PET and P300 Relationships in Early Alzheimer\u27s Disease

The P300 (P3) wave of the auditory brain event-related potential was investigated in patients with probable Alzheimer\u27s disease to determine whether P300 latency discriminated these patients from controls and whether prolonged P300 latency correlated with rates of brain glucose metabolism as measured by Positron Emission Tomography. P300 latency was prolonged by more than 1.5 standard deviations from age expectancy in 14 of 18 patients, but none of 17 controls. In these subjects P300 latency was shown to be inversely correlated with relative metabolic rates of parietal and, to a lesser extent, temporal and frontal association areas, but not with subcortical areas

PET and P300 relationships in early Alzheimer's disease

The P300 (P3) wave of the auditory brain event-related potential was investigated in patients with probable Alzheimer's disease to determine whether P300 latency discriminated these patients from controls and whether prolonged P300 latency correlated with rates of brain glucose metabolism as measured by Positron Emission Tomography. P300 latency was prolonged by more than 1.5 standard deviations from age expectancy in 14 of 18 patients, but none of 17 controls. In these subjects P300 latency was shown to be inversely correlated with relative metabolic rates of parietal and, to a lesser extent, temporal and frontal association areas, but not with subcortical areas.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28511/1/0000308.pd

PSYC 318-01, Physiological Psychology, Fall 1998

This syllabus was submitted to the Rhodes College Office of Academic Affairs by the course instructorThe goal of this course is to develop the student's ability to think critically about the relationship between the brain and human behavior. Our understanding of this relationship varies greatly across the phenomena typically addressed by psychologists (perception, emotion, thought, motivation, psychopathology, etc, etc), and we will cover representative work (the methods, findings and theories) in each of these areas as noted in the course outline. At the outset (Part I above) the student must develop a basic understanding of the physiological, pharmacological and anatomical principles which apply to all of the psychological phenomena we will study. We will then examine perceptual and motor systems (Part II) to gain an understanding of how information is coded and transformed in the nervous system. In Part III we will address a variety of motivated behaviors (eating, sleeping, reproducing etc) to gain insight into the interplay of various neural systems in behavioral activation and homeostatic regulation. Finally, in Part IV we will look at a variety of complex psychological phenomena such as language and psychopathology attempting to pull together the principles developed in Parts I, II and III

Summer Service Fellows Announcement

Rhodes CARES is pleased to announce the 2007 Summer Service Fellowships and their projects

PSYC 226-01, Learning and Memory, Fall 1998

This syllabus was submitted to the Rhodes College Office of Academic Affairs by the course instructo

CHEM 485-01, Senior Seminar, Fall 2003

This syllabus was submitted to the Office of Academic Affairs by the course instructor.Senior Seminars are designed to further critical thinking skills through the exploration and discussion of primary research literature, and to provide an opportunity to improve oral and written communication skills

Automated proximity sensing in small vertebrates: design of miniaturized sensor nodes and first field tests in bats

Social evolution has led to a stunning diversity of complex social behavior, in particular in vertebrate taxa. Thorough documentation of social interactions is crucial to study the causes and consequences of sociality in gregarious animals. Wireless digital transceivers represent a promising tool to revolutionize data collection for the study of social interactions in terms of the degree of automation, data quantity, and quality. Unfortunately, devices for automated proximity sensing via direct communication among animal-borne sensors are usually heavy and do not allow for the investigation of small animal species, which represent the majority of avian and mammalian taxa. We present a lightweight animal-borne sensor node that is built from commercially available components and uses a sophisticated scheme for energy-efficient communication, with high sampling rates at relatively low power consumption. We demonstrate the basic functionality of the sensor node under laboratory conditions and its applicability for the study of social interactions among free-ranging animals. The first field tests were performed on two species of bats in temperate and tropical ecosystems. At <2 g, this sensor node is light enough to observe a broad spectrum of taxa including small vertebrates. Given our specifications, the system was especially sensitive to changes in distance within the short range (up to a distance of 4 m between tags). High spatial resolution at short distances enables the evaluation of interactions among individuals at a fine scale and the investigation of close contacts. This technology opens new avenues of research, allowing detailed investigation of events associated with social contact, such as mating behavior, pathogen transmission, social learning, and resource sharing. Social behavior that is not easily observed becomes observable, for example, in animals living in burrows or in nocturnal animals. A switch from traditional methods to the application of digital transceiver chips in proximity sensing offers numerous advantages in addition to an enormous increase in data quality and quantity. For future applications, the platform allows for the integration of additional sensors that may collect physiological or environmental data. Such information complements social network studies and may allow for a deeper understanding of animal ecology and social behavior.This work was funded by the German Science Foundation (DFG grant FOR 1508, Research Unit BATS). The publication of this article was funded by the Open Access fund of the Leibniz Association