Short-term outcome after total hip arthroplasty using dual-mobility cup: report from Lithuanian Arthroplasty Register

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesPURPOSE: The purpose of the study was to investigate how the use of dual-mobility cups (DMCs) affected the risk of revision due to dislocation as well as overall risk of revision compared with a conventional total hip arthroplasty (THA) system in the short term. METHODS: A total of 12,657 primary THAs were registered from the start of 2011 to the end of 2014. 620 THAs were with DMCs. For comparison, we included all registered THAs with Exeter cup and a cemented Exeter stem combined with 28-mm femoral head. Patients were followed up with respect to revision and/or death until 1 January 2016. For survival analysis, we used revision as an endpoint. Cox proportional hazards models were used to analyse the influence of various covariates (age, gender, surgical approach, THA model and pre-operative diagnosis). RESULTS: Of the 620 dual-mobility THAs and 2170 Exeter THAs, 100 had been revised. The overall unadjusted cumulative revision rate (CRR) for any reason of revision at five years after surgery was 3.9% in the dual-mobility group and 5.2% in the Exeter group. Cox regression analysis, adjusting for age, gender, THA type, surgical approach and pre-operative diagnosis, showed that the risk of revision was less in patients operated with DMCs and in patients having their operation for osteoarthritis. CONCLUSION: The DM implant had a lower short-term complication rate than a conventional well defined THA. Low dislocation rate suggests that it is a good choice for high risk patients

Estimation of expected cargo oil outflow from tanker involved in casualty

Modified version of simplified probabilistic methodology, designed for estimation of expected cargo oil outflow from tanker involved in casualty, is proposed. Suggested modified methodology can be used in the circumstances, when only very limited initial input data about the incident and tanker design is available. When applied in certain sea region (for example in Lithuanian sector of the Baltic Sea area), proposed methodology can be used in extremely short time spans, ‐ estimation procedure requires several times less time than standard IMO methodologies, and gives quite insignificant errors of estimated oil outflow. First Published Online: 27 Oct 201

Femoral neck fractures in Lithuania and Sweden. The differences in care and outcome

Hip fractures constitute a serious and common health problem from both individual and public health perspectives. Unified data collection and comparison between countries is recognised as an effective tool for care improvements. However, the variation in patients' demography, treatment methods and other local cultural aspects in different countries should be considered. The aim of our study was to compare femoral neck fracture patients treated in Kaunas and Lund, concerning functional outcome and quality of life. We investigated 99 patients treated by arthroplasty in Kaunas Clinics and 117 patients in Lund University Hospital. Patients were investigated according to the National Swedish Hip Fracture Register model and were followed up for a period of four months after the injury. The patient's place of residence, mobility, complaints of pain and additional hospital stay were recorded. The EQ-5D questionnaire was used to evaluate quality of life. Patients in Kaunas were significantly younger, had lower ASA grade and were more mobile before trauma and at four moths follow-up. However, when comparing quality of life at four months follow-up between the institutions, Lund patients reported significantly better self care, felt less pain and discomfort, and had less symptoms of anxiety and depression. The difference observed in quality of life rating between institutions might be related to local cultures of the countries and should be considered when comparing the data

The DUSP domain of pseudophosphatase MK-STYX interacts with G3BP1 to decrease stress granules

Mitogen activated protein kinase phosphoserine/threonine/tyrosine-binding protein (MK-STYX) is a dual specificity (DUSP) member of the protein tyrosine phosphatase family. It is a pseudophosphatase, which lacks the essential amino acids histidine and cysteine in the catalytic active signature motif (HC

VANDENS – DUJŲ ŠILUMOS MAINAI GAZ-LIFTO TIPO SKRUBERYJE

In order to reduce sulphur oxide emissions from ships the SOX emission regulations in emission control areas shall be strengthenedand allow only 0,1% of sulphur in marine fuels since 2015. High price of this type of fuel forces ship owners to search for alternativemeans of reducing SOx emissions. Most rational measure is to use scrubber technology. Main type of scrubber that has been widelyanalysed is “shower „ type scrubber. How ever even with widely performed research of these scrubbers they still have somedrawbacks that are of most concern for the owners of small ships. Solution – gaz-lift type scrubbers. In order to improve and adaptgaz-lift type scrubber technology for cleaning of exhaust gases a thorough research has to be performed. Important part of this researchis heat exchange between gas and water in gaz-lift type scrubber. This is done with CFD software – Flow3D. The Simulationresults showed that the temperature of exhaust gases passing the scrubber dropped to around 300-350 k. this results matches theexperimental data, confirms the adequacy of calculation and provides basis for the further use of these models in gaz-lift scrubberresearch.KEY WORDS: GAZ-LIFT, SCRUBBER, SOX, EXHAUST GAS CLEANIN

Calcium Sulphate/Hydroxyapatite Carrier for Bone Formation in the Femoral Neck of Osteoporotic Rats

Final publication is available from Mary Ann Liebert, Inc., publishers https://www.liebertpub.com/doi/pdf/10.1089/ten.tea.2018.0075The authors would like to thank the Swedish Research Council (VR, grant no. 2015-06717), VINNOVA, the Swedish Agency for Innovation Systems (grant no. 2017-00269), and Department of Biotechnology, Government of India (BT/IN/ Sweden/08/AK/2017-18), for providing for the funding to conduct this stud

Turbulence modelling and role of compressibility on oil spilling from a damaged double hull tank

The viscosity plays an important role, and a multiphase solver is necessary to numerically simulate the oil spilling from a damaged double hull tank (DHT). However, it is uncertain whether turbulence modelling is necessary, which turbulence model is suitable; and what the role of compressibility of the fluids is. This paper presents experimental and numerical investigations to address these issues for various cases representing different scenarios of the oil spilling, including grounding and collision. In the numerical investigations, various approaches to model the turbulence, including the large eddy simulation (LES), direct numerical simulation and the Reynolds average Navier-Stokes equation (RANS) with different turbulence models, are employed. Based on the investigations, it is suggested that the effective Reynolds numbers corresponding to both oil outflow and water inflow shall be considered when classifying the significance of the turbulence and selecting the appropriate turbulence models. This is confirmed by new lab tests considering the axial offset between the internal and the external holes on two hulls of the DHT. The investigations conclude for numerically simulating oil spilling from a damaged DHT that when the effective Re is smaller the RANS approaches should not be used and LES modelling should be employed; while when the effective Reynolds numbers is large, the RANS models may be used as they can give similar results to LES in terms of the height of the mixture in the ballast tank and discharge but costing much less CPU time. The investigation on the role of the compressibility of the fluid reveals that the compressibility of the fluid may be considerable in a small temporal-spatial scale but plays an insignificant role on macroscopic process of the oil spilling

Exploring The Role Of Mk-Styx In The Cellular Stress Response

The cell imposes order upon its otherwise chaotic milieu of biomolecules via a series of delineated regions, deemed organelles, by means of encapsulating functionally related proteins within a membrane. Alternatively, however, cells can introduce transient, local increases in order via the inducement of phase separated “membrane-less” organelles. One type of biomolecular condensate is the stress granule (SG), which is a dynamic cytosolic granule formed in response to a myriad of cellular stressors. Recently, MK-STYX has been demonstrated to decrease the number of SGs within HEK293 cells in response to arsenite treatment, indicating a regulatory role within this stress response pathway. Interestingly, a series of seemingly unrelated observations pertaining to MK-STYX have converged on a shared mechanism of regulatory action, centered around SG formation and dispersal. Specifically, MK-STYX is demonstrated in the following work to utilize its DUSP domain to negatively regulate the phosphorylation status of a critical tyrosine residue in G3BP1 (a SG nucleator) as a means of impeding SG formation. Additionally, through low-affinity interactions with β-II spectrin (a cytoskeletal protein), MK-STYX may influence the translocation of these transient condensates to their autophagic destruction. The following work thus highlights the integral role MK-STYX plays in the life cycle of SGs, and further demonstrates the functional utility of a seemingly innocuous pseudophosphatase