330 research outputs found
A series of thirteen original radio programs on music appreciation for students in grades five, six, and seven designed for in-school listening
Thesis (M.S.)--Boston Universit
Improved Standardization of Type II-P Supernovae: Application to an Expanded Sample
In the epoch of precise and accurate cosmology, cross-confirmation using a
variety of cosmographic methods is paramount to circumvent systematic
uncertainties. Owing to progenitor histories and explosion physics differing
from those of Type Ia SNe (SNe Ia), Type II-plateau supernovae (SNe II-P) are
unlikely to be affected by evolution in the same way. Based on a new analysis
of 17 SNe II-P, and on an improved methodology, we find that SNe II-P are good
standardizable candles, almost comparable to SNe Ia. We derive a tight Hubble
diagram with a dispersion of 10% in distance, using the simple correlation
between luminosity and photospheric velocity introduced by Hamuy & Pinto 2002.
We show that the descendent method of Nugent et al. 2006 can be further
simplified and that the correction for dust extinction has low statistical
impact. We find that our SN sample favors, on average, a very steep dust law
with total to selective extinction R_V<2. Such an extinction law has been
recently inferred for many SNe Ia. Our results indicate that a distance
measurement can be obtained with a single spectrum of a SN II-P during the
plateau phase combined with sparse photometric measurements.Comment: ApJ accepted version. Minor change
Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania
Objective: To evaluate the diagnostic performance of two rapid detection tests (RDTs) for HIV 1/2 in plasma and in whole blood samples.
Methods:
More than 15,000 study subjects above the age of two years participated in two rounds of a cohort study to determine the prevalence of HIV. HIV testing was performed using the Determine HIV 1/2 test (Abbott) in the first (2006/2007) and the HIV 1/2 STAT-PAK Dipstick Assay (Chembio) in the second round (2007/2008) of the survey. Positive results were classified into faint and strong bands depending on the visual appearance of the test strip and confirmed by ELISA and Western blot.
Results:
The sensitivity and specificity of the Determine RDT were 100% (95% confidence interval = 86.8 to 100%) and 96.8% (95.9 to 97.6%) in whole blood and 100% (99.7 to 100%) and 97.9% (97.6 to 98.1%) in plasma respectively. Specificity was highly dependent on the tested sample type: when using whole blood, 67.1% of positive results were false positive, as opposed to 17.4% in plasma. Test strips with only faint positive bands were more often false positive than strips showing strong bands and were more common in whole blood than in plasma. Evaluation of the STAT-PAK RDT in plasma during the second year resulted in a sensitivity of 99.7% (99.1 to 99.9%) and a specificity of 99.3% (99.1 to 99.4%) with 6.9% of the positive results being false.
Conclusions:
Our study shows that the Determine HIV 1/2 strip test with its high sensitivity is an excellent tool to screen for HIV infection, but that – at least in our setting – it can not be recommended as a confirmatory test in VCT campaigns where whole blood is used
Supernovae and radio transients in M 82
We present optical and near-infrared (IR) photometry and near-IR spectroscopy
of SN 2004am, the only optically detected supernova (SN) in M 82. These
demonstrate that SN 2004am was a highly reddened type II-P SN similar to the
low luminosity type II-P events such as SNe 1997D and 2005cs. We show that SN
2004am was located coincident with the obscured super star cluster M 82-L, and
from the cluster age infer a progenitor mass of 12 +7/-3 Msun. In addition to
this, we present a high spatial resolution Gemini-N K-band adaptive optics
image of the site of SN 2008iz and a second transient of uncertain nature, both
detected so far only at radio wavelengths. Using image subtraction techniques
together with archival data from the Hubble Space Telescope, we are able to
recover a near-IR transient source co-incident with both objects. We find the
likely extinction towards SN 2008iz to be not more than Av ~ 10. The nature of
the second transient remains elusive and we regard an extremely bright
microquasar in M 82 as the most plausible scenario.Comment: 14 pages, 8 figures, accepted for publication in MNRA
Work-Unit Absenteeism: Effects of Satisfaction, Commitment, Labor Market Conditions, and Time
Prior research is limited in explaining absenteeism at the unit level and over time. We developed and tested a model of unit-level absenteeism using five waves of data collected over six years from 115 work units in a large state agency. Unit-level job satisfaction, organizational commitment, and local unemployment were modeled as time-varying predictors of absenteeism. Shared satisfaction and commitment interacted in predicting absenteeism but were not related to the rate of change in absenteeism over time. Unit-level satisfaction and commitment were more strongly related to absenteeism when units were located in areas with plentiful job alternatives
Enhancement of the Electron Spin Resonance of Single-Walled Carbon Nanotubes by Oxygen Removal
We have observed a nearly fourfold increase in the electron spin resonance
(ESR) signal from an ensemble of single-walled carbon nanotubes (SWCNTs) due to
oxygen desorption. By performing temperature-dependent ESR spectroscopy both
before and after thermal annealing, we found that the ESR in SWCNTs can be
reversibly altered via the molecular oxygen content in the samples. Independent
of the presence of adsorbed oxygen, a Curie-law (spin susceptibility ) is seen from 4 K to 300 K, indicating that the probed spins are
finite-level species. For both the pre-annealed and post-annealed sample
conditions, the ESR linewidth decreased as the temperature was increased, a
phenomenon we identify as motional narrowing. From the temperature dependence
of the linewidth, we extracted an estimate of the intertube hopping frequency;
for both sample conditions, we found this hopping frequency to be 100
GHz. Since the spin hopping frequency changes only slightly when oxygen is
desorbed, we conclude that only the spin susceptibility, not spin transport, is
affected by the presence of physisorbed molecular oxygen in SWCNT ensembles.
Surprisingly, no linewidth change is observed when the amount of oxygen in the
SWCNT sample is altered, contrary to other carbonaceous systems and certain 1D
conducting polymers. We hypothesize that physisorbed molecular oxygen acts as
an acceptor (-type), compensating the donor-like (-type) defects that are
responsible for the ESR signal in bulk SWCNTs.Comment: 14 pages, 7 figure
Horizontal Gene Transfer of a ColV Plasmid Has Resulted in a Dominant Avian Clonal Type of Salmonella enterica Serovar Kentucky
Salmonella enterica continues to be a significant cause of foodborne gastrointestinal illness in humans. A wide variety of Salmonella serovars have been isolated from production birds and from retail poultry meat. Recently, though, S. enterica subsp. enterica serovar Kentucky has emerged as one of the prominent Salmonella serovars isolated from broiler chickens. Recent work suggests that its emergence apparently coincides with its acquisition of a ColV virulence plasmid. In the present study, we examined 902 Salmonella isolates belonging to 59 different serovars for the presence of this plasmid. Of the serovars examined, the ColV plasmid was found only among isolates belonging to the serovars Kentucky (72.9%), Typhimurium (15.0%) and Heidelberg (1.7%). We demonstrated that a single PFGE clonal type of S. Kentucky harbors this plasmid, and acquisition of this plasmid by S. Kentucky significantly increased its ability to colonize the chicken cecum and cause extraintestinal disease. Comparison of the completed sequences of three ColV plasmids from S. Kentucky isolated from different geographical locales, timepoints and sources revealed a nearly identical genetic structure with few single nucleotide changes or insertions/deletions. Overall, it appears that the ColV plasmid was recently acquired by a single clonal type S. Kentucky and confers to its host enhanced colonization and fitness capabilities. Thus, the potential for horizontal gene transfer of virulence and fitness factors to Salmonella from other enteric bacteria exists in poultry, representing a potential human health hazard
Keep them alive! Design and Evaluation of the “Community Fostering Reference Model”
Firms host online communities for commercial purposes, for example in order to integrate customers into ideation for new product development. The success of these firm-hosted online communities depends entirely on the cooperation of a high number of customers that constantly produce valuable knowledge for firms. However, in practice, the majority of successfully implemented communities suffers from stagnation and even a decrease of member activities over time. Literature provides numerous guidelines on how to build and launch these online communities. While these models describe the initial steps of acquiring and activating a community base from scratch very well and explicitly, they neglect continuous member activation and acquistion after a successful launch. Against this background, the authors propose the Community Fostering Reference Model (CoFoRM), which represents a set of general procedures and instruments to continuously foster member activity. In this paper, the authors present the theory-driven design as well as the evaluation of the CoFoRM in a practical use setting. The evaluation results reveal that the CoFoRM represents a valuable instrument in the daily working routine of community managers, since it efficiently helps activating community members especially in the late phases of a community’s LifeCycle
Pathways to health: a framework for health-focused research and practice
Public health research and practice is faced with three problems: 1) a focus on disease instead of health, 2) consideration of risk factor/disease relationships one at a time, and 3) attention to individuals with limited regard for the communities in which they live. We propose a framework for health-focused research and practice. This framework encompasses individual and community pathways to health while incorporating the dynamics of context and overall population vulnerability and resilience. Individual pathways to health may differ, but commonalities will exist. By understanding these commonalities, communities can work to support health-promoting pathways in addition to removing barriers. The perspective afforded by viewing health as a dynamic process instead of as a collection of risk factors and diseases expands the number of approaches to improving health globally. Using this approach, multidisciplinary research teams working with active community participants have the potential to reshape health and intervention sciences
- …