1,781 research outputs found

    Textiles Recorded: Fashion Reconstructed Through Aztec Codices

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    The historical documentation of the use of textiles during the Aztec empire as tribute offerings and sumptuary laws indicates the elevated role of textiles at the time. Yet, further research is warranted on the artistry of these textiles. This is difficult because the climate of central Mexico is not conducive to preserving fiber materials; fortunately, the rich manuscripts of this region preserve many images of textiles created during the Aztec empire. Early colonial manuscripts, many of which are copies of pre-conquest manuscripts no longer extant, preserve images of textiles from the pre-conquest period. These manuscripts provide invaluable information regarding the regional variations, creation technologies and costume elements for textiles. This paper explores images and texts of two groups of textiles: textiles with diagonal bifurcations, and jaguar related textiles found in the Codex Mendoza, the Matrícula de Tributos, the Codex Magliabechiano and the Florentine Codex. These textile groups provide insights into the naming practices, materials and status given to textiles in central Mexico at the time of the Aztec Empire. Nacazminqui Textiles According to the Florentine Codex, “for the fifth one whom he captured, then he gained great honor 
 Then Moctezuma gave him a long blue labret and a head band with [two] tufts of [eagle] feathers, perchance with silver flint knives [between the eagle feathers], and leather ear plugs, and a bright red, rich, netting cape. And also he was then given a cape of two colors divided diagonally, and a leather cape.” The Nahuatl text identifies this textile as chicoapalnacazminqui. The image accompanying this text depicts a textile diagonally bifurcated, with two solid color blocks. An illustration from the Codex Magliabechiano is nearly identical to the Florentine Codex image, however, the gloss is given in Spanish as the “Mantle of Dead nose.” While the Florentine text describes this textile as a gift to a warrior after capturing five enemies, the ethnographic section of the Codex Mendoza (folio 64r) differs slightly from this description by illustrating a warrior who has captured four enemies alongside an image of a textile. The gloss does not identify the textile’s design as nacazminqui, rather it merely states that “This warrior [receives] the style of warrior costume he is wearing and this square manta of two stripes of black and orange with its border in honor of having captured four enemies in battle

    Using a cognitive architecture to examine what develops

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    Different theories of development propose alternative mechanisms by which development occurs. Cognitive architectures can be used to examine the influence of each proposed mechanism of development while keeping all other mechanisms constant. An ACT-R computational model that matched adult behavior in solving a 21-block pyramid puzzle was created. The model was modified in three ways that corresponded to mechanisms of development proposed by developmental theories. The results showed that all the modifications (two of capacity and one of strategy choice) could approximate the behavior of 7-year-old children on the task. The strategy-choice modification provided the closest match on the two central measures of task behavior (time taken per layer, r = .99, and construction attempts per layer, r = .73). Modifying cognitive architectures is a fruitful way to compare and test potential developmental mechanisms, and can therefore help in specifying “what develops.

    Substance P induces localization of MIF/α1-inhibitor-3 complexes to umbrella cells via paracellular transit through the urothelium in the rat bladder

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    BACKGROUND: Macrophage migration inhibitory factor (MIF) is released into the intraluminal fluid during bladder inflammation in the rat complexed to α1-inhibitor-3 (A1-I3; a rodent proteinase inhibitor in the α-macroglobulin family). The location of A1-I3 in the bladder had not been investigated. Therefore, we examined the location of A1-I3 and MIF/A1-I3 complexes in the bladder and changes due to experimental inflammation. METHODS: Anesthetized male rats had bladders removed with no treatment (intact) or were injected with Substance P (SP; s.c.; saline vehicle). After one hour intraluminal fluid was removed, bladder was excised and MIF and A1-I3 levels were determined using ELISA and/or western-blotting. MIF co-immunoprecipitation determined MIF/A1-I3 complexes in the bladder. Bladder sections were immunostained for A1-I3 and MIF/A1-I3. RESULTS: A1-I3 immunostaining was observed in interstitial spaces throughout the bladder (including submucosa) but not urothelium in intact and saline-treated rats. RT-PCR showed that the bladder does not synthesize A1-I3, therefore, A1-I3 in the interstitial space of the bladder must be plasma derived. In SP-treated rats, A1-I3 in the bladder increased and A1-I3 was observed traversing through the urothelium. Umbrella cells that do not show MIF and/or A1-I3 immunostaining in intact or saline-treated rats, showed co-localization of MIF and A1-I3 after SP-treatment. Western blotting demonstrated that in the bladder MIF formed non-covalent interactions and also binds covalently to A1-I3 to form high molecular weight MIF/A1-I3 complexes (170, 130 and 75-kDa, respectively, verified by co-immunoprecipitation). SP-induced inflammation selectively reduced 170-kDa MIF/A1-I3 in the bladder while increasing 170 and 130-kDa MIF/A1-I3 in the intraluminal fluid. CONCLUSION: A1-I3 and MIF/A1-I3 complexes are resident in bladder interstitium. During SP-induced inflammation, MIF/A1-I3 complexes are released from the bladder into the lumen. Binding of MIF/A1-I3 complexes to urothelial cells during inflammation suggests these complexes participate in the inflammatory reaction through activation of receptors for MIF and/or for A1-I3

    Resident Decision Making: Opioids in the Outpatient Setting

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    Pain represents the chief complaint for nearly half of all emergency department (ED) and outpatient clinic visits in the United States, and as much as it pains the first author to admit it (being a resident physician himself), residents are the frontline clinicians who encounter these patients. Despite available resources, residents often are ill-prepared to manage these patients, particularly in regard to the use of opioid analgesics. Compared to other providers, residents are more likely to overtreat abusers of opioid analgesics and refill opioid prescriptions more quickly. The reasons for this behavior deserve further scrutiny. In this Perspectives article, we ask why residents may be more likely to prescribe opioids for pain, and we provide recommendations for educational interventions to address this

    Assigning Triaged Patients to Treatment Rooms in a Hospital Emergency Department

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    The assigning of new arrivals at a hospital emergency department to treatment rooms was examined. New patients are summarily triaged and assigned to a treatment room based on severity of their symptoms, the grade of a treatment room, and an exponential benefit curve that encourages the solver to schedule the most severe cases early. SAS’s OPTMODEL modeling language was employed to build the model and SAS’s MILP solver was used to perform the scheduling. Up to thirty patients were optimally assigned to depict the example of a large emergency department

    Prospectus, May 2, 2001

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    https://spark.parkland.edu/prospectus_2001/1015/thumbnail.jp

    In vitro expansion of U87-MG human glioblastoma cells under hypoxic conditions affects glucose metabolism and subsequent in vivo growth

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    Hypoxia is a characteristic feature of solid tumors leading to the over expression of hypoxia-inducible factor (HIF)-1α protein and therefore to a specific cellular behavior. However, even though the oxygen tension in tumors is low (<5 %), most of the cell lines used in cancer studies are grown under 21 % oxygen tension. This work focuses on the impact of oxygen conditions during in vitro cell culture on glucose metabolism using 1-13C-glucose. Growing U87-MG glioma cells under hypoxic conditions leads to a two- to threefold reduction of labeled glutamine and an accumulation of fructose. However, under both hypoxic and normoxic conditions, glucose is used for de novo synthesis of pyrimidine since the 13C label is found both in the uracil and ribose moieties. Labeling of the ribose ring demonstrates that U87-MG glioma cells use the reversible branch of the non-oxidative pentose phosphate pathway. Interestingly, stereotactic implantation of U87-MG cells grown under normoxia or mild hypoxia within the striatum of nude mice led to differential growth; the cells grown under hypoxia retaining an imprint of the oxygen adaptation as their development is then slowed down

    The Wide Brown Dwarf Binary Oph 1622-2405 and Discovery of A Wide, Low Mass Binary in Ophiuchus (Oph 1623-2402): A New Class of Young Evaporating Wide Binaries?

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    We imaged five objects near the star forming clouds of Ophiuchus with the Keck Laser Guide Star AO system. We resolved Allers et al. (2006)'s #11 (Oph 16222-2405) and #16 (Oph 16233-2402) into binary systems. The #11 object is resolved into a 243 AU binary, the widest known for a very low mass (VLM) binary. The binary nature of #11 was discovered first by Allers (2005) and independently here during which we obtained the first spatially resolved R~2000 near-infrared (J & K) spectra, mid-IR photometry, and orbital motion estimates. We estimate for 11A and 11B gravities (log(g)>3.75), ages (5+/-2 Myr), luminosities (log(L/Lsun)=-2.77+/-0.10 and -2.96+/-0.10), and temperatures (Teff=2375+/-175 and 2175+/-175 K). We find self-consistent DUSTY evolutionary model (Chabrier et al. 2000) masses of 17+4-5 MJup and 14+6-5 MJup, for 11A and 11B respectively. Our masses are higher than those previously reported (13-15 MJup and 7-8 MJup) by Jayawardhana & Ivanov (2006b). Hence, we find the system is unlikely a ``planetary mass binary'', (in agreement with Luhman et al. 2007) but it has the second lowest mass and lowest binding energy of any known binary. Oph #11 and Oph #16 belong to a newly recognized population of wide (>100 AU), young (<10 Myr), roughly equal mass, VLM stellar and brown dwarf binaries. We deduce that ~6+/-3% of young (<10 Myr) VLM objects are in such wide systems. However, only 0.3+/-0.1% of old field VLM objects are found in such wide systems. Thus, young, wide, VLM binary populations may be evaporating, due to stellar encounters in their natal clusters, leading to a field population depleted in wide VLM systems.Comment: Accepted version V2. Now 13 pages longer (45 total) due to a new discussion of the stability of the wide brown dwarf binary population, new summary Figure 17 now included, Astrophysical Journal 2007 in pres
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