1,957 research outputs found
Systematic performance measurement for university libraries in Vietnam
Version of RecordPublishe
Gwine to Heaben Some Day / music by Vernon Richner; words by Speed Langworthy
Description reads: Negro Spiritual with Male Quartet; Publisher: T. S. Denison and Company (Chicago)https://egrove.olemiss.edu/sharris_d/1101/thumbnail.jp
Rattle Em Bones / music by Fred Rose; words by Fred Rose
https://egrove.olemiss.edu/sharris_e/1000/thumbnail.jp
A Variable Metric Probabilistic k-Nearest-Neighbours Classifier
Copyright © 2004 Springer Verlag. The final publication is available at link.springer.com5th International Conference, Exeter, UK. August 25-27, 2004. ProceedingsBook title: Intelligent Data Engineering and Automated Learning – IDEAL 2004k-nearest neighbour (k-nn) model is a simple, popular classifier. Probabilistic k-nn is a more powerful variant in which the model is cast in a Bayesian framework using (reversible jump) Markov chain Monte Carlo methods to average out the uncertainy over the model parameters.The k-nn classifier depends crucially on the metric used to determine distances between data points. However, scalings between features, and indeed whether some subset of features is redundant, are seldom known a priori. Here we introduce a variable metric extension to the probabilistic k-nn classifier, which permits averaging over all rotations and scalings of the data. In addition, the method permits automatic rejection of irrelevant features. Examples are provided on synthetic data, illustrating how the method can deform feature space and select salient features, and also on real-world data
De Wes\u27 Wind Blows from de Wes\u27 / music by Larry E. Johnson; words by Larry E. Johnson
Cover: description reads exclusive novelty numbers for musical comedies, minstrels, vaudeville, revues and specialties; Publisher: T. S. Denison and Company (Chicago)https://egrove.olemiss.edu/sharris_d/1056/thumbnail.jp
Adapting the Finetech-Brindley Sacral Anterior Root Stimulator for Bioelectronic Medicine*
The Finetech-Brindley Sacral Anterior Root Stimulator (SARS) is a low cost and reliable system. The architecture has been used for various bioelectric treatments, including several thousand implanted systems for restoring bladder function following spinal cord injury (SCI). Extending the operational frequency range would expand the capability of the system; enabling, for example, the exploration of eliminating the rhizotomy through an electrical nerve block. The distributed architecture of the SARS system enables stimulation parameters to be adjusted without modifying the implant design or manufacturing. To explore the design degrees-of-freedom, a circuit simulation was created and validated using a modified SARS system that supported stimulation frequencies up to 600 Hz. The simulation was also used to explore high frequency (up to 30kHz) behaviour, and to determine the constraints on charge delivered at the higher rates. A key constraint found was the DC blocking capacitors, designed originally for low frequency operation, not fully discharging within a shortened stimulation period. Within these current implant constraints, we demonstrate the potential capability for higher frequency operation that is consistent with presynaptic stimulation block, and also define targeted circuit improvements for future extension of stimulation capability
Dietary carotenoid intake of individuals in the EPIC-Norfolk cohort is positively associated with percentage fat-free mass
Awareness, Co-operation, Tackling to Stop Sexual Bullying: An empowerment pack for young people and the people working with them (The ACT Pack).
Available in English, Bulgarian, Slovenian and Italia
Coronavirus Replicase-Reporter Fusions Provide Quantitative Analysis of Replication and Replication Complex Formation
The replication of coronaviruses occurs in association with multiple virus-induced membrane structures that evolve during the course of infection; however, the dynamics of this process remain poorly understood. Previous studies of coronavirus replication complex organization and protein interactions have utilized protein overexpression studies and immunofluorescence of fixed cells. Additionally, live-imaging studies of coronavirus replicase proteins have used fluorescent reporter molecules fused to replicase proteins, but expressed from nonnative locations, mostly late-transcribed subgenomic mRNAs, in the presence or absence of the native protein. Thus, the timing and targeting of native replicase proteins expressed in real time from native locations in the genome remain unknown. In this study, we tested whether reporter molecules could be expressed from the replicase polyprotein of murine hepatitis virus as fusions with nonstructural protein 2 or 3 and whether such reporters could define the targeting and activity of replicase proteins during infection. We demonstrate that the fusion of green fluorescent protein and firefly luciferase with either nonstructural protein 2 or 3 is tolerated and that these reporter-replicase fusions can be used to quantitate replication complex formation and virus replication. The results show that the replicase gene has flexibility to accommodate a foreign gene addition and can be used directly to study replicase complex formation and evolution during infection as well as to provide highly sensitive and specific markers for protein translation and genome replication
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