The proper motion of the Arches cluster with Keck Laser-Guide Star Adaptive Optics

We present the first measurement of the proper motion of the young, compact Arches cluster near the Galactic center from near-infrared adaptive optics (AO) data taken with the recently commissioned laser-guide star (LGS) at the Keck 10-m telescope. The excellent astrometric accuracy achieved with LGS-AO provides the basis for a detailed comparison with VLT/NAOS-CONICA data taken 4.3 years earlier. Over the 4.3 year baseline, a spatial displacement of the Arches cluster with respect to the field population is measured to be 24.0 +/- 2.2 mas, corresponding to a proper motion of 5.6 +/- 0.5 mas/yr or 212 +/- 29 km/s at a distance of 8 kpc. In combination with the known line-of-sight velocity of the cluster, we derive a 3D space motion of 232 +/- 30 km/s of the Arches relative to the field. The large proper motion of the Arches cannot be explained with any of the closed orbital families observed in gas clouds in the bar potential of the inner Galaxy, but would be consistent with the Arches being on a transitional trajectory from x1 to x2 orbits. We investigate a cloud-cloud collision as the possible origin for the Arches cluster. The integration of the cluster orbit in the potential of the inner Galaxy suggests that the cluster passes within 10 pc of the supermassive black hole only if its true GC distance is very close to its projected distance. A contribution of young stars from the Arches cluster to the young stellar population in the inner few parsecs of the GC thus appears increasingly unlikely. The measurement of the 3D velocity and orbital analysis provides the first observational evidence that Arches-like clusters do not spiral into the GC. This confirms that no progenitor clusters to the nuclear cluster are observed at the present epoch.Comment: 22 pdflatex pages including 12 figures, reviewed version accepted by Ap

Multiple episodes of star formation in the CN15/16/17 molecular complex

We have started a campaign to identify massive star clusters inside bright molecular bubbles towards the Galactic Center. The CN15/16/17 molecular complex is the first example of our study. The region is characterized by the presence of two young clusters, DB10 and DB11, visible in the NIR, an ultra-compact HII region identified in the radio, several young stellar objects visible in the MIR, a bright diffuse nebulosity at 8\mu m coming from PAHs and sub-mm continuum emission revealing the presence of cold dust. Given its position on the sky (l=0.58, b=-0.85) and its kinematic distance of ~7.5 kpc, the region was thought to be a very massive site of star formation in proximity of the CMZ. The cluster DB11 was estimated to be as massive as 10^4 M_sun. However the region's properties were known only through photometry and its kinematic distance was very uncertain given its location at the tangential point. We aimed at better characterizing the region and assess whether it could be a site of massive star formation located close to the Galactic Center. We have obtained NTT/SofI JHKs photometry and long slit K band spectroscopy of the brightest members. We have additionally collected data in the radio, sub-mm and mid infrared, resulting in a quite different picture of the region. We have confirmed the presence of massive early B type stars and have derived a spectro-photometric distance of ~1.2 kpc, much smaller than the kinematic distance. Adopting this distance we obtain clusters masses of M(DB10) ~ 170 M_sun and M(DB11) ~ 275 M_sun. This is consistent with the absence of any O star, confirmed by the excitation/ionization status of the nebula. No HeI diffuse emission is detected in our spectroscopic observations at 2.113\mu m, which would be expected if the region was hosting more massive stars. Radio continuum measurements are also consistent with the region hosting at most early B stars.Comment: Accepted for publication in Astronomy and Astrophysics. Fig. 1 and 3 presented in reduced resolutio

Faecalibacterium prausnitzii Strain HTF-F and Its Extracellular Polymeric Matrix Attenuate Clinical Parameters in DSS-Induced Colitis

Date of Acceptance: 26/02/2015 Funding: The authors received no specific funding for this work.Peer reviewedPublisher PD

Deep near-infrared imaging of W3 Main: constraints on stellar cluster formation

Embedded clusters like W3 Main are complex and dynamically evolving systems that represent an important phase of the star formation process. We aim at the characterization of the entire stellar content of W3 Main in a statistical sense to identify possible differences in evolutionary phase of the stellar populations and find clues about the formation mechanism of this massive embedded cluster. Methods. Deep JHKs imaging is used to derive the disk fraction, Ks-band luminosity functions and mass functions for several subregions in W3 Main. A two dimensional completeness analysis using artificial star experiments is applied as a crucial ingredient to assess realistic completeness limits for our photometry. We find an overall disk fraction of 7.7 $\pm$ 2.3%, radially varying from 9.4 $\pm$ 3.0 % in the central 1 pc to 5.6 $\pm$ 2.2 % in the outer parts of W3 Main. The mass functions derived for three subregions are consistent with a Kroupa and Chabrier mass function. The mass function of IRSN3 is complete down to 0.14 Msun and shows a break at M $\sim$ 0.5 Msun. We interpret the higher disk fraction in the center as evidence for a younger age of the cluster center. We find that the evolutionary sequence observed in the low-mass stellar population is consistent with the observed age spread among the massive stars. An analysis of the mass function variations does not show evidence for mass segregation. W3 Main is currently still actively forming stars, showing that the ionizing feedback of OB stars is confined to small areas ($\sim$ 0.5 pc). The FUV feedback might be influencing large regions of the cluster as suggested by the low overall disk fraction.Comment: 15 pages, 13 figures, accepted by A&

Age spread in Galactic star forming region W3 Main

We present near-infrared JHKs imaging as well as K-band multi-object spectroscopy of the massive stellar content of W3 Main using LUCI at the LBT. We confirm 13 OB stars by their absorption line spectra in W3 Main and spectral types between O5V and B4V have been found. Three massive Young Stellar Objects are identified by their emission line spectra and near-infrared excess. From our spectrophotometric analysis of the massive stars and the nature of their surrounding HII regions we derive the evolutionary sequence of W3 Main and we find an age spread of 2-3 Myr.Comment: 4 pages, 2 figures, To appear in conference proceedings of "370 years of Astronomy in Utrecht

HST/NICMOS Paschen-alpha Survey of the Galactic Center: Overview

We have recently carried out the first wide-field hydrogen Paschen-alpha line imaging survey of the Galactic Center (GC), using the NICMOS instrument aboard the Hubble Space Telescope. The survey maps out a region of 2253 pc^2 around the central supermassive black hole (Sgr A*) in the 1.87 and 1.90 Micron narrow bands with a spatial resolution of 0.01 pc at a distance of 8 kpc. Here we present an overview of the observations, data reduction, preliminary results, and potential scientific implications, as well as a description of the rationale and design of the survey. We have produced mosaic maps of the Paschen-alpha line and continuum emission, giving an unprecedentedly high resolution and high sensitivity panoramic view of stars and photo-ionized gas in the nuclear environment of the Galaxy. We detect a significant number of previously undetected stars with Paschen-alpha in emission. They are most likely massive stars with strong winds, as confirmed by our initial follow-up spectroscopic observations. About half of the newly detected massive stars are found outside the known clusters (Arches, Quintuplet, and Central). Many previously known diffuse thermal features are now resolved into arrays of intriguingly fine linear filaments indicating a profound role of magnetic fields in sculpting the gas. The bright spiral-like Paschen-alpha emission around Sgr A* is seen to be well confined within the known dusty torus. In the directions roughly perpendicular to it, we further detect faint, diffuse Paschen-alpha emission features, which, like earlier radio images, suggest an outflow from the structure. In addition, we detect various compact Paschen-alpha nebulae, probably tracing the accretion and/or ejection of stars at various evolutionary stages.Comment: accepted for publication in MNRAS; a version of higher resolution images may be found at http://www.astro.umass.edu/~wqd/papers/hst/paper1.pd

Adiabatic orientation of rotating dipole molecules in an external field

The induced polarization of a beam of polar clusters or molecules passing through an electric or magnetic field region differs from the textbook Langevin-Debye susceptibility. This distinction, which is important for the interpretation of deflection and focusing experiments, arises because instead of acquiring thermal equilibrium in the field region, the beam ensemble typically enters the field adiabatically, i.e., with a previously fixed distribution of rotational states. We discuss the orientation of rigid symmetric-top systems with a body-fixed electric or magnetic dipole moment. The analytical expression for their "adiabatic-entry" orientation is elucidated and compared with exact numerical results for a range of parameters. The differences between the polarization of thermodynamic and "adiabatic-entry" ensembles, of prolate and oblate tops, and of symmetric-top and linear rotators are illustrated and identified.Comment: 18 pages, 4 figure

The low-mass Initial Mass Function in the 30 Doradus starburst cluster

We present deep Hubble Space Telescope (HST) NICMOS 2 F160W band observations of the central 56*57" (14pc*14.25pc) region around R136 in the starburst cluster 30 Dor (NGC 2070) located in the Large Magellanic Cloud. Our aim is to derive the stellar Initial Mass Function (IMF) down to ~1 Msun in order to test whether the IMF in a massive metal-poor cluster is similar to that observed in nearby young clusters and the field in our Galaxy. We estimate the mean age of the cluster to be 3 Myr by combining our F160W photometry with previously obtained HST WFPC2 optical F555W and F814W band photometry and comparing the stellar locus in the color-magnitude diagram with main sequence and pre-main sequence isochrones. The color-magnitude diagrams show the presence of differential extinction and possibly an age spread of a few megayears. We convert the magnitudes into masses adopting both a single mean age of 3 Myr isochrone and a constant star formation history from 2 to 4 Myr. We derive the IMF after correcting for incompleteness due to crowding. The faintest stars detected have a mass of 0.5 Msun and the data are more than 50% complete outside a radius of 5 pc down to a mass limit of 1.1 Msun for 3 Myr old objects. We find an IMF of dN/dlog(M) M^(-1.20+-0.2) over the mass range 1.1--20 Msun only slightly shallower than a Salpeter IMF. In particular, we find no strong evidence for a flattening of the IMF down to 1.1 Msun at a distance of 5 pc from the center, in contrast to a flattening at 2 Msun at a radius of 2 pc, reported in a previous optical HST study. We examine several possible reasons for the different results. If the IMF determined here applies to the whole cluster, the cluster would be massive enough to remain bound and evolve into a relatively low-mass globular cluster.Comment: Accepted in ApJ. Abstract abridge

T helper cell polarisation as a measure of the maturation of the immune response.

BACKGROUND: T helper cell polarisation is important under chronic immune stimulatory conditions and drives the type of the evolving immune response. Mice treated with superantigens in vivo display strong effects on Th subset differentiation. The aim of the study was to detect the intrinsic capacity of T cells to polarise under various ex vivo conditions. METHODS: Purified CD4+ T cells obtained from super-antigen-treated mice were cultured under Th polarising conditions in vitro. By combining intracellular cytokine staining and subsequent flow cytometric analysis with quantitative cytokine measurements in culture supernatants by enzyme-linked immunosorbent assay (ELISA), the differential Th polarising capacity of the treatment can be detected in a qualitative and quantitative manner. RESULTS AND CONCLUSIONS: BALB/c mice were shown to be biased to develop strong Th2 polarised immune responses using Th0 stimulation of purified CD4+ T cells from phosphate-buffered saline-treated mice. Nevertheless, our analysis methodology convincingly showed that even in these mice, Toxic Shock Syndrome Toxin-1 treatment in vivo resulted in a significantly stronger Th1 polarising effect than control treatment. Our results indicate that populations of Th cells can be assessed individually for their differential Th1 or Th2 maturation capacity in vivo by analysing robust in vitro polarisation cultures combined with intracellular cytokine staining and ELISA