2,052 research outputs found
Effect of Resin Molecular Weight on Bonding Flakeboard
Information on the effect of resin molecular weight on flakeboard properties is limited. A commercial phenol formaldehyde flakeboard resin was separated into two molecular weight fractions by diafiltration. Aspen flakeboards were prepared with the different resin fractions. Penetration characteristics of the different fractions were determined microscopically. Results indicate that both low and high molecular weight components of the resin are needed to achieve optimum board properties
Pyla-Vigla: A Case Study Assessing the Imperial Strategies of the Hellenistic Diadochoi in Cyprus
The aim of the present study is to examine the mechanisms the Diadochoi implemented to gain and maintain control over Cyprus using Pyla-Vigla, a recently discovered fortified garrison, as a case study. Alexander the Great’s successors faced a seemingly insurmountable problem: How does one govern, control, and maintain the largest territorial empire the world had ever seen? Alexander’s imperial strategy was predicated upon maintaining native governing institutions of newly subjugated lands and appointing new leaders. This system could not work for the Diadochoi because without a clear path to succession, a twenty-nine-year period of incessant conflict ensued throughout the Eastern Mediterranean. The surviving successors adopted various strategies to exercise imperial authority over their rivals, which ultimately led to the creation of three ruling Hellenistic dynasties: Ptolemies, Seleucids, and Antigonids. Pyla-Vigla represents one of many such strategies
High-Level Macrolide Resistance Due to the Mega Element [mef(E)/mel] in Streptococcus pneumoniae
Transferable genetic elements conferring macrolide resistance in Streptococcus pneumoniae can encode the efflux pump and ribosomal protection protein, mef(E)/mel, in an operon of the macrolide efflux genetic assembly (Mega) element- or induce ribosomal methylation through a methyltransferase encoded by erm(B). During the past 30 years, strains that contain Mega or erm(B) or both elements on Tn2010 and other Tn916-like composite mobile genetic elements have emerged and expanded globally. In this study, we identify and define pneumococcal isolates with unusually high-level macrolide resistance (MICs > 16 μg/ml) due to the presence of the Mega element [mef(E)/mel] alone. High-level resistance due to mef(E)/mel was associated with at least two specific genomic insertions of the Mega element, designated Mega-2.IVa and Mega-2.IVc. Genome analyses revealed that these strains do not possess erm(B) or known ribosomal mutations. Deletion of mef(E)/mel in these isolates eliminated macrolide resistance. We also found that Mef(E) and Mel of Tn2010-containing pneumococci were functional but the high-level of macrolide resistance was due to Erm(B). Using in vitro competition experiments in the presence of macrolides, high-level macrolide-resistant S. pneumoniae conferred by either Mega-2.IVa or erm(B), had a growth fitness advantage over the lower-level, mef(E)/mel-mediated macrolide-resistant S. pneumoniae phenotypes. These data indicate the ability of S. pneumoniae to generate high-level macrolide resistance by macrolide efflux/ribosomal protection [Mef(E)/Mel] and that high-level resistance regardless of mechanism provides a fitness advantage in the presence of macrolides
The Mothball, Sustainment, and Proposed Reactivation of the Hypersonic Tunnel Facility (HTF) at NASA Glenn Research Center Plum Brook Station
The Hypersonic Tunnel Facility (HTF) located at the NASA Glenn Research Center s Plum Brook Station in Sandusky, Ohio, is the nation s only large-scale, non-vitiated, hypersonic propulsion test facility. The HTF, with its 4-story graphite induction heater, is capable of duplicating Mach 5, 6, and 7 flight conditions. This unique propulsion system test facility has experienced several standby and reactivation cycles. The intent of the paper is to overview the HTF capabilities to the propulsion community, present the current status of HTF, and share the lessons learned from putting a large-scale facility into mothball status for a later restar
Composite mobile genetic elements disseminating macrolide resistance in Streptococcus pneumoniae
Active Vibration Control Device
An active vibration control device for controlling vibration in a cantilevered member and a method for the same are disclosed. The device is comprised of a cantilevered member having a longitudinal axis comprising a sensor mounted near the free end of the member to measure motion of the member in a transverse direction and to produce a corresponding signal. A force generating assembly is mounted to the member near the free end to oppose the measured motion with a force thereby minimizing subsequent motion along the transverse axis caused by vibration
A regional analysis of tide-surge interactions during extreme water levels in complex coastal systems of Aotearoa New Zealand
Tide-surge interaction (TSI) is a critical factor in assessing flooding in shallow coastal systems, particularly in estuaries and harbours. Non-linear interactions between tides and surges can occur due to the water depth and bed friction. Global investigations have been conducted to examine TSI, but its occurrence and impact on water levels in Aotearoa New Zealand (NZ) have not been extensively studied. Water level observations from 36 tide gauges across the diverse coast of NZ were analysed to determine the occurrence and location of TSI. Statistical analysis and numerical modelling were conducted on data from both inside and outside estuaries, focusing on one estuary (Manukau Harbour) to determine the impact of TSI and estuarine morphology on the co-occurrence rate of extreme events. TSI was found to occur at most sites in NZ and primarily affects the timing of the largest surges relative to high tide. There were no regional patterns associated with the tide, non-tidal residual, or skew-surge regimes. The strongest TSI occurred in inner estuarine locations and was correlated with the intertidal area. The magnitude of the TSI varied depending on the method used, ranging from -16 cm to +27 cm. Co-occurrence rates of extreme water levels outside and inside the same estuary varied from 20% to 84%, with TSI modulating the rate by affecting tidal amplification. The results highlight the importance of investing in a more extensive tide gauge network to provide longer observations in highly populated estuarine coastlines. The incorporation of TSI in flooding hazard projections would benefit from more accurate and detailed observations, particularly in estuaries with high morphological complexity. TSI occurs in most sites along the coast of NZ and has a significant impact on water levels in inner estuarine locations. TSI modulates the co-occurrence rate of extreme water levels in estuaries of NZ by affecting tidal amplification. Therefore, further investment in the tide gauge network is needed to provide more accurate observations to incorporate TSI in flooding hazard projections
Incidence and progression of mild aortic regurgitation after Tirone David reimplantation valve-sparing aortic root replacement
ObjectiveThe study objective was to determine whether recurrent or residual mild aortic regurgitation, which occurs after valve-sparing aortic root replacement, progresses over time.MethodsBetween 2003 and 2008, 154 patients underwent Tirone David-V valve-sparing aortic root replacement; 96 patients (62%) had both 1-year (median, 12 ± 4 months) and mid-term (62 ± 22 months) transthoracic echocardiograms available for analysis. Age of patients averaged 38 ± 13 years, 71% were male, 31% had a bicuspid aortic valve, 41% had Marfan syndrome, and 51% underwent aortic valve repair, predominantly cusp free margin shortening.ResultsForty-one patients (43%) had mild aortic regurgitation on 1-year echocardiogram. In 85% of patients (n = 35), mild aortic regurgitation remained stable on the most recent echocardiogram (median, 57 ± 20 months); progression to moderate aortic regurgitation occurred in 5 patients (12%) at a median of 28 ± 18 months and remained stable thereafter; severe aortic regurgitation developed in 1 patient, eventually requiring reoperation. Five patients (5%) had moderate aortic regurgitation at 1 year, which did not progress subsequently. Two patients (2%) had more than moderate aortic regurgitation at 1 year, and both ultimately required reoperation.ConclusionsAlthough mild aortic regurgitation occurs frequently after valve-sparing aortic root replacement, it is unlikely to progress over the next 5 years and should not be interpreted as failure of the valve-preservation concept. Further, we suggest that mild aortic regurgitation should not be considered nonstructural valve dysfunction, as the 2008 valve reporting guidelines would indicate. We need 10- to 15-year follow-up to learn the long-term clinical consequences of mild aortic regurgitation early after valve-sparing aortic root replacement
The nature of iron-oxygen vacancy defect centers in PbTiO3
The iron(III) center in ferroelectric PbTiO3 together with an oxygen vacancy
forms a charged defect associate, oriented along the crystallographic c-axis.
Its microscopic structure has been analyzed in detail comparing results from a
semi-empirical Newman superposition model analysis based on finestructure data
and from calculations using density functional theory.
Both methods give evidence for a substitution of Fe3+ for Ti4+ as an acceptor
center. The position of the iron ion in the ferroelectric phase is found to be
similar to the B-site in the paraelectric phase. Partial charge compensation is
locally provided by a directly coordinated oxygen vacancy.
Using high-resolution synchrotron powder diffraction, it was verified that
lead titanate remains tetragonal down to 12 K, exhibiting a c/a-ratio of
1.0721.Comment: 11 pages, 5 figures, accepted in Phys. Rev.
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