228 research outputs found

    05031 Abstracts Collection -- Algorithms for Optimization with Incomplete Information

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    From 16.01.05 to 21.01.05, the Dagstuhl Seminar 05031 ``Algorithms for Optimization with Incomplete Information\u27\u27 was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the seminar topics and goals in general. Links to extended abstracts or full papers are provided, if available

    The contribution of tsunami evacuation analysis to evacuation planning in Chile: Applying a multi-perspective research design

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    Research on evacuation behavior in natural disasters provides a valuable contribution in the development of effective short- and long-term strategies in disaster risk management (DRM). Many studies address evacuation simulation utilizing mathematical modeling approaches or GIS-based simulation. In this contribution, we perform a detailed analysis of an entire evacuation process from the decision to evacuate right up to the arrival at a safe zone. We apply a progressive research design in the community of Talcahuano, Chile by means of linking a social science approach, deploying standardized questionnaires for the tsunami affected population, and a GIS-based simulation. The questionnaire analyzes evacuation behavior in both an event-based historical scenario and a hypothetical future scenario. Results reveal three critical issues: evacuation time, distance to the evacuation zone, and method of transportation. In particular, the excessive use of cars has resulted in congestion of street sections in past evacuations, and will most probably also pose a problem in a future evacuation event. As evacuation by foot is generally recommended by DRM, the results are extended by a GIS-based modeling simulating evacuation by foot. Combining the findings of both approaches allows for added value, providing more comprehensive insights into evacuation planning. Future research may take advantage of this multi-perspective research design, and integrate social science findings in a more detailed manner. Making use of invaluable local knowledge and past experience of the affected population in evacuation planning is likely to help decrease the magnitude of a disaster, and, ultimately, save lives

    Stability of surfaces in the chalcopyrite system

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    It has been observed previously that the stable surfaces in chalcopyrites are the polar 112 surfaces. We present an electron microscopy study of epitaxial films of different compositions. It is shown that for both CuGaSe2 and CuInSe2 the 001 surfaces form 112 facets. With increasing Cu excess the faceting is suppressed, indicating a lower surface energy of the 001 surface than the energy of the 112 surface in the Cu rich regime, but the 001 surface is higher in energy than the 112 surface in the Cu poor regime. As both surfaces are polar the stabilization is attributed to defect formatio

    Evaluation of the London Measure of Unplanned Pregnancy in a United States population of women

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    Copyright @ 2012 Morof et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Objective: To evaluate the reliability and validity of the London Measure of Unplanned Pregnancy (a U.K.-developed measure of pregnancy intention), in English and Spanish translation, in a U.S. population of women. Methods: A psychometric evaluation study of the London Measure of Unplanned Pregnancy (LMUP), a six-item, self-completion paper measure was conducted with 346 women aged 15–45 who presented to San Francisco General Hospital for termination of pregnancy or antenatal care. Analyses of the two language versions were carried out separately. Reliability (internal consistency) was assessed using Cronbach’s alpha and item-total correlations. Test-retest reliability (stability) was assessed using weighted Kappa. Construct validity was assessed using principal components analysis and hypothesis testing. Results: Psychometric testing demonstrated that the LMUP was reliable and valid in both U.S. English (alpha = 0.78, all item-total correlations .0.20, weighted Kappa = 0.72, unidimensionality confirmed, hypotheses met) and Spanish translation (alpha = 0.84, all item-total correlations .0.20, weighted Kappa = 0.77, unidimensionality confirmed, hypotheses met). Conclusion: The LMUP was reliable and valid in U.S. English and Spanish translation and therefore may now be used with U.S. women.The study was funded by an anonymous donation

    Regularizing Portfolio Optimization

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    The optimization of large portfolios displays an inherent instability to estimation error. This poses a fundamental problem, because solutions that are not stable under sample fluctuations may look optimal for a given sample, but are, in effect, very far from optimal with respect to the average risk. In this paper, we approach the problem from the point of view of statistical learning theory. The occurrence of the instability is intimately related to over-fitting which can be avoided using known regularization methods. We show how regularized portfolio optimization with the expected shortfall as a risk measure is related to support vector regression. The budget constraint dictates a modification. We present the resulting optimization problem and discuss the solution. The L2 norm of the weight vector is used as a regularizer, which corresponds to a diversification "pressure". This means that diversification, besides counteracting downward fluctuations in some assets by upward fluctuations in others, is also crucial because it improves the stability of the solution. The approach we provide here allows for the simultaneous treatment of optimization and diversification in one framework that enables the investor to trade-off between the two, depending on the size of the available data set

    Antecedent Avian Immunity Limits Tangential Transmission of West Nile Virus to Humans

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    Background: West Nile virus (WNV) is a mosquito-borne flavivirus maintained and amplified among birds and tangentially transmitted to humans and horses which may develop terminal neuroinvasive disease. Outbreaks typically have a three-year pattern of silent introduction, rapid amplification and subsidence, followed by intermittent recrudescence. Our hypothesis that amplification to outbreak levels is contingent upon antecedent seroprevalence within maintenance host populations was tested by tracking WNV transmission in Los Angeles, California from 2003 through 2011. Methods: Prevalence of antibodies against WNV was monitored weekly in House Finches and House Sparrows. Tangential or spillover transmission was measured by seroconversions in sentinel chickens and by the number of West Nile neuroinvasive disease (WNND) cases reported to the Los Angeles County Department of Public Health. Results: Elevated seroprevalence in these avian populations was associated with the subsidence of outbreaks and in the antecedent dampening of amplification during succeeding years. Dilution of seroprevalence by recruitment resulted in the progressive loss of herd immunity following the 2004 outbreak, leading to recrudescence during 2008 and 2011. WNV appeared to be a significant cause of death in these avian species, because the survivorship of antibody positive birds significantly exceeded that of antibody negative birds. Cross-correlation analysis showed that seroprevalence was negatively correlated prior to the onset of human cases and then positively correlated, peaking at 4–6 weeks after the onse

    Non-response in a survey of physicians on end-of-life care for the elderly

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    <p>Abstract</p> <p>Background</p> <p>Physicians are quite often surveyed with the aim to investigate their opinions regarding provision and improvement of health care. However, in many cases response rates tend to be rather low. The aim of the study is to reflect methodological aspects regarding survey conduction and to analyse factors that cause physicians to take part in a study on delivering end-of-life care for the elderly.</p> <p>Methods</p> <p>N = 4,727 physicians in Lower Saxony, Germany, received a standardised questionnaire on their attitudes about end-of-life care for the elderly. Non-responders were asked to state the reasons for non-participation. Comparison of the sociodemographic characteristics between responders and non-responders, and evaluation of the reasons for non-participation were made.</p> <p>Results</p> <p>The response rate to the questionnaire on end-of-life care for the elderly was 40% (n = 1,892). Of the non-responders to the questionnaire, 12.8% (n = 364) stated the reasons for non-participation. Overall, the response rate to the questionnaire varied with specialty and location of the practice: radiotherapists answered significantly more frequently than other categories of physician (e.g. general practitioners) and physicians in rural areas significantly more frequently than their colleagues in urban areas. The reasons most frequently given for non-participation were "Not concerned with the subject" and "No time".</p> <p>Conclusions</p> <p>The varying rates of response indicate that the survey was not sufficiently relevant to all groups of physicians, or that the awareness of the topic may be partly underdeveloped.</p
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