3,752 research outputs found

    The Williams Scale of Attitude toward Paganism: development and application among British Pagans

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    This article builds on the tradition of attitudinal measures of religiosity established by Leslie Francis and colleagues with the Francis Scale of Attitude toward Christianity (and reflected in the Sahin-Francis Scale of Attitude toward Islam, the Katz-Francis Scale of Attitude toward Judaism, and the Santosh-Francis Scale of Attitude toward Hinduism) by introducing a new measure to assess the attitudinal disposition of Pagans. A battery of items was completed by 75 members of a Pagan Summer Camp. These items were reduced to produce a 21-item scale that measured aspects of Paganism concerned with: the God/Goddess, worshipping, prayer, and coven. The scale recorded an alpha coefficient of 0.93. Construct validity of the Williams Scale of Attitude toward Paganism was demonstrated by the clear association with measures of participation in private rituals

    Transcriptional regulation of bacterial virulence gene expression by molecular oxygen and nitric oxide

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    © Jeffrey Green, Matthew D Rolfe, and Laura J Smith. Molecular oxygen (O2) and nitric oxide (NO) are diatomic gases that play major roles in infection. The host innate immune system generates reactive oxygen species and NO as bacteriocidal agents and both require O2 for their production. Furthermore, the ability to adapt to changes in O2 availability is crucial for many bacterial pathogens, as many niches within a host are hypoxic. Pathogenic bacteria have evolved transcriptional regulatory systems that perceive these gases and respond by reprogramming gene expression. Direct sensors possess iron-containing co-factors (iron-sulfur clusters, mononuclear iron, heme) or reactive cysteine thiols that react with O2 and/or NO. Indirect sensors perceive the physiological effects of O2 starvation. Thus, O2 and NO act as environmental cues that trigger the coordinated expression of virulence genes and metabolic adaptations necessary for survival within a host. Here, the mechanisms of signal perception by key O2and NO-responsive bacterial transcription factors and the effects on virulence gene expression are reviewed, followed by consideration of these aspects of gene regulation in two major pathogens, Staphylococcus aureus and Mycobacterium tuberculosis

    Childhood IQ and social factors on smoking behaviour, lung function and smoking-related outcomes in adulthood: linking the Scottish Mental Survey 1932 and the Midspan studies

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    OBJECTIVE: To investigate the associations of childhood IQ and adult social factors, and smoking behaviour, lung function (forced expiratory volume in one second; FEV(1)), and smoking-related outcomes in adulthood. DESIGN: Retrospective cohort study. METHOD: Participants were from the Midspan prospective studies conducted on Scottish adults in the 1970s. The sample consisted of 938 Midspan participants born in 1921 who were successfully matched with their cognitive ability test results on the Scottish Mental Survey 1932. RESULTS: Structural equation modelling showed that age 11 IQ was not directly associated with smoking consumption, but that IQ and adult social class had indirect effects on smoking consumption via deprivation category. The influence of IQ on FEV(1) was partly indirect via social class. Gender influenced smoking consumption and also IQ and social class. There was a 21% higher risk of having a smoking-related hospital admission, cancer, or death during 25 years of follow-up for each standard deviation disadvantage in IQ. Adjustment for adult social class, deprivation category, and smoking reduced the association to 10%. CONCLUSION: Childhood IQ was associated with social factors which influenced lung function in adulthood, but was not associated directly with smoking consumption. In future studies, it is important to consider other pathways which may account for variance in the link between childhood IQ and health in later life

    Final Project Report: Wine Suitcase

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    The Wine Suitcase Project was proposed by Dr. Becker to address the problem of a lack of safe and secure transportation of wine during worldwide travel. Currently, there are some solutions, like wine bottle diapers (a special bag to put a wine bottle in and catch the liquid if the bottle breaks) and an expensive wine suitcase, but a protective, insulated and cost-effective wine travel suitcase would be of great help to the wine community. This past year, our team has worked to design and produce said suitcase. The major objectives of this design are that the suitcase has to keep the bottles below the critical temperature of 70°F and safe from breaking during travel and baggage handling. Specifically, the suitcase should be able to pass the International Safe Transit Association’s (ISTA) Test Procedure 2A for Packaged-Products 150 pounds or less and keep the wine below a temperature of 70 °F for up to 36 hours [1]. The bottles should be placed in the bag at a maximum of 65 °F initially. In order for the user to know if his/her wine has been above the 70 °F mark, the design should also include a notification system or temperature tracker. Finally, the suitcase should hold up to 12 bottles of 750 mL wine and come in at a total cost of less than $350 to be competitive against current suitcase designs. The suitcase also needs to be able to hold at least one case of wine (12 bottles) of various sizes. According to these objectives and requirements, a wine suitcase was designed and fabricated using a hard-shell suitcase, foam, insulation and a temperature sensor. Specifically, the hard-shell suitcase and the foam padding satisfied the safety requirement for the bottles and for the temperature stability requirement, the insulation was added as a layer between the foam and suitcase shell. Additionally, in order to communicate to the user what the temperature of the wine is inside the suitcase, the team added a handheld sensor device with Bluetooth capabilities. After fabrication, 7 tests were performed to evaluate the success of the design against the requirements: bottle physical protection test, bottle quantity test, bottle thermal protection test, weight of suitcase test, size of suitcase test, ThermoplusTM temperature sensor test and a heat transfer simulation test. The team was unable to perform the thermal protection test due to the displacement from San Antonio from COVID-19. Each of the other 6 tests were performed and resulted in a success and satisfied their appropriate requirement. The heat transfer simulation test was added after the displacement from COVID-19 to offset the inability to perform the thermal test in person. The thermal simulation test was run to focus on the most critical 15-minute time-frame of the travel journey where the suitcase may be held in direct sunlight. At all other times, the suitcase will be in the cargo hold or inside the air-conditioned airport. While the simulation is not the same as an in-person test, we can still use it as a good measure of the thermal protection capabilities of our design and were satisfied with the passing results. Overall, once the temperature sensor has been installed, we assert that the Wine Suitcase that was fabricated before displacement will be a fully functioning device that can safely transport wine due to the successes of our testing

    Companion planting to attract pollinators increases the yield and quality of strawberry fruit in gardens and allotments

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    1. Global pollinator declines have led to concern that crop yields might fall as a result of a pollination deficit. Companion planting is a traditional practice thought to increase yield of insect pollinated crops by planting a co-flowering species next to the crop. 2. Using a combination of conventional researcher-led experiments and observational citizen scientist data, we tested the effectiveness of bee-friendly borage (Borago officinalis) as a companion plant to strawberry (Fragaria x ananassa). Insect visitors to the ‘Test’ (strawberry + borage) versus ‘Control’ (strawberry only) plants were observed, and strawberry fruit collected. Strawberries collected during the researcher-led experiment were also subject to fruit measurements and assessments of market quality. 3. Companion plants were found to significantly increase both yield and market quality of strawberries, suggesting an increase in insect pollination per plant. Test strawberries companion planted with borage produced an average of 35% more fruits, and 32% increased yield by weight. Test strawberry plants produced significantly more fruit of higher aesthetic quality when assessed by Marketing Standards for Strawberries. 4. Although there was no significant difference in the overall insect visits, when broken down by broad insect group there were significantly more flies visiting the test strawberries than controls. 5. These results could have implications for both gardeners and commercial growers. As consumers prefer a cosmetically perfect fruit, the production of fruit with increased aesthetics aids food waste reduction
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