143 research outputs found

    A New Method for Assessing the Resiliency of Large, Complex Networks

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    Designing resilient and reliable networks is a principle concern of planners and private firms. Traffic congestion whether recurring or as the result of some aperiodic event is extremely costly. This paper describes an alternative process and a model for analyzing the resiliency of networks that address some of the shortcomings of more traditional approaches – e.g., the four-step modeling process used in transportation planning. It should be noted that the authors do not view this as a replacement to current approaches but rather as a complementary tool designed to augment analysis capabilities. The process that is described in this paper for analyzing the resiliency of a network involves at least three steps: 1. assessment or identification of important nodes and links according to different criteria 2. verification of critical nodes and links based on failure simulations and 3. consequence. Raster analysis, graph-theory principles and GIS are used to develop a model for carrying out each of these steps. The methods are demonstrated using two, large interdependent networks for a metropolitan area in the United States.

    Biomolecular mechanisms of staphylococcal biofilm formation

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    The multitude of biomolecular and regulatory factors involved in staphylococcal adhesion and biofilm formation owe much to their ability to colonize surfaces, allowing the biofilm form to become the preferential bacterial phenotype. Judging by total number, biomass and variety of environments colonized, bacteria can be categorized as the most successful lifeform on earth. This is due to the ability of bacteria and other microorganisms to respond phenotypically via biomolecular processes to the stresses of their surrounding environment. This review focuses on the specific pathways involved in the adhesion of the Gram-positive bacteria Staphylococcus epidermidis and Staphylococcus aureus with reference to the role of specific cell surface adhesins, the ica operon, accumulation-associated proteins and quorum-sensing systems and their significance in medical device-related infection

    A New Method for Assessing the Resiliency of Large, Complex Networks

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    Designing resilient and reliable networks is a principle concern of planners and private firms. Traffic congestion whether recurring or as the result of some aperiodic event is extremely costly. This paper describes an alternative process and a model for analyzing the resiliency of networks that address some of the shortcomings of more traditional approaches – e.g., the four-step modeling process used in transportation planning. It should be noted that the authors do not view this as a replacement to current approaches but rather as a complementary tool designed to augment analysis capabilities. The process that is described in this paper for analyzing the resiliency of a network involves at least three steps: 1. assessment or identification of important nodes and links according to different criteria 2. verification of critical nodes and links based on failure simulations and 3. consequence. Raster analysis, graph-theory principles and GIS are used to develop a model for carrying out each of these steps. The methods are demonstrated using two, large interdependent networks for a metropolitan area in the United States

    Network Analysis of Commuting Flows: A Comparative Static Approach to German Data

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    Abstract The analysis of complex networks has recently received considerable attention. The work by Albert and Barabási presented a research challenge to network analysis, that is, growth of the network. The present paper offers a network analysis of the spatial commuting network in Germany. First, we study the spatial evolution of the commuting network over time. Secondly, we compare two spatial interaction model (SIM) specifications, in order to replicate the actual network structure. Our findings suggest that the commuting network appeared to become more dense and clustered, while the SIMs seem to require more sophisticated specifications, in order to replicate such a connectivity structure
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