Lean Implementation Difference Between Lean Maturity, Psychological Well-being, and Employee Engagement of Nurses in a Hospital Setting

This quantitative study examined the differences of Lean implementation in three settings; (a hospital in a health system where Lean is implemented throughout the system, a hospital that has implemented Lean in a health system that has not implemented Lean, a hospital that has not implemented Lean in a health system that has not implemented Lean) between LM, PWB, and EE among nurses in a hospital setting. The theoretical construct of the job demands-resources model is used to base the study. Three survey instruments (Psychological Well-Being Scale, Utrecht Work Engagement Scale, Lean Healthcare Implementation Self-Assessment Instrument) were self-administered by registered nurses over 18 after consent. A Kruskal-Wallis test was conducted based on parametric assumptions violations. Results demonstrate a Lean implementation alone may not be enough of a resource to influence EE and PWB, however, does influence LM within the JDR construct. Focus on additional resources while doing a Lean implementation may enhance the EE and PWB of nurses within the hospital setting. The benefits of this study will provide healthcare leaders with an empirical understanding of Lean as a continuous improvement tool and how it impacts nursing emotions and behaviors. Additional benefits include assisting healthcare organizations, consultants, and academicians with tactics that could demonstrate continuous improvements and cultural improvements through an industrial-organizational psychology lens

ANALYSIS OF CHANGING METHODS OF VERTICAL COORDINATION IN THE PORK INDUSTRY

This study examines the motivation behind contracts and vertical integration in the pork industry, and simulates the effects of potential improvements in coordination. Incentives related to lowering costs of measuring and sorting hogs, and protecting against opportunistic behavior associated with specific assets, can result in hog quality improvements. A framework for simulating the effects of increased coordination through contracts and vertical integration was developed and used to evaluate potential improvements in leanness. Although simulations suggest only modest changes in pork prices and supplies, gains in consumers' surplus could be substantial for larger demand shifts due to quality improvements.Contracts, Hogs, Lean pork, Simulation model, Vertical coordination, Vertical integration, Industrial Organization, Livestock Production/Industries,

Strategic Alliances in U.S. Branded Beef Programs

In this paper, we combine concepts from organizational economics to examine supply chain alliances formed to market branded beef products. To illustrate application of the framework, we examine three different types of alliances. We conclude that measuring costs associated with quality attributes have an important role in alliance structure.Agribusiness,

Effects of Leaf Diversity on Tannin Concentration and Water Quality

The abstract for this presentation can be downloaded by clicking on the blue download button

Specific targeting of cytosine methylation to DNA sequences in vivo

Development of methods that will allow exogenous imposition of inheritable gene-specific methylation patterns has potential application in both therapeutics and in basic research. An ongoing approach is the use of targeted DNA methyltransferases, which consist of a fusion between gene-targeted zinc-finger proteins and prokaryotic DNA cytosine methyltransferases. These enzymes however have so far demonstrated significant and unacceptable levels of non-targeted methylation. We now report the development of second-generation targeted methyltransferase enzymes comprising enhanced zinc-finger arrays coupled to methyltransferase mutants that are functionally dominated by their zinc-finger component. Both in vitro plasmid methylation studies and a novel bacterial assay reveal a high degree of target-specific methylation by these enzymes. Furthermore, we demonstrate for the first time transient expression of targeted cytosine methyltransferase in mammalian cells resulting in the specific methylation of a chromosomal locus. Importantly, the resultant methylation pattern is inherited through successive cell divisions

Use of altered-specificity binding Oct-4 suggests an absence of pluripotent cell-specific cofactor usage

Oct-4 is a POU domain transcription factor that is critical for maintaining pluripotency and for stem cell renewal. Previous studies suggest that transcription regulation by Oct-4 at particular enhancers requires the input of a postulated E1A-like cofactor that is specific to pluripotent cells. However, such studies have been limited to the use of enhancer elements that bind other POU-protein family members in addition to Oct-4, thus preventing a ‘clean’ assessment of any Oct-4:cofactor relationships. Other attempts to study Oct-4 functionality in a more ‘stand-alone’ situation target Oct-4 transactivation domains to DNA using heterologous binding domains, a methodology which is known to generate artificial data. To circumvent these issues, an altered-specificity binding Oct-4 (Oct-4RR) and accompanying binding site, which binds Oct-4RR only, were generated. This strategy has previously been shown to maintain Oct-1:cofactor interactions that are highly binding-site and protein/binding conformation specific. This system therefore allows a stand-alone study of Oct-4 function in pluripotent versus differentiated cells, without interference from endogenous POU factors and with minimal deviation from bound wild-type protein characteristics. Subsequently, it was demonstrated that Oct-4RR and the highly transactive regions of its N-terminus determined here, and its C-terminus, have the same transactivation profile in pluripotent and differentiated cells, thus providing strong evidence against the existence of such a pluripotent cell-specific Oct-4 cofactor

No. 3, The Hooper Site (40DV234), A Mississippian Village in Davidson County, Tennessee

https://digitalcommons.memphis.edu/govpubs-tn-dept-environment-conservation-archaeology-miscellaneous/1002/thumbnail.jp

Simulated annealing and greedy search for multi-objective optimisation

Copyright © 2009 University of ExeterSimulated annealing generalises greedy or elitist search methods by permitting states which are not an improvement over previous solutions, and for single-objective problems these exploratory moves permit escape from local minima. We examine two classes of multi-objective simulated annealing algorithm: those in which a single solution comprises the state and those in which a set of mutually non-dominating solutions form the state. We compare ways of determining the `energy' of the state in simulated annealing, including the dominated volume and we relate the greedy versions of these annealers (zero computational temperature) to well-established multi-objective optimisation algorithms. Empirical tests on the DTLZ test problems show that (a) a single solution state is often more efficient than a set-based state; and (b) that exploratory algorithms are out-performed by their greedy counterparts. These results lead to an examination of the role of local fronts. Problems for which the Pareto front cannot be located via a sequence of infinitesimal perturbations are defined to be noninfinitesimally greedy searchable. We present examples of non-infinitesimally greedy searchable test problems, which are nonetheless searchable using finite perturbations, but which may be adjusted to be arbitrarily hard even with large finite perturbations.Department of Computer Science, University of Exete