51 research outputs found
The Corporate Tax Reform of 2008: Germanyâs Answer to Globalisation â or just Patchwork?
ISSN:1612-066
Die Unternehmensteuerreform 2008: Deutschlands Antwort auf die Globalisierung â oder doch ein StĂŒckwerk?
ISSN:0018-974XISSN:2199-445
Bovine pericardium based non-cross linked collagen matrix for successful root coverage, a clinical study in human
Introduction: The aim of this study was to clinically assess the capacity of a novel bovine pericardium based, non-cross linked collagen matrix in root coverage.
Methods: 62 gingival recessions of Miller class I or II were treated. The matrix was adapted underneath a coronal repositioned split thickness flap. Clinical values were assessed at baseline and after six months.
Results: The mean recession in each patient was 2.2 mm at baseline. 6 Months after surgery 86.7% of the exposed root surfaces were covered. On average 0,3 mm of recession remained. The clinical attachment level changed from 3.5 ± 1.3 mm to 1,8 ( ± 0,7) mm during the observational time period. No statistically significant difference was found in the difference of probing depth. An increase in the width of gingiva was significant. With a baseline value of 1.5 ± 0.9 mm an improvement of 2.4 ± 0.8 mm after six month could be observed. 40 out of 62 recessions were considered a thin biotype at baseline. After 6 months all 62 sites were assessed thick.
Conclusions: The results demonstrate the capacity of the bovine pericardium based non-cross linked collagen matrix for successful root coverage. This material was able to enhance gingival thickness and the width of keratinized gingiva. The percentage of root coverage achieved thereby is comparable to existing techniques. This method might contribute to an increase of patient's comfort and an enhanced aesthetical outcome
Contributions and perspectives of Indigenous Peoples to the study of mercury in the Arctic
Arctic Indigenous Peoples are among the most exposed humans when it comes to foodborne mercury (Hg). In response,
Hg monitoring and research have been on-going in the circumpolar Arctic since about 1991; this work has been mainly
possible through the involvement of Arctic Indigenous Peoples. The present overview was initially conducted in the
context of a broader assessment of Hg research organized by the Arctic Monitoring and Assessment Programme.
This article provides examples of Indigenous Peoples' contributions to Hg monitoring and research in the Arctic, and
discusses approaches that could be used, and improved upon, when carrying out future activities. Over 40 mercury
projects conducted with/by Indigenous Peoples are identified for different circumpolar regions including the U.S.,
Canada, Greenland, Sweden, Finland, and Russia as well as instances where Indigenous Knowledge contributed to
the understanding of Hg contamination in the Arctic. Perspectives and visions of future Hg research as well as recommendations are presented. The establishment of collaborative processes and partnership/co-production approaches
with scientists and Indigenous Peoples, using good communication practices and transparency in research activities,
are key to the success of research and monitoring activities in the Arctic. Sustainable funding for community-driven
monitoring and research programs in Arctic countries would be beneficial and assist in developing more research/
monitoring capacity and would promote a more holistic approach to understanding Hg in the Arctic. These activities
should be well connected to circumpolar/international initiatives to ensure broader availability of the information and
uptake in policy development
The changing global distribution and prevalence of canine transmissible venereal tumour.
BACKGROUND: The canine transmissible venereal tumour (CTVT) is a contagious cancer that is naturally transmitted between dogs by the allogeneic transfer of living cancer cells during coitus. CTVT first arose several thousand years ago and has been reported in dog populations worldwide; however, its precise distribution patterns and prevalence remain unclear. RESULTS: We analysed historical literature and obtained CTVT prevalence information from 645 veterinarians and animal health workers in 109 countries in order to estimate CTVT's former and current global distribution and prevalence. This analysis confirmed that CTVT is endemic in at least 90 countries worldwide across all inhabited continents. CTVT is estimated to be present at a prevalence of one percent or more in dogs in at least 13 countries in South and Central America as well as in at least 11 countries in Africa and 8 countries in Asia. In the United States and Australia, CTVT was reported to be endemic only in remote indigenous communities. Comparison of current and historical reports of CTVT indicated that its prevalence has declined in Northern Europe, possibly due to changes in dog control laws during the nineteenth and twentieth centuries. Analysis of factors influencing CTVT prevalence showed that presence of free-roaming dogs was associated with increased CTVT prevalence, while dog spaying and neutering were associated with reduced CTVT prevalence. Our analysis indicated no gender bias for CTVT and we found no evidence that animals with CTVT frequently harbour concurrent infectious diseases. Vincristine was widely reported to be the most effective therapy for CTVT. CONCLUSIONS: Our results provide a survey of the current global distribution of CTVT, confirming that CTVT is endemic in at least 90 countries worldwide. Additionally, our analysis highlights factors that continue to modify CTVT's prevalence around the world and implicates free-roaming dogs as a reservoir for the disease. Our analysis also documents the disappearance of the disease from the United Kingdom during the twentieth century, which appears to have been an unintentional result of the introduction of dog control policies.This is the author's accepted manuscript. The final version of this article has been published by BioMed Central: http://www.biomedcentral.com/1746-6148/10/168
Severe Bone Loss as Part of the Life History Strategy of Bowhead Whales.
The evolution of baleen constituted a major evolutionary change that made it possible for baleen whales to reach enormous body sizes while filter feeding on tiny organisms and migrating over tremendous distances. Bowhead whales (Balaena mysticetus) live in the Arctic where the annual cycle of increasing and decreasing ice cover affects their habitat, prey, and migration. During the nursing period, bowheads grow rapidly; but between weaning and approximately year 5, bowhead whales display sustained baleen and head growth while limiting growth in the rest of their bodies. During this period, they withdraw resources from the skeleton, in particular the ribs, which may lose 40% of bone mass. Such dramatic changes in bones of immature mammals are rare, although fossil cetaceans between 40 and 50 million years ago show an array of rib specializations that include bone loss and are usually interpreted as related to buoyancy control
Effect of ridge preservation for early implant placement - is there a need to remove the biomaterial?
AIM To assess (i) bone regeneration around implants placed early in sites with or without ridge preservation and (ii) if the bone substitute material (DBBM-C) has to be removed at implant placement. MATERIALS AND METHODS In eight beagle dogs, three sites were randomly assigned to ridge preservation (DBBM-C plus collagen matrix (CMX)) (two sites; RP) or spontaneous healing (1 site; SH). Four weeks later, in one of the RP sites, dental implants were placed without removing the DBBM-C (RP1), whereas in RP2 and SH sites all non-integrated DBBM-C and/or granulation tissue were removed before implant placement and concomitant GBR. Histomorphometric outcomes were assessed at 4 and 12 weeks. RESULTS The median buccal fBIC (first bone-to-implant contact) was located more apical in groups RP1: 1.34 mm (0.09; 2.96) and RP2: 1.41 mm (0.54; 2.72) than in group SH: 0.79 mm (0.26; 1.50) (p = 0.452) at 4 weeks. At 12 weeks, median buccal fBIC values were for RP1: 0.88 mm (0.00; 2.33), for RP2: 0.16 mm (0.00; 1.33) and for SH: 0.00 mm (0.00; 0.98) (p = 0.362). BIC values increased over 12 weeks in all groups. CONCLUSIONS Ridge preservation followed by early implant placement led to higher BIC values at 12 than at 4 weeks. There is no need to remove the biomaterial at implant placement to ensure osseointegration. No relevant differences were observed between the three groups for any outcome measure
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