20,540 research outputs found
Relation between Tunneling and Particle Production in Vacuum Decay
The field-theoretical description of quantum fluctuations on the background
of a tunneling field is revisited in the case of a functional
Schrodinger approach. We apply this method in the case when quantum
fluctuations are coupled to the field through a mass-squared term,
which is 'time-dependent' since we include the dynamics of . The
resulting mode functions of the fluctuation field, which determine the quantum
state after tunneling, display a previously unseen resonance effect when their
mode number is comparable to the curvature scale of the bubble. A detailed
analysis of the relation between the excitations of the field about the true
vacuum (interpreted as particle creation) and the phase shift coming from
tunneling is presented.Comment: 20 pages, 4 figures, submitted to PR
Identifying Effective Behavior Change Techniques for Alcohol and Illicit Substance Use During Pregnancy: A Systematic Review.
Background: During pregnancy, consuming alcohol and using illicit drugs can have serious health implications for both mother and child. Behavioral change interventions, especially those underpinned by theoretical constructs, can be effective in reducing harmful substance use among pregnant women. Purpose: To understand what type of behavior change mechanisms could be useful in reducing alcohol consumption or achieving abstinence from illicit drug use during pregnancy, this review aimed to identify behavior change techniques (BCTs), the smallest, active components of interventions that may be effective. It also aimed to establish the extent that psychosocial-based theories were used to inform intervention design. Methods: To identify eligible randomized controlled trials (RCTs), five databases were searched electronically from the end search dates of the most recent Cochrane systematic reviews on behavioral interventions for each behavior, until March 2018. Within the RCTs, intervention descriptions were analyzed for BCT content and extent of theory use in the intervention design process and outcome measurements, in each trial, was established. "Effectiveness percentages," the number of times a BCT had been a component of an effective intervention divided by the total number of interventions it had been used in, were calculated for BCTs used in two or more trials. Results: Including all RCTs from the Cochrane reviews, and those published subsequently, nine alcohol and six illicit drug trials were identified. Interventions tested in four alcohol RCTs and no illicit drugs RCTs showed positive results. Subsequent data were extracted for alcohol consumption trials only. Thirteen BCTs showed "potential effectiveness" for alcohol consumption. Six of nine included alcohol trials reported using theory but not extensively. Conclusions: Action planning, behavioral contract, prompts/cues, self-talk, offer/direct toward written material, problem solving, feedback on behavior, social support (unspecified), information about health consequences, behavior substitution, assess current readiness and ability to reduce excess alcohol consumption, goal setting (behavior), and tailor interactions appropriately are BCTs that could be useful in helping reduce alcohol consumption among pregnant women
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Lipid and Protein Transfer between Nanolipoprotein Particles and Supported Lipid Bilayers.
A nanolipoprotein particle (NLP) is a lipid bilayer disc stabilized by two amphipathic "scaffold" apolipoproteins. It has been most notably utilized as a tool for solubilizing a variety of membrane proteins while preserving structural and functional properties. Transfer of functional proteins from NLPs into model membrane systems such as supported lipid bilayers (SLBs) would enable new opportunities, for example, two-dimensional protein crystallization and studies on protein-protein interactions. This work used fluorescence microscopy and atomic force microscopy to investigate the interaction between NLPs and SLBs. When incubated with SLBs, NLPs were found to spontaneously deliver lipid and protein cargo. The impact of membrane composition on lipid exchange was explored, revealing a positive correlation between the magnitude of lipid transfer and concentration of defects in the target SLB. Incorporation of lipids capable of binding specifically to polyhistidine tags encoded into the apolipoproteins also boosted transfer of NLP cargo. Optimal conditions for lipid and protein delivery from NLPs to SLBs are proposed based on interaction mechanisms
Minimal Potentials with Very Many Minima
We demonstrate, by construction, that simple renormalizable matrix potentials
with S_N, as opposed to O(N), symmetry can exhibit an exponentially large
number of inequivalent deep local minima.Comment: LaTeX, 9 pages, 2 figures. Additional applications and references
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Personhood, consciousness, and god : how to be a proper pantheist
© Springer Nature B.V. 2018In this paper I develop a theory of personhood which leaves open the possibility of construing the universe as a person. If successful, it removes one bar to endorsing pantheism. I do this by examining a rising school of thought on personhood, on which persons, or selves, are understood as identical to episodes of consciousness. Through a critique of this experiential approach to personhood, I develop a theory of self as constituted of qualitative mental contents, but where these contents are also capable of unconscious existence. On this theory, though we can be conscious of our selves, consciousness turns out to be inessential to personhood. This move, I then argue, provides resources for responding to the pantheist’s problem of God’s person.Peer reviewedFinal Accepted Versio
Physical activity as an aid to smoking cessation during pregnancy: Two feasibility studies
Background: Pharmacotherapies for smoking cessation have not been adequately tested in pregnancy and women are reluctant to use them. Behavioural support alone has a modest effect on cessation rates; therefore, more effective interventions are needed. Even moderate intensity physical activity (e.g. brisk walk) reduces urges to smoke and there is some evidence it increases cessation rates in non-pregnant smokers. Two pilot studies assessed i) the feasibility of recruiting pregnant women to a trial of physical activity for smoking cessation, ii) adherence to physical activity and iii) womens' perceptions of the
intervention.
Methods: Pregnant smokers volunteered for an intervention combining smoking cessation support, physical activity counselling and supervised exercise (e.g. treadmill walking). The first study provided six weekly treatment sessions. The second study provided 15 sessions over eight weeks. Physical activity levels and continuous smoking abstinence (verified by expired carbon monoxide) were monitored up to eight months gestation.
Results: Overall, 11.6% (32/277) of women recorded as smokers at their first antenatal booking visit were
recruited. At eight months gestation 25% (8/32) of the women achieved continuous smoking abstinence. Abstinent women attended at least 85% of treatment sessions and 75% (6/8) achieved the target level of 110 minutes/week of physical activity at end-of-treatment. Increased physical activity was maintained at eight months gestation only in the second study. Women reported that the intervention helped weight management, reduced cigarette cravings and increased confidence for quitting.
Conclusion: It is feasible to recruit pregnant smokers to a trial of physical activity for smoking cessation and this is likely to be popular. A large randomised controlled trial is needed to examine the efficacy of this intervention
Affordable Health Care Keeps Children and Families Healthy
The health of young children is negatively affected when parents have to forego health care for themselves or other adult members of the household or when parents have to forego payment of household expenses in order to pay for health care
Quantum critical behavior of electrons at the edge of charge order
We consider quantum critical points (QCP) in which quantum fluctuations
associated with charge rather than magnetic order induce unconventional
metallic properties. Based on finite-T calculations on a two-dimensional
extended Hubbard model we show how the coherence scale T* characteristic of
Fermi liquid behavior of the homogeneous metal vanishes at the onset of charge
order. A strong effective mass enhancement reminiscent of heavy fermion
behavior indicates the possible destruction of quasiparticles at the QCP.
Experimental probes on quarter-filled layered organic materials are proposed
for unveiling the behavior of electrons across the quantum critical region.Comment: 4 pages, 4 figures, accepted for publication in Phys. Rev. Let
MEDT 330 Clinical Laboratory Science: Medical Technology Practicum II
Course syllabus for MEDT 330 Clinical Laboratory Science: Medical Technology Practicum II
Course description: The student will review basic microbiology skills and perform identification of additional micro-organisms. The emphasis will be on gram negative enteric bacilli, non-fermentative gram negative bacilli and acid-fast bacilli. The identification and isolation of pathogenic organisms from clinical specimens will also be stressed
WIC Improves Child Health and School Readiness
New research by Children's HealthWatch demonstrates that young children who participate in the Special Supplemental Nutrition program for Women, Infants, and Children (WIC) are more likely to be in excellent or good health and have a reduced risk of developmental delay. Investing in WIC supports the nutritional and health needs of young children during a critical window of brain and body growth.Progam improvements that decrease access barriers, provide the full amount of fruits and vegetables recommended by the Institute of Medicine, and accommodate working parents' schedules will help young children reach their full potential
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