78 research outputs found
Detecting variability in massive astronomical time-series data. II. Variable candidates in the Northern Sky Variability Survey
We present variability analysis of data from the Northern Sky Variability Survey (NSVS). Using the clustering method, which defines variable candidates as outliers from large clusters, we cluster 16,189,040 light curves having data points at more than 15 epochs as variable and non-variable candidates in 638 NSVS fields. Variable candidates are selected depending on how strongly they are separated from the largest cluster and how rarely they are grouped together in eight-dimensional space spanned by variability indices. All NSVS light curves are also cross-correlated with IRAS, AKARI, Two Micron All Sky Survey, Sloan Digital Sky Survey (SDSS), and GALEX objects, as well as known objects in the SIMBAD database. The variability analysis and cross-correlation results are provided in a public online database, which can be used to select interesting objects for further investigation. Adopting conservative selection criteria for variable candidates, we find about 1.8 million light curves as possible variable candidates in the NSVS data, corresponding to about 10% of our entire NSVS sample. Multi-wavelength colors help us find specific types of variability among the variable candidates. Moreover, we also use morphological classification from other surveys such as SDSS to suppress spurious cases caused by blending objects or extended sources due to the low angular resolution of the NSV
Toward growth of wafer-scale single-crystal hexagonal boron nitride sheets
Hexagonal boron nitride (hBN) has a two-dimensional planar structure without dangling bonds and is considered an insulator material that can overcome the limitations of SiO2 and HfO2, which typically exhibit large densities of dangling bonds and charged impurities at the interface. However, most of the reported hBN films prepared by chemical vapor deposition (CVD) are polycrystalline with grain boundaries. The grain boundaries of a polycrystalline hBN cause current leakage and gas permeability. A recent notable study reports the growth of wafer-scale single-crystal hBN monolayer, which could mitigate the aforementioned problems caused by polycrystalline hBN films. In this perspective, we discuss the recent progress in the research on single-crystal hBN and the direction to be taken for single-crystal hBN in future. The progress is closely related to the development of a single-crystal substrate and large area of monolayer single-crystal was grown on Cu (111). In terms of the hBN growth, the next step would be to grow multilayer single-crystal hBN, which is expected to expand the scope of applications
Targeted gene suppression through double-stranded RNA application using easy-to-use methods in Arabidopsis thaliana
Abstract
RNA interference (RNAi) is an RNA-dependent gene silencing process that is regulated by the interaction between the RNA-induced silencing complex (RISC) and double-stranded RNA (dsRNA). Exogenous dsRNAs are imported directly into the cytoplasm, where they are cleaved by Dicer into short dsRNA fragments of 20–25 base pairs. These short dsRNA fragments, called small interfering RNAs (siRNAs) have sequence-specific interaction with target genes. The guide strand, onto which siRNAs are incorporated in the RISC interacts with the target mRNA sequence, thereby inducing cleavage and degradation of target messenger RNAs (mRNAs) by ribonucleases. Recent studies have shown that plant dsRNA treatments can induce RNAi. However, the dsRNA application methods and delivery systems involved have not been well examined. In this study, dsRNA was introduced to Arabidopsis thaliana by two methods: dipping and spray. We synthesized two dsRNAs designed to target mRNAs encoding enhanced green fluorescent protein (EGFP). After applying dsRNAs that target EGFP, we found an obvious reduction in GFP expression. This was determined using fluorescence microscopy and quantitative reverse transcription PCR to assess the mRNA levels of the auxin-sensitive reporter DR5-EGFP Arabidopsis thaliana. Our data revealed that applying target gene-specific exogenous dsRNAs can induce suppression of target genes of interest whether the dipping or spray method is used. This study therefore provides a foundation for understanding how to apply and deliver dsRNAs in plants
WALLABY Pilot Survey: H I gas kinematics of galaxy pairs in cluster environment
We examine the H I gas kinematics of galaxy pairs in two clusters and a group using Australian Square Kilometre Array Pathfinder (ASKAP) WALLABY pilot survey observations. We compare the H I properties of galaxy pair candidates in the Hydra I and Norma clusters, and the NGC 4636 group, with those of non-paired control galaxies selected in the same fields. We perform H I profile decomposition of the sample galaxies using a tool, BAYGAUD, which allows us to deblend a line-of-sight velocity profile with an optimal number of Gaussian components. We construct H I superprofiles of the sample galaxies via stacking of their line profiles after aligning the central velocities. We fit a double Gaussian model to the superprofiles and classify them as kinematically narrow and broad components with respect to their velocity dispersions. Additionally, we investigate the gravitational instability of H I gas discs of the sample galaxies using Toomre Q parameters and H I morphological disturbances. We investigate the effect of the cluster environment on the H I properties of galaxy pairs by dividing the cluster environment into three subcluster regions (i.e. outskirts, infalling, and central regions). We find that the denser cluster environment (i.e. infalling and central regions) is likely to impact the H I gas properties of galaxies in a way of decreasing the amplitude of the kinematically narrow H I gas (MHInarrow /MHItotal ), and increasing the Toomre Q values of the infalling and central galaxies. This tendency is likely to be more enhanced for galaxy pairs in the cluster environment
Characterization of fiber-optic light delivery and light-induced temperature changes in a rodent brain for precise optogenetic neuromodulation
Understanding light intensity and temperature increase is of considerable importance in designing or performing in vivo optogenetic experiments. Our study describes the optimal light power at target depth in the rodent brain that would maximize activation of light-gated ion channels while minimizing temperature increase. Monte Carlo (MC) simulations of light delivery were used to provide a guideline for suitable light power at a target depth. In addition, MC simulations with the Pennes bio-heat model using data obtained from measurements with a temperature-measuring cannula having 12.3 mV/°C of thermoelectric sensitivity enabled us to predict tissue heating of 0.116 °C/mW on average at target depth of 563 μm and specifically, a maximum mean plateau temperature increase of 0.25 °C/mW at 100 μm depth for 473 nm light. Our study will help to improve the design and performance of optogenetic experiments while avoiding potential over-and underillumination. © 2016 Optical Society of America.1
WALLABY Pilot Survey: HI gas kinematics of galaxy pairs in cluster environment
We examine the H I gas kinematics of galaxy pairs in two clusters and a group using Australian Square Kilometre Array Pathfinder (ASKAP) WALLABY pilot survey observations. We compare the H I properties of galaxy pair candidates in the Hydra I and Norma clusters, and the NGC 4636 group, with those of non-paired control galaxies selected in the same fields. We perform H I profile decomposition of the sample galaxies using a tool, BAYGAUD which allows us to de-blend a line-of-sight velocity profile with an optimal number of Gaussian components. We construct H I super-profiles of the sample galaxies via stacking of their line profiles after aligning the central velocities. We fit a double Gaussian model to the super-profiles and classify them as kinematically narrow and broad components with respect to their velocity dispersions. Additionally, we investigate the gravitational instability of H I gas disks of the sample galaxies using Toomre Q parameters and H I morphological disturbances. We investigate the effect of the cluster environment on the H I properties of galaxy pairs by dividing the cluster environment into three subcluster regions (i.e., outskirts, infalling and central regions). We find that the denser cluster environment (i.e., infalling and central regions) is likely to impact the H I gas properties of galaxies in a way of decreasing the amplitude of the kinematically narrow H I gas (MnarrowHI role= presentation style= box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-variant: inherit; font-stretch: inherit; line-height: normal; font-family: inherit; vertical-align: baseline; display: inline; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; position: relative; \u3eMHInarrowMnarrowHI/MtotalHI role= presentation style= box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-variant: inherit; font-stretch: inherit; line-height: normal; font-family: inherit; vertical-align: baseline; display: inline; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; position: relative; \u3eMHItotalMtotalHI), and increasing the Toomre Q values of the infalling and central galaxies. This tendency is likely to be more enhanced for galaxy pairs in the cluster environment
Multifunctional Smart Ball Sensor for Wireless Structural Health Monitoring in a Fire Situation
A variety of sensor systems have been developed to monitor the structural health status of buildings and infrastructures. However, most sensor systems for structural health monitoring (SHM) are difficult to use in extreme conditions, such as a fire situation, because of their vulnerability to high temperature and physical shocks, as well as time-consuming installation process. Here, we present a smart ball sensor (SBS) that can be immediately installed on surfaces of structures, stably measure vital SHM data in real time and wirelessly transmit the data in a high-temperature fire situation. The smart ball sensor mainly consists of sensor and data transmission module, heat insulator and adhesive module. With the integrated device configuration, the SBS can be strongly attached to the target surface with maximum adhesion force of 233.7-N and stably detect acceleration and temperature of the structure without damaging the key modules of the systems even at high temperatures of up to 500 degrees C while ensuring wireless transmission of the data. Field tests for a model pre-engineered building (PEB) structure demonstrate the validity of the smart ball sensor as an instantly deployable, high-temperature SHM system. This SBS can be used for SHM of a wider variety of structures and buildings beyond PEB structures
Factors associated with improvement or decline in cognitive function after an ischemic stroke in Korea: the Korean stroke cohort for functioning and rehabilitation (KOSCO) study
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