Editorial

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Active flutter control for flexible vehicles, volume 1

An active flutter control methodology based on linear quadratic gaussian theory and its application to the control of a super critical wing is presented. Results of control surface and sensor position optimization are discussed. Both frequency response matching and residualization used to obtain practical flutter controllers are examined. The development of algorithms and computer programs for flutter modeling and active control design procedures is reported

Putting the ‘me’ in mechanical: lessons from the mechanical men of health 1928–1948

During the interwar years, health exhibitions and pavilions were commonplace in Europe and the USA. Within these exhibitions were a small number of life-sized or oversized mechanical men used to represent physiological processes. Although they received significant press attention at the time, little academic analysis exists to date. These mechanical men, I argue, all provide important insights regarding the way design could be used to heighten the appeal of physiology and crucially, in the formation of a new term—the Accessible Body. First, this study re-introduces three mechanical men of health to an academic audience, identifying provenance and unearthing key details of their performance and visual appearance. I argue that there is much to be gained by their analysis in comparison to the more notorious body representations that they orbited. Through detailed analysis of their forms, the three mechanical men are shown to challenge the dominant notions of the Ideal Body and Fordist Body embodied in the Dresden Transparent Man (1930) and ‘Der Mensch als Industriepalast’ (1926), respectively. The study examines and classifies these mechanical men as a new type of body— the Accessible Body. This term refers to representations that embody a sense of consciousness, the re-appropriation of popular culture and engagement with humour and visual appeal. The study concludes with discussion about the Accessible Body in contemporary health education. What tropes and approaches may remain significant today? By leaning on contemporary thinking about linguistic rather than visual metaphors in health, this study concludes with provocations for the alignment of other appropriate metaphors within a mechanical man and Accessible Body framework. Ultimately, I call for a reshifting of man/machine visual metaphors as a means of re-engaging the audience today

A bioinformatics approach to the development of immunoassays for specified risk material in canned meat products

A bioinformatics approach to developing antibodies to specific proteins has been evaluated for the production of antibodies to heat-processed specified risk tissues from ruminants (brain and eye tissue). The approach involved the identification of proteins specific to ruminant tissues by interrogation of the annotation fields within the Swissprot database. These protein sequences were then interrogated for peptide sequences that were unique to the protein. Peptides were selected that met these criteria as close as possible and that were also theoretically resistant to either pepsin or trypsin. The selected peptides were synthesised and used as immunogens to raise monoclonal antibodies. Antibodies specific for the synthetic peptides were raised to half of the selected peptides. These antibodies have each been incorporated into a competitive enzyme-linked immunosorbent assay (ELISA) and shown to be able to detect the heat-processed parent protein after digestion with either pepsin or trypsin. One antibody, specific for alpha crystallin peptide (from bovine eye tissue), was able to detect the peptide in canned meat products spiked with 10% eye tissue. These results, although preliminary in nature, show that bioinformatics in conjunction with enzyme digestion can be used to develop ELISA for proteins in high-temperature processed foods and demonstrate that the approach is worth further stud

Effectiveness and Efficiency of Persuasive Space Graphics (PSG) in Motivating UK Primary School Children’s Hand Hygiene

Good hand hygiene is necessary to control and prevent infections, but many children do not adequately wash their hands. While there are classroom communications targeted at children, the toilet space, the location of many hand hygiene activities, is neglected. This paper describes an initial evaluation of “123” persuasive space graphics (images and messages integrated within an architectural environment that encourage specific actions). The effectiveness (whether hand hygiene improves) and efficiency (the ease with which a setting can adopt and implement an intervention) is evaluated in three UK schools and one museum. Five evaluations (participant demographic, handwashing frequency, handwashing quality, design persuasiveness, stakeholder views) were conducted. In the school settings, persuasive space graphics increased the quality and frequency of handwashing. In the museum setting, frequency of handwashing slightly increased. In all settings children found the graphics persuasive, and stakeholders also believed them to be effective. Stakeholders considered persuasive space graphics a low-cost and time-efficient way to communicate. It can be concluded that persuasive space graphics are effective in increasing hand hygiene, particularly in school settings where children have a longer exposure to the graphics. Persuasive space graphics are also an efficient low-cost means of communicating hand hygiene

THE ROLES OF MONEY IN AN ECONOMY AND THE OPTIMUM QUANTITY OF MONEY

What is the optimum quantity of money in a society? This paper answers this question both from the perspective of a utility maximizing model with real balances in the utility function, and employing an inventory theoretic model which focuses attention on the costs of transacting in different markets and on the storage costs of holding money. We find that socially optimal transactions patterns and inventory holdings can be induced by paying interest on money and bonds equal to the net rate of return on capital. This conclusion is however only valid if it is costless for the society to institute and operate such an interest payment mechanism. In a world where it is costly to institute and operate an interest payment mechanism, a social optimum requires that the rate of return on money and bonds must equal the net rate of return on capital minus the social cost of inducing individuals to hold optimal quantities of financial assets. It is therefore necessary to take account of both the potential gains in welfare from instituting interest payments on money and the real potential costs of such a policy. Reference: Economica, November, 1973 pp. 416-431

Constructing representations of germs in the twentieth century

The development of germ theories of disease was reliant on the exchange of representations and descriptions of microorganisms. Visual properties were critical in establishing a shared understanding of agents of disease and their causal role. However, historians have yet to explore in detail the representation of microorganisms aimed at audiences beyond specialists. The public visual culture of germs offers a new window through which to understand health campaigns, their motivations, and intended audiences. We argue that still and moving images of germs made visible social anxieties surrounding health, race, class, and national security in ways not yet recognised

The South African paediatric tumour registry - 25 years of activity

The South African Children’s Tumour Registry was established 25 years ago as it was essential to collect data on malignant disease in the paediatric population that can be used for statistical research in an efficient and sustainable way. The Registry is a useful and significant repository of specific paediatric data, along with the recently revitalised National Cancer Registry, to serve the needs of the cancer research community

Using FaceReader to explore the potential for harnessing emotional reactions to motivate hand hygiene

Background: Handwashing is a key strategy for reducing the spread of infection but hand hygiene practises are often poor. Pre-testing messages prior to a campaign is expensive and time consuming. Objective: This study investigates (1) emotional reactions to handwashing messages based on four different theoretical constructs (Knowledge of Risk, Comfort, Disgust and Social Norms), (2) how images may influence emotional reactions and (3) the influence of emotion, images and theoretical construct on handwashing motivation. Methods A novel methodology was employed whereby FaceReader, software that automatically analyses emotions, was used to identify reactions to handwashing messages. Thirty-one participants from The University of Sheffield were recruited for this laboratory study. Results: Most participants did not react strongly to any message and emotional reactions were similar for messages from different theoretical constructs. Adding images to text messages intensified some emotional reactions, particularly Happy and Disgusted for the two messages from the Disgust theoretical perspective. Moreover, participants thought that messages that used images were 1.8 times more likely to encourage handwashing. Knowledge of Risk messages (most encouraging) were 2.9 times more likely to be selected as encouraging handwashing than Comfort messages (least encouraging). An increase in the Disgusted emotion was also associated with an increase in encouragement. Discussion: This study suggests that handwashing messages should be designed to exploit emotional reactions but more research is needed to understand how to design messages for these reactions. Whether disgust is as important post Covid-19 requires future investigation. FaceReader can be usefully and inexpensively employed to pre-test handwashing messages

Evaluating children's handwashing in schools: an integrative review of indicative measures and measurement tools.

Children are a key target of handwashing interventions as washing hands reduces the spread of disease and reliance on antibiotics. While there is guidance for evaluating handwashing with adults in other settings, this is lacking for children in schools. An integrative review of 65 studies where handwashing was measured in schools was conducted to establish which indicative measures (what is measured to evaluate the processes and/or impacts of, handwashing) and measurement tools (data collection instruments) have been applied to evaluate handwashing in schools, and under what circumstances. Further analysis highlighted different challenges when seeking to apply such measures and tools in schools, as opposed to other settings. It was concluded that indicative measures, and measurement tools need to be appropriate to the organizational setting, the study participants, and research objectives. A summative analysis of relevant considerations is presented