4 research outputs found
Additional file 1: of Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition
The effect of SFN in cell viability of TGF-β1-stimulated cells for 24, 48, and 72 h. In A549 cells, TGF-β1 did not induce significant proliferation (A). TGF-β1-induced proliferation of MRC-5 cells showed inhibition by treatment of SFN for 1 h (B). (PDF 315 kb
Additional file 2: of Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition
Time response in the phosphorylation of SMAD2/3 by TGF-β1 and SFN treatment. In Western blotting of both A549 cells (A) and MRC-5 cells (B) showed phosphorylation of SMAD2/3 in early time within 1 h by TGF-β1. (PDF 113 kb
Additional file 1: Table S1. of Predicting survival of patients with idiopathic pulmonary fibrosis using GAP score: a nationwide cohort study
Comorbidities of idiopathic pulmonary fibrosis patients according to GAP score. Table S2. Initial presenting symptoms of study population. Table S3. Survival analysis with Cox proportional hazard model including age, sex, FVC (%), DLCO (%), and smoking. (DOCX 23 kb
Additional file 1: Table S1. of Factors affecting treatment outcome in patients with idiopathic nonspecific interstitial pneumonia: a nationwide cohort study
Treatment modality in treatment group (n = 86). Table S2. Comorbidities of study population. Table S3. Comparison between initial and 1-year follow-up lung function according to treatment. Table S4. Analysis of risk factors that associated with treatment failure (by logistic regression). (DOCX 26 kb