38,080 research outputs found
ATTac-2000: An Adaptive Autonomous Bidding Agent
The First Trading Agent Competition (TAC) was held from June 22nd to July
8th, 2000. TAC was designed to create a benchmark problem in the complex domain
of e-marketplaces and to motivate researchers to apply unique approaches to a
common task. This article describes ATTac-2000, the first-place finisher in
TAC. ATTac-2000 uses a principled bidding strategy that includes several
elements of adaptivity. In addition to the success at the competition, isolated
empirical results are presented indicating the robustness and effectiveness of
ATTac-2000's adaptive strategy
Magnetic collimation of protostellar winds into bipolar outflows
Researchers describe self-consistent 2-D magnetohydrodynamic (MHD) simulations of the collimation of an isotropic protostellar wind into bipolar outflows by magnetic stresses in the ambient medium. A variety of ambient field strengths, wind luminosities, and density profiles were studied. Collimation occurs when the energy of the magnetic field swept up by the expanding bubble approaches the bubble thermal energy. Measured axial and radial expansion rates are in good agreement with the analytical predictions of Konigl (1982)
An expert system that performs a satellite station keepimg maneuver
The development and characteristics of a prototype expert system, Expert System for Satellite Orbit Control (ESSOC), capable of providing real-time spacecraft system analysis and command generation for a geostationary satellite are described. The ESSOC recommends appropriate commands that reflect both the changing spacecraft condition and previous procedural action. An internal knowledge base stores satellite status information and is updated with processed spacecraft telemetry. Procedural structure data are encoded in production rules. Structural methods of knowledge acquisition and the design and performance-enhancing techniques that enable ESSOC to operate in real time are also considered
Constraining the Sub-AU-Scale Distribution of Hydrogen and Carbon Monoxide Gas around Young Stars with the Keck Interferometer
We present Keck Interferometer observations of T Tauri and Herbig Ae/Be stars
with a spatial resolution of a few milliarcseconds and a spectral resolution of
~2000. Our observations span the K-band, and include the Br gamma transition of
Hydrogen and the v=2-0 and v=3-1 transitions of carbon monoxide. For several
targets we also present data from Keck/NIRSPEC that provide higher spectral
resolution, but a seeing-limited spatial resolution, of the same spectral
features. We analyze the Br gamma emission in the context of both disk and
infall/outflow models, and conclude that the Br gamma emission traces gas at
very small stellocentric radii, consistent with the magnetospheric scale.
However some Br gamma-emitting gas also seems to be located at radii of >0.1
AU, perhaps tracing the inner regions of magnetically launched outflows. CO
emission is detected from several objects, and we generate disk models that
reproduce both the KI and NIRSPEC data well. We infer the CO spatial
distribution to be coincident with the distribution of continuum emission in
most cases. Furthermore the Br gamma emission in these objects is roughly
coincident with both the CO and continuum emission. We present potential
explanations for the spatial coincidence of continuum, Br gamma, and CO
overtone emission, and explore the implications for the low occurrence rate of
CO overtone emission in young stars. Finally, we provide additional discussion
of V1685 Cyg, which is unusual among our sample in showing large differences in
emitting region size and spatial position as a function of wavelength.Comment: Accepted for publication in MNRA
Dependence receptor involvement in subtilisin-induced long-term depression and in long-term potentiation
The serine protease subtilisin induces a form of long-term depression (LTD) which is accompanied by a reduced expression of the axo-dendritic guidance molecule Unco-ordinated-5C (Unc-5C). One objective of the present work was to determine whether a loss of Unc-5C function contributed to subtilisin-induced LTD by using Unc-5C antibodies in combination with the pore-forming agents Triton X-100 (0.005%) or streptolysin O in rat hippocampal slices. In addition we have assessed the effect of subtilisin on the related dependence receptor Deleted in Colorectal Cancer (DCC) and used antibodies to this protein for functional studies. Field excitatory postsynaptic potentials (fEPSPs) were analysed in rat hippocampal slices and protein extracts were used for Western blotting. Subtilisin produced a greater loss of DCC than of Unc-5C, but the antibodies had no effect on resting excitability or fEPSPs and did not modify subtilisin-induced LTD. However, antibodies to DCC but not Unc-5C did reduce the amplitude of theta-burst long-term potentiation (LTP). In addition, two inhibitors of endocytosis – dynasore and tat-gluR2(3Y) – were tested and, although the former compound had no effect on neurophysiological responses, tat-gluR2(3Y) did reduce the amplitude of subtilisin-induced LTD without affecting the expression of DCC or Unc-5C but with some loss of PostSynaptic Density Protein-95. The results support the view that the dependence receptor DCC may be involved in LTP and suggest that the endocytotic removal of a membrane protein or proteins may contribute to subtilisin-induced LTD, although it appears that neither Unc-5C nor DCC are involved in this process. (220)
Quasi-Chemical and Structural Analysis of Polarizable Anion Hydration
Quasi-chemical theory is utilized to analyze the roles of solute polarization
and size in determining the structure and thermodynamics of bulk anion
hydration for the Hofmeister series Cl, Br, and I. Excellent
agreement with experiment is obtained for whole salt hydration free energies
using the polarizable AMOEBA force field. The quasi-chemical approach exactly
partitions the solvation free energy into inner-shell, outer-shell packing, and
outer-shell long-ranged contributions by means of a hard-sphere condition.
Small conditioning radii, even well inside the first maximum of the
ion-water(oxygen) radial distribution function, result in Gaussian behavior for
the long-ranged contribution that dominates the ion hydration free energy. The
spatial partitioning allows for a mean-field treatment of the long-ranged
contribution, leading to a natural division into first-order electrostatic,
induction, and van der Waals terms. The induction piece exhibits the strongest
ion polarizability dependence, while the larger-magnitude first-order
electrostatic piece yields an opposing but weaker polarizability dependence. In
addition, a structural analysis is performed to examine the solvation
anisotropy around the anions. As opposed to the hydration free energies, the
solvation anisotropy depends more on ion polarizability than on ion size:
increased polarizability leads to increased anisotropy. The water dipole
moments near the ion are similar in magnitude to bulk water, while the ion
dipole moments are found to be significantly larger than those observed in
quantum mechanical studies. Possible impacts of the observed over-polarization
of the ions on simulated anion surface segregation are discussed.Comment: slight revision, in press at J. Chem. Phy
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