Development of Mennonite music in the Congo: A study in musical thought

The purpose of this study was to examine musical thought among members of the Congolese Mennonite Church. Established and governed by missionaries, the music practices of the Church were initially modeled after Western services, which consisted of church choirs and four-part hymn singing. Congolese who chose to convert to Christianity had to adapt to a new musical system, which included not only properties of musical sound, but also concepts surrounding the music making experience, including what music is and what it has the power to accomplish. The church has now been in existence for over one hundred years, and musical changes have occurred in both sound and concept. This is an examination of those changes, with focus on the development of current forms and practices, the function of each form in the worship service, surrounding influences, and the points of debate that occurred with each stylistic shift. Additionally, the nature of music making and the boundaries between the sacred and profane are discussed. This was accomplished through traveling to DR Congo and employing the ethnographic techniques of interview and observation. Fifty men and women from thirteen different congregations were consulted, and observations occurred at choir rehearsals and church worship services, all within the city of Kinshasa, which is both the capital of DR Congo and its largest city. As a result, four categories of music were identified, as well as descriptions for their development and function in the worship service. A timeline was created from 1911 to the present, demonstrating the shift from one style of music to four styles of music. The timeline also encompasses surrounding influences and the topics for debate that accompanied each style change. Music making and musical thought were determined by numerous factors, both musical and extra-musical. The overarching purpose of music making has not changed from the mission era, but the boundaries that were initially established by missionaries were later challenged by Pentecostal churches in Kinshasa, especially churches in the revivalist movement. Additionally, in the midst of change, Congolese Mennonites continue to write their own songs and explore sonic possibilities, creating sounds that are distinct to each congregation and choir

Changing the Paradigm for Pesticide Resistance Management

Collaborative action on the part of all stakeholders in pest management is essential to effectively address the challenges of pesticide resistance. The US Environmental Protection Agency, through its Pesticide Program Dialogue Committee, recently posted a report on pesticide resistance management and the role the Agency can play in these efforts. In this perspectives piece, we commend the Agency for acknowledging these needs, and encourage implementation of the recommendations. We urge all stakeholders to follow the example set by EPA to engage openly, listen to other stakeholders, and determine their role as part of the broader community that is needed to address the challenges of resistance. Our contention is that pesticide resistance will continue to escalate until all stakeholders evaluate their roles in resistance management and work together as a community to influence effective management

VARIANCE AS A FACTOR EFFECT IN INTERDISCIPLINARY STUDIES OF AGRICULTURAL SYSTEMS

Studies of interrelationships among factors typically focus on factor effects related to the mean response. In some instances, response variances, as well as, or even rather than, response means, may be affected by the factors under consideration. In this paper, generalizations of Levene\u27s test and the Jackknife test to two-factor experimental designs are studied via simulation studies to assess their ability to identify differences in the variance as an interaction effect or as a factor main effect. These tests are then applied to a particular example where relationships between chile plants and two prominent pests of chile plants -nematodes and yellow nutsedge -- are under study. This example illustrates the utility of these tests in studying relationships among factors in agricultural systems

Dietary manipulation and caloric restriction in the development of mouse models relevant to neurological diseases

AbstractManipulation of diet such as increasing the level of fat or inducing insulin resistance has been shown to exacerbate the pathology in several animal models of neurological disease. Caloric restriction, however, has been demonstrated to extend the life span of many organisms. Reduced calorie consumption appears to increase the resistance of neurons to intracellular and extracellular stress and consequently improves the behavioural phenotype in animal models of neurological diseases, such as Alzheimer's disease. We review the evidence from a variety of mouse models that diet is a risk factor that can significantly contribute to the development of neurological diseases

DETERMINING THE EFFECTIVESNESS OF INCLUDING SPATIAL INFORMATION INTO A NEMATODE/NUTSEDGE PEST COMPLEX MODEL

An experiment was performed in 2005-2006 to determine if a nematode-resistant variety of alfalfa (Medicago sativa L.) can effectively reduce the pest complex consisting of yellow and purple nutsedge (YNS, Cyperus esculentus L. and PNS, C. rotundus L.) and the southern rootknot nematode (SRKN, Meloidogyne incognita (Kofoid & White) Chitwood). The alfalfa field, which had a history of severe infestation from both species of nutsedge and SRKN, was divided into 1m x 2m quadrats. In May, July and September of each year, eighty quadrats were randomly selected and counts of PNS, YNS and a soil sample (analyzed for the count of juvenile SRKN) were taken from each quadrat. Poisson regression models were fitted to see if information about YNS and PNS counts could be used to predict juvenile SRKN counts. In this study, two different ways to incorporate spatial information of quadrat locations within the field were examined to try to reduce over-dispersion in the original regression models. Spatial coordinates were first treated as fixed effects and then second, in separate models, as random effects using various spatial variance-covariance structures. Models with spatial coordinates as both fixed and random effects failed to converge, possibly because of small (n=80) sample size. The results of spatial models were compared to the original Poisson models, but there was not an effective way of comparing random-effects models with fixed-effects models. For this data, the use of spatial information did not improve the original model consistently. This may be partly because of the nature of the experiment. As hoped, the alfalfa crop effectively reduced YNS, PNS, and SRKN counts. The spatial information was generally more useful earlier in the experiment when the YNS, PNS, and SRKN populations were denser

The Economic Feasibility of Forming A California Wheat Cooperative

Recent concerns relative to California farm gate prices for wheat and a lack of profitability in wheat production has been expressed by a group of California wheat growers. Their dissatisfaction has resulted in their consideration to form a California wheat grower cooperative. The cooperative would become the marketing agent for the growers and potentially allow growers to pool their production for greater market power as well as capture profits beyond the farm gate. Two feasibility issues are addressed by the study: 1) The organizational feasibility of forming the cooperative, and 2) The economic feasibility of a California wheat growers cooperative engaging in value-added marketing opportunities upstream from the farm gate that would result in increased the return to wheat grower production. The objective of the study was to evaluate those feasibilities

MODELING THE ROOT-KNOT NEMATODE/NUTSEDGE PEST COMPLEX: PERSPECTIVES FROM WEED SCIENCE, NEMATOLOGY AND STATISTICS

Previous research by the authors has established that southern root-knot nematode (SRKN, Meloidogyne incognita (Kofoid & White) Chitwood) and yellow and purple nutsedge (YNS, Cyperus esculentus L. and PNS, C. rotundus L.) form a pest-complex that adversely affects a wide variety of crops in the southern and western U.S. These pests appear to have co-evolved a mutually-beneficial relationship that promotes the survival of both nematodes and weeds to the detriment of crops. Traditional management has usually targeted one pest at a time, but managing this pest complex requires that all members of the complex be managed simultaneously. A series of experiments was performed to determine if this specific pest complex could be managed through crop-rotation using a non-dormant M. incognita-resistant variety of alfalfa (Medicago sativa) which can aggressively compete with, and hence decrease, occurrence of both species of nutsedges (NS), and subsequently decrease SRKN by decreasing the availability of root systems of host plants. A previous journal article discussed predicting counts of SRKN second-stage juveniles (SRKN-J2) as a function of YNS and PNS plant counts from a two-year alfalfa rotation experiment, using the Poisson distribution and a scale parameter to handle problems of overdispersion. In this paper, we examine three generalizations of the Poisson distribution that allow for the count variance being larger than the mean count: the Generalized Poisson, the Zero-Inflated Poisson (ZIP), and the Poisson Hurdle. The ZIP and Hurdle Poisson distributions both account for zero counts as a separate part of the distribution, while the Generalized Poisson incorporates a separate parameter that increases the variance relative to the mean. Different biological scenarios are presented for which each of these three general Poisson distributions might be logically appropriate. In addition, we use the alfalfa rotation data to present comparisons of fitted regression models of the three general Poisson distributions to the results from the previous analysis using the Poisson. For this data, there was no single probability distribution that worked best for all six sampling dates (three in each of the two years). This is not surprising in that over time the alfalfa rotation was, as planned, decreasing both nutsedge and nematode counts, thus presenting a moving target for the modeling process

Epstein-Barr virus and human papillomavirus serum antibodies define the viral status of nasopharyngeal carcinoma in a low endemic country

Epstein-Barr virus (EBV) causes nasopharyngeal carcinoma (NPC) in endemic regions, where almost every tumor is EBV-positive. In Western populations, NPC is rare, and human papillomavirus infection (HPV) has been suggested as another viral cause. We validated multiplex serology with molecular tumor markers, to define EBV-positive, HPV-positive, and EBV-/HPV-negative NPCs in the United Kingdom, and analyzed survival differences between those groups. Sera from NPC cases (N = 98) and age- and sex-matched controls (N = 142) from the Head and Neck 5000 clinical cohort study were analyzed. IgA and IgG serum antibodies against 13 EBV antigens were measured and compared with EBER in situ hybridization (EBER-ISH) data of 41 NPC tumors (29 EBER-ISH positive, 12 negative). IgG antibodies to EBV LF2 correctly diagnosed EBV-positive NPCs in 28 of 29 cases, while all EBER-ISH negative NPCs were seronegative to LF2 IgG (specificity = 100%, sensitivity = 97%). HPV early antigen serology was compared to HPV molecular markers (p16 expression, HPV DNA and RNA) available for 41 NPCs (13 positive, 28 negative). Serology matched molecular HPV markers in all but one case (specificity = 100%, sensitivity = 92%). EBV and HPV infections were mutually exclusive. Overall, 67% of the analyzed NPCs were defined as EBV-positive, 18% as HPV-positive and 14% as EBV/HPV-negative. There was no statistical evidence of a difference in survival between the three groups. These data provide evidence that both, EBV-positive and HPV-positive NPCs are present in a low incidence country, and that EBV and HPV serum antibodies correlate with the viral status of the tumor.</p

Reproductive and Hormonal Risk Factors for Ductal Carcinoma In situ of the Breast

One-fifth of all newly diagnosed breast cancer cases are ductal carcinoma in situ (DCIS), but little is known about DCIS risk factors. Recent studies suggest that some subtypes of DCIS (high grade, or comedo) share histopathologic and epidemiologic characteristics with invasive disease, while others (medium or low grade, or non-comedo) show different patterns. To investigate whether reproductive and hormonal risk factors differ among comedo and non-comedo types of DCIS and invasive breast cancer, we used a population-based case-control study of 1808 invasive and 446 DCIS breast cancer cases and their age and race frequency-matched controls (1564 invasive and 458 DCIS). Three or more full-term pregnancies showed a strong inverse association with comedo-type DCIS (odds ratio (OR) = 0.53, 95% confidence interval (CI) = 0.30, 0.95) and a weaker inverse association for non-comedo DCIS (OR = 0.73, 95% CI = 0.42, 1.27). Several risk factors (age at first full-term pregnancy, breastfeeding, and age at menopause) demonstrated similar associations for comedo-type DCIS and invasive breast cancer, but different associations for non-comedo DCIS. Ten or more years of oral contraceptive showed a positive association with comedo-type DCIS (OR = 1.31, 05% CI 0.70, 2.47) and invasive breast cancer (OR = 2.33, 95% CI 1.06, 5.09), but an inverse association for noncomedo DCIS (OR = 0.51, 95% CI 0.25-1.04). Our results support the theory that comedo-type DCIS may share hormonal and reproductive risk factors with invasive breast cancer, while the etiology of non-comedo DCIS deserves further investigation

Operational Research in Education

Operational Research (OR) techniques have been applied, from the early stages of the discipline, to a wide variety of issues in education. At the government level, these include questions of what resources should be allocated to education as a whole and how these should be divided amongst the individual sectors of education and the institutions within the sectors. Another pertinent issue concerns the efficient operation of institutions, how to measure it, and whether resource allocation can be used to incentivise efficiency savings. Local governments, as well as being concerned with issues of resource allocation, may also need to make decisions regarding, for example, the creation and location of new institutions or closure of existing ones, as well as the day-to-day logistics of getting pupils to schools. Issues of concern for managers within schools and colleges include allocating the budgets, scheduling lessons and the assignment of students to courses. This survey provides an overview of the diverse problems faced by government, managers and consumers of education, and the OR techniques which have typically been applied in an effort to improve operations and provide solutions