta Tetsuya
- Fukuyama Satoru
- Funatsu Yohei
- Gon Yasuhiro
- Hagihara Masao
- Hagimoto Satoshi
- Hagiwara Eri
- Hagiwara Shigehiro
- Hanada Satoko
- Hara Reina
- Harada Masahiro
- Harada Norihiro
- Harada Sonoko
- Harada Yuko
- Haruta Yuki
- Hase Isano
- Hasegawa Naoki
- Hasegawa Takanori
- Hasegawa Yoshinori
- Hashiguchi Mizuha
- Hashimoto Naozumi
- Hashimoto Satoru
- Hashino Takuya
- Hattori Takeshi
- Hayashi Kentaro
- Hayashi Reina
- Hayashi Shinichi
- Hida Naoya
- Hiki Makoto
- Hirai Yoshihiro
- Hiramatsu Yuji
- Hirano Toshiyuki
- Hiranuma Hisato
- Hirata Haruhiko
- Hirouchi Takatomo
- Honda Takayuki
- Horinouchi Hirohisa
- Hoshino Kota
- Hosoda Chiaki
- Hyugaji Takayoshi
- Ichikado Kazuya
- Ichikawa Masako
- Ichimura Naoya
- Igarashi Akira
- Ihara Shoichi
- Ikemura Shinnosuke
- Imamura Tomonori
- Imoto Seiya
- Inomata Minoru
- Inoue Sumito
- Inoue Takashi
- Inoue Takuya
- Inoue Yoshiaki
- Ishiguro Takashri
- Ishihara Sayoko
- Ishihara Shoichiro
- Ishii Makoto
- Ishii Tomoo
- Ishikawa Motonao
- Ishikura Hiroyasu
- Ishioka Kota
- Isogai Susumu
- Isono Taisuke
- Ito Akihiro
- Ito Fumimaro
- Ito Kazuto
- Ito Satoshi
- Ito Yoko
- Iwagoe Hajime
- Iwamura Hiromu
- Izumi Namiki
- Izumo Takehiro
- Kabata Hiroki
- Kagaya Takashi
- Kagyo Junko
- Kai Hirayasu
- Kamata Hirofumi
- Kamimaki Isamu
- Kamiya Akane
- Kan-o Keiko
- Kanai Masahiro
- Kanai Masayuki
- Kanai Takanori
- Kanaoka Kensuke
- Kanayama Syuji
- Kanda Hidenori
- Kanehiro Arihiko
- Kaneko Yutaro
- Kaneyama Yasunari
- Kasamatsu Yu
- Kashiwada Takeru
- Katayama Kazuhiko
- Katayama Kotoe
- Kato Kazuto
- Kato Yasuhiro
- Kawada Miki
- Kawamura Kodai
- Kawana Akihiko
- Kawana Masatoshi
- Kawashima Hidetoshi
- Kikuchi Ryota
- Kimizuka Yoshifumi
- Kimura Akinori
- Kimura Nozomu
- Kimura Tomoki
- Kimura Tomoyuki
- Kimura Yasuhiro
- Kishi Hiroto
- Kita Toshiyuki
- Kitagawa Yuichiro
- Kitagawa Yuko
- Kitamura Hideya
- Kobayashi Keigo
- Kobayashi Yoichi
- Kodaka Norio
- Kodama Nobuhiro
- Koh Hidefumi
- Kohashi Sumiko
- Koike Ryuji
- Koji Sakamoto
- Kojima Mitsuaki
- Kokuto Hiroyuki
- Komase Yuko
- Komuta Kiyoshi
- Konishi Shunichiro
- Kono Yuta
- Koshida Kiyoshi
- Kozu Yutaka
- Kuge Tomoki
- Kumanogoh Atsushi
- Kuraki Takashige
- Kuramochi Mizuki
- Kurihara Yuko
- Kusaka Yu
- Kuse Naoyuki
- Kuwahara Naota
- Lee Ho
- Maeda Shunsuke
- Maeno Toshitaka
- Makino Shohei
- Makino Yasushi
- Manabe Tadashi
- Maruyama Junichi
- Maruyama Shuhei
- Masaki Katsunori
- Mashimo Shuko
- Masuda Makoto
- Masuzawa Keita
- Matsui Yuma
- Matsumoto Kinnosuke
- Matsumoto Koichiro
- Matsumoto Shuichiro
- Matsumoto Takemasa
- Matsunaga Tomohiro
- Matsuse Hiroto
- Matsushita Yasushi
- Minemura Hiroyuki
- Mitamura Keiko
- Miyagawa Kazuya
- Miyake Takahito
- Miyano Satoru
- Miyawaki Masayoshi
- Miyazaki Masatoshi
- Miyazaki Yasunari
- Miyazaki Yoshimune
- Miyazawa Naoki
- Mochimaru Takao
- Mori Nobuaki
- Morikawa Daiki
- Morisaki Hiroshi
- Morita Atsuho
- Morita Takayoshi
- Motegi Mitsuru
- Murakami Koji
- Murakami Teruaki
- Muranaka Hiroyuki
- Murohashi Kota
- Mutoh Yoshikazu
- Nagai Hideaki
- Nagao Genta
- Nagasaka Tomoki
- Nagasaki Tadao
- Nagasaki Yoji
- Nagata Kaoru
- Naito Tatsuhiko
- Naito Toshio
- Nakachi Ichiro
- Nakada Taka-Aki
- Nakajima Jun
- Nakajima Yukiko
- Nakamori Yasushi
- Nakamura Ai
- Nakamura Kazunori
- Nakamura Morio
- Nakamura Yoshihiko
- Nakano Chihiro
- Nakano Yasushi
- Nakatsumi Hiroki
- Nakayama Sohei
- Namba Shinichi
- Namkoong Ho
- Nanki Kosaku
- Nannya Yasuhito
- Narita Atsuya
- Narumoto Osamu
- Niitsu Takayuki
- Nikaido Takefumi
- Nishi Koichi
- Nishida Takashi
- Nishikawa Masanori
- Nishimura Tomoyasu
- Nishio Kazumi
- Nishitsuji Masaru
- Nishiyama Kei
- Nishiyama Kenta
- Niwa Kazuki
- Noda Yoshimi
- Noguchi Yoichiro
- Nukaga Shigenari
- Ochi Junichi
- Odani Toshio
- Odate Mitsuru
- Ogata Hideo
- Ogata Tomouki
- Ogawa Aki
- Ogawa Seishi
- Ogawa Shinichi
- Oguma Tsuyoshi
- Ogura Shinji
- Ogura Takashi
- Ogura Takayuki
- Ohba Takehiko
- Ohira Yoshiyuki
- Ohta Kazuhide
- Ohta Ken
- Ohta Shin
- Okabayashi Hiroko
- Okada Takenori
- Okada Yukinori
- Okamori Satoshi
- Okamoto Masaki
- Omae Yosuke
- Omote Norihito
- Ono Akihiro
- Ono Hiroshi
- Ono Yoshinao
- Onoi Keisuke
- Ooshima Nobuharu
- Osawa Takeshi
- Oshima Taku
- Oshio Takeshi
- Ota Sho
- Oyama Baku
- Oyamada Yoshitaka
- Ozaki Shinji
- Sado Reiko
- Sado Toshikatsu
- Sagara Hironori
- Sageshima Hisako
- Saiki Ryunosuke
- Saito Fukuki
- Saito Fumitake
- Saito Hiroshi
- Saito Ryuichi
- Saito Yoshinobu
- Sakagami Satoru
- Sakurai Toshihiro
- Sandhu Yuuki
- Sano Hirohito
- Sano Tomoya
- Sasa Noah
- Sasaki Junichi
- Sasaki Kana
- Sasano Hajime
- Sassa Chihiro Tani
- Sato Masamichi
- Sato Ryuichi
- Sato Tomonori
- Sato Toshiro
- Sato Yoko
- Sato Yuki
- Satomi Ryosuke
- Seike Masahiro
- Sekikawa Yoshiyuki
- Shibata Shun
- Shibata Yoko
- Shibusawa Takayuki
- Shichinohe Yasuo
- Shimada Hisato
- Shimada Tadanaga
- Shimizu Eigo
- Shimizu Tetsuo
- Shimo Masatoshi
- Shimoda Masafumi
- Shinoki Masato
- Shinozuka Jun
- Shinozuka Keisuke
- Shiomi Tetsuya
- Shirai Yuya
- Shiroyama Takayuki
- Shoko Tomohisa
- Sonehara Kyuto
- Sonobe Kazunari
- Suematsu Ryohei
- Sueyoshi Atsushi
- Sugimoto Hideyasu
- Sugiura Hisatoshi
- Suzuki Junya
- Suzuki Shoji
- Suzuki Yusuke
- Tada Ai
- Tagaya Etsuko
- Takada Minoru
- Takagi Haruhi
- Takahashi Hidenori
- Takahashi Hiroshi
- Takahashi Kazuhisa
- Takahashi Kenichiro
- Takahashi Kunihiko
- Takahashi Mai
- Takahashi Saeko
- Takahashi Takeshi
- Takaku Yotaro
- Takano Kenji
- Takano Tomomi
- Takaoka Hatsuyo
- Takata Tohru
- Takayanagi Noboru
- Takeda Yoshito
- Takei Reoto
- Takeuchi Mayumi
- Taki Reiko
- Takita Mumon
- Takoi Hiroyuki
- Tanaka Akihiko
- Tanaka Hiromu
- Tanaka Toru
- Tanaka Yoshiaki
- Tani Mayuko
- Tanino Yoshinori
- Tateishi Tomoya
- Tateno Hiroki
- Terai Hideki
- Terashima Mariko
- Togashi Yuki
- Tohda Shuji
- Tokunaga Katsushi
- Tokunaga Yoshihisa
- Tominaga Yoshiteru
- Tomono Kazunori
- Tone Mari
- Tsuburai Takahiro
- Tsuchida Tomoya
- Uchida Sho
- Uchida Tomoyuki
- Uchimura Yuji
- Ueda Ken
- Ueda Soichiro
- Ueda Suguru
- Ueda Tetsuya
- Ueno Takafumi
- Umeda Akira
- Uno Shunsuke
- Utsugi Mitsuyoshi
- Uwamino Yoshifumi
- Wada Daiki
- Wada Sae
- Wakabayashi Aya
- Wakahara Keiko
- Wang Qingbo S.
- Watanabe Chie
- Watanabe Hiroki
- Watanabe Hiroko
- Watanabe Kazuyoshi
- Watanabe Masafumi
- Yagi Kazuma
- Yamada Mitsuhiro
- Yamada Yuichiro
- Yamagata Kunihiro
- Yamaguchi Yuta
- Yamamoto Kenichi
- Yamamoto Makoto
- Yamamoto Masaomi
- Yamamoto Yuji
- Yamano Yasuhiko
- Yamasaki Masaki
- Yamashita Tatsuya
- Yasui Yoshinori
- Yatomi Masakiyo
- Yokote Koutaro
- Yoneda Midori
- Yonekawa Akiko
- Yoshida Eriko
- Yoshida Kosuke
- Yoshida Shozo
- Yoshida Shuichi
- Yoshida Toru
- Yoshifuji Ayumi
- Yoshihara Tomoyuki
- Yoshiya Kazuhisa
- Yoshiyama Takashi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
「コロナ制圧タスクフォース」COVID-19患者由来の血液細胞における遺伝子発現の網羅的解析 --重症度に応じた遺伝子発現の変化には、ヒトゲノム配列の個人差が影響する--. 京都大学プレスリリース. 2022-08-23.Coronavirus disease 2019 (COVID-19) is a recently-emerged infectious disease that has caused millions of deaths, where comprehensive understanding of disease mechanisms is still unestablished. In particular, studies of gene expression dynamics and regulation landscape in COVID-19 infected individuals are limited. Here, we report on a thorough analysis of whole blood RNA-seq data from 465 genotyped samples from the Japan COVID-19 Task Force, including 359 severe and 106 non-severe COVID-19 cases. We discover 1169 putative causal expression quantitative trait loci (eQTLs) including 34 possible colocalizations with biobank fine-mapping results of hematopoietic traits in a Japanese population, 1549 putative causal splice QTLs (sQTLs; e.g. two independent sQTLs at TOR1AIP1), as well as biologically interpretable trans-eQTL examples (e.g., REST and STING1), all fine-mapped at single variant resolution. We perform differential gene expression analysis to elucidate 198 genes with increased expression in severe COVID-19 cases and enriched for innate immune-related functions. Finally, we evaluate the limited but non-zero effect of COVID-19 phenotype on eQTL discovery, and highlight the presence of COVID-19 severity-interaction eQTLs (ieQTLs; e.g., CLEC4C and MYBL2). Our study provides a comprehensive catalog of whole blood regulatory variants in Japanese, as well as a reference for transcriptional landscapes in response to COVID-19 infection
DOCK2 is involved in the host genetics and biology of severe COVID-19
- Author
- Abe Ryuzo
- Abe Shinji
- Adachi Tomohiro
- Adachi Yuichi
- Ai Masumi
- Amishima Masaru
- Amiya Saori
- Anan Ryusuke
- Ando Akira
- Anzai Tatsuhiko
- Aoki Ryousuke
- Arai Daisuke
- Arai Ryosuke
- Arai Sawako
- Arakawa Kenichi
- Arimura Ken
- Asai Satoshi
- Asakura Takanori
- Asano Koichiro
- Awano Nobuyasu
- Azekawa Shuhei
- Azuma Masanori
- Baba Hiroaki
- Baba Rie
- Baba Tomoya
- Beppu Satoru
- Chiba Shigeru
- Chihara Yusuke
- Chubachi Shotaro
- Edahiro Ryuya
- Egi Moritoki
- Eguchi Hirotaka
- Endo Akifumi
- Endo Mayu
- Enomoto Takatoshi
- Eriguchi Yoshihiro
- Fuchimoto Yasuko
- Fujii Kazuhiko
- Fujimoto Nobukazu
- Fujita Kazue
- Fujitani Shigeki
- Fujiwara Akiko
- Fuke Satoshi
- Fukui Takahiro
- Fukui Yasutaka
- Fukui Yoshinori
- Fukunaga Koichi
- Fukushima Munehisa
- Fukusumi Takahito
- Fukuta Tetsuya
- Fukuyama Satoru
- Funatsu Yohei
- Furukawa Yoichi
- Gon Yasuhiro
- Hagihara Masao
- Hagimoto Satoshi
- Hagiwara Eri
- Hagiwara Shigehiro
- Hamamoto Junko
- Hanada Satoko
- Hara Reina
- Harada Masahiro
- Harada Norihiro
- Harada Sonoko
- Harada Yuko
- Haruta Yuki
- Hase Isano
- Hasegawa Naoki
- Hasegawa Takanori
- Hasegawa Yoshinori
- Hashiguchi Mizuha
- Hashimoto Naozumi
- Hashimoto Satoru
- Hashino Takuya
- Hattori Takeshi
- Hayashi Hiroyuki
- Hayashi Kentaro
- Hayashi Reina
- Hayashi Shinichi
- Hida Naoya
- Higashiyama Masahiko
- Hiki Makoto
- Hirai Yoshihiro
- Hiramatsu Yuji
- Hirano Toshiyuki
- Hiranuma Hisato
- Hirata Haruhiko
- Hirouchi Takatomo
- Hizawa Nobuyuki
- Honda Takayuki
- Horinouchi Hirohisa
- Hoshino Kota
- Hosoda Chiaki
- Hyugaji Takayoshi
- Ichikado Kazuya
- Ichimura Naoya
- Igarashi Akira
- Ihara Shoichi
- Ikemura Shinnosuke
- Imai Takao
- Imamura Tomonori
- Imoto Seiya
- Inohara Hidenori
- Inomata Minoru
- Inoue Sumito
- Inoue Takashi
- Inoue Takuya
- Inoue Yoshiaki
- Ishiguro Takashi
- Ishihara Rino
- Ishihara Sayoko
- Ishihara Shoichiro
- Ishii Makoto
- Ishii Tomoo
- Ishikawa Motonao
- Ishikura Hiroyasu
- Ishioka Kota
- Isogai Susumu
- Isono Taisuke
- Ito Akihiro
- Ito Fumimaro
- Ito Kazuto
- Ito Satoshi
- Ito Yoko
- Iwagoe Hajime
- Iwamura Hiromu
- Izumi Namiki
- Izumo Takehiro
- Kabata Hiroki
- Kagaya Takashi
- Kagyo Junko
- Kai Hirayasu
- Kamata Hirofumi
- Kamatani Yoichiro
- Kamimaki Isamu
- Kamiya Akane
- Kan-o Keiko
- Kanai Masahiro
- Kanai Masayuki
- Kanai Takanori
- Kanaoka Kensuke
- Kanayama Syuji
- Kanda Hidenori
- Kanehiro Arihiko
- Kaneko Yutaro
- Kaneyama Yasunari
- Kasamatsu Yu
- Kashiwada Takeru
- Katayama Kazuhiko
- Katayama Kotoe
- Kato Kazuto
- Kato Yasuhiro
- Kawabata Shuhei
- Kawada Miki
- Kawamura Kodai
- Kawamura Yusuke
- Kawana Akihiko
- Kawana Masatoshi
- Kawashima Hidetoshi
- Kijima Noriyuki
- Kikuchi Ryota
- Kimizuka Yoshifumi
- Kimura Akinori
- Kimura Nozomu
- Kimura Tomoki
- Kimura Tomoyuki
- Kimura Yasuhiro
- Kishi Hiroto
- Kishikawa Toshihiro
- Kishima Haruhiko
- Kita Toshiyuki
- Kitagawa Yuichiro
- Kitagawa Yuko
- Kitamura Hideya
- Kobayashi Keigo
- Kobayashi Yoichi
- Kodaka Norio
- Kodama Nobuhiro
- Koh Hidefumi
- Kohashi Sumiko
- Koike Ryuji
- Koji Sakamoto
- Kojima Mitsuaki
- Kokuto Hiroyuki
- Komase Yuko
- Komuta Kiyoshi
- Konishi Shunichiro
- Kono Yuta
- Koretsune Yukihiro
- Koshida Kiyoshi
- Kozu Yutaka
- Kuge Tomoki
- Kumanogoh Atsushi
- Kuraki Takashige
- Kuramochi Mizuki
- Kurihara Yuko
- Kusaka Yu
- Kuse Naoyuki
- Kuwahara Naota
- Lee Ho
- Liu Yu-Chen
- Maeda Shunsuke
- Maeda Yuichi
- Maeno Toshitaka
- Makino Shohei
- Makino Yasushi
- Manabe Tadashi
- Maruyama Junichi
- Maruyama Shuhei
- Masaki Katsunori
- Mashimo Shuko
- Masuda Makoto
- Masumoto Akihide
- Masuzawa Keita
- Matsubara Yuta
- Matsuda Fumihiko
- Matsuda Koichi
- Matsui Yuma
- Matsumoto Kinnosuke
- Matsumoto Koichiro
- Matsumoto Shuichiro
- Matsumoto Takemasa
- Matsunaga Tomohiro
- Matsuo Hirotaka
- Matsuse Hiroto
- Matsushita Yasushi
- Mikami Yohei
- Minami Shiro
- Minemura Hiroyuki
- Mitamura Keiko
- Miyagawa Kazuya
- Miyake Takahito
- Miyano Satoru
- Miyawaki Masayoshi
- Miyawaki Satoru
- Miyazaki Masatoshi
- Miyazaki Yasunari
- Miyazaki Yoshimune
- Miyazawa Naoki
- Mochimaru Takao
- Mori Nobuaki
- Morikawa Daiki
- Morisaki Hiroshi
- Morisaki Takayuki
- Morita Atsuho
- Morita Takayoshi
- Motegi Mitsuru
- Motooka Daisuke
- Murakami Koji
- Murakami Teruaki
- Murakami Yoshinori
- Muranaka Hiroyuki
- Murayama Shigeo
- Murohashi Kota
- Muto Kaori
- Mutoh Yoshikazu
- Nagai Akiko
- Nagai Hideaki
- Nagao Genta
- Nagasaka Tomoki
- Nagasaki Tadao
- Nagasaki Yoji
- Nagata Kaoru
- Nagayama Satoshi
- Naito Tatsuhiko
- Naito Toshio
- Naito Yoko
- Nakachi Ichiro
- Nakada Taka-Aki
- Nakajima Jun
- Nakajima Yukiko
- Nakamori Yasushi
- Nakamura Ai
- Nakamura Kazunori
- Nakamura Morio
- Nakamura Yoshihiko
- Nakano Chihiro
- Nakano Yasushi
- Nakatsumi Hiroki
- Nakayama Akiyoshi
- Nakayama Sohei
- Namba Shinichi
- Namkoong Ho
- Nanki Kosaku
- Nannya Yasuhito
- Narita Atsuya
- Narumoto Osamu
- Nii Takuro
- Niitsu Takayuki
- Nikaido Takefumi
- Nishi Koichi
- Nishida Takashi
- Nishihara Hiroshi
- Nishikawa Masanori
- Nishimura Tomoyasu
- Nishio Kazumi
- Nishitsuji Masaru
- Nishiyama Kei
- Nishiyama Kenta
- Niwa Kazuki
- Noda Yoshimi
- Noguchi Yoichiro
- Nukaga Shigenari
- Obara Wataru
- Obata Daisuke
- Ochi Junichi
- Odani Toshio
- Odate Mitsuru
- Ogata Hideo
- Ogata Tomouki
- Ogawa Aki
- Ogawa Seishi
- Ogawa Shinichi
- Oguma Tsuyoshi
- Ogura Shinji
- Ogura Takashi
- Ogura Takayuki
- Ohba Takehiko
- Ohira Yoshiyuki
- Ohta Kazuhide
- Ohta Ken
- Ohta Shin
- Okabayashi Hiroko
- Okada Takenori
- Okada Yukinori
- Okamori Satoshi
- Okamoto Masaki
- Okudela Koji
- Okuzaki Daisuke
- Omae Yosuke
- Omote Norihito
- Ono Akihiro
- Ono Hiroshi
- Ono Yoshinao
- Onoi Keisuke
- Ooshima Nobuharu
- Osawa Takeshi
- Oshima Taku
- Oshio Takeshi
- Ota Sho
- Oyama Baku
- Oyamada Yoshitaka
- Ozaki Shinji
- Sado Reiko
- Sado Toshikatsu
- Sagara Hironori
- Sageshima Hisako
- Saiki Ryunosuke
- Saito Fukuki
- Saito Fumitake
- Saito Hiroshi
- Saito Ryuichi
- Saito Yoshinobu
- Sakagami Satoru
- Sakakibara Shuhei
- Sakurai Toshihiro
- Sano Hirohito
- Sano Tomoya
- Sasa Noah
- Sasaki Junichi
- Sasaki Kana
- Sasano Hajime
- Sasano Hitoshi
- Sassa Chihiro Tani
- Sato Masamichi
- Sato Ryuichi
- Sato Tomonori
- Sato Toshiro
- Sato Yoko
- Sato Yuki
- Satomi Ryosuke
- Seike Masahiro
- Sekikawa Yoshiyuki
- Shibata Shun
- Shibata Yoko
- Shibusawa Takayuki
- Shichinohe Yasuo
- Shimada Hisato
- Shimada Tadanaga
- Shimizu Eigo
- Shimizu Tetsuo
- Shimo Masatoshi
- Shimoda Masafumi
- Shinoki Masato
- Shinozuka Jun
- Shinozuka Keisuke
- Shiomi Tetsuya
- Shirai Yuya
- Shiroyama Takayuki
- Shoko Tomohisa
- Sinozaki Nobuaki
- Sonehara Kyuto
- Sonobe Kazunari
- Suematsu Ryohei
- Sueyoshi Atsushi
- Sugihara Fuminori
- Sugimoto Hideyasu
- Sugiura Hisatoshi
- Suzuki Junya
- Suzuki Ken
- Suzuki Motoyuki
- Suzuki Shoji
- Suzuki Takao
- Suzuki Yusuke
- Tachikawa Natsuo
- Tada Ai
- Tagaya Etsuko
- Takada Minoru
- Takagaki Masatoshi
- Takagi Haruhi
- Takahashi Hidenori
- Takahashi Hiroshi
- Takahashi Kazuhisa
- Takahashi Kenichiro
- Takahashi Kunihiko
- Takahashi Mai
- Takahashi Meiko
- Takahashi Saeko
- Takahashi Takeshi
- Takahashi Yasuo
- Takaku Yotaro
- Takano Kenji
- Takano Tomomi
- Takaoka Hatsuyo
- Takata Tohru
- Takayanagi Noboru
- Takeda Yoshito
- Takei Reoto
- Takemoto Norihiko
- Takeuchi Mayumi
- Taki Reiko
- Takita Mumon
- Takoi Hiroyuki
- Takuwa Ayako
- Tanaka Akihiko
- Tanaka Hiromu
- Tanaka Toru
- Tanaka Yoshiaki
- Tani Mayuko
- Tanino Yoshinori
- Tateishi Tomoya
- Tateno Hiroki
- Terai Hideki
- Terashima Mariko
- Togashi Yuki
- Tohda Shuji
- Tokunaga Katsushi
- Tokunaga Yoshihisa
- Tominaga Yoshiteru
- Tomono Kazunori
- Tone Mari
- Tsuburai Takahiro
- Tsuchida Tomoya
- Uchida Sho
- Uchida Tomoyuki
- Uchimura Yuji
- Ueda Ken
- Ueda Soichiro
- Ueda Suguru
- Ueda Tetsuya
- Ueno Takafumi
- Ueno Yuya
- Umeda Akira
- Uno Shunsuke
- Utsugi Mitsuyoshi
- Uwamino Yoshifumi
- Wada Daiki
- Wada Sae
- Wakabayashi Aya
- Wakahara Keiko
- Wang Qingbo S.
- Watanabe Chie
- Watanabe Hiroki
- Watanabe Hiroko
- Watanabe Kazuyoshi
- Watanabe Masafumi
- Wing James B.
- Yagi Kazuma
- Yamada Mitsuhiro
- Yamada Shuhei
- Yamada Yuichiro
- Yamagata Kunihiro
- Yamaguchi Hiroki
- Yamaguchi Yuta
- Yamaji Ken
- Yamamoto Kenichi
- Yamamoto Makoto
- Yamamoto Masaomi
- Yamamoto Yuji
- Yamanashi Yuji
- Yamano Yasuhiko
- Yamasaki Masaki
- Yamashita Tatsuya
- Yanagita Emmy
- Yasui Yoshinori
- Yatomi Masakiyo
- Yokote Koutaro
- Yoneda Midori
- Yonekawa Akiko
- Yoshida Eriko
- Yoshida Kosuke
- Yoshida Shozo
- Yoshida Shuichi
- Yoshida Toru
- Yoshifuji Ayumi
- Yoshihara Tomoyuki
- Yoshimori Kozo
- Yoshimura Yukihiro
- Yoshiya Kazuhisa
- Yoshiyama Takashi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
「コロナ制圧タスクフォース」COVID-19疾患感受性遺伝子DOCK2の重症化機序を解明 --アジア最大のバイオレポジトリーでCOVID-19の治療標的を発見--. 京都大学プレスリリース. 2022-08-10.Identifying the host genetic factors underlying severe COVID-19 is an emerging challenge. Here we conducted a genome-wide association study (GWAS) involving 2, 393 cases of COVID-19 in a cohort of Japanese individuals collected during the initial waves of the pandemic, with 3, 289 unaffected controls. We identified a variant on chromosome 5 at 5q35 (rs60200309-A), close to the dedicator of cytokinesis 2 gene (DOCK2), which was associated with severe COVID-19 in patients less than 65 years of age. This risk allele was prevalent in East Asian individuals but rare in Europeans, highlighting the value of genome-wide association studies in non-European populations. RNA-sequencing analysis of 473 bulk peripheral blood samples identified decreased expression of DOCK2 associated with the risk allele in these younger patients. DOCK2 expression was suppressed in patients with severe cases of COVID-19. Single-cell RNA-sequencing analysis (n = 61 individuals) identified cell-type-specific downregulation of DOCK2 and a COVID-19-specific decreasing effect of the risk allele on DOCK2 expression in non-classical monocytes. Immunohistochemistry of lung specimens from patients with severe COVID-19 pneumonia showed suppressed DOCK2 expression. Moreover, inhibition of DOCK2 function with CPYPP increased the severity of pneumonia in a Syrian hamster model of SARS-CoV-2 infection, characterized by weight loss, lung oedema, enhanced viral loads, impaired macrophage recruitment and dysregulated type I interferon responses. We conclude that DOCK2 has an important role in the host immune response to SARS-CoV-2 infection and the development of severe COVID-19, and could be further explored as a potential biomarker and/or therapeutic target
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
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- Cheng Jan-Fang
- Cheng Zhihua
- Chertkov Olga
- Cheshatsang Yama
- Chi Cheng
- Chi Han C.
- Chillingworth Neil
- Chin Sylvia
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- Chissoe Stephanie
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- Lowenstein Michael G.
- Lowry Stephen
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- Lu Lingfeng
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- Lucier Raymond L.
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- Madabhushi Ramki
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- Nwokenkwo Stanley
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- Sonnhammer Erik
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- Stallings Raymond I.
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- Subramanian Sandhya
- Sudbrak Ralf
- Sugnet Charles W.
- Sulston John
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- Sun Min
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- Sun Yu
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- Sutherland Robert D.
- Sutton Angelica E.
- Svatek Amanda F.
- Svetz Jessica
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- Tian Chaoguang
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- Tice Hope
- Tighe Damon
- Tin-Wollam Aye M.
- Tinsley Emma
- Tochigi Miwako
- Togashi Naoko
- Tomizawa Iori
- Tomlinson Chad
- Tong Jingli
- Topham Kerri
- Torcaso Bill
- Torney David C.
- Totoki Yasushi
- Towey Sarah
- Toyoda Atsushi
- Tracey Alan
- Tran Ly Thanh
- Tran-Gyamfi Mary
- Trani Lee
- Trankiem Margie
- Trask Barbara J.
- Travers Johnathan
- Trejos Zulma Y.
- Treuhaft Marianne
- Trevino Brenda Kaye
- Tromans Anthony
- Trong Stephan
- Trumbower Heather
- Tsai Ming
- Tsamla Tsamla
- Tsolas Jason
- Tsomo Nawang
- Tsujimoto Susan
- Tsukamoto Yumi
- Tsuruoka Hiromi
- Tsuzuki Rina
- Tu Yuefeng
- Tu Yuefeng
- Tubby Ben
- Tufarelli Cristina
- Turner Heidi
- Turney Kathryn
- Tynan Katherine
- Ueland Stephanie
- Ueng Samantha
- Ukegbu Ogechi Nkemdirim
- Ulanovsky Levy E.
- Un Chun
- Ung Quyen
- Upson Darren
- Urban Jeremy B.
- Ureta-Vidal Abel
- Ureta-Vidal Abel
- Usmani Kamran
- Ustaszewska Anna
- Uyama Nozomi
- Valas Ruben E.
- Valdez Michelle
- Valle Duane
- Valles Yvonne
- Van Brunt Andrew
- Van Dilla Marvin
- Van Helmond Zoe
- Van Luchene Ryan
- Vardanian Zachary
- Vargas Michelle
- Vargo Charles E.
- Vartanian Steffan
- Vasquez Lydia I.
- Vassiliev Helen
- Vastrik Imre
- Vaudin Mark
- Veil Rose
- Veklerov Eugene
- Velasco Nelson
- Velasquez Lisa
- Venkataranan Vijay
- Vera Virginia A.
- Verduzco Daniel
- Vergez Lisa
- Vico Virginie
- Viknaraja Ramya
- Villasana Donna M.
- Vine Wendy
- Viswanathan Vijay
- Vo Andy
- Vo Nu
- Voak Paul
- Vollenhoven David
- Wada Hiromi
- Wagner Mark
- Wagner-McPherson Caryn
- Waldron Lenee
- Waligorski Jason E.
- Walker Davian L.
- Walker Keya
- Walker Sarah
- Wall Melanie
- Wall Randy E.
- Wallace John
- Wallis Justine
- Wallis Michelle
- Walsh Jennifer
- Walsham Natalie
- Wan Ma
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- Wang Ying
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- Wangdi Tsering
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- Warren Graham
- Warren James T.
- Warry Georgina
- Watanabe Hidemi
- Watanabe Saki
- Waterston Robert H.
- Watson Andy
- Watt Nicola
- Webb Anthony
- Webb Jeannette
- Webber Caleb
- Weber Ryan J.
- Wehri Edward
- Wei Shulin
- Wei Xuehong
- Weidenbach Richard
- Weinstock George
- Weinstock Keith
- Weir John
- Weissenbach Jean
- Wells Alan
- Wells Sarah
- Welton Robert
- Wen Gaiping
- Wendi Mike
- Weng Li
- Wenning Sarah
- Wentz Sara
- Werler Daniela
- Wesley Mary Melissa
- West Paul
- West Tony
- Wetterstrand Kris
- Wheatley Angela
- Wheatley Carl
- Wheeler David A.
- Wheeler Gideon
- Wheeler Jeremy
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- White Adam
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- White P. Scott
- White Scott P.
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- Whitehead Sally
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- Whittaker Charles
- Whittaker Pamela
- Wickremasinghe Manosha I.
- Widaa Sara
- Wiegel Sarah
- Wild Anna
- Wilkinson Jane
- Wilkinson Jane
- Wilkinson Paul
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- Williamson Helen
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- Wollard Jessica
- Womack Andrew W.
- Wong Benjamin
- Wong Gane K-S
- Wood Diane
- Wood Emma
- Wood Joe
- Wooden Hailey S.
- Wooden Steven H.
- Woodeson Sharon
- Woodfine Kathryn
- Woodmansey Rebecca
- Woods Eric
- Woodwark Cara
- Wooster Richard
- Worley Kim Carlyle
- Woyke Tanja
- Wray Matthew
- Wray Paul
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- Wright Debbie
- Wright Kathrine
- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
- Wu Jiaqian
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- Wu Qingfa
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- Wu Xiaojing
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- Wycoff-Montenegro Melissa
- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
- Xie Fei
- Xie Gary
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- Xiong Hui
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- Xu Jing
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- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
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- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
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- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
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- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
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- Zhang Jiuchun
- Zhang Jiuchun
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- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
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- Zhang Ruhua
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- Zhang Xiuqing
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- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Surrounding Cells Affect Gene Expression Pattern of Human Beta-defensins in Squamous Cell Carcinoma In Vitro
- Author
- Publication venue
- Publication date
- Field of study
Live imaging of transforming growth factor-β activated kinase 1 activation in Lewis lung carcinoma 3LL cells implanted into syngeneic mice and treated with polyinosinic: Polycytidylic acid
- Publication venue
- 'Wiley'
- Publication date
- 01/05/2016
- Field of study
Transforming growth factor-β activated kinase 1 (TAK1) has been shown to play a crucial role in cell death, differentiation, and inflammation. Here, we live-imaged robust TAK1 activation in Lewis lung carcinoma 3LL cells implanted into the s.c. tissue of syngeneic C57BL/6 mice and treated with polyinosinic:polycytidylic acid (PolyI:C). First, we developed and characterized a Förster resonance energy transfer-based biosensor for TAK1 activity. The TAK1 biosensor, named Eevee-TAK1, responded to stress-inducing reagents such as anisomycin, tumor necrosis factor-α, and interleukin1-β. The anisomycin-induced increase in Förster resonance energy transfer was abolished by the TAK1 inhibitor (5z)-7-oxozeaenol. Activity of TAK1 in 3LL cells was markedly increased by PolyI:C in the presence of macrophages. 3LL cells expressing Eevee-TAK1 were implanted into mice and observed through imaging window by two-photon excitation microscopy. During the growth of tumor, the 3LL cells at the periphery of the tumor showed higher TAK1 activity than the 3LL cells located at the center of the tumor, suggesting that cells at the periphery of the tumor mass were under stronger stress. Injection of PolyI:C, which is known to induce regression of the implanted tumors, induced marked and homogenous TAK1 activation within the tumor tissues. The effect of PolyI:C faded within 4 days. These observations suggest that Eevee-TAK1 is a versatile tool to monitor cellular stress in cancer tissues. The TAK1 FRET biosensor enables visualization of the stress response in vivo
Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways
- Author
- Publication venue
- Publication date
- 05/10/2006
- Field of study
The activation of tumor suppressor p53 induces apoptosis or cell cycle arrest depending on the state and type of cell, but it is not fully understood how these different responses are regulated. Here, we show that Puma and Noxa, the well-known p53-inducible proapoptotic members of the Bcl-2 family, differentially participate in dual pathways of the induction of apoptosis. In normal cells, Puma but not Noxa induces mitochondrial outer membrane permeabilization (MOMP), and this function is mediated in part by a pathway that involves calcium release from the endoplasmic reticulum (ER) and the subsequent caspase activation. However, upon E1A oncoprotein expression, cells also become susceptible to MOMP induction by Noxa, owing to their sensitization to the ER-independent pathway. These findings offer a new insight into differential cellular responses induced by p53, and may have therapeutic implications in cancer
RalB directly triggers invasion downstream Ras by mobilizing the Wave complex
- Author
- Publication venue
- 'eLife Sciences Publications, Ltd'
- Publication date
- 01/01/2018
- Field of study
International audienceThe two Ral GTPases, RalA and RalB, have crucial roles downstream Ras oncoproteins in human cancers; in particular, RalB is involved in invasion and metastasis. However, therapies targeting Ral signalling are not available yet. By a novel optogenetic approach, we found that light-controlled activation of Ral at plasma-membrane promotes the recruitment of the Wave Regulatory Complex (WRC) via its effector exocyst, with consequent induction of protrusions and invasion. We show that active Ras signals to RalB via two RalGEFs (Guanine nucleotide Exchange Factors), RGL1 and RGL2, to foster invasiveness; RalB contribution appears to be more important than that of MAPK and PI3K pathways. Moreover, on the clinical side, we uncovered a potential role of RalB in human breast cancers by determining that RalB expression at protein level increases in a manner consistent with progression toward metastasis. This work highlights the Ras-RGL1/2-RalB-exocyst-WRC axis as appealing target for novel anticancer strategies
Empagliflozin in Patients with Chronic Kidney Disease
- Author
- Aamir Navivala
- Abdulwahab Arbi
- Abegail Hernandez Pena
- Abraham Hanburry
- Adedolapo Adeleke
- Adeera Levin
- Adil Hazara
- Adline Ghazi
- Agnes Masengu
- Ahmad Tuffaha
- Ahmed Awad
- Ahmed Ghanem
- Ai Fukasawa
- Aik Kheng Lee
- Aiko Terakawa
- Aiko Tomita
- Aiko Yamada
- Ailsa Geddes
- Airi Sato
- Akane Katanosaka
- Akane Yamamoto
- Akihiro Fujimoto
- Akihiro Katayama
- Akihito Tanaka
- Akiko Fujita
- Akiko Hashimoto
- Akiko Ishiguro
- Akiko Omata
- Akimasa Asai
- Akinwande Akinfolarin
- Akio Kanazawa
- Akiyo Nishiyama
- Akiyo Tanabe
- Alastair Rankin
- Alastair Woodman
- Albert Hing
- Albert Power
- Alberto Rosati
- Aldo P Maggioni
- Aldo Peixoto
- Aleksandra Murawska
- Alessandro D'Amelio
- Alex Aguilera
- Alex Baxter
- Alex Howson
- Alexa Wonnacott
- Alexander Hadley
- Alexander Hodakowski
- Alexander Paliege
- Alexis Africano
- Alexis Stevenson
- Alfio Giuffrida
- Alfred K Cheung
- Alia Hasan
- Alia Zubaidah Bahtar
- Alice Aitken
- Alice Guerini
- Aliseiya Garza
- Alison Cowley
- Alison Jenkins
- Alison Timadjer
- Allen Young
- Allison Leslie
- Amalia Caamano
- Amanda Aliu
- Amanda Axler
- Amanda Davis
- Amanda Scott
- Amanda Tyler
- Amar Ali
- Amber Avery
- Amber Hurst
- Amelia Te
- Ami Inamori
- Amin Oomatia
- Amir Kazory
- Amret Hawfield
- Amritanshu Pandey
- Amy Hudson
- Amy Hunter
- Amy Mottl
- Ana Moncada
- Anand Srivastava
- Anastassiya Reisler
- Anca Gherman
- Andre Valleteau
- Andrea Lorimer
- Andrea Schwab
- Andrea Webster
- Andrea Wilson
- Andreas Schneider
- Andrew Breach
- Andrew Connor
- Andrew Frankel
- Andrew Gordon
- Andrew Lewington
- Andrew Shepherd
- Andrew Steele
- Andy Burke
- Andy Measor
- Angela Bergner
- Angela Chamberlain
- Angela Field
- Angela Moon
- Angeline Mbuyisa
- Angharad Williams
- Anil George
- Anita Hepditch
- Anita Kamarzarian
- Anja Knoppe
- Anju Oommen
- Anke Torp
- Ankit Mehta
- Ann Bennett
- Ann Cooper
- Ann Vasseur
- Anna Brewer
- Anna Liew
- Anna Postal
- Anna Romo
- Anna Sampson
- Annalisa Aloisi
- Anne Froment
- Anne Grace
- Anne Schreiber
- Anne-Marie Beneat
- Annegret Fleischer
- Annette Kraemer-Guth
- Annie Saillant
- Annika Küpper
- Anoushka Bhatt
- Anthony Lambert
- Anthony Torres
- Anthoula Apostolidi
- Antonia Schuster
- Antonio Cardone
- Aoife O'Sullivan
- Aparna Padiyar
- Arash Rashidi
- Archie Maskill
- Arelis Madera
- Arif Khwaja
- Arihiro Kiyosue
- Asako Takesada
- Ashlee Morris
- Ashleigh Wheeler
- Ashley Lawson
- Ashwathy Varughese
- Ashwini Gore
- Asma Sabarai
- Astrid Maselli
- Atsuko Nakatsuka
- Atsuyuki Tokuyama
- Auguste Kutschat
- Autumn Wood
- Aya Kawase
- Aya Tanaka
- Aya Yamanaka
- Ayako Imai
- Ayana Tatsuzawa
- Aydin Er
- Ayesha Ali
- Ayesha Irtiza-Ali
- Aziee Sudin
- Bader Al-Zeer
- Baigent Colin
- Bak Leong Goh
- Balwinder Gill
- Ban Chai Peng
- Baochun Guo
- Barbara Bartolomei Mecatti
- Barbara Tucky
- Barbara Winter-Goodwin
- Barbara Zander
- Barry Johns
- Beate Schumacher
- Bellovich Keith
- Ben Bagwell
- Ben Caplin
- Bernd Hohenstein
- Bernd Kruger
- Bernd Schroppel
- Bernd Stratmann
- Bernhard Banas
- Bernhard Kraemer
- Bernhard Winkelmann
- Bethelihem Gebeyehu
- Bhavya Kothapalli
- Bhrigu Sood
- Bhupinder Grewal
- Bianca Weber
- Bianka Rettenmaier
- Binbin Jin
- Bob Goodenough
- Bradley Eilerman
- Brandy Caudill
- Brenner Susanne
- Brian Camilleri
- Brigitte Fuchs
- Britta Brettschneider
- Britta Zemann
- Brittany Cleveland
- Brittany Golson
- Brittany Whitmore
- Brueckmann Martina
- Camille Galloway
- Cara Healy
- Carina Krieger
- Carl-Philipp Roesch
- Carlo Castillo
- Carlo Garofalo
- Carlos Hernandez-Cassis
- Carlos Martinez
- Carly McDonald
- Carol Buckman
- Carol Knott
- Caroline Blake
- Carolyn Hutchinson
- Cashmere Hardy
- Cassandra Johnson
- Cassandra Kimber
- Cat Guest
- Cath Byrne
- Cathy Jackson
- Cecilia Barnini
- Cesira Cafiero
- Chakradhar Velagapudi
- Charalampos Kriatselis
- Charles Daniels
- Charles Herzog
- Charlotte Kamundi
- Chee Koon Low
- Chek Loong Loh
- Chelsia Bao Tyng Chan
- Chen Cheng
- Chen Hua Ching
- Cheng Beng Goh
- Cherney David
- Chetna Tailor
- Cheung Alfred K
- Chiara Saccà
- Chiara Salviani
- Chidambaram Nethaji
- Chie Hashimoto
- Chie Saito
- Chigusa Higuchi
- Chigusa Yamashita
- Chiho Murakami
- Chika Kuribayashi
- Chimaki Unekawa
- Chintankumar Barot
- Chloe Bird
- Chong Men Leong
- Chris Bowler
- Chrissie Ambrose
- Christian Albert
- Christian Hartner
- Christian Hugo
- Christina Büttner
- Christina Reith
- Christine Bond
- Christine Braun
- Christine Brown
- Christine McClary-Wright
- Christine Meshykhi
- Christine Pötz
- Christoph Stellbrink
- Christoph Wanner
- Christopher Goldsmith
- Christopher Hill
- Christopher Marshall
- Christopher Provenzano
- Christopher Sze Bing Sim
- Christopher Wong
- Chuanwen Xu
- Chukwuma Chukwu
- Chun Leong Low
- Chye Chung Gan
- Cindy Castro
- Cindy Vanhoy
- Claire Burston
- Claire Sharpe
- Claire Shenton
- Clare Hui Hong Tan
- Clare Macdonald
- Claudia Donhauser
- Claudia Foellinger
- Claudia Hanf
- Claudia Schmidt
- Claudia Schneider-Danwitz
- Clorinda Falcone
- Cole Valletta
- Conception Pugay
- Concetta Gangemi
- Conor Moran
- Cristina Badin
- Cristina Calvi
- Curtis Knight
- Cynthia Mohandas
- Daisuke Sato
- Daisy Arteaga
- Damini Jeyarajah
- Daniel Kraus
- Daniel Pinto
- Daniel Steffl
- Daniela Farrugia
- Danijela Bovan
- Danny Sugimoto
- Daria Motta
- Darya Hosein
- David Bains
- David Cherney
- David Loader
- David MacLean
- David Preiss
- David Sutton
- David Tietjen
- Davina Hewitt
- Debasish Banerjee
- Debbie Domingo
- Debbie Griffin
- Deborah Glowski
- Deborah Lund
- Deirdre Fottrell-Gould
- Denise Donaldson
- Denise Fleming-Brown
- Denise Laurienti
- Dennis Karounos
- Deo Rajat
- Derrick Bennett
- Devasmita Dev
- Dheeptha Radhakrishnan
- Diane Campbell
- Diane Watkins
- Diethelm Tschope
- Diliana Draganova
- Divya Birudaraju
- Dolores Rijos
- Domenico Santoro
- Dominic Fellowes
- Dominik Alscher
- Dominik Stoffler
- Donald Fraser
- Donata Lucci
- Donatella Bilucaglia
- Doo Yee Mah
- Doreen Zhu
- Doris Poehler
- Dorleena Gowen
- Duncan Browne
- Eason Chang
- Edmond Limon
- Edward Kinsella-Perks
- Edward Pereira
- Edwin Wong
- Egbert Schulz
- Eiichiro Kanda
- Eilbracht Jens
- Eirini Lioudaki
- Eitaro Nakashima
- Ekaterina Stellbrink
- Elaine Fung
- Eleanor Damian
- Elena Brioni
- Elias Ugwu
- Elif Turan
- Elisa Joye Petr
- Elisabeth Bahlmann-Kroll
- Elisabeth Laundy
- Elissa Williams
- Elizabeta Matvienko
- Elizabeth Newman
- Elizabeth Swanson
- Elke Preiss
- Elke Schettler
- Elliyyin Katiman
- Emberson Jonathan R
- Emi Kuroda
- Emily Chang
- Emily Harding
- Emily Laity
- Emily Sammons
- Emily Tropman
- Emma McHaffie
- Emma Sadler
- Emmie Cole
- Enric Vilar
- Eri Kogure
- Eri Nagashima
- Eri Yanagisawa
- Eric Wines
- Erika Perez
- Eriko Takahira
- Erin Latore
- Ester Baldini
- Esther Zhao Zhi Tan
- Etsuo Yoshidome
- Eunice Doctolero
- Eva Voigt
- Eve Miller-Hodges
- Evelina Grobovaite
- Evelyn Nadar
- Ewelina Eckrich
- Exodus Edmerson
- Fadia Boreky
- Fairol Huda Ibrahim
- Fang Chen
- Fang Feng
- Farah Amalina Mohamed Affandi
- Farah Hanis Zulkipli
- Farah Latif
- Farid Ghalli
- Fariz Safhan Mohamad Nor
- Federica Tripodi
- Federico Alberici
- Fengmin Shao
- Filippo Aucella
- Filippo Fani
- Filippo Farnia
- Florian Sonntag
- Fortunata Zirino
- France Samson
- Frances Morris
- Francesca Bianchini
- Francesco Pesce
- Francesco Russo
- Francesco Scolari
- Francesco Totaro
- Francisco Aguilar
- Francois Dube
- Francois Madore
- Frank McCarroll
- Frank Strutz
- Franz Putz
- Franziska Klauser
- Franziska Scheidemantel
- Freda Driver
- Frederic Rahbari-Oskoui
- Fujiko Hasegawa
- Fulvia Zappulo
- Fuye Yang
- Gabriele Eden
- Gaetano La Manna
- Gagandeep Dhillon
- Gail Evans
- Gail Makos
- Genesis Naverrete
- Genielle Brewer
- Gennaro Santorelli
- Georg Rainer Schlieper
- George Thomas
- Georges Nakhoul
- Geraldine Hernandez
- Gerard Martins
- Gerhard Klausmann
- Gerhard Schmidt
- Gianna Fabbri
- Gianni Carraro
- Gillian Whalley
- Gina Morig
- Giorgio Gentile
- Giovanna Leoncini
- Giovanni Gambaro
- Giovanni Piccinni
- Girish Shivashankar
- Giulia Nobili
- Giuseppe Cianciolo
- Giuseppe Grandaliano
- Giuseppe Spatoliatore
- Giuseppe Vezzoli
- Giuseppina Pessolano
- Godson Oguchi
- Golriz Jafari
- Goto Shinya
- Green Jennifer B
- Gregory Greenwood
- Guanguo Cui
- Guillermo Jimenez
- Gunnar Heine
- Gunter Wolf
- Guylaine Marcotte
- Haitao Zhang
- Haiyan Lin
- Hajar Ahmad Rosdi
- Hajime Nagasu
- Hamish Woodhouse
- Hanako Hase
- Hanna Reiner
- Hannah Kingston
- Hannah Turner
- Hans Schmidt-Gurtler
- Hao Dai
- Harald Darius
- Hari Dukka
- Hari Nair
- Harish Pariani
- Harold Szerlip
- Harpreet Bajaj
- Haruhito Uchida
- Haruka Sasajima
- Hasnah Yahaya
- Hasnain Khandwala
- Hauske Sibylle J
- Haynes Richard
- Heather Edwards
- Heather Henderson
- Heba Nosseir
- Helen Clarke
- Helen Eldon
- Helen French
- Helen Lochhead
- Helen Sparks
- Henry Brown
- Hermann Haller
- Herrington William G
- Hesham Ammar
- Hideki Fujii
- Hideki Kamiya
- Hideki Katagiri
- Hideo Araki
- Hideyoshi Kaga
- Hikari Uchi
- Hilary Tindall
- Hill Michael
- Hima Yalamanchili
- Hin Seng Wong
- Hirayasu Kai
- Hiroaki Sato
- Hirokazu Sugiyama
- Hiroko Inazawa
- Hiromasa Goto
- Hiromi Komori
- Hiromi Shimoda
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- Yuka Sato
- Yuka Ueda
- Yukari Miura
- Yuki Fujita
- Yuki Fukao
- Yuki Omori
- Yukihiro Shimizu
- Yukihiro Yamaji
- Yukiko Nakayama
- Yukiko Toyonaga
- Yukiko Wakita
- Yuko Katsuda
- Yuko Makita
- Yuko Okada
- Yuko Orimo
- Yumi Osawa
- Yushi Hirota
- Yusuke Suzuki
- Yutaka Kamimura
- Yuya Nishida
- Yvette Webley
- Yvonne Ehrl
- Yvonne Jackson
- Zabrina Lozon
- Zaid Azhari
- Zaiha Harun
- Zainab Sheriff
- Zanaida Cooper
- Zay Htet
- Zhang Duan Tham
- Zhi-Hong Liu
- Zhirui Zhao
- Zhu Doreen
- Zhuo Tang
- Zohreh Forghani
- Zuber Patel
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2023
- Field of study
Background The effects of empagliflozin in patients with chronic kidney disease who are at risk for disease progression are not well understood. The EMPA-KIDNEY trial was designed to assess the effects of treatment with empagliflozin in a broad range of such patients. Methods We enrolled patients with chronic kidney disease who had an estimated glomerular filtration rate (eGFR) of at least 20 but less than 45 ml per minute per 1.73 m(2) of body-surface area, or who had an eGFR of at least 45 but less than 90 ml per minute per 1.73 m(2) with a urinary albumin-to-creatinine ratio (with albumin measured in milligrams and creatinine measured in grams) of at least 200. Patients were randomly assigned to receive empagliflozin (10 mg once daily) or matching placebo. The primary outcome was a composite of progression of kidney disease (defined as end-stage kidney disease, a sustained decrease in eGFR to < 10 ml per minute per 1.73 m(2), a sustained decrease in eGFR of & GE;40% from baseline, or death from renal causes) or death from cardiovascular causes. Results A total of 6609 patients underwent randomization. During a median of 2.0 years of follow-up, progression of kidney disease or death from cardiovascular causes occurred in 432 of 3304 patients (13.1%) in the empagliflozin group and in 558 of 3305 patients (16.9%) in the placebo group (hazard ratio, 0.72; 95% confidence interval [CI], 0.64 to 0.82; P < 0.001). Results were consistent among patients with or without diabetes and across subgroups defined according to eGFR ranges. The rate of hospitalization from any cause was lower in the empagliflozin group than in the placebo group (hazard ratio, 0.86; 95% CI, 0.78 to 0.95; P=0.003), but there were no significant between-group differences with respect to the composite outcome of hospitalization for heart failure or death from cardiovascular causes (which occurred in 4.0% in the empagliflozin group and 4.6% in the placebo group) or death from any cause (in 4.5% and 5.1%, respectively). The rates of serious adverse events were similar in the two groups. Conclusions Among a wide range of patients with chronic kidney disease who were at risk for disease progression, empagliflozin therapy led to a lower risk of progression of kidney disease or death from cardiovascular causes than placebo
DOCK2 is involved in the host genetics and biology of severe COVID-19
- Author
- Abe Ryuzo
- Abe Shinji
- Adachi Tomohiro
- Adachi Yuichi
- Ai Masumi
- Amishima Masaru
- Amiya Saori
- Anan Ryusuke
- Ando Akira
- Anzai Tatsuhiko
- Aoki Ryousuke
- Arai Daisuke
- Arai Ryosuke
- Arai Sawako
- Arakawa Kenichi
- Arimura Ken
- Asai Satoshi
- Asakura Takanori
- Asano Koichiro
- Awano Nobuyasu
- Azekawa Shuhei
- Azuma Masanori
- Baba Hiroaki
- Baba Rie
- Baba Tomoya
- Beppu Satoru
- Chiba Shigeru
- Chihara Yusuke
- Chubachi Shotaro
- Edahiro Ryuya
- Egi Moritoki
- Eguchi Hirotaka
- Endo Akifumi
- Endo Mayu
- Enomoto Takatoshi
- Eriguchi Yoshihiro
- Fuchimoto Yasuko
- Fujii Kazuhiko
- Fujimoto Nobukazu
- Fujita Kazue
- Fujitani Shigeki
- Fujiwara Akiko
- Fuke Satoshi
- Fukui Takahiro
- Fukui Yasutaka
- Fukui Yoshinori
- Fukunaga Koichi
- Fukushima Munehisa
- Fukusumi Takahito
- Fukuta Tetsuya
- Fukuyama Satoru
- Funatsu Yohei
- Furukawa Yoichi
- Gon Yasuhiro
- Hagihara Masao
- Hagimoto Satoshi
- Hagiwara Eri
- Hagiwara Shigehiro
- Hamamoto Junko
- Hanada Satoko
- Hara Reina
- Harada Masahiro
- Harada Norihiro
- Harada Sonoko
- Harada Yuko
- Haruta Yuki
- Hase Isano
- Hasegawa Naoki
- Hasegawa Takanori
- Hasegawa Yoshinori
- Hashiguchi Mizuha
- Hashimoto Naozumi
- Hashimoto Satoru
- Hashino Takuya
- Hattori Takeshi
- Hayashi Hiroyuki
- Hayashi Kentaro
- Hayashi Reina
- Hayashi Shinichi
- Hida Naoya
- Higashiyama Masahiko
- Hiki Makoto
- Hirai Yoshihiro
- Hiramatsu Yuji
- Hirano Toshiyuki
- Hiranuma Hisato
- Hirata Haruhiko
- Hirouchi Takatomo
- Hizawa Nobuyuki
- Honda Takayuki
- Horinouchi Hirohisa
- Hoshino Kota
- Hosoda Chiaki
- Hyugaji Takayoshi
- Ichikado Kazuya
- Ichimura Naoya
- Igarashi Akira
- Ihara Shoichi
- Ikemura Shinnosuke
- Imai Takao
- Imamura Tomonori
- Imoto Seiya
- Inohara Hidenori
- Inomata Minoru
- Inoue Sumito
- Inoue Takashi
- Inoue Takuya
- Inoue Yoshiaki
- Ishiguro Takashi
- Ishihara Rino
- Ishihara Sayoko
- Ishihara Shoichiro
- Ishii Makoto
- Ishii Tomoo
- Ishikawa Motonao
- Ishikura Hiroyasu
- Ishioka Kota
- Isogai Susumu
- Isono Taisuke
- Ito Akihiro
- Ito Fumimaro
- Ito Kazuto
- Ito Satoshi
- Ito Yoko
- Iwagoe Hajime
- Iwamura Hiromu
- Izumi Namiki
- Izumo Takehiro
- Kabata Hiroki
- Kagaya Takashi
- Kagyo Junko
- Kai Hirayasu
- Kamata Hirofumi
- Kamatani Yoichiro
- Kamimaki Isamu
- Kamiya Akane
- Kan-o Keiko
- Kanai Masahiro
- Kanai Masayuki
- Kanai Takanori
- Kanaoka Kensuke
- Kanayama Syuji
- Kanda Hidenori
- Kanehiro Arihiko
- Kaneko Yutaro
- Kaneyama Yasunari
- Kasamatsu Yu
- Kashiwada Takeru
- Katayama Kazuhiko
- Katayama Kotoe
- Kato Kazuto
- Kato Yasuhiro
- Kawabata Shuhei
- Kawada Miki
- Kawamura Kodai
- Kawamura Yusuke
- Kawana Akihiko
- Kawana Masatoshi
- Kawashima Hidetoshi
- Kijima Noriyuki
- Kikuchi Ryota
- Kimizuka Yoshifumi
- Kimura Akinori
- Kimura Nozomu
- Kimura Tomoki
- Kimura Tomoyuki
- Kimura Yasuhiro
- Kishi Hiroto
- Kishikawa Toshihiro
- Kishima Haruhiko
- Kita Toshiyuki
- Kitagawa Yuichiro
- Kitagawa Yuko
- Kitamura Hideya
- Kobayashi Keigo
- Kobayashi Yoichi
- Kodaka Norio
- Kodama Nobuhiro
- Koh Hidefumi
- Kohashi Sumiko
- Koike Ryuji
- Koji Sakamoto
- Kojima Mitsuaki
- Kokuto Hiroyuki
- Komase Yuko
- Komuta Kiyoshi
- Konishi Shunichiro
- Kono Yuta
- Koretsune Yukihiro
- Koshida Kiyoshi
- Kozu Yutaka
- Kuge Tomoki
- Kumanogoh Atsushi
- Kuraki Takashige
- Kuramochi Mizuki
- Kurihara Yuko
- Kusaka Yu
- Kuse Naoyuki
- Kuwahara Naota
- Lee Ho
- Liu Yu-Chen
- Maeda Shunsuke
- Maeda Yuichi
- Maeno Toshitaka
- Makino Shohei
- Makino Yasushi
- Manabe Tadashi
- Maruyama Junichi
- Maruyama Shuhei
- Masaki Katsunori
- Mashimo Shuko
- Masuda Makoto
- Masumoto Akihide
- Masuzawa Keita
- Matsubara Yuta
- Matsuda Fumihiko
- Matsuda Koichi
- Matsui Yuma
- Matsumoto Kinnosuke
- Matsumoto Koichiro
- Matsumoto Shuichiro
- Matsumoto Takemasa
- Matsunaga Tomohiro
- Matsuo Hirotaka
- Matsuse Hiroto
- Matsushita Yasushi
- Mikami Yohei
- Minami Shiro
- Minemura Hiroyuki
- Mitamura Keiko
- Miyagawa Kazuya
- Miyake Takahito
- Miyano Satoru
- Miyawaki Masayoshi
- Miyawaki Satoru
- Miyazaki Masatoshi
- Miyazaki Yasunari
- Miyazaki Yoshimune
- Miyazawa Naoki
- Mochimaru Takao
- Mori Nobuaki
- Morikawa Daiki
- Morisaki Hiroshi
- Morisaki Takayuki
- Morita Atsuho
- Morita Takayoshi
- Motegi Mitsuru
- Motooka Daisuke
- Murakami Koji
- Murakami Teruaki
- Murakami Yoshinori
- Muranaka Hiroyuki
- Murayama Shigeo
- Murohashi Kota
- Muto Kaori
- Mutoh Yoshikazu
- Nagai Akiko
- Nagai Hideaki
- Nagao Genta
- Nagasaka Tomoki
- Nagasaki Tadao
- Nagasaki Yoji
- Nagata Kaoru
- Nagayama Satoshi
- Naito Tatsuhiko
- Naito Toshio
- Naito Yoko
- Nakachi Ichiro
- Nakada Taka-Aki
- Nakajima Jun
- Nakajima Yukiko
- Nakamori Yasushi
- Nakamura Ai
- Nakamura Kazunori
- Nakamura Morio
- Nakamura Yoshihiko
- Nakano Chihiro
- Nakano Yasushi
- Nakatsumi Hiroki
- Nakayama Akiyoshi
- Nakayama Sohei
- Namba Shinichi
- Namkoong Ho
- Nanki Kosaku
- Nannya Yasuhito
- Narita Atsuya
- Narumoto Osamu
- Nii Takuro
- Niitsu Takayuki
- Nikaido Takefumi
- Nishi Koichi
- Nishida Takashi
- Nishihara Hiroshi
- Nishikawa Masanori
- Nishimura Tomoyasu
- Nishio Kazumi
- Nishitsuji Masaru
- Nishiyama Kei
- Nishiyama Kenta
- Niwa Kazuki
- Noda Yoshimi
- Noguchi Yoichiro
- Nukaga Shigenari
- Obara Wataru
- Obata Daisuke
- Ochi Junichi
- Odani Toshio
- Odate Mitsuru
- Ogata Hideo
- Ogata Tomouki
- Ogawa Aki
- Ogawa Seishi
- Ogawa Shinichi
- Oguma Tsuyoshi
- Ogura Shinji
- Ogura Takashi
- Ogura Takayuki
- Ohba Takehiko
- Ohira Yoshiyuki
- Ohta Kazuhide
- Ohta Ken
- Ohta Shin
- Okabayashi Hiroko
- Okada Takenori
- Okada Yukinori
- Okamori Satoshi
- Okamoto Masaki
- Okudela Koji
- Okuzaki Daisuke
- Omae Yosuke
- Omote Norihito
- Ono Akihiro
- Ono Hiroshi
- Ono Yoshinao
- Onoi Keisuke
- Ooshima Nobuharu
- Osawa Takeshi
- Oshima Taku
- Oshio Takeshi
- Ota Sho
- Oyama Baku
- Oyamada Yoshitaka
- Ozaki Shinji
- Sado Reiko
- Sado Toshikatsu
- Sagara Hironori
- Sageshima Hisako
- Saiki Ryunosuke
- Saito Fukuki
- Saito Fumitake
- Saito Hiroshi
- Saito Ryuichi
- Saito Yoshinobu
- Sakagami Satoru
- Sakakibara Shuhei
- Sakurai Toshihiro
- Sano Hirohito
- Sano Tomoya
- Sasa Noah
- Sasaki Junichi
- Sasaki Kana
- Sasano Hajime
- Sasano Hitoshi
- Sassa Chihiro Tani
- Sato Masamichi
- Sato Ryuichi
- Sato Tomonori
- Sato Toshiro
- Sato Yoko
- Sato Yuki
- Satomi Ryosuke
- Seike Masahiro
- Sekikawa Yoshiyuki
- Shibata Shun
- Shibata Yoko
- Shibusawa Takayuki
- Shichinohe Yasuo
- Shimada Hisato
- Shimada Tadanaga
- Shimizu Eigo
- Shimizu Tetsuo
- Shimo Masatoshi
- Shimoda Masafumi
- Shinoki Masato
- Shinozuka Jun
- Shinozuka Keisuke
- Shiomi Tetsuya
- Shirai Yuya
- Shiroyama Takayuki
- Shoko Tomohisa
- Sinozaki Nobuaki
- Sonehara Kyuto
- Sonobe Kazunari
- Suematsu Ryohei
- Sueyoshi Atsushi
- Sugihara Fuminori
- Sugimoto Hideyasu
- Sugiura Hisatoshi
- Suzuki Junya
- Suzuki Ken
- Suzuki Motoyuki
- Suzuki Shoji
- Suzuki Takao
- Suzuki Yusuke
- Tachikawa Natsuo
- Tada Ai
- Tagaya Etsuko
- Takada Minoru
- Takagaki Masatoshi
- Takagi Haruhi
- Takahashi Hidenori
- Takahashi Hiroshi
- Takahashi Kazuhisa
- Takahashi Kenichiro
- Takahashi Kunihiko
- Takahashi Mai
- Takahashi Meiko
- Takahashi Saeko
- Takahashi Takeshi
- Takahashi Yasuo
- Takaku Yotaro
- Takano Kenji
- Takano Tomomi
- Takaoka Hatsuyo
- Takata Tohru
- Takayanagi Noboru
- Takeda Yoshito
- Takei Reoto
- Takemoto Norihiko
- Takeuchi Mayumi
- Taki Reiko
- Takita Mumon
- Takoi Hiroyuki
- Takuwa Ayako
- Tanaka Akihiko
- Tanaka Hiromu
- Tanaka Toru
- Tanaka Yoshiaki
- Tani Mayuko
- Tanino Yoshinori
- Tateishi Tomoya
- Tateno Hiroki
- Terai Hideki
- Terashima Mariko
- Togashi Yuki
- Tohda Shuji
- Tokunaga Katsushi
- Tokunaga Yoshihisa
- Tominaga Yoshiteru
- Tomono Kazunori
- Tone Mari
- Tsuburai Takahiro
- Tsuchida Tomoya
- Uchida Sho
- Uchida Tomoyuki
- Uchimura Yuji
- Ueda Ken
- Ueda Soichiro
- Ueda Suguru
- Ueda Tetsuya
- Ueno Takafumi
- Ueno Yuya
- Umeda Akira
- Uno Shunsuke
- Utsugi Mitsuyoshi
- Uwamino Yoshifumi
- Wada Daiki
- Wada Sae
- Wakabayashi Aya
- Wakahara Keiko
- Wang Qingbo S.
- Watanabe Chie
- Watanabe Hiroki
- Watanabe Hiroko
- Watanabe Kazuyoshi
- Watanabe Masafumi
- Wing James B.
- Yagi Kazuma
- Yamada Mitsuhiro
- Yamada Shuhei
- Yamada Yuichiro
- Yamagata Kunihiro
- Yamaguchi Hiroki
- Yamaguchi Yuta
- Yamaji Ken
- Yamamoto Kenichi
- Yamamoto Makoto
- Yamamoto Masaomi
- Yamamoto Yuji
- Yamanashi Yuji
- Yamano Yasuhiko
- Yamasaki Masaki
- Yamashita Tatsuya
- Yanagita Emmy
- Yasui Yoshinori
- Yatomi Masakiyo
- Yokote Koutaro
- Yoneda Midori
- Yonekawa Akiko
- Yoshida Eriko
- Yoshida Kosuke
- Yoshida Shozo
- Yoshida Shuichi
- Yoshida Toru
- Yoshifuji Ayumi
- Yoshihara Tomoyuki
- Yoshimori Kozo
- Yoshimura Yukihiro
- Yoshiya Kazuhisa
- Yoshiyama Takashi
- 井元 清哉
- 佐伯 龍之介
- 佐藤 俊朗
- 北川 雄光
- 南宮 湖
- 南谷 泰仁
- 宮野 悟
- 小川 誠司
- 小池 竜司
- 岡田 随象
- 木村 彰方
- 松田 文彦
- 枝廣 龍哉
- 熊ノ郷 淳
- 片山 和彦
- 石井 誠
- 福永 興壱
- 藍 真澄
- 西原 広史
- 金井 隆典
- 長谷川 直樹
- 高橋 めい子
- 高野 友美
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study