Laparoscopic Excision of an Omental Leiomyoma with a Giant Cystic Component

This case report suggests that laparoscopic resection of omental leiomyoma with a large cystic component is feasible and safe

Phytochemical profiling, antimicrobial and anticancer potential of Rosmarinus officinalis growing in Kashmir Himalayan region

Currently, medicinal plants are gaining importance in pharmaceutical and scientific communities. Medicinal plants are the most abundant natural source of valuable phytochemicals, which can help treat human diseases. The present study aimed to do phytochemical profiling and assess the antimicrobial and anticancer activity of the methanolic leaf extract of Rosmarinus officinalis. The photochemical profiling of R. officinalis leaves was done by GC-MS analysis. Twenty-six compounds were identified from the leaf extracts with great significance in pharmaceutical science for therapeutically efficient formulations to combat various diseases. The antimicrobial activity was done by the well diffusion method, while the anticancer potential against the A549 lung cancer cell line by MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. The highest zone of inhibition was seen against Escherichia coli ATCC 11229 (21 ± 0.7 mm), Enterococcus faecalis ATCC 29212 (19 ± 0.8 mm), Candida albicans ATCC 10231 (18± 0.6 mm) followed by Staphylococcus aureus ATCC 25923 (18 ± 0.8 mm) and Pseudomonas aeruginosa (11 ± 0.5 mm) with MIC values ranging from 128 to 256 µg/mL. R. officinalis demonstrated significant (p ≤ 0.05) anticancer activity against the A549 cancer cell line with IC50 values of 39.70 and 33.60 µg/mL for 24 and 48 hours, respectively. The methanolic extract of R. officinalis can be a potential antimicrobial and anticancer agent and a vital resource for developing new drugs.

Video assisted thoracic surgery in children

Thoracoscopic surgery, i.e., video assisted thoracic surgery (VATS) has been in use in children for last 98 years. Its use initially was restricted to the diagnostic purposes. However, with the improvement in the optics, better understanding of the physiology with CO2 insufflation, better capabilities in achieving the single lung ventilation and newer vessel sealing devices have rapidly expanded the spectrum of the indication of VATS. At present many complex lung resections, excision of mediastinal tumors are performed by VATS in the experienced centre. The VATS has become the standard of care in empyema, lung biopsy, Mediastinal Lymphnode biopsy, repair of diaphragmatic hernia, etc. The article discusses the indications of VATS, techniques to achieve the selective ventilation and surgical steps in the different surgical conditions in children

Incise, dissect, excise and suture technique of laparoscopic repair of paediatric male inguinal hernia

Background: Authors report incise, dissect, excise and suture (IDES) technique of laparoscopic repair of paediatric male inguinal hernia (LRPMIH). This series retrospectively evaluates a consecutive personal series of children undergoing laparoscopic hernia repair by this new technique. Materials and Methods: It is a retrospective review of the LRPMIH done by single surgeon from January 2001 to December 2007. All male patients who were referred to the first author for management of inguinal hernia were given the option of laparoscopic repair. Parents who gave consent for their child to undergo LRPMIH were retrospectively reviewed. Results: A total of 155 patients were operated. Age group was 2 months to 13 years (average-5 years). Follow-up period ranges from 1 to 7 years. Average operating time was 29 min for unilateral and 40 min for bilateral inguinal hernia. Maximum time required was 50 min which was for bilateral inguinal hernia. Bilateral inguinal hernia was present in 10 (6.4%) patients. There were no intraoperative complications. Contralateral processus vaginalis was patent in 25 (16.12%) patients. In the immediate post-operative period 8 patients had port site surgical emphysema which resolved on its own. There are no recurrences so far. One patient developed port site hernia, which was repaired with the standard surgery. There is no incidence of clinical testicular atrophy. Conclusion: LRPMIH can be done as routine procedure and also has fewer complications. It has advantage of diagnosing and repairing contra lateral patent processus vaginalis. However a double-blind controlled study is required to establish the results

Video assisted thoracic surgery in children

Thoracoscopic surgery, i.e., video assisted thoracic surgery (VATS) has been in use in children for last 98 years. Its use initially was restricted to the diagnostic purposes. However, with the improvement in the optics, better understanding of the physiology with CO2 insufflation, better capabilities in achieving the single lung ventilation and newer vessel sealing devices have rapidly expanded the spectrum of the indication of VATS. At present many complex lung resections, excision of mediastinal tumors are performed by VATS in the experienced centre. The VATS has become the standard of care in empyema, lung biopsy, Mediastinal Lymphnode biopsy, repair of diaphragmatic hernia, etc. The article discusses the indications of VATS, techniques to achieve the selective ventilation and surgical steps in the different surgical conditions in children

Laparoscopic repair of Morgagni′s hernia: An innovative approach

Aim: To review our experience of laparoscopic repair of Morgagni′s hernia (MH) using transfascial sutures. Materials and Methods: This is a retrospective review of patients presenting to the first author with the diagnosis of MH over a 15-year period. The variables analyzed included demographic data, clinical presentation, and operative details. Results: In all there were five male with a median age of 2 years. They were asymptomatic and MH was detected incidentally by observing an air-filled density in the right cardiophrenic angle on plain X-ray of the chest. Computed tomography (CT) confirmed the diagnosis in all patients. All patients underwent laparoscopic repair of MH using transfascial sutures. The average operative time was 75 min. Oral feeding was started 6 h after surgery and patients were discharged on either 3 rd or 4 th postoperative day. Postoperative follow-up X-ray confirmed the intact repair. Conclusions: Laparoscopic repair of MH using transfascial sutures is an easy and effective solution. Multiple horizontal mattress sutures taking full thickness of abdominal wall muscles with the edge of the diaphragm leads to a strong repair. As sutures are tied extracorporeally, the technique is easily reproducible

Single-incision laparoscopic cholecystectomy: How I do it?

Single-incision laparoscopic cholecystectomy (SILC) is a relatively new technique that is being increasingly used by surgeons around the world. Unlike the multi-port cholecystectomy, a standardised technique and detailed description of the operative steps of SILC is lacking in the literature. This article provides a stepwise account of the technique of SILC aimed at surgeons wishing to learn the procedure. A brief review of the current literature on SILC follows

Single-incision laparoscopic cholecystectomy: How I do it?

Single-incision laparoscopic cholecystectomy (SILC) is a relatively new technique that is being increasingly used by surgeons around the world. Unlike the multi-port cholecystectomy, a standardised technique and detailed description of the operative steps of SILC is lacking in the literature. This article provides a stepwise account of the technique of SILC aimed at surgeons wishing to learn the procedure. A brief review of the current literature on SILC follows