The footprint of large scale cosmic structure on the ultra-high energy cosmic ray distribution

Current experiments collecting high statistics in ultra-high energy cosmic rays (UHECRs) are opening a new window on the universe. In this work we discuss a large scale structure model for the UHECR origin which evaluates the expected anisotropy in the UHECR arrival distribution starting from a given astronomical catalogue of the local universe. The model takes into account the main selection effects in the catalogue and the UHECR propagation effects. By applying this method to the IRAS PSCz catalogue, we derive the minimum statistics needed to significatively reject the hypothesis that UHECRs trace the baryonic distribution in the universe, in particular providing a forecast for the Auger experiment.Comment: 21 pages, 14 figures. Reference added, minor changes, matches published versio

Spin-wave instabilities in spin-transfer-driven magnetization dynamics

We study the stability of magnetization precessions induced in spin-transfer devices by the injection of spin-polarized electric currents. Instability conditions are derived by introducing a generalized, far-from-equilibrium interpretation of spin-waves. It is shown that instabilities are generated by distinct groups of magnetostatically coupled spin-waves. Stability diagrams are constructed as a function of external magnetic field and injected spin-polarized current. These diagrams show that applying larger fields and currents has a stabilizing effect on magnetization precessions. Analytical results are compared with numerical simulations of spin-transfer-driven magnetization dynamics.Comment: 4 pages, 2 figure

The Milky Way as a Kiloparsec-Scale Axionscope

Very high energy gamma-rays are expected to be absorbed by the extragalactic background light over cosmological distances via the process of electron-positron pair production. Recent observations of cosmologically distant gamma-ray emitters by ground based gamma-ray telescopes have, however, revealed a surprising degree of transparency of the universe to very high energy photons. One possible mechanism to explain this observation is the oscillation between photons and axion-like-particles (ALPs). Here we explore this possibility further, focusing on photon-ALP conversion in the magnetic fields in and around gamma-ray sources and in the magnetic field of the Milky Way, where some fraction of the ALP flux is converted back into photons. We show that this mechanism can be efficient in allowed regions of the ALP parameter space, as well as in typical configurations of the Galactic Magnetic Field. As case examples, we consider the spectrum observed from two HESS sources: 1ES1101-232 at redshift z=0.186 and H 2356-309 at z=0.165. We also discuss features of this scenario which could be used to distinguish it from standard or other exotic models.Comment: 7 pages, 4 figures. Matches published versio

Cosmological implications of the KATRIN experiment

The upcoming Karlsruhe Tritium Neutrino (KATRIN) experiment will put unprecedented constraints on the absolute mass of the electron neutrino, \mnue. In this paper we investigate how this information on \mnue will affect our constraints on cosmological parameters. We consider two scenarios; one where \mnue=0 (i.e., no detection by KATRIN), and one where \mnue=0.3eV. We find that the constraints on \mnue from KATRIN will affect estimates of some important cosmological parameters significantly. For example, the significance of $n_s<1$ and the inferred value of $\Omega_\Lambda$ depend on the results from the KATRIN experiment.Comment: 13 page

Using BBN in cosmological parameter extraction from CMB: a forecast for Planck

Data from future high-precision Cosmic Microwave Background (CMB) measurements will be sensitive to the primordial Helium abundance $Y_p$. At the same time, this parameter can be predicted from Big Bang Nucleosynthesis (BBN) as a function of the baryon and radiation densities, as well as a neutrino chemical potential. We suggest to use this information to impose a self-consistent BBN prior on $Y_p$ and determine its impact on parameter inference from simulated Planck data. We find that this approach can significantly improve bounds on cosmological parameters compared to an analysis which treats $Y_p$ as a free parameter, if the neutrino chemical potential is taken to vanish. We demonstrate that fixing the Helium fraction to an arbitrary value can seriously bias parameter estimates. Under the assumption of degenerate BBN (i.e., letting the neutrino chemical potential $\xi$ vary), the BBN prior's constraining power is somewhat weakened, but nevertheless allows us to constrain $\xi$ with an accuracy that rivals bounds inferred from present data on light element abundances.Comment: 14 pages, 4 figures; v2: minor changes, matches published versio

Parallel pumping of magnetic vortex gyrations in spin-torque nano-oscillators

We experimentally demonstrate that large magnetic vortex oscillations can be parametrically excited in a magnetic tunnel junction by the injection of radio-frequency (rf) currents at twice the natural frequency of the gyrotropic vortex core motion. The mechanism of excitation is based on the parallel pumping of vortex motion by the rf orthoradial field generated by the injected current. Theoretical analysis shows that experimental results can be interpreted as the manifestation of parametric amplification when rf current is small, and of parametric instability when rf current is above a certain threshold. By taking into account the energy nonlinearities, we succeed to describe the amplitude saturation of vortex oscillations as well as the coexistence of stable regimes.Comment: Submitted to Phys. Rev. Let

Dynamical Dark Energy model parameters with or without massive neutrinos

We use WMAP5 and other cosmological data to constrain model parameters in quintessence cosmologies, focusing also on their shift when we allow for non-vanishing neutrino masses. The Ratra-Peebles (RP) and SUGRA potentials are used here, as examples of slowly or fastly varying state parameter w(a). Both potentials depend on an energy scale \Lambda. Here we confirm the results of previous analysis with WMAP3 data on the upper limits on \Lambda, which turn out to be rather small (down to ~10^{-9} in RP cosmologies and ~10^{-5} for SUGRA). Our constraints on \Lambda are not heavily affected by the inclusion of neutrino mass as a free parameter. On the contrary, when the neutrino mass degree of freedom is opened, significant shifts in the best-fit values of other parameters occur.Comment: 9 pages, 3 figures, submitted to JCA

HSP 27 aspossible prognostic factor in patients with oral squamous cell carcinoma.

Summary. HSP27 belongs to the Heat shock protein (HSP) family, which plays essential functions in cells under physiological conditions and prevents stressinduced cellular damage. The aim of this study was to investigate the biological role of HSP27 in oral tumorigenesis. Materials and methods: Seventy-nine cases of oral squamous cell carcinoma and 10 cases of normal mucosa were analysed for HSP27 expression by immunohistochemistry. Moreover, the western blot analysis was performed on two cases of normal mucosa and five cases of OSCC. Results: Normal oral mucosa showed a suprabasal expression of HSP27. Twenty-four cases of SCC (30.7%) showed a diffuse staining for HSP27, and 48 cases (60.3%) showed instead a decrease in staining, which was diffuse, homogeneous, or with alternation of positive and negative areas in a single tumor (“mosaic” pattern). Only 7 cases of OSCC (7.5%) were completely negative for HSP27. Frequency of lymph node metastases was higher in HSP27-negative tumours (3/7, 42.8%) than in HSP-reduced (16/48, 33.3%) or positive ones (5/26, 19.2%). Regard staging, stages I and II had a higher score than stages III and IV (stage I > stage II > stage III > stage IV). There was also a statistically significant correlation between HSP27 expression and grade: HSP27 expression was reduced in poorly differentiated tumours (P < 0.05). When analysed for prognostic significance, patients with negative/reduced HSP27 expression had poorer survival rates than the group with positive HSP27 expression (P < 0.05). The statistical analysis of these findings showed no significant correlation between HSP27 expression, sex, and tumour size. Conclusion: Cases with reduced expression were more aggressive and poorly differentiated. These data suggest that HSP27 expression may be useful in order to identify cases of oral squamous cell carcinoma with more aggressive and invasive phenotype providing novel diagnostic and prognostic information on individual patient survival with oral cancers

MeV-mass dark matter and primordial nucleosynthesis

The annihilation of new dark matter candidates with masses $m_X$ in the MeV range may account for the galactic positrons that are required to explain the 511 keV $\gamma$-ray flux from the galactic bulge. We study the impact of MeV-mass thermal relic particles on the primordial synthesis of $^2$H, $^4$He, and $^7$Li. If the new particles are in thermal equilibrium with neutrinos during the nucleosynthesis epoch they increase the helium mass fraction for m_X\alt 10 MeV and are thus disfavored. If they couple primarily to the electromagnetic plasma they can have the opposite effect of lowering both helium and deuterium. For $m_X=4$--10 MeV they can even improve the overall agreement between the predicted and observed $^2$H and $^4$He abundances.Comment: 11 pages, 10 figures, references and two appendices added, conclusions unchanged; accepted for publication in Phys.Rev.