APPLICATION OF MANAGEMENT PROGRAMS FOR CHRONIC DISEASES - INTERNATIONAL EXPERIENCE AND SITUATION IN BULGARIA

Disease management programs (DMPs) are successful in different regions of the world and there are possibilities for their application in Bulgaria. A retrospective approach is used in the analysis of 11 articles, for the period 2002 – 2011. The data shows that the disease management programs improve the coordination between the different participants in the system and ensure comprehensiveness and continuity of the health care and, at the same time, early diagnostics, therapy and rehabilitation.Disease management programs (DMPs) are successful in different regions of the world and there are possibilities for their application in Bulgaria. A retrospective approach is used in the analysis of 11 articles, for the period 2002 – 2011. The data shows that the disease management programs improve the coordination between the different participants in the system and ensure comprehensiveness and continuity of the health care and, at the same time, early diagnostics, therapy and rehabilitation

Instability in a non-ohmic/ohmic fluid interface under a perpendicular electric field and unipolar injection

We set the equations for the linear electrohydrodynamic instability of an interface between two fluids, subjected to a perpendicular field and a unipolar charge injection. One of the fluids is modeled as being in non-ohmic regime (insulating), whereas the other is ohmic. A new interfacial instability mechanism is described, which may account for the Rose-window instability. The equations are analytically solved in the limit of long wavelength and neglecting the fluid motion. We show that this limit applies well to the case of an air-ohmic liquid interface. The applicability to a liquid-liquid interface is also analyzed

Mobile Medicine and General Trends in Medical Informatics

New challenges in medicine gained systemic character along with the accumulation of new data on links between functional units in human body; most of them, starting from the genetic level, are able to impact different disciplines at some earlier unimaginable stages of their development. That is why a counterpart activity, which is purposed to vanquish them, must also have a systemic character. With this respect, medical informatics (MI) is the first line reserve among others. From MI we get the most explicit response to urgent demands in health care via constructive multidisciplinary dialogue]. MI contributes to all medical disciplines; its development led to newest concepts such as personalized medicine, m-health, evidence-based medicine, etc

Проепілептогенний ефект наночастинок срібла на моделі пентиленететразол-індукованого кіндлінгу

On the model of pentylenetetrazol (PTZ)-induced kindling in Wistar rats the net reduction of ED50 dosage of PTZ, which was able to induce clonic seizures in 50% of experimental animals caused by silver nanoparticles was established. This effect was more pronounced in postponed period of kindling and was followed by intensification of electrographic epileptiform manifestations. Silver argentum nanoparticles influence on chronic seizure activity was determined in conditions of chronic experiment. Authors concluded that argentum nanoparticles are responsible for seizure activity enhancening.На моделі пентиленететразол (ПТЗ)-індукованого кіндлінгу у щурів лінії Вістар показано зниження середньоефективної дози ПТЗ, що викликає клонічні судоми у 50 % щурів під впливом системного застосування наночастинок срібла. Даний ефект був більш вираженим у віддаленому періоді кіндлінгу й супроводжувався посиленням електрографічних епілептиформних проявів. За умов хронічного експерименту проводили досліди із визначення впливу наночастинок срібла на вираженість хронічної судомної активності. Автори висловлюють думку, що підсилення інтенсивності судомної активності відбувається завдяки придатності наночастинок срібла

How Does Investors' Legal Protection Affect Productivity and Growth?

This paper analyzes the implications of investors' legal protection on aggregate productivity and growth. We have two main results. First, that better investors' legal protection can mitigate agency problems between investors and innovators and therefore expand the range of high-tech projects that can be financed by non-bank investors. Second, investors' legal protection shifts investment resources from less productive (medium-tech) to highly productive (high-tech) projects and therefore enhances economic growth. These results stem from two forces. On one hand, private investors' moral hazard problems (in which entrepreneurs shift investors' resources to their own benefit), and on the other hand innovators' risk of project termination by banks due to wrong signals about projects' probability of success. Our results are consistent with recent empirical studies that show a high correlation between legal investors' protection and the structure of the financial system as well as the economic performance at industry and macroeconomic levels