Assessing meaning in life on an international scale: Psychometric evidence for the Meaning in Life Questionnaire-Short Form among Chilean households

Several research projects have endeavored to articulate parsimonious and comprehensive accounts of wellbeing. A set of core concepts is seen to be emerging, including the psychological wellbeing module of the Oxford Poverty and Human Development Initiative’s international research on poverty. One of the core components of wellbeing according to this initiative and others is meaning in life. The present study focuses on a psychometric evaluation of a short measure of meaning in life to be used in international measurement of wellbeing, using data from a nationally-representative sample of households in Chile (N = 1,997). The factor structure of the Meaning in Life Questionnaire-Short Form (MLQ-SF) was confirmed, and shown to be invariant across gender and age. The items of the MLQ-SF formed a factor that was distinct from the items of other wellbeing measures that were assessed (psychological needs, life satisfaction, and domain satisfaction). Scores on the MLQ-SF were reliable in this sample, and correlated in the expected directions with other wellbeing indicators. We conclude that the MLQ-SF shows distinct promise as a measure of a core component of wellbeing—meaning in life—in international research.

The role of intolerance of uncertainty in the relationship between daily search for and presence of meaning in life

People who are highly intolerant of uncertainty have a propensity to fear the unknown, which influences perceptions and desires for control and predictability (Carleton, 2016). Processes related to searching for and maintaining meaning might deviate based on intolerance of uncertainty as meaning-making can be spurred by breakdowns in one’s sense of understanding or predictability (Park, 2010). The current study was designed to examine within-person relationships between daily search for and presence of meaning, while investigating how people’s intolerance of uncertainty (IU) influences the search-presence relationship. During a three-week daily diary study, results showed that daily search significantly predicted same-day presence and presence the following day. IU significantly moderated the effects of search on presence such that people who were highly intolerant of uncertainty experienced less presence when they engaged in searching than low IU participants. Results suggest researchers should consider the potential consequences of IU in limiting the development of a vital well-being resource, presence of meaning

Meaning in life: One link in the chain from religiousness to well-being

Meaning in life has been identified as a potential mediator of the link between religiousness and psychological health. The authors tested this hypothesis in 2 studies, using multiple methods and measures of religiousness and well-being. In the studies, meaning in life mediated the relation between religiousness and life satisfaction (Study 1A), as well as self-esteem and optimism (Study 1B). In addition, using an experience sampling method, the authors found that meaning in life also mediated the relation between daily religious behaviors and well-being (Study 2). The authors discuss these findings and suggest that meaning in life may be an effective conduit through which counselors and clients can discuss "ultimate" matters, even when they do not share similar perspectives on religion

Import of ADP/ATP carrier into mitochondria

We have identified the yeast homologue of Neurospora crassa MOM72, the mitochondrial import receptor for the ADP/ATP carrier (AAC), by functional studies and by cDNA sequencing. Mitochondria of a yeast mutant in which the gene for MOM72 was disrupted were impaired in specific binding and import of AAC. Unexpectedly, we found a residual, yet significant import of AAC into mitochondria lacking MOM72 that occurred via the receptor MOM19. We conclude that both MOM72 and MOM19 can direct AAC into mitochondria, albeit with different efficiency. Moreover, the precursor of MOM72 apparently does not require a positively charged sequence at the extreme amino terminus for targeting to mitochondria

Randomized trial of a calling-infused career work shop incorporating counselor self-disclosure.

a b s t r a c t A randomized controlled trial was used to test (1) the efficacy of a two-session career development workshop for college student participants; (2) the effect of counselor self-disclosure on outcomes; and (3) the effect of infusing calling and vocation concepts on outcomes. Both standard (person-environment fit) and calling/vocation-infused interventions improved career decision self-efficacy relative to a wait-list control. Counselor self-disclosure also increased participant career decision self-efficacy in both conditions and increased appraisals of meaning in life for participants in calling/vocationinfused workshops. Incorporating considerations of calling and vocation neither detracted from nor added to workshop effectiveness. Career development workshops were supported, as was the use of moderate counselor self-disclosure. Suggestions for career counseling practice and intervention research are discussed

Meaning in life: Is it a protective factor for adolescents’ psychological health

Abstract Background Searching for a coherent meaning in life has long been proposed to be a protective factor in adolescent development

Validation of the Subtle and Blatant Racism Scale for Asian American College Students (SABR-A 2 )

This investigation describes the validation of a measure of perceived racism developed to assess racial experiences of Asian American college students. In three studies across two different regions of the United States, there was strong evidence for the validation of the 8-item Subtle and Blatant Racism Scale for Asian American College Students (SABR-A 2 ). The subtle racism subscale refers to instances of discrimination attributable implicitly to racial bias or stereotype, whereas the blatant racism subscale refers to instances of discrimination attributable explicitly to racial bias or stereotype. The two-subscale structure of the SABR-A 2 was supported by exploratory and confirmatory factor analyses and demonstrated discriminant, convergent, and incremental validity, as well as internal reliability and stability over 2 weeks

Assessing the Influence of Reversed Items and Force-Choice on the Work and Meaning Inventory [Evaluación de la influencia de los ítems invertidos y de elección forzosa en el Inventario de trabajo significativo]

AbstractResponse biases are issues in inventories in positive organizational psychology. The study aims to control the response bias in the assessment of meaning of work through two methods: reversed key items and forced-choice format. The sample consisted of 351 professionals; women constituted 60.0 % of the sample. The participants answered two versions of the instrument for meaning of work: Likert-type items and forced-choice. For both versions, the unifactorial model was the most appropriate for the data available. The results indicate that the random intercepts model fit the Likert data (CFI = .92), as well as the forced-choice model (CFI = .97). Besides, the latent dimension of the forced-choice version did not correlate with acquiescence index (r < .08; p > .05), and approximately 20 % of the variance of the items might be due to the method (Likert or forced-choice). The present study illustrates the importance of response bias control in self-report instruments. ResumenLos sesgos de respuesta son problemas en los inventarios de la psicología organizacional positiva. El estudio tiene como objetivo controlar el sesgo de respuesta en la eva­luación del trabajo significativo a través de dos métodos: ítems clave invertidos y formato de elección forzosa. La muestra estuvo formada por 351 profesionales; las muje­res constituyeron el 60.0 % de la muestra. Los participan­tes respondieron dos versiones del instrumento de signifi­cado del trabajo: ítems tipo Likert y elección forzosa. Para ambas versiones, el modelo unifactorial fue el más apro­piado para los datos disponibles. Los resultados indican que el modelo de intersecciones aleatorias se ajusta a los datos Likert (CFI = .92), así como al modelo de elección forzada (CFI = .97). Además, la dimensión latente de la versión de elección forzada no se correlacionó con el ín­dice de aquiescencia (r < .08; p > .05), y aproximada­mente el 20 % de la varianza de los ítems podría deberse al método (Likert o forzado). elección). El presente estu­dio ilustra la importancia del control del sesgo de res­puesta en los instrumentos de autoinforme

Tourism and Economic Globalization: An Emerging Research Agenda

Globalization characterizes the economic, social, political, and cultural spheres of the modern world. Tourism has long been claimed as a crucial force shaping globalization, while in turn the developments of the tourism sector are under the influences of growing interdependence across the world. As globalization proceeds, destination countries have become more and more susceptible to local and global events. By linking the existing literature coherently, this study explores a number of themes on economic globalization in tourism. It attempts to identify the forces underpinning globalization and assess the implications on both the supply side and the demand side of the tourism sector. In view of a lack of quantitative evidence, future directions for empirical research have been suggested to investigate the interdependence of tourism demand, the convergence of tourism productivity, and the impact of global events

Predicting for activity of second-line trastuzumab-based therapy in her2-positive advanced breast cancer

<p>Abstract</p> <p>Background</p> <p>In Her2-positive advanced breast cancer, the upfront use of trastuzumab is well established. Upon progression on first-line therapy, patients may be switched to lapatinib. Others however remain candidates for continued antibody treatment (treatment beyond progression). Here, we aimed to identify factors predicting for activity of second-line trastuzumab-based therapy.</p> <p>Methods</p> <p>Ninety-seven patients treated with > 1 line of trastuzumab-containing therapy were available for this analysis. Her2-status was determined by immunohistochemistry and re-analyzed by FISH if a score of 2+ was gained. Time to progression (TTP) on second-line therapy was defined as primary study endpoint. TTP and overall survival (OS) were estimated using the Kaplan-Meier product limit method. Multivariate analyses (Cox proportional hazards model, multinomial logistic regression) were applied in order to identify factors associated with TTP, response, OS, and incidence of brain metastases. <it>p </it>values < 0.05 were considered to indicate statistical significance.</p> <p>Results</p> <p>Median TTP on second-line trastuzumab-based therapy was 7 months (95% CI 5.74-8.26), and 8 months (95% CI 6.25-9.74) on first-line, respectively (n.s.). In the multivariate models, none of the clinical or histopthological features could reliably predict for activity of second-line trastuzumab-based treatment. OS was 43 months suggesting improved survival in patients treated with trastuzumab in multiple-lines. A significant deterioration of cardiac function was observed in three patients; 40.2% developed brain metastases while on second-line trastuzumab or thereafter.</p> <p>Conclusion</p> <p>Trastuzumab beyond progression showed considerable activity. None of the variables investigated correlated with activity of second-line therapy. In order to predict for activity of second-line trastuzumab, it appears necessary to evaluate factors known to confer trastuzumab-resistance.</p