Come on Baby, Light My Fire: A study on Dutch Millennial Usage of Dating Applications and Morals

This is an explorative study of Dutch Millennials and their usage of mobile dating applications in better understanding the connections between youth culture, technology, and intimate relationships. This research also explores common behaviors and beliefs of a specific age group using generational theory. Five qualitative interviews with Dutch Millennials born between 1983 and 1997. The data from the interviews was analyzed using a generational theory framework, but also in relation to common understanding of the Millennial generation’s characteristics and behaviors. Participants spoke about their identities as Millennials, their relationship with technology and social media, as well as their experiences dating in the 21st century. With the introduction of IT technology early on in their lives, Millennials have come to be defined by their use of tech devices, but strive to find a balance offline. I found that while Dutch Millennials are using mobile dating applications, like Tinder, they are also still using more traditional methods of meeting possible partners in person. This research is important for anyone studying or interested in the rise of online dating, the Millennial generation, or youth cultur

Conceptualizing and Measuring Food Security Among Resettled Refugees Living in the United States

Food security research with resettled refugees in the United States and other Global North countries has found alarmingly high rates of food insecurity, up to 85% of surveyed households. This is well above the current US average of 12.7%. However, the most common survey tool used to measure food security status in the US, the US Household Food Security Survey Module (HFSSM), has not been sufficiently validated for resettled refugee populations, leading to the risk that the HFSSM may actually be underestimating the prevalence of food insecurity among resettled refugees in the US. Though research has attempted to establish validity of the HFSSM for resettled refugees through statistical associations with other risk factors for food insecurity, no efforts have been made to first explore and establish the content validity of the HFSSM for measuring food security among resettled refugees. Content validity is an essential component of construct validity. It first requires a qualitative theoretical foundation for demonstrating the relationships of the test contents to the underlying construct (ie food security) that the test intends to measure. Our research explores these theoretical relationships through a qualitative grounded study of food insecurity and food management experiences described by resettled refugees living in Vermont. Dr. Linda Berlin and I conducted 5 semi-structured focus groups in the summer and fall of 2015 with Bhutanese (2 groups), Somali Bantu (1 group), and Iraqi (2 groups) resettled refugees. During the focus groups, we inquired about food management practices under typical circumstances and under circumstances of limited household resources, as well as difficulties participants have faced in these processes. Additionally, I conducted 18 semi-structured interviews and 1 focus group in the same time frame with service providers who have worked with resettled refugees in capacities primarily related to food, health, and household resources. These interviews provided additional data about context, household food management practices among clients, and triangulating data for the focus groups. A Grounded Theory analysis of the focus group data yielded 5 major emergent themes: 1) Past food insecurity experiences of resettled refugee participants exerted significant influence on the subjective perception of current food insecurity. 2) Barriers other than just financial resources restricted participants’ food security, especially for recently resettled refugees. 3) Preferred foods differed significantly between generations within households. 4) Common elements of quality and quantity included in the definition and measurement of food security did not translate into the languages or experiences of food insecurity among participants. 5) Strategic and adaptive food management practices prevailed among participants, highlighting the temporality and ambiguity of food security concepts. These themes present potential problems of content validity for every HFSSM question. They also reveal the importance of food security concepts that are not covered by the HFSSM, including elements of nutritional adequacy of food, food safety, social acceptability of food and of means of acquiring food, short and long term certainty of food access, and food utilization. I conclude by discussing implications of our findings for service providers and local governments in Vermont who seek to better serve resettled refugee and other New American populations

Characterisation of novel lung cancer cell lines for immuno-inhibitory markers

The present study investigates the expression of immune biomarkers, PD-L1 and HLA-1 on novel lung cancer cell lines (H838, H838-EGFR, A549, A549-ALK, HCC 827, NCI 1650, TWIT, Jacket). PD-L1 and HLA-1 characterisation were initially performed and analysed via flow cytometry. These results showed that the expression of PD-L1 and HLA-1 varies across the cell lines from high percent to low. The effect of IFNy on biomarkers expression was also investigated following a 48 hour incubation period. of the cell lines analysed the expression of PD-L1 increases with IFNy stimulation whilst HLA-1 remains relatively unchanged. Trypan blue assays for cell viability were performed, showing that when stimulated, cells were 100% viable whereas viability decreases upon IFNy exposure

The gauge-relativity of quantum light, matter, and information

We describe the physical relativity of light and matter quantum subsystems, their correlations, and energy exchanges. We examine the most commonly adopted definitions of atoms and photons, noting the significant difference in their localisation properties when expressed in terms of primitive manifestly gauge-invariant and local fields. As a result, different behaviours for entanglement generation and energy exchange occur for different definitions. We explore such differences in detail using toy models of a single photonic mode interacting with one and two dipoles.Comment: This paper is an invited contribution to the Lindblad memorial volume in Open Systems and Information Dynamics. 33 pages, 6 figure

Synthesizing Energy Transitions

This Article assesses the growing and cross-disciplinary literature on energy transitions to explore how it can guide law and policy reforms for the energy sector. The modern conception of energy transition centers primarily on clean energy—a shift away from fossil energy dependence. It also, however, incorporates equity as a core principle, as an increasing emphasis on energy justice and just transition seeks to create guiding norms for the energy sector’s current state of change. The concept of energy transition is critical for describing and giving meaning to a fundamental societal shift at the local, regional, national, and global scales, aligned with the overarching goal enshrined in the Paris Agreement to sharply reduce greenhouse gas emissions contributing to climate change. The energy sector, being among the most significant contributors to global climate change, is not only essential to social and economic functionality and stability broadly but also intimately embedded in everyday life. Accordingly, various disciplines bring different emphases to understandings of transition in the energy context. Our synthesis of this wide-ranging literature demonstrates how the conceptual development of energy transitions across disciplines may enrich the application and depth of this concept in United States policy reform—particularly reforms designed to substantially increase investments in low-carbon energy sources, such as those enacted, for example, by federal legislation in 2021 and 2022

Extensive and anomalous grounding line retreat at Vanderford Glacier, Vincennes Bay, Wilkes Land, East Antarctica

Wilkes Land, East Antarctica, has been losing mass at an accelerating rate over recent decades in response to enhanced oceanic forcing. Overlying the Aurora Subglacial Basin, it has been referred to as the ‘weak underbelly’ of the East Antarctic Ice Sheet and is drained by several major outlet glaciers. Despite their potential importance, few of these glaciers have been studied in detail. This includes the six outlet glaciers which drain into Vincennes Bay, a region recently discovered to have the warmest intrusions of modified Circumpolar Deep Water (mCDW) ever recorded in East Antarctica. Here, we use remotely sensed optical imagery, differential satellite aperture radar interferometry (DInSAR) and datasets of ice surface velocity, ice surface elevation and grounding line position, to investigate ice dynamics between 1963 and 2022. Decadal trends in frontal position are observed across the Vincennes Bay outlet glaciers, potentially correlated to variations in sea ice production. Ice surface velocities were generally stable between 2000 and 2021, with some fluctuations measured across the grounding line of Bond East Glacier. Changes in ice surface elevation were spatially variable, but a clear and consistent thinning trend was measured at Vanderford Glacier between 2003 and 2020. Enhanced rates of ice thinning were seen across each of the Vanderford, Adams, Anzac, and Underwood Glaciers between 2017 and 2020. Most importantly, our results confirm extensive grounding line retreat at Vanderford Glacier, measured at 18.6 km between 1996 and 2020. Such rapid grounding line retreat (0.8 km yr-1) is consistent with the notion that warm mCDW is able to access deep cavities formed below the Vanderford Ice Shelf, driving high rates of basal melting. With a retrograde slope observed inland along the Vanderford Trench, such oceanic forcing may have significant implications for the future stability of Vanderford Glacier

Chance of healthy versus adverse outcome in subsequent pregnancy after previous loss beyond 16 weeks: data from a specialized follow-up clinic

PURPOSE: Women with a previous fetal demise have a 2-20 fold increased risk of another stillbirth in a subsequent pregnancy when compared to those who have had a live birth. Despite this, there is limited research regarding the management and outcomes of subsequent pregnancies. This study was conducted to accurately quantify the chances of a woman having a healthy subsequent pregnancy after a pregnancy loss. METHODS: A retrospective study was conducted at a tertiary-level unit between March 2019 and April 2021. We collected data on all women with a history of previous fetal demise attending a specialized perinatal history clinic and compared the risk of subsequent stillbirth to those with a normal pregnancy outcome. Outcome data included birth outcome, obstetric and medical complications, gestational age and birth weight and mode of delivery. Those who had healthy subsequent pregnancies were compared with those who experienced adverse outcomes. RESULTS: A total of 101 cases were reviewed. Ninety-six women with subsequent pregnancies after a history of fetal demise from 16 weeks were included. Seventy-nine percent of women (n = 76) delivered a baby at term, without complications. Overall, 2.1% had repeat pregnancy losses (n = 2) and 2.1% delivered babies with fetal growth restriction (n = 2). There were no cases of abruption in a subsequent pregnancy. Eighteen neonates were delivered prematurely (18.4%), 15 of these (83.3%) were due to iatrogenic causes and three (16.7%) were spontaneous. In univariable logistic regression analyses, those with adverse outcomes in subsequent pregnancies had greater odds of pre-eclampsia (Odds ratio *(OR) = 3.89, 95% CI = 1.05-14.43, p = .042) and fetal growth restriction (OR = 4.58, 95% CI = 1.41-14.82, p = 0.011) in previous pregnancies compared to those with healthy outcomes. However, in multivariable logistic regression analyses, neither variable had a significant odds ratio (OR = 2.03, 95% CI = 0.44-9.39, p = .366 and OR = 3.42, 95% CI = 0.90 - 13.09, p = .072 for pre-eclampsia and FGR, respectively). CONCLUSION: Four in five women had a healthy subsequent pregnancy. This is a reassuring figure for women when contemplating another pregnancy, particularly if cared for in a specialist clinic

The impact of COVID-19 related disruption on injury rates in elite men’s domestic cricket

This study aimed to investigate the impact of COVID-19 enforced prolonged training disruption and shortened competitive season, on in-season injury and illness rates. Injury incidence and percent proportion was calculated for the 2020 elite men's senior domestic cricket season and compared to a historical average from five previous regular seasons (2015 to 2019 inclusive). The injury profile for the shortened 2020 season was generally equivalent to what would be expected in a regular season, except for a significant increase in medical illness as a proportion of time loss (17% compared to historic average of 6%) and in-season days lost (9% compared to historic average of 3%) due to COVID-19 related instances (most notably precautionary isolation due to contact with a confirmed or suspected COVID-19 case). There was a significant increase in the proportion of in-season days lost to thigh injuries (24% compared to 9%) and a significant decrease in the proportion of days lost to hand (4% compared to 12%) and lumbar spine (7% compared to 21%) injuries. These findings enhance understanding of the impact prolonged period of training disruption and shortened season can have on cricket injuries and the challenges faced by practitioners under such circumstances.</p

Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States

Loading of skeletal muscle changes the tissue phenotype reflecting altered metabolic and functional demands. In humans, heterogeneous adaptation to loading complicates the identification of the underpinning molecular regulators. A within-person differential loading and analysis strategy reduces heterogeneity for changes in muscle mass by ∼40% and uses a genome-wide transcriptome method that models each mRNA from coding exons and 3′ and 5′ untranslated regions (UTRs). Our strategy detects ∼3–4 times more regulated genes than similarly sized studies, including substantial UTR-selective regulation undetected by other methods. We discover a core of 141 genes correlated to muscle growth, which we validate from newly analyzed independent samples (n = 100). Further validating these identified genes via RNAi in primary muscle cells, we demonstrate that members of the core genes were regulators of protein synthesis. Using proteome-constrained networks and pathway analysis reveals notable relationships with the molecular characteristics of human muscle aging and insulin sensitivity, as well as potential drug therapies

Tree Planting in Prince George’s County, Maryland: Case Studies and Benefits Assessment in Four Parks

Final project for LARC452: Green Infrastructure and Community Greening (Fall 2019). University of Maryland, College Park.The benefits of trees and forests and the ecosystems services that they provide is well documented. Ecosystems services include carbon sequestration, stormwater retention, water pollution reduction, air pollution retention and others. In addition, tree planting efforts provide numerous social benefits including improvement of community cohesion, increase in social capital, and environmental stewardship and education. In order to provide a greater understanding of tree planting efforts and assessing tree benefits locally, two major project components were undertaken: 1) the research and documentation using case studies of individual tree planting efforts, and 2) assessment of benefits of recent and proposed trees for four selected parks in Prince George’s county.Prince George's Count