2,153 research outputs found

    The Living Environmental Education

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    This open access book is designed and written to bridge the gap on the critical issues identified in environmental education programs in Asian countries. The world and its environments are changing rapidly, and the public may have difficulty keeping up and understanding how these changes will affect our way of life. The authors discuss various topics and case studies from an Asian perspective, but the content, messaging, and lessons learned need not be limited to Asian cultures. Each chapter provides a summary of the intensive research that has been performed on pro-environmental behaviors, the experience of people working in industry and at home, and their philosophies that guide them in their daily lives. We highlight humanity’s potential to contribute to Sustainable Development Goals (SDGs) by understanding better the environmental psychology, social inclusion, and environmental sustainability and stewardship protection elements that contribute to responsible environmental citizenship. The content of the chapters in this book includes a discussion of the crucial issues, plans, and evaluations for sustainability theories, practices, and actions with a proposed management structure for maximizing the cultural, social, and ecological diversity of Asian experiences compared to other theories and cultures internationally. We intend that the data in this book will provide a comprehensive guide for students, professors, practitioners, and entrepreneurs of environmental education and its related disciplines using case studies that demonstrate the relationship between the social and behavioral sciences and environmental leadership and sustainability

    The Living Environmental Education

    Get PDF
    This open access book is designed and written to bridge the gap on the critical issues identified in environmental education programs in Asian countries. The world and its environments are changing rapidly, and the public may have difficulty keeping up and understanding how these changes will affect our way of life. The authors discuss various topics and case studies from an Asian perspective, but the content, messaging, and lessons learned need not be limited to Asian cultures. Each chapter provides a summary of the intensive research that has been performed on pro-environmental behaviors, the experience of people working in industry and at home, and their philosophies that guide them in their daily lives. We highlight humanity’s potential to contribute to Sustainable Development Goals (SDGs) by understanding better the environmental psychology, social inclusion, and environmental sustainability and stewardship protection elements that contribute to responsible environmental citizenship. The content of the chapters in this book includes a discussion of the crucial issues, plans, and evaluations for sustainability theories, practices, and actions with a proposed management structure for maximizing the cultural, social, and ecological diversity of Asian experiences compared to other theories and cultures internationally. We intend that the data in this book will provide a comprehensive guide for students, professors, practitioners, and entrepreneurs of environmental education and its related disciplines using case studies that demonstrate the relationship between the social and behavioral sciences and environmental leadership and sustainability

    Expression of Estrogen Alpha and Beta Receptors in Prostate Cancer and Hyperplasia: Immunohistochemical Analysis

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    Objectives: Estrogen receptors are believed to play a significant role in the pathogenesis of prostate carcinoma (PCa). The aim of this study is to evaluate the expression of ER-α and ER-β in human benign and malignant prostatic tissue.Patients and Methods: The archival materials of 100 prostatic specimens (65 PCa, 35 BPH) were collected from the Department of Pathology, King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia. Seven PCa cases contained foci of high-grade prostate intraepithelial neoplasia (HGPIN). Immunohistochemistry was used to test the protein expression of ER-α and ER-β utilizing monoclonal mouse antihuman antibodies.Results: Among the 65 cases of PCa, ER-α was expressed in 3 cases (4.6%) in epithelial cells and 4 cases (6.1%) in stromal cells. ER-α was not expressed in any of the HGPIN foci. Additionally, ER-α was not expressed in either luminal or basal cells in any of the 35 BPH cases. However it was expressed in 4 cases (11.4%) in stromal cells of BPH. In PCa, ER-β was expressed in 61 cases (93.8%) and 35 cases (53.8%) in the epithelial and stromal cells respectively. ER-β was expressed only in 2 cases (28.5%) out of 7 HGPIN foci. It was expressed in 33 cases (94.3%) of epithelialand stromal cells of BPH. Conclusion: The majority of PCa and BPH exhibited nuclear immunoreactivity for ER-β in both tumor and stromal cells and they are usually negative for ER-α. There is probably partial loss of ER-β in HGPIN. ER-β may have a role in the process of prostatic hyperplasia and malignancy.Key Words: ER-α, ER-β, prostate, hyperplasia, premalignant, cancer,  immunohistochemistr

    Fractional extracts of Azadirachta indica leaf affect spermiogram, testosterone profile, and testis histology of rabbit bucks

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    The effect of fractions from a crude extract of Azadirachta indica leaves on spermatogenesis, testicular histology and testosterone concentration of New Zealand White rabbits were evaluated in this study. Twenty-five matured male New Zealand White rabbits were used for this study and were randomly assigned to five groups (A, B, C, D, and E). Group A served as the control and was administered distilled water (0.5ml); while groups B, C, D and E served as the hexane, chloroform, ethyl acetate, and butanol treated groups, respectively at the same dosage of 300 mg/kg. Semen samples were collected using an artificial vagina weekly for twelve weeks and were evaluated for volume, colour, motility, concentration, percentage live-dead ratio and morphological abnormalities. A blood sample (2ml) was also collected from each buck through venipuncture of the ear vein three times at regular intervals for the determination of testosterone concentration. Two bucks from each group were humanely sacrificed at the end of the experiment for testicular histology. Significantly lower (p<0.05) sperm motility, higher dead sperm cells, sperm abnormalities, degenerative changes, depletion and vacuolation of spermatogenic cell layers were observed in treatment group C at the end of the experiment. The present study has shown that the chloroform fraction of methanolic crude Azadirachta indica (neem) leaves extract is detrimental to sperm cells and testicular histology

    Cultural, morphological, pathogenic and molecular characterization of Alternaria mali associated with Alternaria leaf blotch of apple

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    Alternaria blotch (Alternaria mali) causes severe foliar damage to apple trees in Kashmir. Twenty one (21) isolates of A. mali were collected from different locations and characterized for cultural, morphological, pathogenic and molecular variations. A. mali colonies varied in their cultural behaviour ranging from velvety to cottony, mostly appressed, with regular to irregular margins. Colour of colonies ranged between light to dark olivacious. Isolates impregnated media with colour ranging between grey to brown. Growth rate of isolates was between 5.86 to 8.21 mm/day with fast growth in isolate Am-13 and least in Am-5. Morphological variations in size, shape and septation of hyphae, conidiophore and conidia were observed in the isolates with significant variations in conidiophore and conidial septation. Average conidial size ranged from 21.36 to 31.74 x 8.34 to 14.48 μm. Isolates exhibited variations in incubation period, number and size of the lesions were produced. The dendrogram analysis, based on cultural, morphological and pathogenic studies, revealed variation within A. mali population. At 67% similarity matrix, all the isolates formed 2 clusters with 12 and nine isolates in cluster I and II, respectively. However, dendrogram on molecular (random amplification of polymorphic DNA, RAPD) basis revealed five clusters at 68% Dice similarity coefficient. There was no congruence between RAPD pattern and cultural, morphological and pathogenic characters. Isolates identical for one spectrum were often dissimilar for other spectrum. The results demonstrate existence of considerable variation in cultural, morphological, pathogenic and molecular characters of A. mali isolates prevalent in Kashmir valley.Keywords: Apple, Alternaria mali, variability, cultural, morphological, pathogenic, RAPDAfrican Journal of Biotechnology Vol. 12(4), pp. 370-38

    Prevalence of hypertension in the rural adult population of Osun State, southwestern Nigeria

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    EO Asekun-Olarinmoye,1 PO Akinwusi,2 WO Adebimpe,1 MA Isawumi,3 MB Hassan,3 OA Olowe,4 OB Makanjuola,4 CO Alebiosu,2 TA Adewole51Department of Community Medicine, 2Department of Medicine, 3Department of Surgery, 4Department of Microbiology, 5Department of Chemical Pathology, College of Health Sciences, Osun State University, Osogbo, Osun State, NigeriaBackground: The purpose of this study was to determine the prevalence of hypertension in two rural communities of Osun State, Nigeria.Methods: A consenting adult population of the Alajue and Obokun rural communities in southwestern Nigeria that presented for the screening exercise participated in this community-based cross-sectional descriptive study. Two hundred and fifty-nine respondents aged older than 18 years completed a standardized, pretested, structured questionnaire as part of activities celebrating World Kidney Day and World Glaucoma Day in 2011. Anthropometric data and blood pressure were recorded, and the data were analyzed using the Statistical Package for Social Sciences version 17.Results: The mean age of the respondents was 49.7 &plusmn; 1.6 years, 100 (38.6%) were males, 84 (32.4%) were farmers, and 111 (42.9%) were traders. The prevalence of hypertension was 13.16% (present in 34 respondents). Seventeen (6.6%) had isolated systolic hypertension, while 11 (4.2%) had isolated diastolic hypertension. Two hundred and thirty-six (91.1%) undertook daily exercise lasting at least 30 minutes and 48 (18.5%) had ever taken antihypertensive drugs on a regular basis. Four respondents (1.6%) claimed a family history of hypertension. The average body mass index (BMI) among respondents was 23.4 &plusmn; 4.9 kg/m2, 51 (19.6%) had a BMI of 25.0&ndash;29.9, and 30 (11.5%) had a BMI &ge; 30. A significant association existed between age older than 40 years and having hypertension (P < 0.05), while no relationship existed between age and BMI or between gender and hypertension (P > 0.05). Rates of older age and high BMI were significantly higher among hypertensives than among normotensives. Respondents with BMI < 25 had at least a three times greater likelihood of developing hypertension than those with BMI < 25 (odds ratio 2.9, 95% confidence interval 0.007&ndash;0.056, P = 0.011).Conclusion: The prevalence of hypertension is high in this study population and we recommend scaling up primary prevention efforts to reduce this in Nigerian communities.Keywords: prevalence, hypertension, anthropometry, body mass index, rural communit

    ASCENT: A Context-Aware Spectrum Coexistence Design and Implementation Toolset for Policymakers in Satellite Bands

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    This paper introduces ASCENT (context Aware Spectrum Coexistence Design and Implementation) toolset, an advanced context-aware terrestrial satellite spectrum sharing toolset designed for researchers, policymakers, and regulators. It serves two essential purposes (a) evaluating the potential for harmful interference to primary users in satellite bands and (b) facilitating the analysis, design, and implementation of diverse regulatory policies on spectrum usage and sharing. Notably, ASCENT implements a closed-loop feedback system that allows dynamic adaptation of policies according to a wide range of contextual factors (e.g., weather, buildings, summer/winter foliage, etc.) and feedback on the impact of these policies through realistic simulation. Specifically, ASCENT comprises the following components (i) interference evaluation tool for evaluating interference at the incumbents in a spectrum-sharing environment while taking the underlying contexts, (ii) dynamic spectrum access (DSA) framework for providing context-aware instructions to adapt networking parameters and control secondary terrestrial network's access to the shared spectrum band according to context aware prioritization, (iii) Context broker to acquire essential and relevant contexts from external context information providers; and (iv) DSA Database to store dynamic and static contexts and the regulator's policy information. The closed-loop feedback system of ASCENT is implemented by integrating these components in a modular software architecture. A case study of sharing the lower 12 GHz Ku band (12.2-12.7 GHz) with the 5G terrestrial cellular network is considered, and the usability of ASCENT is demonstrated by dynamically changing exclusion zone's radius in different weather conditions

    Pattern of Respiratory Viruses among Pilgrims during 2019 Hajj Season Who Sought Healthcare Due to Severe Respiratory Symptoms

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    The aim of our study was to define the spectrum of viral infections in pilgrims with acute respiratory tract illnesses presenting to healthcare facilities around the holy places in Makkah, Saudi Arabia during the 2019 Hajj pilgrimage. During the five days of Hajj, a total of 185 pilgrims were enrolled in the study. Nasopharyngeal swabs (NPSs) of 126/185 patients (68.11%) tested positive for one or more respiratory viruses by PCR. Among the 126 pilgrims whose NPS were PCR positive: (a) there were 93/126 (74%) with a single virus infection, (b) 33/126 (26%) with coinfection with more than one virus (up to four viruses): of these, 25/33 cases had coinfection with two viruses; 6/33 were infected with three viruses, while the remaining 2/33 patients had infection with four viruses. Human rhinovirus (HRV) was the most common detected viruses with 53 cases (42.06%), followed by 27 (21.43%) cases of influenza A (H1N1), and 23 (18.25%) cases of influenza A other than H1N1. Twenty-five cases of CoV-229E (19.84%) were detected more than other coronavirus members (5 CoV-OC43 (3.97%), 4 CoV-HKU1 (3.17%), and 1 CoV-NL63 (0.79%)). PIV-3 was detected in 8 cases (6.35%). A single case (0.79%) of PIV-1 and PIV-4 were found. HMPV represented 5 (3.97%), RSV and influenza B 4 (3.17%) for each, and Parechovirus 1 (0.79%). Enterovirus, Bocavirus, and M. pneumoniae were not detected. Whether identification of viral nucleic acid represents nasopharyngeal carriage or specific causal etiology of RTI remains to be defined. Large controlled cohort studies (pre-Hajj, during Hajj, and post-Hajj) are required to define the carriage rates and the specific etiology and causal roles of specific individual viruses or combination of viruses in the pathogenesis of respiratory tract infections in pilgrims participating in the annual Hajj. Studies of the specific microbial etiology of respiratory track infections (RTIs) at mass gathering religious events remain a priority, especially in light of the novel SARS-CoV-2 pandemic

    The Making of a Mobile Caliphate State in the African Sahel

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    The goal of this chapter is to thoroughly understand the context of the dominant jihadist narratives and the nature of their appeal in the Sahelian region. All these jihadist ideologies are based on a peculiar Salafi Radicalism that aimed to transform the state and society by methods of preaching and violence. Therefore, studying and analyzing the principles of the Salafist discourse as a political project helps us to understand its points of strengths and weaknesses. In addition, we can be better look at the future trends and prospects of violent jihadist groups in the African Sahel. The roots of this Islamic discourse as a political project may be attributed to what Lunay and Suarez call the “Islamic domain.” The rise of violent radical Islamism represents drive from the internal political and socioeconomic dynamics evolving in each Sahelian state. However, the struggle and rivalry of jihadist ideologies after the military defeat of Daesh in Mosul is important at a time when thousands of fighters who have survived the civil wars in Iraq, Syria, and Libya are looking for new jihadist fields

    The effect of S-substitution at the O6-guanine site on the structure and dynamics of a DNA oligomer containing a G:T mismatch

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    The effect of S-substitution on the O6 guanine site of a 13-mer DNA duplex containing a G:T mismatch is studied using molecular dynamics. The structure, dynamic evolution and hydration of the S-substituted duplex are compared with those of a normal duplex, a duplex with Ssubstitution on guanine, but no mismatch and a duplex with just a G:T mismatch. The S-substituted mismatch leads to cell death rather than repair. One suggestion is that the G:T mismatch recognition protein recognises the S-substituted mismatch (GS:T) as G:T. This leads to a cycle of futile repair ending in DNA breakage and cell death. We find that some structural features of the helix are similar for the duplex with the G:T mismatch and that with the S-substituted mismatch, but differ from the normal duplex, notably the helical twist. These differences arise from the change in the hydrogen-bonding pattern of the base pair. However a marked feature of the S-substituted G:T mismatch duplex is a very large opening. This showed considerable variability. It is suggested that this enlarged opening would lend support to an alternative model of cell death in which the mismatch protein attaches to thioguanine and activates downstream damage-response pathways. Attack on the sulphur by reactive oxygen species, also leading to cell death, would also be aided by the large, variable opening
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