Surface properties of Galilean satellites from bistatic radar experiments

The icy moons of Jupiter were the first to show unusual radar backscatter behavior in Earth-based experiments. Studies of Europa, Ganymede, and Callisto revealed strong echoes and a reversed sense of circular polarization. No explanations were entirely satisfactory because of the difficult constraints imposed by the existing data. The (scalar) bidirectional coherence model predicts an opposition effect, or enhancement in the backscatter direction, resulting from coherent addition of backscatter from identical (but oppositely directed) ray paths. The mode decoupling model yields a similar, vector result in which the observed polarization properties of the backscattered wave can also be obtained. The possibilities were considered for conducting such experiments using the Galileo spacecraft. Both conventional oblique-forward bistatic experiments (to determine basic electrical and physical properties of the surface material on centimeter-meter scales) and near-backscatter experiments (to sample the enhanced backscatter lobe) were considered

Estimating Atmospheric Mass Using Air Density

Since the late 19th century, several investigators have estimated the mass of the atmosphere. Unlike previous studies, which focus on the average pressures on the earth's surface, this analysis uses the density of air above the earth's surface to predict the mass of the atmosphere. Results are consistent with recent pressure-based estimates. They indicate that changes in the latest estimates can be attributed to improved land elevation measurements between 1 km and 3 km. This work also provides estimates of atmospheric mass by layer and mean and median land elevations

A study of microwave downcoverters operating in the K sub u band

A computer program for parametric amplifier design is developed with special emphasis on practical design considerations for microwave integrated circuit degenerate amplifiers. Precision measurement techniques are developed to obtain a more realistic varactor equivalent circuit. The existing theory of a parametric amplifier is modified to include the equivalent circuit, and microwave properties, such as loss characteristics and circuit discontinuities are investigated

Embedded Eigenvalues and the Nonlinear Schrodinger Equation

A common challenge to proving asymptotic stability of solitary waves is understanding the spectrum of the operator associated with the linearized flow. The existence of eigenvalues can inhibit the dispersive estimates key to proving stability. Following the work of Marzuola & Simpson, we prove the absence of embedded eigenvalues for a collection of nonlinear Schrodinger equations, including some one and three dimensional supercritical equations, and the three dimensional cubic-quintic equation. Our results also rule out nonzero eigenvalues within the spectral gap and, in 3D, endpoint resonances. The proof is computer assisted as it depends on the sign of certain inner products which do not readily admit analytic representations. Our source code is available for verification at http://www.math.toronto.edu/simpson/files/spec_prop_asad_simpson_code.zip.Comment: 29 pages, 27 figures: fixed a typo in an equation from the previous version, and added two equations to clarif

The Application of CRISPR Technology to High Content Screening in Primary Neurons

Axon growth is coordinated by multiple interacting proteins that remain incompletely characterized. High content screening (HCS), in which manipulation of candidate genes is combined with rapid image analysis of phenotypic effects, has emerged as a powerful technique to identify key regulators of axon outgrowth. Here we explore the utility of a genome editingapproach referred to as CRISPR (Clustered Regularly Interspersed Palindromic Repeats) for knockout screening in primary neurons. In the CRISPR approach a DNA-cleaving Cas enzyme is guided to genomic target sequences by user-created guide RNA (sgRNA), where it initiates a double-stranded break that ultimately results in frameshift mutation and loss of protein production. Using electroporation of plasmid DNA that co-expresses Cas9enzyme and sgRNA, we first verified the ability of CRISPR targeting to achieve protein-level knockdown in cultured postnatal cortical neurons. Targeted proteins included NeuN (RbFox3) and PTEN, a well-studied regulator of axon growth. Effective knockdown lagged at least four days behind transfection, but targeted proteins were eventually undetectable by immunohistochemistry in \u3e 80% of transfected cells. Consistent with this, anti-PTEN sgRNA produced no changes in neurite outgrowth when assessed three days post-transfection. When week-long cultures were replated, however, PTEN knockdown consistently increased neurite lengths. These CRISPR-mediated PTEN effects were achieved using multi-well transfection and automated phenotypic analysis, indicating the suitability of PTEN as a positive control for future CRISPR-based screening efforts. Combined, these data establish an example of CRISPR-mediated protein knockdown in primary cortical neurons and its compatibility with HCS workflows

Stanford telemetry monitoring experiment on Lunar Explorer 35 Final report

Explorer 35 data analysis including occultation study and antenna pattern interpretation along with electromagnetic property experiment

Scattering properties of Venus' surface

Radar backscatter functions Sigma-(carat)(sub 0)(phi) for incidence angles between 0 less than or equal to phi less than or equal to 4-10 deg were derived from Magellan altimetry radar echoes. The procedure includes constrained solution of a system of simultaneous equations for which the echo-spectrum and echo time profile are inputs. A practical and workable set of constraints was applied; optimization and improved results are expected as the analysis matures. The scattering functions yield information on small-scale surface structures (tens of centimeters to tens of meters) but averaged over hundreds of sq km. RMS surface slopes derived from fits of analytic functions to the Sigma-(carat)(sub 0)(phi) results were converted to map form and show patterns similar to those reported using other techniques. While all three forms are found on Venus, fit residuals imply that an exponential scattering function matches data better than either the Hagfors or Gaussian form in most areas, although the Hagfors function may be a better descriptor at some sites. Limited study of image data indicates that average backscatter cross section, and possibly its slope, can be derived at oblique angles (17 deg less than or equal to phi less than or equal to 45 deg). Offsets of the echo peak in altimetry spectra are surprisingly common and are loosely correlated with Venus topography, but no cause for this phenomenon was identified

Spectral Analysis for Matrix Hamiltonian Operators

In this work, we study the spectral properties of matrix Hamiltonians generated by linearizing the nonlinear Schr\"odinger equation about soliton solutions. By a numerically assisted proof, we show that there are no embedded eigenvalues for the three dimensional cubic equation. Though we focus on a proof of the 3d cubic problem, this work presents a new algorithm for verifying certain spectral properties needed to study soliton stability. Source code for verification of our comptuations, and for further experimentation, are available at http://www.math.toronto.edu/simpson/files/spec_prop_code.tgz.Comment: 57 pages, 22 figures, typos fixe

The HI Chronicles of LITTLE THINGS BCDs II: The Origin of IC 10's HI Structure

In this paper we analyze Very Large Array (VLA) telescope and Green Bank Telescope (GBT) atomic hydrogen (HI) data for the LITTLE THINGS(1) blue compact dwarf galaxy IC 10. The VLA data allow us to study the detailed HI kinematics and morphology of IC 10 at high resolution while the GBT data allow us to search the surrounding area at high sensitivity for tenuous HI. IC 10's HI appears highly disturbed in both the VLA and GBT HI maps with a kinematically distinct northern HI extension, a kinematically distinct southern plume, and several spurs in the VLA data that do not follow the general kinematics of the main disk. We discuss three possible origins of its HI structure and kinematics in detail: a current interaction with a nearby companion, an advanced merger, and accretion of intergalactic medium. We find that IC 10 is most likely an advanced merger or a galaxy undergoing accretion. 1:Local Irregulars That Trace Luminosity Extremes, The HI Nearby Galaxy Survey; https://science.nrao.edu/science/surveys/littlethingsComment: 36 pages, 17 figures, accepted for publication in The Astronomical Journa

The detection and photometric redshift determination of distant galaxies using SIRTF's Infrared Array Camera

We investigate the ability of the Space Infrared Telescope Facility's Infrared Array Camera to detect distant (z ~ 3)galaxies and measure their photometric redshifts. Our analysis shows that changing the original long wavelength filter specifications provides significant improvements in performance in this and other areas.Comment: 28 pages incl 12 figures; to appear in June 1999 PASP. Fig.12 replaced with corrected versio