sj-pdf-1-cep-10.1177_03331024241230466 - Supplemental material for Vagus nerve stimulation inhibits cortical spreading depression via glutamate-dependent TrkB activation mechanism in the nucleus tractus solitarius

Supplemental material, sj-pdf-1-cep-10.1177_03331024241230466 for Vagus nerve stimulation inhibits cortical spreading depression via glutamate-dependent TrkB activation mechanism in the nucleus tractus solitarius by Tzu-Ting Liu, Shih-Pin Chen, Shuu-Jiun Wang and Jiin-Cherng Yen in Cephalalgia</p

Additional file 8 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 8: Supplemental Table 3. GIGSEA Biological Pathway Enrichment in brain tissues. The significant level of empirical P-value was 0.05 and the BayesFactor was 100. Top significantly associated pathways in these tissues that may be relevant to cluster headache were listed in the table. UsedGenes indicates number of gene used in the enrichment estimation of the GIGSEA model

Additional file 6 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 6: Supplemental Table 2. Meta-analysis of previous studies and the current study for previously reported cluster-associated loci

Additional file 3 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 3: Supplemental Figure 2. Principal component analysis (PCA) plot. The horizontal and vertical axes are the first and second dimensions from principal component analysis based on the cluster headache GWAS samples. Blue dots indicate controls and red dots indicate patients

Additional file 7 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 7: Supplemental Figure 5. eQTL analysis by MetaXca

Additional file 2 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 2: Supplemental Figure 1. Quantile-quantile plot of the GWAS results of cluster headache

Additional file 4 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 4: Supplemental Figure 3. Manhattan plot of the discovery cohort (A) and replication cohort (B)

Additional file 5 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 5: Supplemental Figure 4. Q-Q plot of the gene-based test computed by MAGMA. The horizontal axis shows -log10 p values expected under the null distribution. The vertical axis shows observed -log10 p values

Additional file 1 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 1: Supplementary Table 1. Demographics and of headache characteristics in patients with cluster headache

Additional file 9 of Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan

Additional file 9: Supplemental Figure 6. GIGSEA pathway analysis of the genes relevant to cluster headache GWAS variants