Osteotomia Pélvica de Salter modificada para tratamento de DDQ que pode melhorar a cobertura da cabeça femoral anterior e posterior

Objective: Three pelvic osteotomies (Salter, Dega, Pemberton) are widely used in walking patients under 7 years old for DDH treatment. We’ve proposed a modified Salter Pelvic Osteotomy (SPO), which has the advantages of the abovementioned osteotomies. Methods: Short- and mid-term results were assessed in 19 patients after modified SPO application. Patients were examined before and after the surgery, at 6 months postoperatively and at follow-up. Results: Acetabular Index (AI) before the surgery was 39.5 ± 7 °, after the surgery - 24.4 ± 5.5 °, at 6 months - 20.4 ± 5 ° (9-28), at follow-up - 14.5 ± 4 °; AI correction - 14.9 ± 5.5 °. Lateral Centre-Edge Angle at follow-up - 22.7 ± 4.7 °. Clinical results at follow-up were I / II McKay grade in 18 patients (94.7%); radiological results were  I / II Severin class in 18 patients (94.7%). Conclusion: Modified SPO allows to improve the FH coverage in any direction; results after modified SPO are excellent and good in the vast majority of patients. Level of Evidence IV, Case SeriesObjetivo: Três osteotomias pélvicas (Salter, Dega, Pemberton) são amplamente utilizadas em pacientes que andam com menos de 7 anos para o tratamento de DDQ. Propusemos uma Osteotomia Pélvica de Salter (SPO) modificada, que tem as vantagens das osteotomias acima mencionadas. Métodos: Os resultados de curto e médio prazo foram avaliados em 19 pacientes após a aplicação de SPO modificada. Os pacientes foram examinados antes e após a cirurgia, aos 6 meses de pós-operatório e no seguimento. Resultados: O índice acetabular (IA) antes da cirurgia era de 39,5 ± 7 °, após a cirurgia - 24,4 ± 5,5 °, aos 6 meses - 20,4 ± 5 ​​° (9-28), no seguimento - 14,5 ± 4 °; Correção AI - 14,9 ± 5,5 °. Lateral angulo centro-borda no acompanhamento - 22,7 ± 4,7 °. Os resultados clínicos no acompanhamento foram grau I / II de McKay em 18 pacientes (94,7%); os resultados radiológicos foram classe I / II de Severin em 18 pacientes (94,7%). Conclusão: O SPO modificado permite melhorar a cobertura de FH em qualquer direção; os resultados após SPO modificado são excelentes e bons na grande maioria dos pacientes. Nível de evidência IV, série de caso

MODIFIED SALTER PELVIC OSTEOTOMY FOR THE DDH TREATMENT

ABSTRACT Objectives: Three pelvic osteotomies (Salter, Dega, Pemberton) are widely used in walking patients under seven years old for DDH treatment. We’ve proposed a modified Salter Pelvic Osteotomy (SPO), which has the advantages of the abovementioned osteotomies. Methods: Short- and mid-term results were assessed in 19 patients after the modified SPO application. Patients were examined before and after the surgery, at 6 months postoperatively, and at follow-up. Results: Acetabular Index (AI) before the surgery was 39.5 ± 7 °; after the surgery - 24.4 ± 5.5 °, at 6 months - 20.4 ± 5 ° (9-28), at follow-up - 14.5 ± 4 °; AI correction - 14.9 ± 5.5 °. Lateral Centre-Edge Angle at follow-up - 22.7 ± 4.7 °. Clinical results at follow-up were I / II McKay grade in 18 patients (94.7%); radiological results were I / II Severin class in 18 patients (94.7%). Conclusion: Modified SPO improves the FH coverage in any direction; results after modified SPO are excellent and good in most patients. Level of Evidence IV; Case Series

Determination of fracture toughness for small-sized specimens with ultrafine grain structure

The results of changing the fracture toughness of materials are given for the VT6 titanium alloy. Its coarse grain structure was reduced down to ultrafine structure by forging. The specific energy of fracture [gamma] for the small-sized chevron-notched specimens was found thanks to the new technique. It is shown that severe plastic deformation reduces [gamma] at room temperature. The structure of the surface fracture of the VT6 alloy’s ultrafine grain structure can be conceived as local zones of strong deformed material with a high concentration of pores. Such kind of structure cannot be formed only by means of crystallographic shears along close-packed planes. That fact proves the cardinal role of rotational modes of deformation in the origination and formation of a crack at various scale levels

The First Selenoanhydride in the Series of Chlorophyll a Derivatives, Its Stability and Photoinduced Cytotoxicity

In this work, we obtained the first selenium-containing chlorin with a chalcogen atom in exlocycle E. It was shown that the spectral properties were preserved in the target compound and the stability increased at two different pH values, in comparison with the starting purpurin-18. The derivatives have sufficiently high fluorescence and singlet oxygen quantum yields. The photoinduced cytotoxicity of sulfur- and selenium-anhydrides of chlorin p6 studied for the first time in vitro on the S37 cell line was found to be two times higher that of purpurin-18 and purpurinimide studied previously. Moreover, the dark cytotoxicity increased four-fold in comparison with the latter compounds. Apparently, the increase in the dark cytotoxicity is due to the interaction of the pigments studied with sulfur- and selenium-containing endogenous intracellular compounds. Intracellular distributions of thioanhydride and selenoanhydride chlorin p6 in S37 cells were shown in cytoplasm by diffusion distribution. The intracellular concentration of the sulfur derivative turned out to be higher and, as a consequence, its photoinduced cytotoxicity was higher as well

DUNE Offline Computing Conceptual Design Report

This document describes Offline Software and Computing for the Deep Underground Neutrino Experiment (DUNE) experiment, in particular, the conceptual design of the offline computing needed to accomplish its physics goals. Our emphasis in this document is the development of the computing infrastructure needed to acquire, catalog, reconstruct, simulate and analyze the data from the DUNE experiment and its prototypes. In this effort, we concentrate on developing the tools and systems thatfacilitate the development and deployment of advanced algorithms. Rather than prescribing particular algorithms, our goal is to provide resources that are flexible and accessible enough to support creative software solutions as HEP computing evolves and to provide computing that achieves the physics goals of the DUNE experiment

Reconstruction of interactions in the ProtoDUNE-SP detector with Pandora

International audienceThe Pandora Software Development Kit and algorithm libraries provide pattern-recognition logic essential to the reconstruction of particle interactions in liquid argon time projection chamber detectors. Pandora is the primary event reconstruction software used at ProtoDUNE-SP, a prototype for the Deep Underground Neutrino Experiment far detector. ProtoDUNE-SP, located at CERN, is exposed to a charged-particle test beam. This paper gives an overview of the Pandora reconstruction algorithms and how they have been tailored for use at ProtoDUNE-SP. In complex events with numerous cosmic-ray and beam background particles, the simulated reconstruction and identification efficiency for triggered test-beam particles is above 80% for the majority of particle type and beam momentum combinations. Specifically, simulated 1 GeV/$c$ charged pions and protons are correctly reconstructed and identified with efficiencies of 86.1$\pm0.6$% and 84.1$\pm0.6$%, respectively. The efficiencies measured for test-beam data are shown to be within 5% of those predicted by the simulation