An improved \eps expansion for three-dimensional turbulence: two-loop renormalization near two dimensions

An improved \eps expansion in the $d$-dimensional ($d > 2$) stochastic theory of turbulence is constructed at two-loop order which incorporates the effect of pole singularities at $d \to 2$ in coefficients of the \eps expansion of universal quantities. For a proper account of the effect of these singularities two different approaches to the renormalization of the powerlike correlation function of the random force are analyzed near two dimensions. By direct calculation it is shown that the approach based on the mere renormalization of the nonlocal correlation function leads to contradictions at two-loop order. On the other hand, a two-loop calculation in the renormalization scheme with the addition to the force correlation function of a local term to be renormalized instead of the nonlocal one yields consistent results in accordance with the UV renormalization theory. The latter renormalization prescription is used for the two-loop renormalization-group analysis amended with partial resummation of the pole singularities near two dimensions leading to a significant improvement of the agreement with experimental results for the Kolmogorov constant.Comment: 23 pages, 2 figure

Stability of scaling regimes in d≥2d\geq 2 developed turbulence with weak anisotropy

The fully developed turbulence with weak anisotropy is investigated by means of renormalization group approach (RG) and double expansion regularization for dimensions $d\ge 2$. Some modification of the standard minimal substraction scheme has been used to analyze stability of the Kolmogorov scaling regime which is governed by the renormalization group fixed point. This fixed point is unstable at $d=2$; thus, the infinitesimally weak anisotropy destroyes above scaling regime in two-dimensional space. The restoration of the stability of this fixed point, under transition from $d=2$ to $d=3,$ has been demonstrated at borderline dimension $2<d_c<3$. The results are in qualitative agreement with ones obtained recently in the framework of the usual analytical regularization scheme.Comment: 23 pages, 2 figure

SynGAP isoforms exert opposing effects on synaptic strength

Peer reviewedPublisher PD

Influence of compressibility on scaling regimes of strongly anisotropic fully developed turbulence

Statistical model of strongly anisotropic fully developed turbulence of the weakly compressible fluid is considered by means of the field theoretic renormalization group. The corrections due to compressibility to the infrared form of the kinetic energy spectrum have been calculated in the leading order in Mach number expansion. Furthermore, in this approximation the validity of the Kolmogorov hypothesis on the independence of dissipation length of velocity correlation functions in the inertial range has been proved.Comment: REVTEX file with EPS figure

Vacuum Ambiguity in de Sitter Space at Strong Coupling

It is well known that in the weak coupling regime, quantum field theories in de Sitter space do not have a unique vacuum, but a class of vacua parametrized by a complex parameter $\alpha$, i.e., the so-called $\alpha$-vacua. In this article, using gauge/gravity duality, we calculate the symmetric two-point function of strongly coupled ${\cal N}=4$ supersymmetric Yang-Mills theory on $dS_3$. We find that there is a class of de Sitter invariant vacua, parametrized by a set of complex parameters $\{\alpha_{\nu}\}$.Comment: 17 pages in JHEP style, references adde

Anomalous scaling of a passive scalar advected by the turbulent velocity field with finite correlation time and uniaxial small-scale anisotropy

The influence of uniaxial small-scale anisotropy on the stability of the scaling regimes and on the anomalous scaling of the structure functions of a passive scalar advected by a Gaussian solenoidal velocity field with finite correlation time is investigated by the field theoretic renormalization group and operator product expansion within one-loop approximation. Possible scaling regimes are found and classified in the plane of exponents $\epsilon-\eta$, where $\epsilon$ characterizes the energy spectrum of the velocity field in the inertial range $E\propto k^{1-2\epsilon}$, and $\eta$ is related to the correlation time of the velocity field at the wave number $k$ which is scaled as $k^{-2+\eta}$. It is shown that the presence of anisotropy does not disturb the stability of the infrared fixed points of the renormalization group equations which are directly related to the corresponding scaling regimes. The influence of anisotropy on the anomalous scaling of the structure functions of the passive scalar field is studied as a function of the fixed point value of the parameter $u$ which represents the ratio of turnover time of scalar field and velocity correlation time. It is shown that the corresponding one-loop anomalous dimensions, which are the same (universal) for all particular models with concrete value of $u$ in the isotropic case, are different (nonuniversal) in the case with the presence of small-scale anisotropy and they are continuous functions of the anisotropy parameters, as well as the parameter $u$. The dependence of the anomalous dimensions on the anisotropy parameters of two special limits of the general model, namely, the rapid-change model and the frozen velocity field model, are found when $u\to \infty$ and $u\to 0$, respectively.Comment: revtex, 25 pages, 37 figure

Anomalous scaling, nonlocality and anisotropy in a model of the passively advected vector field

A model of the passive vector quantity advected by a Gaussian time-decorrelated self-similar velocity field is studied; the effects of pressure and large-scale anisotropy are discussed. The inertial-range behavior of the pair correlation function is described by an infinite family of scaling exponents, which satisfy exact transcendental equations derived explicitly in d dimensions. The exponents are organized in a hierarchical order according to their degree of anisotropy, with the spectrum unbounded from above and the leading exponent coming from the isotropic sector. For the higher-order structure functions, the anomalous scaling behavior is a consequence of the existence in the corresponding operator product expansions of ``dangerous'' composite operators, whose negative critical dimensions determine the exponents. A close formal resemblance of the model with the stirred NS equation reveals itself in the mixing of operators. Using the RG, the anomalous exponents are calculated in the one-loop approximation for the even structure functions up to the twelfth order.Comment: 37 pages, 4 figures, REVTe

Systems thinking creates opportunities for a circular economy and sustainable palm agriculture in Africa

Palm agriculture has received strong criticism in recent years due to its link with deforestation, especially in Asia. Here we propose that there is instead an opportunity for sustainable palm futures in Africa. Applying interdisciplinary systems thinking and circular production models, food and economic security can be achieved sustainably by (i) promoting integrated production of nutritionally valuable insect and fungal protein using palm crop waste; (ii) increasing resilience and productivity of crop palms in the harsh tropical climates of sub-Saharan Africa; and (iii) promoting the development of palm plantations as biodiverse agroforestry ecosystems

Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-seq and ESTs

The reference annotations made for a genome sequence provide the framework for all subsequent analyses of the genome. Correct annotation is particularly important when interpreting the results of RNA-seq experiments where short sequence reads are mapped against the genome and assigned to genes according to the annotation. Inconsistencies in annotations between the reference and the experimental system can lead to incorrect interpretation of the effect on RNA expression of an experimental treatment or mutation in the system under study. Until recently, the genome-wide annotation of 3-prime untranslated regions received less attention than coding regions and the delineation of intron/exon boundaries. In this paper, data produced for samples in Human, Chicken and A. thaliana by the novel single-molecule, strand-specific, Direct RNA Sequencing technology from Helicos Biosciences which locates 3-prime polyadenylation sites to within +/- 2 nt, were combined with archival EST and RNA-Seq data. Nine examples are illustrated where this combination of data allowed: (1) gene and 3-prime UTR re-annotation (including extension of one 3-prime UTR by 5.9 kb); (2) disentangling of gene expression in complex regions; (3) clearer interpretation of small RNA expression and (4) identification of novel genes. While the specific examples displayed here may become obsolete as genome sequences and their annotations are refined, the principles laid out in this paper will be of general use both to those annotating genomes and those seeking to interpret existing publically available annotations in the context of their own experimental dataComment: 44 pages, 9 figure

Design principles for riboswitch function

Scientific and technological advances that enable the tuning of integrated regulatory components to match network and system requirements are critical to reliably control the function of biological systems. RNA provides a promising building block for the construction of tunable regulatory components based on its rich regulatory capacity and our current understanding of the sequence–function relationship. One prominent example of RNA-based regulatory components is riboswitches, genetic elements that mediate ligand control of gene expression through diverse regulatory mechanisms. While characterization of natural and synthetic riboswitches has revealed that riboswitch function can be modulated through sequence alteration, no quantitative frameworks exist to investigate or guide riboswitch tuning. Here, we combined mathematical modeling and experimental approaches to investigate the relationship between riboswitch function and performance. Model results demonstrated that the competition between reversible and irreversible rate constants dictates performance for different regulatory mechanisms. We also found that practical system restrictions, such as an upper limit on ligand concentration, can significantly alter the requirements for riboswitch performance, necessitating alternative tuning strategies. Previous experimental data for natural and synthetic riboswitches as well as experiments conducted in this work support model predictions. From our results, we developed a set of general design principles for synthetic riboswitches. Our results also provide a foundation from which to investigate how natural riboswitches are tuned to meet systems-level regulatory demands