23 research outputs found

    Recent results in kaon physics

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    A review of the present experimental status of the K → πνν (Kπνν) and other kaon decay analyses at experiments NA62 (CERN) and KOTO (J-PARC) is given. The Kπνν decay is one of the best candidates among the rare meson decays for indirect searches for new physics in the mass ranges complementary to those accessible by current accelerators. The Standard Model (SM) prediction of the branching fraction (B) of the Kπνν decay is lower than 10−10 in both neutral and charged modes. The NA62 experiment aims to measure the B of the charged mode with better than 10% precision. Three candidate events, compatible with the SM prediction, have been observed from a sample of 2.12×1012 K+ decays collected in 2016 and 2017 by NA62. More than twice the statistics is available in the 2018 dataset currently being analysed. The KOTO experiment in Japan aims to measure B(KL → π0νν) using a technique similar to NA62, but with much lower momentum. In the first dataset taken in 2015 zero signal candidate events were observed. The current status of the analysis of the 2016-2018 dataset with 1.4 times more data is presented. Finally, the most recent results of other physics analyses at the NA62 experiment are summarised

    The additional value of patient-reported health status in predicting 1-year mortality after invasive coronary procedures: A report from the Euro Heart Survey on Coronary Revascularisation

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    Objective: Self-perceived health status may be helpful in identifying patients at high risk for adverse outcomes. The Euro Heart Survey on Coronary Revascularization (EHS-CR) provided an opportunity to explore whether impaired health status was a predictor of 1-year mortality in patients with coronary artery disease (CAD) undergoing angiographic procedures. Methods: Data from the EHS-CR that included 5619 patients from 31 member countries of the European Society of Cardiology were used. Inclusion criteria for the current study were completion of a self-report measure of health status, the EuroQol Questionnaire (EQ-5D) at discharge and information on 1-year follow-up, resulting in a study population of 3786 patients. Results: The 1-year mortality was 3.2% (n = 120). Survivors reported fewer problems on the five dimensions of the EQ-5D as compared with non-survivors. A broad range of potential confounders were adjusted for, which reached a p<0.10 in the unadjusted analyses. In the adjusted analyses, problems with self-care (OR 3.45; 95% CI 2.14 to 5.59) and a low rating (≤ 60) on health status (OR 2.41; 95% CI 1.47 to 3.94) were the most powerful independent predictors of mortality, among the 22 clinical variables included in the analysis. Furthermore, patients who reported no problems on all five dimensions had significantly lower 1-year mortality rates (OR 0.47; 95% CI 0.28 to 0.81). Conclusions: This analysis shows that impaired health status is associated with a 2-3-fold increased risk of all-cause mortality in patients with CAD, independent of other conventional risk factors. These results highlight the importance of including patients' subjective experience of their own health status in the evaluation strategy to optimise risk stratification and management in clinical practice

    An Economic Model for Bioprospecting Contracts

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