1,543 research outputs found
On the Optimal Choice of Spin-Squeezed States for Detecting and Characterizing a Quantum Process
Quantum metrology uses quantum states with no classical counterpart to
measure a physical quantity with extraordinary sensitivity or precision. Most
metrology schemes measure a single parameter of a dynamical process by probing
it with a specially designed quantum state. The success of such a scheme
usually relies on the process belonging to a particular one-parameter family.
If this assumption is violated, or if the goal is to measure more than one
parameter, a different quantum state may perform better. In the most extreme
case, we know nothing about the process and wish to learn everything. This
requires quantum process tomography, which demands an informationally-complete
set of probe states. It is very convenient if this set is group-covariant --
i.e., each element is generated by applying an element of the quantum system's
natural symmetry group to a single fixed fiducial state. In this paper, we
consider metrology with 2-photon ("biphoton") states, and report experimental
studies of different states' sensitivity to small, unknown collective SU(2)
rotations ("SU(2) jitter"). Maximally entangled N00N states are the most
sensitive detectors of such a rotation, yet they are also among the worst at
fully characterizing an a-priori unknown process. We identify (and confirm
experimentally) the best SU(2)-covariant set for process tomography; these
states are all less entangled than the N00N state, and are characterized by the
fact that they form a 2-design.Comment: 10 pages, 5 figure
Adaptive quantum state tomography improves accuracy quadratically
We introduce a simple protocol for adaptive quantum state tomography, which
reduces the worst-case infidelity between the estimate and the true state from
to . It uses a single adaptation step and just one
extra measurement setting. In a linear optical qubit experiment, we demonstrate
a full order of magnitude reduction in infidelity (from to ) for
a modest number of samples ().Comment: 8 pages, 7 figure
The Long Crisis: Economic Inequality in New York City
City University of New York Law Review hosted this public panel discussion on November 12, 2014 at CUNY School of Law. CUNY Law Review would like to thank the co-sponsors of this event: Law Students for Reproductive Justice (LSRJ); Latin American Law Students Association (LALSA); Labor Coalition for Workers’ Rights and Economic Justice; National Lawyers Guild CUNY Law Chapter (NLG); Iraqi Refugee Assistance Project (IRAP); Student for Justice in Palestine (SJP) and CUNY Law Association of Students for Housing (CLASH)
Predictive Criterion Validity of the Parsley Symptom index against the Patient-Reported Outcomes Measurement information System-10 in a Chronic Disease Cohort: Retrospective Cohort Study
BACKGROUND: Approximately 60% of US adults live with chronic disease, imposing a significant burden on patients and the health care system. With the rise of telehealth, patient-reported outcomes measures (PROMs) have emerged as pivotal tools for managing chronic disease. While numerous PROMs exist, few have been designed explicitly for telehealth settings. The Parsley Symptom Index (PSI) is an electronic patient-reported outcome measure (ePROM) developed specifically for telehealth environments.
OBJECTIVE: Our aim is to determine whether the PSI predicts changes in the established Patient-Reported Outcomes Measurement Information System-10 (PROMIS-10) Global Health, a 10-question short form.
METHODS: We conducted a retrospective cohort study using data from 367 unique patients, amassing 1170 observations between August 30, 2017, and January 30, 2023. Patients completed the PSI and the PROMIS-10 multiple times throughout the study period. Using univariate regression models, we assess the predictive criterion validity of the PSI against PROMIS-10 scores.
RESULTS: This study revealed significant relationships between the PSI and PROMIS-10 physical and mental health scores through comprehensive univariate analyses, thus establishing support for the criterion validity of the PSI. These analyses highlighted the PSI\u27s potential as an insightful tool for understanding and predicting both mental and physical health dimensions.
CONCLUSIONS: Our findings emphasize the importance of the PSI in capturing the nuanced interactions between symptomatology and health outcomes. These insights reinforce the value of the PSI in clinical contexts and support its potential as a versatile tool in both research and practice
Zymogen granules of mouse parotid acinar cells are acidified in situ in an ATP-dependent manner
The mechanism for acidification of zymogen granules in acinar cells of mouse parotid gland was explored using acridine orange, lysosomotropic agents, and an inhibitor of cellular ATP production. Methylamine and monensin reversibly collapsed the pH gradient of granules without affecting cellular ATP levels. Depletion of cellular ATP with antimycin A did not collapse the pH gradient. However, recovery of acidity in the granules, after collapse of the pH gradient by methylamine, was blocked by depletion of cellular ATP. These results demonstrate that zymogen granules of parotid gland are acidic in situ and that ATP is required for acidification of the granules.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47684/1/441_2004_Article_BF00221764.pd
Environmental enrichment as a therapy for autism: A clinical trial replication and extension.
Based on work done in animal models showing that autism-like symptoms are ameliorated following exposure to an enriched sensorimotor environment, we attempted to develop a comparable therapy for children with autism. In an initial randomized controlled trial, children with autism who received sensorimotor enrichment at home for six months had significant improvements in both their cognitive ability and the severity of their autism symptoms (Woo & Leon, 2013). We now report the outcomes of a similar randomized controlled trial in which children with autism, aged 3-6 years old, were randomly assigned to groups that received either daily sensorimotor enrichment, administered by their parents, along with standard care, or they received standard care alone. After six months, enriched children showed statistically significant gains in their IQ scores, a decline in their atypical sensory responses, and an improvement in their receptive language performance, compared to controls. Furthermore, after six months of enrichment therapy, 21% of the children who initially had been given an autism classification, using the Autism Diagnostic Observation Schedule, improved to the point that, although they remained on the autism spectrum, they no longer met the criteria for classic autism. None of the standard care controls reached an equivalent level of improvement. Finally, the outcome measures for children who received only a subset of sensory stimuli were similar to those receiving the full complement of enrichment exercises. Sensorimotor enrichment therapy therefore appears to be a cost-effective means of treating a range of symptoms for children with autism
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