Community Service and Service-learning in America's Schools

"In the spring of 2008, 1,847 principals of K-12 public schools, nationwide, responded to a survey on the prevalence of community service and service-learning in their schools. The National Study of the Prevalence of Community Service and Service-Learning in K-12 Public Schools, sponsored by the Corporation for National and Community Service and conducted by Westat, collected data on the scope of community service and service-learning activities, as well as the policies and supports for service-learning provided by and for schools during the 2007-08 academic year.

Leveling the Path to Participation: Volunteering and Civic Engagement Among Youth From Disadvantaged Circumstances

This report is the third in the Youth Helping America Series, a series of reports based on data from the 2005 Youth Volunteering and Civic Engagement Survey, a national survey of 3,178 American youth between the ages of 12 and 18. The survey was conducted by the Corporation for National and Community Service in collaboration with the U.S. Census Bureau and the nonprofit coalition Independent Sector. The survey collected information on teen volunteering habits, experiences with school-based service-learning, and other forms of civic engagement. This report explores the attitudes and behaviors of youth from disadvantaged circumstances toward volunteering and other forms of civic engagement

The Health Benefits of Volunteering: A Review of Recent Research

Over the past two decades we have seen a growing body of research that indicates volunteering provides individual health benefits in addition to social benefits. This research has established a strong relationship between volunteering and health: those who volunteer have lower mortality rates, greater functional ability, and lower rates of depression later in life than those who do not volunteer. Comparisons of the health benefits of volunteering for different age groups have also shown that older volunteers are the most likely to receive greater benefits from volunteering, whether because they are more likely to face higher incidence of illness or because volunteering provides them with physical and social activity and a sense of purpose at a time when their social roles are changing. Some of these findings also indicate that volunteers who devote a "considerable" amount of time to volunteer activities (about 100 hours per year) are most likely to exhibit positive health outcomes

Youth Helping America - Educating for Active Citizenship: Service-Learning, School-Based Service and Youth Civic Engagement

This brief is the second in the Youth Helping America Series, a series of reports based on data from the Youth Volunteering and Civic Engagement Survey, a national survey of 3,178 American youth between the ages of 12 and 18 that was conducted by the Corporation for National and Community Service in 2005 in collaboration with the U.S. Census Bureau and the nonprofit coalition Independent Sector. The survey collected information on teen volunteering habits, experiences with school-based service-learning, and other forms of civic engagement. While the first brief in the Youth Helping America Series focused on youth volunteering and social institutions, this brief focuses on participation in school-based service — service opportunities made available or required by schools — among middle school and high school aged youth. We pay particular attention to the extent to which youth participate in service-learning courses, which integrate school-based service opportunities into the academic curriculum such as those programs supported by Learn and Serve America

The Arizona State University Percussion/Clarinet Duo Robert Spring, Clarinet J.B. Smith, Percussion

Kemp Recital Hall Sunday Evening January 29, 1995 8:00p

Urokinase‐type plasminogen activator enhances invasion of human T cells (Jurkat) into a fibrin matrix

The receptor for urokinase‐type plasminogen activator (uPA‐R) localizes uPA to the cell surface. The receptor‐bound uPA converts plasminogen to the trypsinlike endopeptidase plasmin. Thus uPA is involved in the initiation of pericellular proteolysis. Pericellular proteolysis is assumed to facilitate the cellular infiltration into surrounding tissue. The uPA‐R has recently been identified as a surface antigen of activated human T lymphocytes. We have characterized the uPA‐R of the human CD4+ T cell line Jurkat by immunological (flow cytometry), biochemical (ligand blotting), and physico‐chemical (Scatchard blotting) methods. The collective data suggest that the human CD4+ T cell line Jurkat expresses a cell surface receptor for uPA similar to that of myelo/monocytes and normal T cells with regard to size, affinity, ligand specificity, and antigenicity. Binding studies using exogenous uPA and subsequent functional assays revealed that receptor‐bound uPA retains its enzymatic activity. Saturation of the Jurkat cell uPA‐R with exogenous uPA facilitated cellular invasion into fibrin matrices in vitro. uPA‐dependent invasion was inhibited in the presence of an anti‐catalytic monoclonal anti‐uPA antibody. We propose that uPA‐R‐bound uPA may facilitate the invasiveness of uPA‐R‐positive T lymphocytes. J. Leukoc. Biol. 56: 110–116; 1994.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142166/1/jlb0110.pd

Cross-Species Differential Plasma Protein Binding of MBX-102/JNJ39659100: A Novel PPAR-γ Agonist

Drug binding to plasma proteins restricts their free and active concentrations, thereby affecting their pharmacokinetic properties. Species differences in plasma protein levels complicate the understanding of interspecies pharmacodynamic and toxicological effects. MBX-102 acid/JNJ39659100 is a novel PPAR-γ agonist in development for the treatment of type 2 diabetes. Studies were performed to evaluate plasma protein binding to MBX-102 acid and evaluate species differences in free drug levels. Equilibrium dialysis studies demonstrated that MBX-102 acid is highly bound (>98%) to human, rat and mouse albumin and that free MBX-102 acid levels are higher in rodent than in human plasma. Interspecies differences in free drug levels were further studied using PPAR-γ transactivation assays and a newly developed PPAR-γ corepressor displacement (biochemical) assay. PPAR-γ transactivation and corepressor displacement by MBX-102 acid was higher in rat and mouse serum than human serum. These results confirm the relevance of interspecies differences in free MBX-102 acid levels

Exome sequencing identifies nonsegregating nonsense ATM and PALB2 variants in familial pancreatic cancer.

We sequenced 11 germline exomes from five families with familial pancreatic cancer (FPC). One proband had a germline nonsense variant in ATM with somatic loss of the variant allele. Another proband had a nonsense variant in PALB2 with somatic loss of the variant allele. Both variants were absent in a relative with FPC. These findings question the causal mechanisms of ATM and PALB2 in these families and highlight challenges in identifying the causes of familial cancer syndromes using exome sequencing

Clark University LGBTQ+ History

Robert Deam Tobin, editor in chiefToni Armstrong and Arai Long, co-editorsAdditional research provided by Griffin Minigello and the students of: Sexuality and Textuality , Spring 2018 Sexuality and Human Rights , Fall 2018 Sexuality and Textuality , Spring 2019 A collaborative research-based catalog by Robert Tobin and his students. This work reports on and narrativizes Clark University\u27s LGBTQ+ history beginning with the Clark Gay Alliance in the mid 1970s, one of the earliest gay student organizations in the country. The vast majority of research for this work comes from materials in Goddard Library\u27s Archives and Special Collections