3,789 research outputs found
A new sound mode in liquid Helium 4?
This letter is based on the hypothesis of a small entropy content of the
superfluid fraction of liquid helium. We show that such a superfluid entropy
gives rise to a new sound mode in a ring-shaped superleak. This mode is named
sixth sound. We propose an experiment by which its sound velocity and thereby
the superfluid entropy can be measured. A negative experiment would yield a new
upper limit for the superfluid entropy.Comment: 9 pages, latex, published in Phys. Lett. A 187 (1994) 8
A Role for Actin, Cdc1p, and Myo2p in the Inheritance of Late Golgi Elements in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e
In Saccharomyces cerevisiae, Golgi elements are present in the bud very early in the cell cycle. We have analyzed this Golgi inheritance process using fluorescence microscopy and genetics. In rapidly growing cells, late Golgi elements show an actin-dependent concentration at sites of polarized growth. Late Golgi elements are apparently transported into the bud along actin cables and are also retained in the bud by a mechanism that may involve actin. A visual screen for mutants defective in the inheritance of late Golgi elements yielded multiple alleles of CDC1. Mutations in CDC1 severely depolarize the actin cytoskeleton, and these mutations prevent late Golgi elements from being retained in the bud. The efficient localization of late Golgi elements to the bud requires the type V myosin Myo2p, further suggesting that actin plays a role in Golgi inheritance. Surprisingly, early and late Golgi elements are inherited by different pathways, with early Golgi elements localizing to the bud in a Cdc1p- and Myo2p-independent manner. We propose that early Golgi elements arise from ER membranes that are present in the bud. These two pathways of Golgi inheritance in S. cerevisiae resemble Golgi inheritance pathways in vertebrate cells
The two-fluid model with superfluid entropy
The two-fluid model of liquid helium is generalized to the case that the
superfluid fraction has a small entropy content. We present theoretical
arguments in favour of such a small superfluid entropy. In the generalized
two-fluid model various sound modes of HeII are investigated. In a
superleak carrying a persistent current the superfluid entropy leads to a new
sound mode which we call sixth sound. The relation between the sixth sound and
the superfluid entropy is discussed in detail.Comment: 22 pages, latex, published in Nuovo Cimento 16 D (1994) 37
Incorporation of alkylthiol chains at C-5 of deoxyuridine
A series of alkylthiol-tether homologs at C-5 of 2'-deoxyuridine have been synthesized and incorporated into DNA oligomers through solid-phase DNA phosphoramidite synthesis. DNA-ligand disulfide crosslinks have been initially addressed through formation of an n-butyl-DNA disulfide conjugate.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/30630/1/0000271.pd
Advancing oral medicine through informatics and information technology: a proposed framework and strategy.
The implementation of information technology in healthcare is a significant focus for many nations around the world. However, information technology support for clinical care, research and education in oral medicine is currently poorly developed. This situation hampers our ability to transform oral medicine into a 'learning healthcare discipline' in which the divide between clinical practice and research is diminished and, ultimately, eliminated. This paper reviews the needs of and requirements for information technology support of oral medicine and proposes an agenda designed to meet those needs. For oral medicine, this agenda includes analyzing and reviewing current clinical and documentation practices, working toward progressively standardizing clinical data, and helping define requirements for oral medicine systems. IT professionals can contribute by conducting baseline studies about the use of electronic systems, helping develop controlled vocabularies and ontologies, and designing, implementing, and evaluating novel systems centered on the needs of clinicians, researchers and educators. Successfully advancing IT support for oral medicine will require close coordination and collaboration among oral medicine professionals, information technology professionals, system vendors, and funding agencies. If current barriers and obstacles are overcome, practice and research in oral medicine stand ready to derive significant benefits from the application of information technology
Top Management Team Diversity: A systematic Review
Empirical research investigating the impact of top management team (TMT)
diversity on executives’ decision making has produced inconclusive results.
To synthesize and aggregate the results on the diversity-performance
link, a meta-regression analysis (MRA) is conducted. It integrates more
than 200 estimates from 53 empirical studies investigating TMT diversity
and its impact on the quality of executives’ decision making as reflected
in corporate performance. The analysis contributes to the literature by
theoretically discussing and empirically examining the effects of TMT diversity
on corporate performance. Our results do not show a link between TMT
diversity and performance but provide evidence for publication bias. Thus,
the findings raise doubts on the impact of TMT diversity on performance
Political institutions and debt crises
This paper shows that political institutions matter in explaining defaults on external and domestic debt obligations. We explore a large number of political and macroeconomic variables using a non-parametric technique to predict safety from default. The advantage of this technique is that it is able to identify patterns in the data that are not captured in standard probit analysis. We find that political factors matter, and do so in different ways for democratic and non-democratic regimes, and for domestic and external debt. In democracies, a parliamentary system or sufficient checks and balances almost guarantee the absence of default on external debt when economic fundamentals or liquidity are sufficiently strong. In dictatorships, high stability and tenure play a similar role for default on domestic debt
Plant Growth Promotion, Phytohormone Production and Genomics of the Rhizosphere-Associated Microalga, Micractinium rhizosphaerae sp. nov.
Funding Information: This work was funded by Fundação para a Ciência e Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020) and the Associate Laboratory LS4FUTURE (LA/P/0087/2020). Funding Information: F.Q.-N. and P.R.B. acknowledge receiving a PhD fellowship from FCT (2022.10633.BD; 2021.07927.BD514, respectively). Publisher Copyright: © 2023 by the authors.Microalgae are important members of the soil and plant microbiomes, playing key roles in the maintenance of soil and plant health as well as in the promotion of plant growth. However, not much is understood regarding the potential of different microalgae strains in augmenting plant growth, or the mechanisms involved in such activities. In this work, the functional and genomic characterization of strain NFX-FRZ, a eukaryotic microalga belonging to the Micractinium genus that was isolated from the rhizosphere of a plant growing in a natural environment in Portugal, is presented and analyzed. The results obtained demonstrate that strain NFX-FRZ (i) belongs to a novel species, termed Micractinium rhizosphaerae sp. nov.; (ii) can effectively bind to tomato plant tissues and promote its growth; (iii) can synthesize a wide range of plant growth-promoting compounds, including phytohormones such as indole-3-acetic acid, salicylic acid, jasmonic acid and abscisic acid; and (iv) contains multiple genes involved in phytohormone biosynthesis and signaling. This study provides new insights regarding the relevance of eukaryotic microalgae as plant growth-promoting agents and helps to build a foundation for future studies regarding the origin and evolution of phytohormone biosynthesis and signaling, as well as other plant colonization and plant growth-promoting mechanisms in soil/plant-associated Micractinium.publishersversionpublishe
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