Spectroscopic characterization of X-ray emitting young stars associated with the Sh 2-296 nebula

We studied a sample of stars associated with the Sh 2-296 nebula, part of the reflection nebulae complex in the region of Canis Major (CMa R1). Our sample corresponds to optical counterparts of X-ray sources detected from observations with the XMM-Newton satellite, which revealed dozens of possible low-mass young stars not yet known in this region. A sample of 58 young star candidates were selected based on optical spectral features, mainly H{\alpha} and lithium lines, observed with multi-objects spectroscopy performed by the Gemini South telescope. Among the candidates, we find 41 confirmed T Tauri and 15 very likely young stars. Based on the H{\alpha} emission, the T Tauri stars were distinguished between classical (17%) and weak-lined (83%), but no significant difference was found in the age and mass distribution of these two classes. The characterization of the sample was complemented by near- and mid-infrared data, providing an estimate of ages and masses from the comparison with pre-main-sequence evolutionary models. While half of the young stars have an age of 1-2 Myrs or less, only a small fraction (~25%) shows evidence of IR excess revealing the presence of circumstellar discs. This low fraction is quite rare compared to most young star-forming regions, suggesting that some external factor has accelerated the disc dissipation

Star formation history of Canis Major OB1 - II. A bimodal X-ray population revealed by XMM-Newton

The Canis Major OB1 Association has an intriguing scenario of star formation, especially in the Canis Major R1 (CMa R1) region traditionally assigned to a reflection nebula, but in reality an ionized region. This work is focused on the young stellar population associated to CMa R1, for which our previous results from ROSAT, optical and near-infrared data had revealed two stellar groups with different ages, suggesting a possible mixing of populations originated from distinct star-formation episodes. The X-ray data allow the detected sources to be characterized according to hardness ratios, light curves and spectra. Estimates of mass and age were obtained from the 2MASS catalogue, and used to define a complete subsample of stellar counterparts, for statistical purposes. A catalogue of 387 XMM-Newton sources is provided, 78% being confirmed as members or probable members of the CMa R1 association. Flares were observed for 13 sources, and the spectra of 21 bright sources could be fitted by a thermal plasma model. Mean values of fits parameters were used to estimate X-ray luminosities. We found a minimum value of log(L$_X$[erg/s]) = 29.43, indicating that our sample of low-mass stars (M$_\star$ $\leq$ 0.5 M$_\odot$), being faint X-ray emitters, is incomplete. Among the 250 objects selected as our complete subsample (defining our best sample), 171 are found to the East of the cloud, near Z CMa and dense molecular gas, 50% of them being young ( 10 Myr). The opposite happens to the West, near GU CMa, in areas lacking molecular gas: among 79 objects, 30% are young and 50% are older. These findings confirm that a first episode of distributed star formation occurred in the whole studied region ~10 Myr ago and dispersed the molecular gas, while a second, localized episode (< 5 Myr) took place in the regions where molecular gas is still present.Comment: 38 pages, 21 figures, accepted for A&

Automatic identification of gait events using an instrumented sock

Background: textile-based transducers are an emerging technology in which piezo-resistive properties of materials are used to measure an applied strain. By incorporating these sensors into a sock, this technology offers the potential to detect critical events during the stance phase of the gait cycle. This could prove useful in several applications, such as functional electrical stimulation (FES) systems to assist gait. Methods: we investigated the output of a knitted resistive strain sensor during walking and sought to determine the degree of similarity between the sensor output and the ankle angle in the sagittal plane. In addition, we investigated whether it would be possible to predict three key gait events, heel strike, heel lift and toe off, with a relatively straight-forward algorithm. This worked by predicting gait events to occur at fixed time offsets from specific peaks in the sensor signal. Results: our results showed that, for all subjects, the sensor output exhibited the same general characteristics as the ankle joint angle. However, there were large between-subjects differences in the degree of similarity between the two curves. Despite this variability, it was possible to accurately predict gait events using a simple algorithm. This algorithm displayed high levels of trial-to-trial repeatability. Conclusions: this study demonstrates the potential of using textile-based transducers in future devices that provide active gait assistance

Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms

Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable mechanisms of response. The present study aimed to assess whether environmental trace concentrations of TAM are bioavailable to the filter feeder M. galloprovincialis (100 ng L-1) and to the deposit feeder N. diversicolor (0.5, 10, 25 and 100 ng L-1) after 14 days of exposure. Behavioural impairment (burrowing kinetic), neurotoxicity (AChE activity), endocrine disruption by alkali-labile phosphate (ALP) content, oxidative stress (SOD, CAT, GPXs activities), biotransformation (GST activity), oxidative damage (LPO) and genotoxicity (DNA damage) were assessed. Moreover, this study also pertained to compare TAM cytotoxicity effects to mussels and targeted human (i.e. immortalized retinal pigment epithelium - RPE; and human transformed endothelial cells - HeLa) cell lines, in a range of concentrations from 0.5 ng L-1 to 50 μg L-1. In polychaetes N. diversicolor, TAM exerted remarkable oxidative stress and damage at the lowest concentration (0.5 ng L-1), whereas significant genotoxicity was reported at the highest exposure level (100 ng L-1). In mussels M. galloprovincialis, 100 ng L-1 TAM caused endocrine disruption in males, neurotoxicity, and an induction in GST activity and LPO byproducts in gills, corroborating in genotoxicity over the exposure days. Although cytotoxicity assays conducted with mussel haemocytes following in vivo exposure was not effective, in vitro exposure showed to be a feasible alternative, with comparable sensitivity to human cell line (HeLa).info:eu-repo/semantics/publishedVersio