Ovarian cancer molecular pathology.

Peer reviewe

ICAR: endoscopic skull‐base surgery

n/

A household-based survey of knowledge, attitudes and practices towards dengue fever among local urban communities in Taiz Governorate, Yemen

BACKGROUND: Yemen has witnessed several dengue fever outbreaks coincident with the social unrest and war in the country. The aim of the present study was to describe the knowledge, attitudes and practices (KAPs) of at-risk urban populations residing in Taiz, southwest of Yemen. In addition, factors possibly associated with poor preventive practices were investigated. METHODS: A household-based, cross-sectional survey was conducted in three urban districts encompassing 383 households. Data on the socio-demographic characteristics and KAPs of the participating household heads were collected using a pre-designed, structured questionnaire. The association of socio-demographic characteristics, knowledge and attitudes of the population with poor preventive practices against dengue fever was then analyzed using logistic regression. RESULTS: More than 90.0 % of respondent household heads had correct knowledge about fever, headache and joint pain as common signs and symptoms of dengue fever. Moreover, muscular pain and bleeding were perceived by more than 80.0 % of the respondents as being associated with dengue fever; however, only 65.0 % of the respondents reported skin rash as a sign of dengue fever. More than 95.0 % of respondents agreed about the seriousness and possible transmission of dengue fever; however, negative attitudes regarding the facts of being at risk of the disease and that the infection is preventable were expressed by 15.0 % of respondents. Despite the good level of knowledge and attitudes of the respondent population, poor preventive practices were common. Bivariate analysis identified poor knowledge of dengue signs and symptoms (OR = 2.1, 95 % CI = 1.24–3.68; P = 0.005) and its vector (OR = 2.1, 95 % CI = 1.14–3.84; P = 0.016) as factors significantly associated with poor preventive practices. However, multivariable analysis showed that poor knowledge of the vector is an independent predictor of poor preventive practices of the population (adjusted OR = 2.1, 95 % CI = 1.14–3.84; P = 0.018). CONCLUSION: The majority of people in urban communities of Taiz have a clear understanding of most signs/symptoms of dengue fever as well as positive attitudes towards the seriousness and possible transmissibility of dengue fever. However, negative attitudes regarding their perception of the risk and possible prevention of the infection are prevailing among a small proportion of the population and need to be targeted by educational campaigns. It appears that the good level of the population knowledge of the signs/symptoms of dengue fever and the factors contributing to the spread and control of its vectors did not translate into good practices

Revisiting probabilistic seismic hazard analysis of Gujarat: an assessment of Indian design spectra

Seismic hazard assessment is the key tool for rational planning, safety and design of infrastructures in seismically vulnerable regions. Gujarat is the only state in peninsular India with the maximum seismic hazard of large shallow earthquakes originating from intra-plate seismicity. Probabilistic seismic hazard assessment (PSHA) of Gujarat is carried out in this paper. Three seismogenic sources, namely Kutch, Saurashtra and Mainland Gujarat, are considered, and seismicity parameters are estimated separately for each region taking into account the completeness of the available earthquake data. Peak ground acceleration (PGA) of the horizontal component and spectral acceleration at specific periods are considered as the intensity measures. Ground motion predictive equation chosen was reported to be based on simulated ground motions and verified against the strong motion records in the study region. Results are reported for the 17 major cities at the bedrock and also for the soil sites. Apart from hazard curves, 2475 and 475 years of return periods are considered for the PGA and uniform hazard spectra (UHS). The results are compared with the present recommendations of Indian Standards. Key observations include (1) Indian Standards underpredict PGA in the entire Gujarat when the soil sites are considered and in a few cities even at the bedrock; (2) amplification of PGA (or short period hazard) on account of soil sites should be included in the Indian Standard, which is currently absent; (3) shape of the UHS indicates that a separate amplification is required at the hyperbolic portion; and (4) ratio of 2475–475 years of PGA, which is considered 2.0 in Indian Standard, should be reduced to 1.5. Time-dependent recurrence model is also included in this paper and compared with conventional PSHA. General observations include that (1) hazard may increase significantly on account of time dependency; (2) this also influences the disaggregation and in turn the selection of ground motions; and (3) time since last earthquake significantly influences the extent of the effect of time dependency.by Asim Bashir and Dhiman Bas