Relationship between entrepreneurial self-efficacy and entrepreneurial intention in medical library and information science students: an Iranian perspective

Purpose: The main purpose of this study is to investigate the relationship between entrepreneurial self-efficacy and entrepreneurial intention of students in the field of medical library and information science. Methods: This study quantitatively examined seven hypotheses through Structural Equation Modeling (SEM) techniques. Using the census method, 79 students of medical library and information science of Hamadan University of Medical Sciences, Iran, were studied. Data was collected using the Entrepreneurial Self-efficacy Questionnaire proposed by De Noble et al. (1999) and the Entrepreneurial Intention Questionnaire presented by the Linan and Chen (2011). Descriptive and inferential data analysis was performed using SPSS and SmartPLS2 software at a significance level of 0.05. Results: The results showed that the variable of entrepreneurial self-efficacy and the components of initiating investor relationships and developing human resources affect the entrepreneurial intention of students, while the components of Understanding market opportunities, building an innovative environment, defining core purpose, and coping with challenges had no effect on entrepreneurship. The entrepreneurial intention of medical library and information science students is positively affected by their entrepreneurial self-efficacy. Greater self- efficacy leads to entrepreneurship. Practical implications: Considering the positive effect of entrepreneurial self-efficacy on students\u27 entrepreneurial intention, offering training courses to strengthen entrepreneurial behavior in the academic period seems useful. Originality/value: Entrepreneurship helps communities achieve social and economic growth. Entrepreneurial intention is one of the important factors in the occurrence of entrepreneurial behavior in students. Entrepreneurial Self-efficacy is a key factor in shaping and strengthening entrepreneurial intention. Given the increasing number of library and medical information science graduates and the relatively limited job market in this field, it seems useful to examine their entrepreneurial intention and the impact of social factors affecting it. Keywords: Entrepreneurial Self-efficacy, Entrepreneurial Intention, Medical Library and Information scienc

Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Funding: F Carvalho and E Fernandes acknowledge support from Fundação para a Ciência e a Tecnologia, I.P. (FCT), in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences UCIBIO and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy i4HB; FCT/MCTES through the project UIDB/50006/2020. J Conde acknowledges the European Research Council Starting Grant (ERC-StG-2019-848325). V M Costa acknowledges the grant SFRH/BHD/110001/2015, received by Portuguese national funds through Fundação para a Ciência e Tecnologia (FCT), IP, under the Norma Transitória DL57/2016/CP1334/CT0006.proofepub_ahead_of_prin

Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019.

The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world.Funding/Support: The Institute for Health Metrics and Evaluation received funding from the Bill & Melinda Gates Foundation and the American Lebanese Syrian Associated Charities. Dr Aljunid acknowledges the Department of Health Policy and Management of Kuwait University and the International Centre for Casemix and Clinical Coding, National University of Malaysia for the approval and support to participate in this research project. Dr Bhaskar acknowledges institutional support from the NSW Ministry of Health and NSW Health Pathology. Dr Bärnighausen was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, which is funded by the German Federal Ministry of Education and Research. Dr Braithwaite acknowledges funding from the National Institutes of Health/ National Cancer Institute. Dr Conde acknowledges financial support from the European Research Council ERC Starting Grant agreement No 848325. Dr Costa acknowledges her grant (SFRH/BHD/110001/2015), received by Portuguese national funds through Fundação para a Ciência e Tecnologia, IP under the Norma Transitória grant DL57/2016/CP1334/CT0006. Dr Ghith acknowledges support from a grant from Novo Nordisk Foundation (NNF16OC0021856). Dr Glasbey is supported by a National Institute of Health Research Doctoral Research Fellowship. Dr Vivek Kumar Gupta acknowledges funding support from National Health and Medical Research Council Australia. Dr Haque thanks Jazan University, Saudi Arabia for providing access to the Saudi Digital Library for this research study. Drs Herteliu, Pana, and Ausloos are partially supported by a grant of the Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI, project number PN-III-P4-ID-PCCF-2016-0084. Dr Hugo received support from the Higher Education Improvement Coordination of the Brazilian Ministry of Education for a sabbatical period at the Institute for Health Metrics and Evaluation, between September 2019 and August 2020. Dr Sheikh Mohammed Shariful Islam acknowledges funding by a National Heart Foundation of Australia Fellowship and National Health and Medical Research Council Emerging Leadership Fellowship. Dr Jakovljevic acknowledges support through grant OI 175014 of the Ministry of Education Science and Technological Development of the Republic of Serbia. Dr Katikireddi acknowledges funding from a NHS Research Scotland Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC_UU_00022/2), and the Scottish Government Chief Scientist Office (SPHSU17). Dr Md Nuruzzaman Khan acknowledges the support of Jatiya Kabi Kazi Nazrul Islam University, Bangladesh. Dr Yun Jin Kim was supported by the Research Management Centre, Xiamen University Malaysia (XMUMRF/2020-C6/ITCM/0004). Dr Koulmane Laxminarayana acknowledges institutional support from Manipal Academy of Higher Education. Dr Landires is a member of the Sistema Nacional de Investigación, which is supported by Panama’s Secretaría Nacional de Ciencia, Tecnología e Innovación. Dr Loureiro was supported by national funds through Fundação para a Ciência e Tecnologia under the Scientific Employment Stimulus–Institutional Call (CEECINST/00049/2018). Dr Molokhia is supported by the National Institute for Health Research Biomedical Research Center at Guy’s and St Thomas’ National Health Service Foundation Trust and King’s College London. Dr Moosavi appreciates NIGEB's support. Dr Pati acknowledges support from the SIAN Institute, Association for Biodiversity Conservation & Research. Dr Rakovac acknowledges a grant from the government of the Russian Federation in the context of World Health Organization Noncommunicable Diseases Office. Dr Samy was supported by a fellowship from the Egyptian Fulbright Mission Program. Dr Sheikh acknowledges support from Health Data Research UK. Drs Adithi Shetty and Unnikrishnan acknowledge support given by Kasturba Medical College, Mangalore, Manipal Academy of Higher Education. Dr Pavanchand H. Shetty acknowledges Manipal Academy of Higher Education for their research support. Dr Diego Augusto Santos Silva was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil Finance Code 001 and is supported in part by CNPq (302028/2018-8). Dr Zhu acknowledges the Cancer Prevention and Research Institute of Texas grant RP210042

Tobacco Use Prevention by Integrating inside and outside of School Based Programs: a Systematic Review

Background: Experience of tobacco use in early ages will increase probability of addiction to nicotine therefore, efficient tobacco control programs for teenagers are crucial. This study was conducted to recognize elements of successful integrated inside and outside of school based smoking prevention programs. Methods: MeSH terms and related keywords were used to search PubMed, Cochrane, Medline, EMBASE, ERIC, SID databases from inception to 29th October 2013. Trials with random and non-random designs, systematic reviews and cohort studies that assessed or reported application of integrated tobacco control programs were included. Quality of the retrieved publications was checked independently by the authors and any disagreement was resolved by consensus. Result: Among the 745 identified publications, only 15 studies had the inclusion criteria with a considerable methodological heterogeneity. While, precise out-come of integrated out of school/school-based interventions were not percepti-ble but this study’s findings implied that outside of school intervention could strengthen school-based tobacco prevention programs. No study was found to examine school-based interventions integrated with primary health care such as anti-tobacco consultations, high-risk students screening and their referral to special centers. Conclusion: Integration of outside and inside of school-based programs may boost probability of obtaining favorable outcomes and success rate in practice

Survey on Ionizing Radiation Including Gamma-Ray Exposure among the Medical Staff Working in the Non-Intensive Ward of Farshchian Cardiovascular Hospital in Hamadan, Iran

Background and Objective: With the increase of cardiovascular diseases worldwide, diagnostic and therapeutic measures, particularly nuclear medicine technology, have also increased. A multiplicity of diagnostic procedures are used for treating many patients with cardiovascular diseases in Farshchian Cardiovascular Hospital, Hamadan, Iran; therefore, the staff of this hospital, especially non-intensive care workers, have encountered a large number of these patients and have fear and concerns caused by this exposure. In this regard, this study aimed to determine the exposure of staff working in non-intensive care units of this Cardiovascular Hospital to ionizing radiation, including gamma-ray. Materials and Methods: This cross-sectional study was conducted in which 40 film badges (for radiation measurement) were attached to staff working in two separated inpatient wards (Ward A and Ward B) from non-intensive wards of Farshchian Cardiovascular Hospital in three separate shifts (morning, evening, and night) and in three occupational categories, including nurses, health workers, and service provider staff.[A1]  The amount of radiation exposure of people (in mSv) was measured in two separate sections for four mounths (the first two months, the second two months) and SPSS version 26 software was used to analyze the data. Results: Exposure to ionizing radiation, including gamma-ray, in all three occupational categories of nurses, health workers, and service providers was less than 0.05 mSv in both wards, all below the risk threshold. Conclusion: The results of this study showed that the exposure of nurses, health workers, and service providers working in the studied wards to ionizing radiation (e.g., gamma-ray) was within the permissible limit; therefore, the working environment of these employees is safe to take care of patients  [A1]There is one sentence in Persian abstract which was not translated here. Please check

A Review of Applications of Nanoceria in Cancer

Cancer is one of the most difficult diseases to treat in modern medicine. Annually, many articles are published that propose various ways for preventing carcinogenesis. Furthermore, research into cancer treatments is carried out with minimal side effects. The most common non-invasive cancer treatments include chemotherapy, targeted therapy, radiotherapy, and immunotherapy. Low effectiveness of chemo-radiation therapy and normal tissue toxicity caused by these treatments are two of the most difficult challenges. Some medicines have been recommended as adjuvants to increase tumor responses while also reducing normal tissue damage. Cerium oxide as a nanoparticle (nanoceria, CNPs) has recieved a lot of interest as a way to control tumor and normal tissue responses to various cancer treatment regimens. In vitro and in vivo studies demonstrate that it can reduce chemo-radiation toxicity in normal tissues as an antioxidant and anti-inflammatory agent. Furthermore, it has the ability to make cancer cells more sensitive to both chemotherapy and radiotherapy. In this paper, we reviewed the potential role of nanoceria for preserving normal tissues and sensitization of cancer cells in combination with different cancer treatment modalities

Vaccine-Derived Polioviruses and Children with Primary Immunodeficiency, Iran, 1995–2014

Widespread use of oral poliovirus vaccine has led to an ≈99.9% decrease in global incidence of poliomyelitis (from ≈350,000 cases in 1988 to 74 cases in 2015) and eradication of wild-type poliovirus serotypes 2 and 3. However, patients with primary immunodeficiency might shed vaccine-derived polioviruses (VDPVs) for an extended period, which could pose a major threat to polio eradication programs. Since 1995, sixteen VDPV populations have been isolated from 14 patients with immunodeficiency in Iran. For these patients, vaccine-associated paralysis, mostly in >1 extremity, was the first manifestation of primary immunodeficiency. Seven patients with humoral immunodeficiency cleared VDPV infection more frequently than did 6 patients with combined immunodeficiencies. Our results raise questions about manifestations of VDPVs in immunodeficient patients and the role of cellular immunity against enterovirus infections. On the basis of an association between VDPVs and immunodeficiency, we advocate screening of patients with primary immunodeficiency for shedding of polioviruses