Comparison of immunoglobulin (IgG, IgM) concentrations in calves raised under organic and conventional conditions*

The objective of study was conducted on to compare immunoglobulin (Ig) concentrations in calves raised under organic and conventional conditions. 30 newborn Holstein Friesian calves (15 rose under organic and 15 under conventional conditions) in two dairy cattle farms. Blood samples were taken from 30 newborn calves at birth (before taking colostrum) and on 14th day to compare immunoglobulin (Ig) concentrations in calves raised under organic and conventional conditions. Furthermore, blood and colostrum samples were also taken from the mothers included into the study. IgG and IgM concentrations in colostrum and blood serums were determined using commercial ELISA kits. IgG concentrations at birth (0.79±0.34, 1.64±0.95 mg/mL) and on the 14th day (46.5±21.5, 70.5±27.8 mg/mL) in calves raised under organic conditions were lower than those raised under conventional conditions (p0.05). No difference was found in the IgG and IgM concentrations of colostrum obtained from cows raised under organic and conventional conditions. In both the husbandry systems, positive and significant (p<0.01) correlations were found between the Ig concentrations of the mothers and offsprings. Consequently, it can be suggested that higher Ig concentrations in cattle raised under conventional conditions might be due to poorer environmental conditions

Frequency of uveitis and its associations with HLA B27 in ankylosing spondylitis patients

Aim: To investigate the prevalence of uveitis in ankylosing spondylitis (AS) patients and its relationship with HLA B27. Methods: The data of 95 patients with AS who admitted to Tokat Gaziosmanpaşa University Internal Medicine and Rehabilitation Outpatient Clinics between 2010 and 2019 were analyzed retrospectively. Demographic characteristics, HLA B27 positivity and detailed eye consultation notes of the patients were recorded. Results: Of the 95 patients, 65 (68%) were male and 30 (32%) were female. The mean age of the patients was 38.3 ± 11.6 years. The HLA B27 results of 10 patients could not be reached. 22% of the patients had at least one episode of uveitis attack. While 82% (70/85) of patients had HLA B27 positivity, this rate was 86% in (18/21) patients with uveitis. Conclusion: Uveitis is a disease that can cause permanent loss of vision. In our study, no significant difference was found between the presence of uveitis and the presence of HLA B27 in patients with AS and this finding needs to be supported by randomized studies

Occurrence and Timing of Complications of Crown-Fractures in Permanent Incisors: A Randomized Clinical Trial

Objective: To investigate the complications of crown fractures that might occur in different follow-up periods. Material and Methods: Individuals within the 6-13 age range with crown fracture and consulted to University Hospital were included in the study. Patients were randomly divided into three groups by block randomization method and evaluated clinical and radiographically for complications at the 6, 8 weeks, and 6, 12, 24 months. The crown of the tooth was divided into 9 equal squares and 6 classes of fracture types were created. Complications and their frequencies were evaluated based on the post-traumatic substance losses in these illustrated fracture types. Results: The incidence of complications was 28.9% at 6 months, 51.3% at 1year, and 63.9% at 2years. Class4 fractures had the highest probability of complications (32.4%) and the development of pulp necrosis (40.3%). It was detected that the complications such as pulp necrosis (21.6%) can be frequently observed in the 2nd year or later periods of crown fractures. Conclusion: In addition to current regular checks, periodic follow-up of crown fracture should be extended to reflect current findings. Dentists, patients, and their parents must be made conscious of the importance of the treatment and follow-ups of crown fracture

“AgiLean PM” – A UNIFIYING STRATEGIC FRAMEWORK TO MANAGE CONSTRUCTION PROJECTS

A challenge in Lean Construction is how to make it applicable when there is a high degree of complexity and uncertainty. In many construction projects there are changing project requirements, unique products and a need for actions that are highly focused on meeting customer/client expectations. Such scenarios require management methods that are characterised by being flexible and able to react to change. The aim of this thesis is to introduce a method that has such characteristics. Project Management, Lean and Agile paradigms are merged through the application of the fission and fusion approach of nuclear physics. This research is facilitated through a sequential explorative method. In the first instance, interviews with 22 practitioners in the fields of construction project management, Lean and Agile have been conducted. Then a quantitative self-administered questionnaire with 213 useful responses has been utilised to validate the transferability of the interview findings. It is concluded that Lean is not ideally suited to dealing with the dynamic nature of construction projects. Agile methods, which were developed to cope with the high levels of uncertainty inherent to IT projects, are more flexible and able to react to change. Hence utilising Agile-based methods might be the key to the successful utilization of Lean in construction. Therefore a management method based on combining Lean and Agile approaches has potential. Such an approach needs creative thinking to develop a solution that is different to that of “Leagile”. Leagile uses Lean and Agile methods in the execution phase sequentially, through using a decoupling point model to separate the two. This thesis introduces a new paradigm in which such a decoupling or separation does not take place. Rather, project management, Lean and Agile have been merged together to develop a new holistic and strategic framework. The paradigm presented in this thesis is termed “AgiLean Project Management”

Therapeutic effect of astaxanthin on 5-fluorouracil-induced ovarian damage in rats

Although astaxanthin (ASX) is one of the most studied antioxidant molecules, its curative effect against ovarian damage caused by 5-fluorouracil (5-FU) has not been demonstrated to date. It was therefore aimed to investigate whether ASX is therapeutic against 5-FU-induced ovotoxicity in this study. Rats were first exposed to 5-FU (100 mg/kg) and then treated ASX (250 μg/kg) for three days. Oxidative stress (OS), inflammation and apoptosis markers were determined using spectrophotometric methods. Ovarian tissues were also evaluated histologically. The levels of OS, inflammation and apoptosis biomarkers increased by 5-FU administration (p&lt;0.05). Treatment with ASX significantly alleviated these markers (p&lt;0.05). These findings reveal that ASX may exert an ovoprotective effect by reducing pro-inflammatory mediators and enhancing antioxidant status in ovarian tissue

Hepatik Bileşkede Hiler Kolanjiokarsinomayı Taklit Eden Tip IV Mirizzi Sendromu

Mirizzi’s syndrome refers to common bile duct obstruction resulting from compression by a gallstone impacted in the cystic duct or neck of the gallbladder. Some cases can not be identified preoperatively, despite modern imaging techniques. Today, treatment of Mirizzi syndrome is surgical. The essential part of the management of patients with Mirizzi syndrome is to determine the best surgical procedure in the preoperative period. In type I patients, simple cholecystectomy is generally enough, but types IIIV require more complex surgical approach, such as cholecystectomy and bilioenteric anastomosis. Here, we presented a 48 year-old man with obstructive jaundice who diagnosed as Mirizzi’s syndrome.Mirizzi sendromu, sistik kanal ya da safra kesesi boynuna impakte taşın, koledok kanalına dıştan basısı sonucu gelişir. Modern görüntüleme tekniklerine rağmen bazı olgular ameliyat öncesi dönemde belirlenememektedir. Mirizzi sendromunun günümüzdeki tedavisi cerrahidir. Mirizzi Sendrom tanılı hastalarda tedavide en önemli noktalardan biri de preoperatif dönemde cerrahi tedavinin belirlenmesidir. Tip I olgularda basit kolesistektomi yeterli olurken, Tip II-IV MS olguları kolesistektomi ve biliyoenterik anastomoz gibi kompleks prosedürler gerektirebilir. Burada tıkanma sarılığı ile müracaat eden, Mirizzi sendromu tespit edilen 48 yaşında bir erkek hasta sunulmuştur

Unified resource allocation and mobility management technique using particle swarm optimization for VLC networks

In this paper, we present a unified resource allocation and mobility management algorithm based on particle swarm optimization (PSO) for indoor visible light communication (VLC) networks. We consider a VLC network where multiple LEDs serve as access points (APs). A centralized controller collects channel state information, quality of service requirements of the users, and the overload status of the APs. Based on the available information, in each time interval, the controller decides which user is served by which AP and assigns subcarriers to the users with the objective of maximizing both the system throughput and user satisfaction. We formulate the resource allocation problem as a constrained nonlinear integer programming problem and solve it using meta-heuristic PSO. Through an extensive simulation study, the superiority of the proposed algorithm in terms of system throughput and user satisfaction over round robin, best channel quality information, and genetic algorithms is demonstrated.Council for Scientific and Industrial ResearchPublisher versio