741 research outputs found

    Building an eScience Thesaurus for Librarians: A Collaboration Between the National Network of Libraries of Medicine, New England Region and an Associate Fellow at the National Library of Medicine

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    Objective: In response to the growing interest and adoption of eScience roles by librarians, those from the National Network of Libraries of Medicine, New England Region (NN/LM NER) and an Associate Fellow from the National Library of Medicine collaborated to build an eScience Thesaurus. The Thesaurus will introduce librarians to terminology and concepts in eScience, point to relevant literature and resources on data and digital research topics, and provide links to interviews with librarians and experts working in eScience-related roles. The eScience Thesaurus is a starting place for librarians to find the vocabulary to research the background, resources, and tools necessary for developing their capacity to provide eScience-related services. Methods: The Associate Fellow completed a review of eScience-related literature to identify the seminal publications for the originations of these terms and concepts as they apply to libraries. Next, the Associate Fellow worked with the NN/LM NER to compile an environmental scan of resources that would be useful and applicable for librarians, and created a scope document and record structure. The team interviewed prominent librarians working in eScience roles and experts that have created digital tools and services used by the library community. Finally, the team sent the Thesaurus records out to five members of the advisory and editorial review boards from the eScience Portal for New England Librarians for evaluation. Results: The eScience Thesaurus is now hosted on the eScience Portal for New England Librarians’ website. It provides a comprehensive list of more than 50 different terminologies and concepts, with links to seminal and relevant literature, resources, grants, and interviews on a variety of eScience-related topics. Conclusion: The eScience Thesaurus is an evolving resource; as the field expands and more eScience-related terms are adopted by the library and information science community, the Portal will enable its users to electronically submit new vocabulary and records to the Thesuarus, thus preserving it as a go-to eScience resource for librarians

    Collaborative Assessment and Survey Administration: A MISO Survey Case Study

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    The Managing Information Services Outcomes (MISO) Survey was originally developed in 2005 at Bryn Mawr College in Pennsylvania, USA by staff from a consortium of higher education institutions to assess library and technology services using a single instrument. Since then, the survey has grown and changed under the collaborative management of an all-volunteer team of library and IT professionals from various participating institutions throughout the United States. The survey has been implemented at 171 institutions. This chapter reviews the guiding principles, ongoing partnerships, and the value of working across departments, across campuses, and across cohorts of participating institutions to leverage local expertise, reduce costs, and create a culture of collaboration and assessment. In an environment where libraries are increasingly dependent on information technology, assessing library services in the context of IT brings layered intelligence to data-informed decision making. -- Chapter 9, p. 17

    Geometry and symmetry presculpt the free-energy landscape of proteins

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    We present a simple physical model which demonstrates that the native state folds of proteins can emerge on the basis of considerations of geometry and symmetry. We show that the inherent anisotropy of a chain molecule, the geometrical and energetic constraints placed by the hydrogen bonds and sterics, and hydrophobicity are sufficient to yield a free energy landscape with broad minima even for a homopolymer. These minima correspond to marginally compact structures comprising the menu of folds that proteins choose from to house their native-states in. Our results provide a general framework for understanding the common characteristics of globular proteins.Comment: 23 pages, 5 figure

    Universal correlations of trapped one-dimensional impenetrable bosons

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    We calculate the asymptotic behaviour of the one body density matrix of one-dimensional impenetrable bosons in finite size geometries. Our approach is based on a modification of the Replica Method from the theory of disordered systems. We obtain explicit expressions for oscillating terms, similar to fermionic Friedel oscillations. These terms are universal and originate from the strong short-range correlations between bosons in one dimension.Comment: 18 pages, 3 figures. Published versio

    A multicentre retrospective cohort comparison of aetiology and survival in patients with chronic hypersensitivity pneumonitis versus idiopathic pulmonary fibrosis

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    This is the author accepted manuscript. The final version is available from BMJ Publishing Group via the DOI in this recordWinter Meeting of the British Thoracic Society, 5-7 December 2018, London, U

    Early Service leavers: a study of the factors associated with premature separation from the UK Armed Forces and the mental health of those that leave early.

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    BACKGROUND: Approximately 18,000 personnel leave the UK Armed Forces annually. Those leaving before completing the minimum term of their contracts are called early Service leavers (ESLs). This study aims to identify characteristics associated with being an ESL, and compare the post-discharge mental health of ESLs and other Service leavers (non-ESLs). METHOD: A cross-sectional study used data on ex-Serving UK Armed Forces personnel. ESLs were personnel leaving before completing their 3-4.5 years minimum Service contracts and were compared with non-ESLs. Multivariable logistic regression was used to estimate odds ratios and 95% confidence intervals for the associations between Service leaving status with socio-demographics, military characteristics and mental health outcomes. RESULTS: Of 845 Service leavers, 80 (9.5%) were ESLs. Being an ESL was associated with younger age, female sex, not being in a relationship, lower rank, serving in the Army and with a trend of reporting higher levels of childhood adversity, but not with deployment to Iraq. ESLs were at an increased risk of probable post-traumatic stress disorder (PTSD), common mental disorders, fatigue and multiple physical symptoms, but not alcohol misuse. CONCLUSIONS: The study suggests that operational Service is not a factor causing personnel to become an ESL. Current mental health problems were more commonly reported among ESLs than other Service leavers. There may be a need to target interventions to ESLs on leaving Service to smooth their transition to civilian life and prevent the negative mental health outcomes experienced by ESLs further down the line

    Partisan Asymmetries in Online Political Activity

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    We examine partisan differences in the behavior, communication patterns and social interactions of more than 18,000 politically-active Twitter users to produce evidence that points to changing levels of partisan engagement with the American online political landscape. Analysis of a network defined by the communication activity of these users in proximity to the 2010 midterm congressional elections reveals a highly segregated, well clustered partisan community structure. Using cluster membership as a high-fidelity (87% accuracy) proxy for political affiliation, we characterize a wide range of differences in the behavior, communication and social connectivity of left- and right-leaning Twitter users. We find that in contrast to the online political dynamics of the 2008 campaign, right-leaning Twitter users exhibit greater levels of political activity, a more tightly interconnected social structure, and a communication network topology that facilitates the rapid and broad dissemination of political information.Comment: 17 pages, 10 figures, 6 table

    Leaning in to Address Sleep Disturbances and Sleep Disorders in Department of Defense and Defense Health Agency

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    Letter to the Editor, Military Medicine, 187, 5/6:155, 202217 USC 105 interim-entered record; under review.The article of record as published may be found at http://dx.doi.org/10.1177/0018720820906050In their article entitled, “Engaging Stakeholders to Optimize Sleep Disorders Management in the U.S. Military: A Qualitative Analysis,” Abdelwadoud and colleagues conducted focus groups of service members, primary care managers (PCMs), and administrative stakeholders about their perceptions, experiences, roles in sleep management, stated education needs, and management of sleep disorders.1 The qualitative methods are rigorous, and the findings reinforce and nuance prior results, especially regarding key requirements from PCMs. We feel compelled, however, to further nuance the authors’ conclusion that “current military sleep management practices are neither satisfactory nor maximally effective” and offer specific examples of actions taken by the Department of Defense (DoD) and Defense Health Agency (DHA) in recognition of the significance of optimal sleep in combat readiness and overall health of service members. We offer here a succinct list of concrete efforts to support and implement substantial clinical, operational, research, or educational efforts by the DoD or DHA to improve sleep in service members and associated clinical challenges in this unique population.Identified in text as U.S. Government work

    Mite community composition across a European transect and its relationships to variation in other components of soil biodiversity

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    The sustainable use of soils requires the protection of soil biodiversity because of its importance in the delivery of ecosystems services. However, no effective indicator exists which would allow assessment of the current state of biodiversity and is sensitive to change. This study, which is a component of the EcoFINDERS project, examines the use of mites (Acari) as a possible biological indicator of soil community composition. Thirty-six sites were sampled across 10 European countries spanning four bio-climatic zones (Alpine, Atlantic, Continental and Mediterranean) and 3 land uses (arable, grassland and forestry) for both biotic and abiotic variables. Results show a significant effect of bio-climatic zone on mite communities; in particular, the Mediterranean region had a rather distinct composition. Land use type significantly affected mite community composition and there was a distinct association with forestry. Cross-taxon congruence among soil taxa was variable and generally weak. Procrustes analysis showed that there was little similarity between the patterns of variation in mite community composition and those of other taxonomic groups (Collembola, Enchytraeidae, Nematoda and microbes). Mite and Collembola communities had the strongest correlation ( r= 0.4316, p</p
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