Detecting Neutrino Magnetic Moments with Conducting Loops

It is well established that neutrinos have mass, yet it is very difficult to measure those masses directly. Within the standard model of particle physics, neutrinos will have an intrinsic magnetic moment proportional to their mass. We examine the possibility of detecting the magnetic moment using a conducting loop. According to Faraday's Law of Induction, a magnetic dipole passing through a conducting loop induces an electromotive force, or EMF, in the loop. We compute this EMF for neutrinos in several cases, based on a fully covariant formulation of the problem. We discuss prospects for a real experiment, as well as the possibility to test the relativistic formulation of intrinsic magnetic moments.Comment: 6 pages, 4 b/w figures, uses RevTe

The Nature of the Optical Light in Seyfert 2 Galaxies with Polarized Continuum

We investigate the nature of the optical continuum and stellar population in the central kpc of the Seyfert 2s Mrk 348, Mrk 573, NGC 1358 and Mrk 1210 using long-slit spectra obtained along the radio or extended emission axis. These galaxies are known to have polarized continuum-including polarized broad lines in Mrk 348 and Mrk 1210--and previous studies indicate featureless continuum (FC) contributions in the 20-50% range at 5500 A. Nevertheless, our measurements of the equivalent widths of absorption lines and continuum ratios as a function of distance from the nuclei show no dilution of the lines nor bluening of the spectrum, as expected if a blue FC was present at the nucleus in the above proportions. We investigate one possibility to account for this effect: that the stellar population at the nucleus is the same as that from the surrounding bulge and dominates the nuclear light. A spectral analysis confirms that this hypothesis works for Mrk 348, NGC 1358 and Mrk 1210, for which we find stellar contributions at the nucleus larger than 90% at all wavelengths. We find that a larger stellar population contribution to the nuclear spectra can play the role of the ``second FC'' source inferred from previous studies. Stellar population synthesis shows that the nuclear regions of Mrk 348 and Mrk 1210 have important contributions of young to intermediate age stars (0--100 Myr), not present in templates of elliptical galaxies. In the case of Mrk 1210, this is further confirmed by the detection of a ``Wolf-Rayet feature'' in the nuclear emission-line spectrum.Comment: ApJ, accepted. Uses aaspp4.sty. [22 pages

High Rayleigh number convection with double diffusive fingers

An electrodeposition cell is used to sustain a destabilizing concentration difference of copper ions in aqueous solution between the top and bottom boundaries of the cell. The resulting convecting motion is analogous to Rayleigh-B\'enard convection at high Prandtl numbers. In addition, a stabilizing temperature gradient is imposed across the cell. Even for thermal buoyancy two orders of magnitude smaller than chemical buoyancy, the presence of the weak stabilizing gradient has a profound effect on the convection pattern. Double diffusive fingers appear in all cases. The size of these fingers and the flow velocities are independent of the height of the cell, but they depend on the ion concentration difference between top and bottom boundaries as well as on the imposed temperature gradient. The scaling of the mass transport is compatible with previous results on double diffusive convection

Apsidal motion in the massive binary HD152218

Massive binary systems are important laboratories in which to probe the properties of massive stars and stellar physics in general. In this context, we analysed optical spectroscopy and photometry of the eccentric short-period early-type binary HD 152218 in the young open cluster NGC 6231. We reconstructed the spectra of the individual stars using a separating code. The individual spectra were then compared with synthetic spectra obtained with the CMFGEN model atmosphere code. We furthermore analysed the light curve of the binary and used it to constrain the orbital inclination and to derive absolute masses of 19.8 +/- 1.5 and 15.0 +/- 1.1 solar masses. Combining radial velocity measurements from over 60 years, we show that the system displays apsidal motion at a rate of (2.04^{+.23}_{-.24}) degree/year. Solving the Clairaut-Radau equation, we used stellar evolution models, obtained with the CLES code, to compute the internal structure constants and to evaluate the theoretically predicted rate of apsidal motion as a function of stellar age and primary mass. In this way, we determine an age of 5.8 +/- 0.6 Myr for HD 152218, which is towards the higher end of, but compatible with, the range of ages of the massive star population of NGC 6231 as determined from isochrone fitting.Comment: Accepted for publication in Astronomy & Astrophysic

The Atypical Stimulant and Nootropic Modafinil Interacts with the Dopamine Transporter in a Different Manner than Classical Cocaine-Like Inhibitors

Modafinil is a mild psychostimulant with pro-cognitive and antidepressant effects. Unlike many conventional stimulants, modafinil has little appreciable potential for abuse, making it a promising therapeutic agent for cocaine addiction. The chief molecular target of modafinil is the dopamine transporter (DAT); however, the mechanistic details underlying modafinil's unique effects remain unknown. Recent studies suggest that the conformational effects of a given DAT ligand influence the magnitude of the ligand's reinforcing properties. For example, the atypical DAT inhibitors benztropine and GBR12909 do not share cocaine's notorious addictive liability, despite having greater binding affinity. Here, we show that the binding mechanism of modafinil is different than cocaine and similar to other atypical inhibitors. We previously established two mutations (W84L and D313N) that increase the likelihood that the DAT will adopt an outward-facing conformational state—these mutations increase the affinity of cocaine-like inhibitors considerably, but have little or opposite effect on atypical inhibitor binding. Thus, a compound's WT/mutant affinity ratio can indicate whether the compound preferentially interacts with a more outward- or inward-facing conformational state. Modafinil displayed affinity ratios similar to those of benztropine, GBR12909 and bupropion (which lack cocaine-like effects in humans), but far different than those of cocaine, β-CFT or methylphenidate. Whereas treatment with zinc (known to stabilize an outward-facing transporter state) increased the affinity of cocaine and methylphenidate two-fold, it had little or no effect on the binding of modafinil, benztropine, bupropion or GBR12909. Additionally, computational modeling of inhibitor binding indicated that while β-CFT and methylphenidate stabilize an “open-to-out” conformation, binding of either modafinil or bupropion gives rise to a more closed conformation. Our findings highlight a mechanistic difference between modafinil and cocaine-like stimulants and further demonstrate that the conformational effects of a given DAT inhibitor influence its phenomenological effects

Functional variants of DOG1 control seed chilling responses and variation in seasonal life-history strategies in Arabidopsis thaliana.

The seasonal timing of seed germination determines a plant's realized environmental niche, and is important for adaptation to climate. The timing of seasonal germination depends on patterns of seed dormancy release or induction by cold and interacts with flowering-time variation to construct different seasonal life histories. To characterize the genetic basis and climatic associations of natural variation in seed chilling responses and associated life-history syndromes, we selected 559 fully sequenced accessions of the model annual species Arabidopsis thaliana from across a wide climate range and scored each for seed germination across a range of 13 cold stratification treatments, as well as the timing of flowering and senescence. Germination strategies varied continuously along 2 major axes: 1) Overall germination fraction and 2) induction vs. release of dormancy by cold. Natural variation in seed responses to chilling was correlated with flowering time and senescence to create a range of seasonal life-history syndromes. Genome-wide association identified several loci associated with natural variation in seed chilling responses, including a known functional polymorphism in the self-binding domain of the candidate gene DOG1. A phylogeny of DOG1 haplotypes revealed ancient divergence of these functional variants associated with periods of Pleistocene climate change, and Gradient Forest analysis showed that allele turnover of candidate SNPs was significantly associated with climate gradients. These results provide evidence that A. thaliana's germination niche and correlated life-history syndromes are shaped by past climate cycles, as well as local adaptation to contemporary climate