Conventional Versus Nuclear Power for CVA-67: A Study of Defense Management

In recent years Robert McNamara and the revolutionary methods he brought with him to DOD have been the focus of considerable dissatisfaction voiced by military men as well as civilian critics of the Defense Establishment

Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination

How polycomb group proteins repress gene expression in vivo is not known. While histone-modifying activities of the polycomb repressive complexes (PRCs) have been studied extensively, in vitro data have suggested a direct activity of the PRC1 complex in compacting chromatin. Here, we investigate higher-order chromatin compaction of polycomb targets in vivo. We show that PRCs are required to maintain a compact chromatin state at Hox loci in embryonic stem cells (ESCs). There is specific decompaction in the absence of PRC2 or PRC1. This is due to a PRC1-like complex, since decompaction occurs in Ring1B null cells that still have PRC2-mediated H3K27 methylation. Moreover, we show that the ability of Ring1B to restore a compact chromatin state and to repress Hox gene expression is not dependent on its histone ubiquitination activity. We suggest that Ring1B-mediated chromatin compaction acts to directly limit transcription in vivo

Developmental Change: An Annotated Bibliography

Developmental change and the related problems of modernization have attracted the attention of scholars in many disciplines. In this bibliography—derived and expanded from an earlier compilation by Mr. Spitz and Edward Weidner—the author orders and annotates nearly 2,500 articles appearing between 1945 and 1969 in 234 journals from 25 countries. Organized by subject and indexed by both author and journal, the citations include studies of social problems, economic factors, political questions, public administration, and international cooperation and assistance. Special emphasis has been given to new and little-known sources. In addition, a selected bibliography of monographs and book-length studies dealing with the modernization of underdeveloped countries and areas is included in the volume. Allan A. Spitz is associate professor of political science at the University of Wisconsin at Janesville.https://uknowledge.uky.edu/upk_politics_and_social_change/1002/thumbnail.jp

The T2K experiment

The T2K experiment is a long baseline neutrino oscillation experiment. Its main goal is to measure the last unknown lepton sector mixing angle θ13 by observing νe appearance in a νμ beam. It also aims to make a precision measurement of the known oscillation parameters, and sin22θ23, via νμ disappearance studies. Other goals of the experiment include various neutrino cross-section measurements and sterile neutrino searches. The experiment uses an intense proton beam generated by the J-PARC accelerator in Tokai, Japan, and is composed of a neutrino beamline, a near detector complex (ND280), and a far detector (Super-Kamiokande) located 295 km away from J-PARC. This paper provides a comprehensive review of the instrumentation aspect of the T2K experiment and a summary of the vital information for each subsystem