MODLEACH: A Variant of LEACH for WSNs

Wireless sensor networks are appearing as an emerging need for mankind. Though, Such networks are still in research phase however, they have high potential to be applied in almost every field of life. Lots of research is done and a lot more is awaiting to be standardized. In this work, cluster based routing in wireless sensor networks is studied precisely. Further, we modify one of the most prominent wireless sensor network's routing protocol "LEACH" as modified LEACH (MODLEACH) by introducing \emph{efficient cluster head replacement scheme} and \emph{dual transmitting power levels}. Our modified LEACH, in comparison with LEACH out performs it using metrics of cluster head formation, through put and network life. Afterwards, hard and soft thresholds are implemented on modified LEACH (MODLEACH) that boast the performance even more. Finally a brief performance analysis of LEACH, Modified LEACH (MODLEACH), MODLEACH with hard threshold (MODLEACHHT) and MODLEACH with soft threshold (MODLEACHST) is undertaken considering metrics of throughput, network life and cluster head replacements.Comment: IEEE 8th International Conference on Broadband and Wireless Computing, Communication and Applications (BWCCA'13), Compiegne, Franc

Clinical trial: protective effect of a commercial fish protein hydrolysate against indomethacin (NSAID)-induced small intestinal injury

Background A partially hydrolysed and dried product of pacific whiting fish is marketed as a health food supplement supporting 'intestinal health'.Aim To examine whether the partially hydrolysed and dried product of pacific whiting fish influenced the small intestinal damaging side effects of the nonsteroidal anti-inflammatory drug, indomethacin.Methods Eight human volunteers completed a double-blind, placebo-controlled, crossover protocol of clinically relevant dose of indomethacin (50 mg t.d.s. p.o. for 5 days) with 7 days of fish hydrolysate or placebo starting 2 days prior to indomethacin. Changes in gut permeability were assessed using 5 h urinary lactulose:rhamnose (L/R) ratios.Results Fish hydrolysate given alone did not affect permeability. In the main study (n = 8), baseline values were similar for both arms (0.28 +/- 0.05 and 0.35 +/- 0.07). Administration of indomethacin (+placebo) caused a fivefold rise in L/R ratios (increasing to 1.54 +/- 0.35), whereas L/R ratios in the same subjects ingesting indomethacin + fish hydrolysate was only 0.59 +/- 0.14 (P < 0.01 vs. indomethacin alone). Dyspeptic symptoms occurred in four of eight subjects taking indomethacin alone, but zero of eight when hydrolysate was co-administered.Conclusion Natural bioactive products (nutriceuticals), such as fish hydrolysates, may provide a novel approach to the prevention and treatment of NSAID-induced and other gastrointestinal injurious conditions

Influence of Natural Fibers on the Performance of Hot Mix Asphalt for the Wearing Course of Pavement

Cracking in the flexible pavement is a serious problem that reduces the service life of the roads pavement unless they are treated with great care. Since flexible pavement is very weaker in tension than in compression, it is usually necessary to consider the tensile stresses and some type of additives to improve asphaltpavement performance, and one of the most effective ways of improving asphalt pavement performance is to reinforce asphalt mixtures by incorporating natural fibers. The main objective of this study is to use palm fiber, which is locally available, in hot mix asphalt mixtures. To achieve this objective, the Marshall test and indirect tensile strength test were conducted on four asphalt mixtures with different types of natural fibers (Coconut, Corn, Palm, and Sisal), added in varying percentages 0.1, 0.2, 0.3, 0.4, and 0.5% and different lengths of fiber 0.5, 1, 1.5, and 2 cm. Based on the analyzed results, it can be concluded that the use of palm fiber increased the Marshall stability by 20% as compared with the conventional mixture and raised up the retained tensile strength ratio up to 92%. Finally, the use of 0.2% content of natural fiber at 1.5 cm length gave a better performance for the mixtures

Choosing Solitude: Age Differences in Situational and Affective Correlates of Solitude-Seeking in Midlife and Older Adulthood

This is the author accepted manuscript. The final version is available from Oxford University Press via the DOI in this record.Objectives Despite a basic need for social connection, individuals across the adult lifespan sometimes seek solitude—a phenomenon that is not well understood. This study examined situational and affective correlates of solitude-seeking and how they may differ between middle-aged and older adults. Method One hundred community-dwelling adults aged 50–85 years (64% female, 56% East Asian, 36% European, 8% other) completed approximately 30 electronic daily life assessments over 10 days regarding their current location, affect, activities, and current and desired social context. Results Solitude was common; 86% of solitude instances happened by individuals’ own choosing. When desiring solitude, older adults were more likely to be at home and less likely to be outdoors, compared to other locations. Middle-aged adults showed no such solitude-location associations. Among middle-aged adults, desire for solitude was associated with decreased positive affect. Older adults experienced no such dip in affect. Discussion Findings suggest that compared to middle-aged adults, older adults are more likely to go to locations that match their desired social context, and also that solitude-seeking has more positive ramifications for older adults. Findings are discussed in the context of age differences in activities, social preferences, and emotion regulation.Vancouver FoundationUniversity of British Columbia Faculty of ArtsMichael Smith FoundationSocial Sciences and Humanities Research Council of Canad

Diferuloylmethane anchored anatase TiO2 nanoparticle for dye sensitized solar cell

Dye sensitized solar cells (DSSC) have been constructed by using diferuloylmethane dye as natural photosensitizers for anatase nanostructure TiO2 thin film coated on FTO conductive glass substrate. Structural and morphological properties of the semiconductor films have been characterized by X-ray diffractometer and scanning electron microscopy, respectively, as well as, the wavelength of the maximum absorbance of the dye anchored on TiO2 film has been studied by using UV-Vis spectrophotometer. The XRD pattern of TiO2 thin films made by Doctor-blading deposition technique has revealed that the grain size of TiO2 is equal to 40 nm. The photovoltaic performance of the cells have been investigated in terms of power conversion efficiency, furthermore the effect of different spectroscopic parameters on the PV performance of constructed DSSC has been studied

Bacterial ventriculoperitoneal shunt infections: changing trends in antimicrobial susceptibility, a 7-year retrospective study from Pakistan

BACKGROUND: Ventriculoperitoneal (VP) shunt infections in adults represent a severe complication and make treatment more challenging. Therefore, drug susceptibility patterns are crucial for therapeutic decisions and infection control in neurosurgical centers. This 7-year retrospective study aimed to identify the bacteria responsible for adult VP shunt infections and determine their drug susceptibility patterns. METHODS: This single-center study was performed from 2015 to 2021 in Lahore, Pakistan, and included CSF cultures from VP shunt infections. Demographic data, causative organisms, and antimicrobial susceptibility testing results were collected. Multivariate analysis of variance (MANOVA) and two-sample t-tests were used to analyze and compare the antibiotic sensitivity trends over the study period. RESULTS: 14,473 isolates recovered from 13,937 CSF samples of VP shunt infections were identified and analyzed for their susceptibility patterns to antimicrobials. The proportion of Gram-negative and Gram-positive bacteria were 11,030 (76%) and 3443 (24)%, respectively. The predominant bacteria were Acinetobacter species (n = 5898, 41%), followed by Pseudomonas species (n = 2368, 16%) and coagulase-negative Staphylococcus (CoNS) (n = 1880, 13%). 100% of Staphylococcus aureus (S.aureus) and CoNS were sensitive to vancomycin and linezolid (n = 2580). However, 52% of S. aureus (719/1,343) were methicillin-resistant Staphylococcus aureus (MRSA). Acinetobacter showed maximum sensitivity to meropenem at 69% (2759/4768). Pseudomonas was 80% (1385/1863 sensitive to piperacillin-tazobactam, Escherichia coli (E. coli) showed 72% to amikacin (748/1055), while Klebsiella spp. was 57% (574/1170) sensitive to piperacillin-tazobactam. The sensitivity of piperacillin-tazobactam and meropenem for Gram-negative bacteria decreased significantly (p < 0.05) over 7 years, with 92.2% and 88.91% sensitive in 2015 and 66.7% and 62.8% sensitive in 2021, respectively. CONCLUSION: The significant decrease in the effectiveness of carbapenem and beta-lactam/beta-lactamase inhibitor combination drugs for the common Gram-negative causative agents of VP shunt infections suggests that alternative antibiotics such as colistin, fosfomycin, ceftazidime/avibactam, ceftolozane/tazobactam, and tigecycline should be considered and in consequence included in testing panels. Additionally, it is recommended to adopt care bundles for the prevention of VP shunt infection

Propagation of Light in Photonic Crystal Fibre Devices

We describe a semi-analytical approach for three-dimensional analysis of photonic crystal fibre devices. The approach relies on modal transmission-line theory. We offer two examples illustrating the utilization of this approach in photonic crystal fibres: the verification of the coupling action in a photonic crystal fibre coupler and the modal reflectivity in a photonic crystal fibre distributed Bragg reflector.Comment: 15 pages including 7 figures. Accepted for J. Opt. A: Pure Appl. Op

Exploring cucumber extract for skin rejuvenation

This study was designed to develop a topical skin-care cream water in oil (w/o) emulsion of 3% cucumber extracts versus its vehicle (Base) as control and evaluates its effects on skin-melanin, skin erythema, skin moisture, skin sebum and transepidermal water loss (TEWL).  Hydroalcohol.c cucumber (Cucumis sativus) fruit extract was entrapped in the inner aqueous phase of w/o emulsion. Base containing no extract and a formulation containing 3% concentrated extract of C. sativus was formulated. The odour was adjusted with few drops of lemon oil. Both the base and formulation were stored at different storage conditions for a period of 4 weeks to predict their stability. Different stability parameters that is: Physical stability, centrifugation and pH were monitored at different time intervals. Both the base and formulation were applied to the cheeks of 21 healthy human volunteers for a period of 4 weeks. The expected pharmaceutical stability of creams was achieved from 4 weeks in vitro study period. Odour disappeared with passage of time due to volatilization of lemon oil. The base showed insignificant (p &gt; 0.05) effects on all skin parameters except sebum that was not significant, whereas the formulation showed statistically significant (p.0.05) effects on skin sebum secretion. TEWL and erythema was increased while skin melanin and skin hydration level was decreased by formulation. However these effects were statistically insignificant (p &gt; 0.05). The results showed a good stability over 4 weeks of observation period of both base and formulation and the formulation has anti sebum secretion, bleaching and moisturizing effects.Key words: Cucumber extract, melanin, skin moisture, skin sebum, transepidermal water loss (TEWL)

The Book of Acoustics

The Book of Acoustics was created in collaboration with leading acousticians, neuroscientists and designers. It explores the science of sound and provides guidance for designing with acoustics. Complete with facts, figures, diagrams and expert insight, it is the ideal starting point for architectural and interior design projects and sheds light on the interplay between engineering and aesthetics