4,158 research outputs found
Innovative Opportunities for Elementary and Middle School Teachers to Maintain Currency in Mathematics and Science: A Community College-School System Partnership
Since 1992 the Manassas Campus of Northern Virginia Community College – in response to requests from local school systems – has developed four innovative methods of assisting elementary, secondary and middle school teachers to enhance their content knowledge in science and mathematics, as well as integrate curriculum units for classroom presentation. These methods are based on the assumptions that: - While teachers at this level have fundamental understanding of math and science, if they wish to incorporate new concepts or technologies from these fields, graduate level content courses are generally beyond their background level. - Community College faculty can often provide a bridge that connects advanced content in science and mathematics with the applications that can be adapted to elementary/middle school curriculum. - Presenting content to a mixed audience of teachers from K-8 allows teachers to see how content can be adapted to grade levels above and below. - Content delivery methods must be interactive and must be responsive to the multiple demands on these teachers’ time. This requires flexibility in scheduling and course requirements
The ecology, biogeography, history and future of two globally important weeds : Cardiospermum halicacabum Linn. and C. grandiflorum Sw.
Members of the balloon vine genus, Cardiospermum, have been extensively moved around the globe as medicinal and horticultural species, two of which are now widespread invasive species; C. grandiflorum and C. halicacabum. A third species, C. corindum, may also have significant invasion potential. However, in some regions the native status of these species is not clear, hampering management. For example, in South Africa it is unknown whether C. halicacabum and C. corindum are native, and this is a major constraint to on-going biological control programmes against invasive C. grandiflorum. We review the geography, biology and ecology of selected members of the genus with an emphasis on the two most widespread invaders, C. halicacabum and C. grandiflorum. Specifically, we use molecular data to reconstruct a phylogeny of the group in order to shed light on the native ranges of C. halicacabum and C. corindum in southern Africa. Phylogenetic analyses indicate that southern African accessions of these species are closely related to South American taxa indicating human-mediated introduction and/or natural long distance dispersal. Then, on a global scale we use species distribution modelling to predict potential suitable climate regions where these species are currently absent. Native range data were used to test the accuracy with which bioclimatic modelling can identify the known invasive ranges of these species. Results show that Cardiospermum species have potential to spread further in already invaded or introduced regions in Australia, Africa and Asia, underlining the importance of resolving taxonomic uncertainties for future management efforts. Bioclimatic modelling predicts Australia to have highly favourable environmental conditions for C. corindum and therefore vigilance against this species should be high. Species distribution modelling showed that native range data over fit predicted suitable ranges, and that factors other than climate influence establishment potential. This review opens the door to better understand the global biogeography of the genus Cardiospermum, with direct implications for management, while also highlighting gaps in current research
Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning.
BackgroundHuman immunodeficiency virus (HIV) and methamphetamine use commonly affect neurocognitive (NC) functioning. We evaluated the relationships between NC functioning and two fibroblast growth factors (FGFs) in volunteers who differed in HIV serostatus and methamphetamine dependence (MAD).MethodsA total of 100 volunteers were categorized into four groups based on HIV serostatus and MAD in the prior year. FGF-1 and FGF-2 were measured in cerebrospinal fluid by enzyme-linked immunosorbent assays along with two reference biomarkers (monocyte chemotactic protein [MCP]-1 and neopterin). Comprehensive NC testing was summarized by global and domain impairment ratings.ResultsSixty-three volunteers were HIV+ and 59 had a history of MAD. FGF-1, FGF-2, and both reference biomarkers differed by HIV and MAD status. For example, FGF-1 levels were lower in subjects who had either HIV or MAD than in HIV- and MAD- controls (P=0.003). Multivariable regression identified that global NC impairment was associated with an interaction between FGF-1 and FGF-2 (model R(2)=0.09, P=0.01): higher FGF-2 levels were only associated with neurocognitive impairment among subjects who had lower FGF-1 levels. Including other covariates in the model (including antidepressant use) strengthened the model (model R(2)=0.18, P=0.004) but did not weaken the association with FGF-1 and FGF-2. Lower FGF-1 levels were associated with impairment in five of seven cognitive domains, more than FGF-2, MCP-1, or neopterin.ConclusionThese findings provide in vivo support that HIV and MAD alter expression of FGFs, which may contribute to the NC abnormalities associated with these conditions. These cross-sectional findings cannot establish causality and the therapeutic benefits of recombinant FGF-1 need to be investigated
Future asymptotic expansions of Bianchi VIII vacuum metrics
Bianchi VIII vacuum solutions to Einstein's equations are causally
geodesically complete to the future, given an appropriate time orientation, and
the objective of this article is to analyze the asymptotic behaviour of
solutions in this time direction. For the Bianchi class A spacetimes, there is
a formulation of the field equations that was presented in an article by
Wainwright and Hsu, and in a previous article we analyzed the asymptotic
behaviour of solutions in these variables. One objective of this paper is to
give an asymptotic expansion for the metric. Furthermore, we relate this
expansion to the topology of the compactified spatial hypersurfaces of
homogeneity. The compactified spatial hypersurfaces have the topology of
Seifert fibred spaces and we prove that in the case of NUT Bianchi VIII
spacetimes, the length of a circle fibre converges to a positive constant but
that in the case of general Bianchi VIII solutions, the length tends to
infinity at a rate we determine.Comment: 50 pages, no figures. Erronous definition of Seifert fibred spaces
correcte
Association of weekly suicide rates with temperature anomalies in two different climate types
Annual suicide deaths outnumber the total deaths from homicide and war combined. Suicide is a complex behavioral endpoint, and a simple cause-and-effect model seems highly unlikely, but relationships with weather could yield important insight into the biopsychosocial mechanisms involved in suicide deaths. This study has been designed to test for a relationship between air temperature and suicide frequency that is consistent enough to offer some predictive abilities. Weekly suicide death totals and anomalies from Toronto, Ontario, Canada (1986-2009) and Jackson, Mississippi, USA (1980-2006) are analyzed for relationships by using temperature anomaly data and a distributed lag nonlinear model. For both analysis methods, anomalously cool weeks show low probabilities of experiencing high-end suicide totals while warmer weeks are more likely to experience high-end suicide totals. This result is consistent for Toronto and Jackson. Weekly suicide totals demonstrate a sufficient association with temperature anomalies to allow some prediction of weeks with or without increased suicide frequency. While this finding alone is unlikely to have immediate clinical implications, these results are an important step toward clarifying the biopsychosocial mechanisms of suicidal behavior through a more nuanced understanding of the relationship between temperature and suicide
Connecting does not necessarily mean learning: Course handbooks as mediating tools in school-university partnerships
This is the author's accepted manuscript (titled "Course handbooks as mediating tools in learning to teach"). The final published article is available from the link below. Copyright @ 2011 American Association of Colleges for Teacher Education.Partnerships between schools and universities in England use course handbooks to guide student teacher learning during long field experiences. Using data from a yearlong ethnographic study of a postgraduate certificate of education programme in one English university, the function of course handbooks in mediating learning in two high school subject departments (history and modern foreign languages) is analyzed. Informed by Cultural Historical Activity Theory, the analysis focuses on the handbooks as mediating tools in the school-based teacher education activity systems. Qualitative differences in the mediating functions of the handbooks-in-use are examined and this leads to a consideration of the potential of such tools for teacher learning in school–university partnerships. Following Zeichner’s call for rethinking the relationships between schools and universities, the article argues that strong structural connections between different institutional sites do not necessarily enhance student teacher learning
Observations of the Cosmic Microwave Background and Implications for Cosmology and Large Scale Structure
Observations of the Cosmic Microwave Background (CMB) are discussed, with
particular emphasis on current ground-based experiments and on future
satellite, balloon and interferometer experiments. Observational techniques and
the effects of contaminating foregrounds are highlighted. Recent CMB data is
used with large scale structure (LSS) data to constrain cosmological parameters
and the complementary nature of CMB, LSS and supernova distance data is
emphasized.Comment: 23 pages, 10 figures. Phil. Trans. R. Soc. Lond. A., 1998, in pres
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