217 research outputs found
Identity and Oppression: Differential Responses to an In-Between Status
Oppression operates at various levels, with varying degrees of negativity, and groups respond in markedly different ways. In this paper, the in-between status of the colored South African group is used to illustrate issues of identity and oppression under the Apartheid systemâand differing ways in which oppression was experienced and used. The colored group had many social advantages over Blacks, but were also used to oppress that group. Habituation, accommodation, and relative advantage were identified as dynamics within the broader context of power and privilege that contributed to cultural and psychological marginality and status ambivalence of the coloreds. These processes must be understood within the historical, social, and political context of the community. What is evident from the data is that groups and individuals can take up various positions along a continuum of oppressorâoppressed, depending upon the contexts, time, and social and legal relationships involved in their interactions
Culture and Community Interactions: Essentials for understanding in a globalised world
"Introduction to the issue
Mass Photometry of Membrane Proteins
Integral membrane proteins (IMPs) are biologically highly significant but challenging to study because they require maintaining a cellular lipid-like environment. Here, we explore the application of mass photometry (MP) to IMPs and membrane-mimetic systems at the single-particle level. We apply MP to amphipathic vehicles, such as detergents and amphipols, as well as to lipid and native nanodiscs, characterizing the particle size, sample purity, and heterogeneity. Using methods established for cryogenic electron microscopy, we eliminate detergent background, enabling high-resolution studies of membrane-protein structure and interactions. We find evidence that, when extracted from native membranes using native styrene-maleic acid nanodiscs, the potassium channel KcsA is present as a dimer of tetramersâin contrast to results obtained using detergent purification. Finally, using lipid nanodiscs, we show that MP can help distinguish between functional and non-functional nanodisc assemblies, as well as determine the critical factors for lipid nanodisc formation
Validation study of a web-based assessment of functional recovery after radical prostatectomy
<p>Abstract</p> <p>Background</p> <p>Good clinical care of prostate cancer patients after radical prostatectomy depends on careful assessment of post-operative morbidities, yet physicians do not always judge patient symptoms accurately. Logistical problems associated with using paper questionnaire limit their use in the clinic. We have implemented a web-interface ("STAR") for patient-reported outcomes after radical prostatectomy.</p> <p>Methods</p> <p>We analyzed data on the first 9 months of clinical implementation to evaluate the validity of the STAR questionnaire to assess functional outcomes following radical prostatectomy. We assessed response rate, internal consistency within domains, and the association between survey responses and known predictors of sexual and urinary function, including age, time from surgery, nerve sparing status and co-morbidities.</p> <p>Results</p> <p>Of 1581 men sent an invitation to complete the instrument online, 1235 responded for a response rate of 78%. Cronbach's alpha was 0.84, 0.86 and 0.97 for bowel, urinary and sexual function respectively. All known predictors of sexual and urinary function were significantly associated with survey responses in the hypothesized direction.</p> <p>Conclusions</p> <p>We have found that web-based assessment of functional recovery after radical prostatectomy is practical and feasible. The instrument demonstrated excellent psychometric properties, suggested that validity is maintained when questions are transferred from paper to electronic format and when patients give responses that they know will be seen by their doctor and added to their clinic record. As such, our system allows ready implementation of patient-reported outcomes into routine clinical practice.</p
Continued availability and sale of pangolins in a major urban bushmeat market in Cameroon despite national bans and the COVID-19 outbreak
First paragraph: Bushmeat (or âwild meatâ, defined as the meat of wild animals) is a major source of protein for rural people across sub-Saharan Africa (Ingram et al., 2021), yet some species suffer unsustainable levels of exploitation often to meet the demands of increasing urban populations (Coad et al., 2019; Wilkie et al., 2016). As in the rest of Central Africa, Cameroon has a long history of bushmeat consumption and trade (Bahuchet & Ioveva, 1999; Randolph, 2016). Pangolins (Family: Manidae) have been one of the many groups of species exploited as they are highly valued for food and, in some countries, used as traditional remedies (Soewu et al., 2020). Pangolin meat is favoured for its taste and it remains commonly offered for sale in Cameroonian markets and restaurants (Ingram et al., 2018; Nguyen et al., 2021). Furthermore, Cameroon has become one of the major export countries for the illegal trade in pangolin scales from Africa to Asia (Ingram et al., 2019a), to supply the market for Asian traditional medicines, for example in traditional Chinese medicine (Wang et al., 2020). All African pangolin species are now considered to have declining population trends (Ingram et al., 2019b; Nixon et al., 2019; Pietersen et al., 2019a, 2019b)
Open Problems on Central Simple Algebras
We provide a survey of past research and a list of open problems regarding
central simple algebras and the Brauer group over a field, intended both for
experts and for beginners.Comment: v2 has some small revisions to the text. Some items are re-numbered,
compared to v
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