Vais-je publier ce résumé? Déterminer les caractéristiques de résumés de présentations orales associés au potentiel de publication

Background: Prior studies have shown that most conference submissions fail to be published. Understanding factors that facilitate publication may be of benefit to authors. Using data from the Canadian Conference on Medical Education (CCME), our goal was to identify characteristics of conference submissions that predict the likelihood of publication with a specific focus on the utility of peer-review ratings. Methods: Study characteristics (scholarship type, methodology, population, sites, institutions) from all oral abstracts from 2011-2015 and peer-review ratings for 2014-2015 were extracted by two raters. Publication data was obtained using online database searches. The impact of variables on publication success was analyzed using logistic regressions. Results: Of 531 abstracts with peer-review ratings, 162 (31%) were published. Of the 9 analyzed variables, those associated with a greater odds of publication were: multiple vs. single institutions (odds ratio (OR) = 1.72), post-graduate research vs. others (OR=1.81) and peer-review ratings (OR=1.60). Factors with decreased odds of publication were curriculum development (OR=0.17) and innovation vs. others (OR=0.22).     Conclusion: Similar to other studies, the publication rate of CCME presentations is low. However, peer ratings were predictive of publication success suggesting that ratings could be a useful form of feedback to authors.  Contexte : Des études ont montré que la plupart des résumés soumis pour présentations orales ne sont pas ultérieurement publiés. Il pourrait être utile aux auteurs de comprendre les facteurs qui favorisent la publication. À l’aide de données provenant de la Conférence canadienne sur l’éducation médicale (CCÉM), notre objectif était d’identifier les caractéristiques des résumés permettant de prédire les chances de publication et en particulier l’utilité des cotes attribuées par les réviseurs. Méthodologie : Les caractéristiques des études (type de projet d’érudition, méthodologie, population, établissements, institutions) de tous les résumés de présentation orale soumis pour les conférences de 2011 à 2015 et les cotes attribuées par les réviseurs entre 2014 et 2015 ont été extraites par deux évaluateurs. On a obtenu des données de publication en faisant des recherches dans des bases de données en ligne.  L’effet des variables sur le potentiel de publication a été examiné à l’aide de régressions logistiques. Résultats : Au total, 953 résumés ont été révisé des années 2011 à 2015. Le taux de publication était de 30.5% (291/953) en somme. Des 531 résumés ayant été évalués des pairs, entre 2014 et 2015, 162 (31 %) ont été publiés. Parmi les neuf variables analysées, celles qui ont été associées à un nombre élevé de chances de publication étaient les suivantes : projet multi-institutionnel par rapport à institution unique (risque relatif (RR) = 1,72), travaux de recherche post-graduée par rapport à d’autres types (RR = 1,81) et présence de cotes attribuées par les réviseurs (RR = 1,6). Les facteurs associés à des moindres chances de publication étaient les suivants : articles portant sur le développement de cursus (RR = 0,17) et les innovations, par rapport à d’autres (RR = 0,22).     Conclusion :  Comme ce fut le cas pour d’autres études, le taux de publication à la suite d’une présentation au CCME est faible.  Cependant, les cotes attribuées par les réviseurs permettaient de prédire les chances de publication ce qui semble indiquer que les cotes pourraient constituer une forme de rétroaction utile aux auteurs

Qualité des données hydrométriques prédites par une approche machine learning dans l’évaluation de la ressource en eau au nord de la Cote d’Ivoire

L'écoulement des rivières revêt un intérêt particulier dans la gestion rationnelle des ressources en eau. Son estimation permet d'évaluer quantitativement la disponibilité des ressources en eau, ainsi que de prévenir des catastrophes naturelles telles que les inondations et les sécheresses. Ces estimations, généralement effectuées à l'aide de méthodes statistiques ou d'apprentissage automatique, sont parfois biaisées, entraînant des écarts par rapport aux observations in situ. Cette étude a pour objectif d'analyser la qualité des données de débit de la rivière Bagoé prédites par des réseaux neuronaux, afin d'aider les décideurs dans leurs projets de développement durable. Pour ce faire, deux modèles basés sur des réseaux neuronaux ont été développés pour prévoir les variations des débits mensuels de la rivière Bagoé aux instants t et t+3 respectivement. Les modèles sont validés en utilisant le critère de Nash (%), le coefficient de corrélation de Pearson (R), le rapport du débit maximal et le critère de robustesse. Les résultats obtenus indiquent que les modèles neuronaux développés expliquent plus de 82 % des débits mensuels de la rivière Bagoé. Ceux-ci variaient respectivement de 0,002 m3s-1 à 300,12 m3s-1, avec une moyenne de 31,10 m3s-1 en calibration, et de 0,002 m3s-1 à 243,32 m3s-1, avec une moyenne de 31,29 m3s-1 en validation. Cependant, certains décalages dans les débits extrêmes ont été observés à la fois en calibration et en validation.   River flow is of particular interest in the rational management of water resources. Their estimation enables quantitative assessment of water resource availability, as well as anticipation of natural disasters such as floods and droughts. These estimates, generally made using statistical methods or machine learning, are sometimes biased, resulting in variations that differ from those observed in situ. The aim of this study is to analyze the quality of flow data for the Bagoé River predicted by neural networks, in order to help decision-makers in their sustainable development projects. To achieve this, two neural network-based models were developed to forecast variations in monthly flows in the Bagoé River at time t and time t+3 respectively. The models are validated using the Nash criterion (%), Pearson's correlation coefficient (R), the maximum flow ratio and the robustness criterion. The results obtained indicate that the neural models developed expressed more than 82% of the monthly flows of the Bagoé River. These ranged respectively from 0.002 m3s-1 to 300.12 m3s-1, with an average of 31.10 m3s-1 in calibration, and 0.002 m3s-1 to 243.32 m3s-1, with an average of 31.29 m3s-1 in validation. However, some shifts in extreme flows were observed in both calibration and validation

Genome-wide association study of a panel of vietnamese rice landraces reveals new QTLs for tolerance to water deficit during the vegetative phase

Background: Drought tolerance is a major challenge in breeding rice for unfavorable environments. In this study, we used a panel of 180 Vietnamese rice landraces genotyped with 21,623 single-nucleotide polymorphism markers to perform a genome-wide association study (GWAS) for different drought response and recovery traits during the vegetative stage. These landraces originate from different geographical locations and are adapted to different agrosystems characterized by contrasted water regimes. Vietnamese landraces are often underrepresented in international panels used for GWAS, but they can contain original genetic determinants related to drought resistance. Results: The panel of 180 rice varieties was phenotyped under greenhouse conditions for several drought-related traits in an experimental design with 3 replicates. Plants were grown in pots for 4 weeks and drought-stressed by stopping irrigation for an additional 4 weeks. Drought sensitivity scores and leaf relative water content were measured throughout the drought stress. The recovery capacity was measured 2 weeks after plant rewatering. Several QTLs associated with these drought tolerance traits were identified by GWAS using a mixed model with control of structure and kinship. The number of detected QTLs consisted of 14 for leaf relative water content, 9 for slope of relative water content, 12 for drought sensitivity score, 3 for recovery ability and 1 for relative crop growth rate. This set of 39 QTLs actually corresponded to a total of 17 different QTLs because 9 were simultaneously associated with two or more traits, which indicates that these common loci may have pleiotropic effects on drought-related traits. No QTL was found in association with the same traits in both the indica and japonica subpanels. The possible candidate genes underlying the quantitative trait loci are reviewed. Conclusions: Some of the identified QTLs contain promising candidate genes with a function related to drought tolerance by osmotic stress adjustment

Forecasting malaria incidence based on monthly case reports and environmental factors in Karuzi, Burundi, 1997–2003

BACKGROUND: The objective of this work was to develop a model to predict malaria incidence in an area of unstable transmission by studying the association between environmental variables and disease dynamics. METHODS: The study was carried out in Karuzi, a province in the Burundi highlands, using time series of monthly notifications of malaria cases from local health facilities, data from rain and temperature records, and the normalized difference vegetation index (NDVI). Using autoregressive integrated moving average (ARIMA) methodology, a model showing the relation between monthly notifications of malaria cases and the environmental variables was developed. RESULTS: The best forecasting model (R2adj = 82%, p < 0.0001 and 93% forecasting accuracy in the range +/- 4 cases per 100 inhabitants) included the NDVI, mean maximum temperature, rainfall and number of malaria cases in the preceding month. CONCLUSION: This model is a simple and useful tool for producing reasonably reliable forecasts of the malaria incidence rate in the study area

A giant comet-like cloud of hydrogen escaping the warm Neptune-mass exoplanet GJ 436b

Exoplanets orbiting close to their parent stars could lose some fraction of their atmospheres because of the extreme irradiation. Atmospheric mass loss primarily affects low-mass exoplanets, leading to suggest that hot rocky planets might have begun as Neptune-like, but subsequently lost all of their atmospheres; however, no confident measurements have hitherto been available. The signature of this loss could be observed in the ultraviolet spectrum, when the planet and its escaping atmosphere transit the star, giving rise to deeper and longer transit signatures than in the optical spectrum. Here we report that in the ultraviolet the Neptune-mass exoplanet GJ 436b (also known as Gliese 436b) has transit depths of 56.3 +/- 3.5% (1 sigma), far beyond the 0.69% optical transit depth. The ultraviolet transits repeatedly start ~2 h before, and end >3 h after the ~1 h optical transit, which is substantially different from one previous claim (based on an inaccurate ephemeris). We infer from this that the planet is surrounded and trailed by a large exospheric cloud composed mainly of hydrogen atoms. We estimate a mass-loss rate in the range of ~10^8-10^9 g/s, which today is far too small to deplete the atmosphere of a Neptune-like planet in the lifetime of the parent star, but would have been much greater in the past.Comment: Published in Nature on 25 June 2015. Preprint is 28 pages, 12 figures, 2 table

Systematic literature review of determinants of sedentary behaviour in older adults:a DEDIPAC study

BACKGROUND: Older adults are the most sedentary segment of society and high sedentary time is associated with poor health and wellbeing outcomes in this population. Identifying determinants of sedentary behaviour is a necessary step to develop interventions to reduce sedentary time. METHODS: A systematic literature review was conducted to identify factors associated with sedentary behaviour in older adults. Pubmed, Embase, CINAHL, PsycINFO and Web of Science were searched for articles published between 2000 and May 2014. The search strategy was based on four key elements: (a) sedentary behaviour and its synonyms; (b) determinants and its synonyms (e.g. correlates, factors); (c) types of sedentary behaviour (e.g. TV viewing, sitting, gaming) and (d) types of determinants (e.g. environmental, behavioural). Articles were included in the review if specific information about sedentary behaviour in older adults was reported. Studies on samples identified by disease were excluded. Study quality was rated by means of QUALSYST. The full review protocol is available from PROSPERO (PROSPERO 2014: CRD42014009823). The analysis was guided by the socio-ecological model framework. RESULTS: Twenty-two original studies were identified out of 4472 returned by the systematic search. These included 19 cross-sectional, 2 longitudinal and 1 qualitative studies, all published after 2011. Half of the studies were European. The study quality was generally high with a median of 82 % (IQR 69-96 %) using Qualsyst tool. Personal factors were the most frequently investigated with consistent positive association for age, negative for retirement, obesity and health status. Only four studies considered environmental determinants suggesting possible association with mode of transport, type of housing, cultural opportunities and neighbourhood safety and availability of places to rest. Only two studies investigated mediating factors. Very limited information was available on contexts and sub-domains of sedentary behaviours. CONCLUSION: Few studies have investigated determinants of sedentary behaviour in older adults and these have to date mostly focussed on personal factors, and qualitative studies were mostly lacking. More longitudinal studies are needed as well as inclusion of a broader range of personal and contextual potential determinants towards a systems-based approach, and future studies should be more informed by qualitative work

Complete mitochondrial DNA sequences provide new insights into the Polynesian motif and the peopling of Madagascar

More than a decade of mitochondrial DNA (mtDNA) studies have given the 'Polynesian motif' renowned status as a marker for tracing the late-Holocene expansion of Austronesian speaking populations. Despite considerable research on the Polynesian motif in Oceania, there has been little equivalent work on the western edge of its expansion - leaving major issues unresolved regarding the motif's evolutionary history. This has also led to considerable uncertainty regarding the settlement of Madagascar. In this study, we assess mtDNA variation in 266 individuals from three Malagasy ethnic groups: the Mikea, Vezo, and Merina. Complete mtDNA genome sequencing reveals a new variant of the Polynesian motif in Madagascar; two coding region mutations define a Malagasy-specific sub-branch. This newly defined 'Malagasy motif' occurs at high frequency in all three ethnic groups (13-50%), and its phylogenetic position, geographic distribution, and estimated age all support a recent origin, but without conclusively identifying a specific source region. Nevertheless, the haplotype's limited diversity, similar to those of other mtDNA haplogroups found in our Malagasy groups, best supports a small number of initial settlers arriving to Madagascar through the same migratory process. Finally, the discovery of this lineage provides a set of new polymorphic positions to help localize the Austronesian ancestors of the Malagasy, as well as uncover the origin and evolution of the Polynesian motif itself

Design of a retrospective patient record study on the occurrence of adverse events among patients in Dutch hospitals

BACKGROUND: Various international studies have shown that a substantial number of patients suffer from injuries or even die as a result of care delivered in hospitals. The occurrence of injuries among patients caused by health care management in Dutch hospitals has never been studied systematically. Therefore, an epidemiological study was initiated to determine the incidence, type and impact of adverse events among discharged and deceased patients in Dutch hospitals. METHODS/DESIGN: Three stage retrospective patient record review study in 21 hospitals of 8400 patient records of discharged or deceased patients in 2004. The records were reviewed by trained nurses and physicians between August 2005 and October 2006. In addition to the determination of presence, the degree of preventability, and causes of adverse events, also location, timing, classification, and most responsible specialty of the adverse events were measured. Moreover, patient and admission characteristics and the quality of the patient records were recorded. DISCUSSION: In this paper we report on the design of the retrospective patient record study on the occurrence of adverse events in Dutch hospitals. Attention is paid to the strengths and limitations of the study design. Furthermore, alterations made in the original research protocol in comparison with former international studies are described in detail

Chromoblastomycosis after a leech bite complicated by myiasis: a case report

Background Chromoblastomycosis is a chronic mycotic infection, most common in the tropics and subtropics, following traumatic fungal implantation. Case presentation A 72 year-old farmer was admitted to Luang Namtha Provincial Hospital, northern Laos, with a growth on the left lower leg which began 1 week after a forefoot leech bite 10 years previously. He presented with a cauliflower-like mass and plaque-like lesions on his lower leg/foot and cellulitis with a purulent tender swelling of his left heel. Twenty-two Chrysomya bezziana larvae were extracted from his heel. PCR of a biopsy of a left lower leg nodule demonstrated Fonsecaea pedrosoi, monophora, or F. nubica. He was successfully treated with long term terbinafin plus itraconazole pulse-therapy and local debridement. Conclusions Chromoblastomycosis is reported for the first time from Laos. It carries the danger of bacterial and myiasis superinfection. Leech bites may facilitate infection.This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited